Hepatitis B virus DNA is frequently found in liver biopsy samples from hepatitis C virus-infected chronic hepatitis patients.

Abstract:

:Human hepatitis B virus (HBV) and hepatitis C virus (HCV) are two major etiologic agents of chronic hepatitis, which is closely related to the development of hepatocellular carcinoma (HCC). A possible involvement of HBV co-infection was investigated in ongoing HCV-related liver diseases in HCV-infected patients. A prevalence of anti-HBc in anti-HCV-positive/HBsAg-negative chronic hepatitis patients and a low copy number of HBV DNA were found in most of the liver biopsy samples of anti-HCV-positive/HBsAg-negative patients. The present data suggest that HBV co-infects frequently with HCV and may play an important role in the development of HCC in the anti-HCV-positive/HBsAg-negative patients with chronic hepatitis.

journal_name

J Med Virol

authors

Koike K,Kobayashi M,Gondo M,Hayashi I,Osuga T,Takada S

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

249-55

issue

4

eissn

0146-6615

issn

1096-9071

pii

10.1002/(SICI)1096-9071(199804)54:4<249::AID-JMV3>

journal_volume

54

pub_type

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