Abstract:
:Human hepatitis B virus (HBV) and hepatitis C virus (HCV) are two major etiologic agents of chronic hepatitis, which is closely related to the development of hepatocellular carcinoma (HCC). A possible involvement of HBV co-infection was investigated in ongoing HCV-related liver diseases in HCV-infected patients. A prevalence of anti-HBc in anti-HCV-positive/HBsAg-negative chronic hepatitis patients and a low copy number of HBV DNA were found in most of the liver biopsy samples of anti-HCV-positive/HBsAg-negative patients. The present data suggest that HBV co-infects frequently with HCV and may play an important role in the development of HCC in the anti-HCV-positive/HBsAg-negative patients with chronic hepatitis.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Koike K,Kobayashi M,Gondo M,Hayashi I,Osuga T,Takada Ssubject
Has Abstractpub_date
1998-04-01 00:00:00pages
249-55issue
4eissn
0146-6615issn
1096-9071pii
10.1002/(SICI)1096-9071(199804)54:4<249::AID-JMV3>journal_volume
54pub_type
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