Long-term follow-up of hepatitis B virus and hepatitis C virus replicative levels in chronic hepatitis patients coinfected with both viruses.

abstract：:To characterize cytotoxic T lymphocytes (CTLs) that appeared in circulation during lamivudine therapy, we analyzed HBV-specific CTLs using HLA-A24 tetramer and HBcAg-specific Th1 cells in patients receiving lamivudine therapy. Six patients (HLA-A24(+)) with chronic hepatitis B, six patients (HLA-A24(-)) with chronic h...

journal_title：Journal of medical virology

authors： Kondo Y,Asabe S,Kobayashi K,Shiina M,Niitsuma H,Ueno Y,Kobayashi T,Shimosegawa T

更新日期：2004-11-01 00:00:00

abstract：:The multiplication of HSV-1 and HSV-2 strains in the heart and the corresponding dorsal root ganglia (DRG) was examined in experimentally infected mice. Infectious HSV-1 was recovered from the heart between the second and fourth day after inoculation and 3 days later from the DRG. Both the heart and DRG yielded infect...

journal_title：Journal of medical virology

authors： Grodums EI,Kuling PJ,Zbitnew A

更新日期：1981-01-01 00:00:00

abstract：:Avidity maturation of IgG antibody responses directed against the structural proteins of rubella virus (E1, E2, and C) as well as whole rubella virus (RV) was assessed at sequential time intervals in 7 individuals following serologically confirmed wild rubella infection. Individual structural proteins were purified fr...

journal_title：Journal of medical virology

authors： Mauracher CA,Mitchell LA,Tingle AJ

更新日期：1992-03-01 00:00:00

abstract：:Paired serum and saliva samples were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) for the presence of human immunodeficiency virus (HIV) antibodies. The study group included 36 individuals known to be HIV seropositive and 14 healthy, seronegative controls. HIV antibodies were detected in a...

journal_title：Journal of medical virology

authors： Holmström P,Syrjänen S,Laine P,Valle SL,Suni J

更新日期：1990-04-01 00:00:00

abstract：:The human cytomegalovirus (HCMV), a member of the Herpesviridae, is the most frequent cause of congenital virus infections and a major cause of morbidity and mortality in immunocompromised patients. Due to the lack of an appropriate animal model, insight into the pathogenesis of HCMV infections originates primarily fr...

journal_title：Journal of medical virology

authors： Bissinger AL,Sinzger C,Kaiserling E,Jahn G

更新日期：2002-06-01 00:00:00

abstract：:During the 1976 Ebola virus outbreak in Sudan, the investigations team gained the impression that fewer haemorrhagic manifestations and few fatalities occurred during the later stages of the epidemic after the virus had undergone several generations in man. This impression was also noted in guinea pigs experimentally ...

journal_title：Journal of medical virology

authors： Bowen ET,Platt GS,Lloyd G,Raymond RT,Simpson DI

更新日期：1980-01-01 00:00:00

abstract：:Human parainfluenza virus 3 (HPIV-3) is a leading cause of respiratory disease in children worldwide. Previous sequence analyses of the entire virus genome, among different HPIV-3 strains, demonstrated that HN is the most variable gene. There is a dearth of data on HPIV-3 strains circulating in Saudi Arabia. In this r...

journal_title：Journal of medical virology

authors： Almajhdi FN,Alshaman MS,Amer HM

更新日期：2012-08-01 00:00:00

abstract：:Despite the success of antivirals in preventing clinically overt CMV disease in cardiac allograft recipients, sub-clinical active CMV infection remains a major concern because of its association with allograft rejection and vasculopathy. The measurement of CMV specific T-cell responses is a promising approach to asses...

journal_title：Journal of medical virology

authors： Kirchner A,Hoffmeister B,Cherepnev-G G,Fuhrmann S,Streitz M,Lachmann R,Bunde T,Meij P,Schönemann C,Hetzer R,Lehmkuhl HB,Volkmer-Engert R,Volk HD,Gratama JW,Kern F

更新日期：2008-09-01 00:00:00

abstract：:Little information about immunity to respiratory syncytial virus (RSV) and disease pathogenesis in elderly persons exists. Humoral immunity to RSV was assessed in 41 young, 56 healthy elderly, and 49 frail elderly adults by measuring baseline RSV specific IgG by enzyme immunoassay (EIA) and microneutralization assay (...

journal_title：Journal of medical virology

authors： Falsey AR,Walsh EE,Looney RJ,Kolassa JE,Formica MA,Criddle MC,Hall WJ

更新日期：1999-10-01 00:00:00

abstract：:It remains unclear if China's current HIV antibody testing algorithm misses a substantial number of HIV infected individuals. Of 196 specimens with indeterminate or negative results on HIV western blot (WB) retrospectively examined by HIV-1 nucleic acid test (NAT), 67.57% (75/111) of indeterminate WB samples, and 16.4...

journal_title：Journal of medical virology

authors： Liu MQ,Zhu ZR,Kong WH,Tang L,Peng JS,Wang X,Xu J,Schilling RF,Cai T,Zhou W

更新日期：2016-08-01 00:00:00

abstract：:Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 ch...

journal_title：Journal of medical virology

authors： Ahn JG,Choi SY,Kim DS,Kim KH

更新日期：2014-12-01 00:00:00

abstract：:Serum levels of interleukin-6 (IL-6) are elevated in acute and chronic hepatitis B patients. The effect of IL-6 and its transcription factor of NF-IL6 (a nuclear factor for IL-6) on hepatitis B virus (HBV) enhancer 1 (Enh1), which controls HBV X expression, were investigated in HepG2 cells. Twenty ng/ml of IL-6 increa...

journal_title：Journal of medical virology

authors： Ohno H,Kaneko S,Kobayashi K,Murakami S

更新日期：1997-08-01 00:00:00

abstract：:Enterovirus 71 H (E71 H), an isolate from an adult patient with hand-food-mouth disease (HFMD) in China, was serologically similar to the prototype strain E71 BrCr, which was isolated from a patient with aseptic meningitis. The study further analyzed the similarity of E71 H to E71 BrCr at the 5'-noncoding region (NCR)...

journal_title：Journal of medical virology

authors： Zheng ZM,He PJ,Caueffield D,Neumann M,Specter S,Baker CC,Bankowski MJ

更新日期：1995-10-01 00:00:00

abstract：:BKPyV replication is a risk factor for the development of polyomavirus-associated nephropathy in kidney transplant recipients. Here, the case of a 42 years old Caucasian patient is described who developed a kidney allograft failure because of uncontrolled BKPyV replication 7 months after transplant despite a strong re...

journal_title：Journal of medical virology

authors： Anselmo A,Prezioso C,Saccà FA,Di Lella FM,Palmieri G,Tisone G,Pietropaolo V,Ciotti M

更新日期：2019-09-01 00:00:00

abstract：:The burden of herpes zoster may be related to patients' immunity, although this has not been studied extensively. This hypothesis was tested in a matched case-control study of patients with herpes zoster who sought treatment at one of seven university hospitals in Korea from January 1, 2007, to December 31, 2010. Pati...

journal_title：Journal of medical virology

authors： Choi WS,Kwon SS,Lee J,Choi SM,Lee JS,Eom JS,Sohn JW,Choeng HJ

更新日期：2014-03-01 00:00:00

abstract：:Seoul virus (SEOV) is the etiologic agent of hemorrhagic fever with renal syndrome. It is carried by brown rats (Rattus norvegicus), a commensal rodent that closely cohabitates with humans in urban environments. SEOV has a worldwide distribution, and in Europe, it has been found in rats in UK, France, Sweden, and Belg...

journal_title：Journal of medical virology

authors： Ling J,Verner-Carlsson J,Eriksson P,Plyusnina A,Löhmus M,Järhult JD,van de Goot F,Plyusnin A,Lundkvist Å,Sironen T

更新日期：2019-05-01 00:00:00

abstract：:Throughout most of the last decade, B/Yamagata/16/88-lineage influenza viruses were predominant among the B isolates circulating worldwide, whereas B/Victoria/2/87-lineage viruses were isolated infrequently and restricted geographically to eastern Asia. During the 2001-02 influenza season, B/Victoria/2/87-lineage viru...

journal_title：Journal of medical virology

authors： Puzelli S,Frezza F,Fabiani C,Ansaldi F,Campitelli L,Lin YP,Gregory V,Bennett M,D'Agaro P,Campello C,Crovari P,Hay A,Donatelli I

更新日期：2004-12-01 00:00:00

abstract：:The long-term efficacy of lamivudine therapy in patients with hepatitis B virus (HBV) infection is still not clear. In this study, 20 non-cirrhotic Japanese patients infected with HBV received lamivudine therapy for more than 1 year and were followed for a median period of 8.5 years (range, 6.7-8.7 years). The rates o...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2005-04-01 00:00:00

abstract：:Hepatitis C Virus (HCV) NS3 protease is an attractive target for antiviral agent development because it is required for viral replication. Because a stable cell culture system or small animal model to study HCV replication is not readily available, we constructed an in vitro model allowing the investigation of NS3 tra...

journal_title：Journal of medical virology

authors： Heintges T,Encke J,zu Putlitz J,Wands JR

更新日期：2001-12-01 00:00:00

abstract：:Recent evidence suggested that neurological manifestations occur in patients with a severe form of coronavirus disease (COVID-19). On the basis of this issue, neurologists are very concerned about patients with neurological disorders, especially multiple sclerosis (MS), as consumers of immunosuppressive or immune-modu...

journal_title：Journal of medical virology

authors： Rostami Mansoor S,Ghasemi-Kasman M

更新日期：2020-10-12 00:00:00

abstract：:A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...

journal_title：Journal of medical virology

authors： Chen RW,Piiparinen H,Seppänen M,Koskela P,Sarna S,Lappalainen M

更新日期：2001-10-01 00:00:00

abstract：:Between 1999 and 2007 1,388 stool specimens from patients with acute flaccid paralysis or aseptic meningitis were submitted to the Austrian reference laboratory for poliomyelitis. Samples (201) yielded non-poliovirus enterovirus in culture. One hundred eighty-one viruses were available for typing and 78 isolates which...

journal_title：Journal of medical virology

authors： Ortner B,Huang CW,Schmid D,Mutz I,Wewalka G,Allerberger F,Yang JY,Huemer HP

更新日期：2009-02-01 00:00:00

abstract：:We compared characteristics of patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA to those of patients with GBV-C/HGV E2-antibody. GBV-C/HGV RNA and GBV-C/HGV antibody were assayed in 83 persons with hemophilia using a reverse transcription-polymerase chain reaction and an enzyme-linked immunosorbent assay, re...

journal_title：Journal of medical virology

authors： Toyoda H,Takahashi I,Fukuda Y,Hayakawa T,Takamatsu J

更新日期：2000-01-01 00:00:00

abstract：:Hepatitis C Virus (HCV) genotype 4 predominates in Middle East and Central Africa countries. Recently, it has become also prevalent in Southern European countries where it is thought to have been introduced through immigration and the movement of intravenous drug users. In Italy, the prevalence of genotype 4 is partic...

journal_title：Journal of medical virology

authors： Ciccozzi M,Equestre M,Costantino A,Marascio N,Quirino A,Lo Presti A,Cella E,Bruni R,Liberto MC,Focà A,Pisani G,Zehender G,Ciccaglione AR

更新日期：2012-10-01 00:00:00

abstract：:Human hepatitis B virus (HBV) and hepatitis C virus (HCV) are two major etiologic agents of chronic hepatitis, which is closely related to the development of hepatocellular carcinoma (HCC). A possible involvement of HBV co-infection was investigated in ongoing HCV-related liver diseases in HCV-infected patients. A pre...

journal_title：Journal of medical virology

authors： Koike K,Kobayashi M,Gondo M,Hayashi I,Osuga T,Takada S

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:The unprecedented demand for testing for the ongoing coronavirus disease-2019 (COVID-19) pandemic caused by SARS-CoV-2 has led to an acute shortage and limited availability of test reagents for which pooling of samples has been recommended in areas with low prevalence. Considering the possibility of dilution ...

journal_title：Journal of medical virology

authors： Mohanty S,Ravindra A,Gupta K,Hallur V,Behera B,Mahaptra A,Saha S,Ranjan J,Payal P,Mohanty M,Rath S,Mishra B

更新日期：2020-10-21 00:00:00

abstract：:In the nine years since the Global Advisory Group of the Expanded Programme on Immunisation (WHO) set 1997 as the target for integrating hepatitis B vaccination into national immunisation programmes worldwide, 129 countries have included hepatitis B vaccine as part of their routine infant or adolescent immunisation pr...

journal_title：Journal of medical virology

authors： Van Damme P,Vorsters A

更新日期：2002-07-01 00:00:00

abstract：:Some international guidelines recommend evaluating the need to confirm positive anti-hepatitis C virus (HCV) antibody screening results by means of a more specific antibody or molecular biology test on the basis of a screening threshold value (such as the sample signal/cut-off ratio) that can predict the positivity of...

journal_title：Journal of medical virology

authors： De Paschale M,Manco MT,Arpino O,Ricucci V,Paganini A,Belvisi L,Cagnin D,Cerulli T,Cianflone A,Agrappi C,Mirri P,Clerici P

更新日期：2017-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) genotypes can be distinguished based on gene sequence differences in EBV nuclear antigens 2, 3A, 3B, and 3C, and the BZLF1 promoter zone (Zp). EBV subtypes and BZLF1 Zp variants were examined in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated h...

journal_title：Journal of medical virology

authors： Imajoh M,Hashida Y,Murakami M,Maeda A,Sato T,Fujieda M,Wakiguchi H,Daibata M

更新日期：2012-06-01 00:00:00

abstract：:Chitin in the form of microparticles (chitin microparticles, CMP) has been demonstrated to be a potent stimulator of macrophages, promoting T-helper-1 (Th1) activation and cytokine response. In order to examine the mucosal adjuvant effect of CMP co-administered with influenza hemagglutinin (HA) vaccine against influen...

journal_title：Journal of medical virology

authors： Hasegawa H,Ichinohe T,Strong P,Watanabe I,Ito S,Tamura S,Takahashi H,Sawa H,Chiba J,Kurata T,Sata T

更新日期：2005-01-01 00:00:00