Abstract:
:Faeces from 746 children less than 5 years old with acute gastroenteritis were screened for the presence of adenovirus particles or antigens by immunoelectron microscopy (IEM) and enzyme immunoassay (EIA). Thirty-five samples were positive by both IEM and EIA, two only by IEM, and two only by EIA, giving a total of 39 (5.2%) samples with positive results. Of these, 25 could be propagated in HEp2 cells and were neutralized by one of the antisera to adenovirus types 1 to 18. The remaining 14 samples could be propagated only in the 293 permanent line of human cells transformed by adenovirus type 5 DNA [Graham et al, 1977] and were not neutralized by antisera to adenovirus types 1 to 31. An EIA carried out by the antibody-capture technique, using antiserum specific for "enteric" adenoviruses [Johansson et al, 1979], gave positive results with all isolates that could be propagated only in 293 cells and with none of those capable of growing in HEp2 cells.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Leite JP,Pereira HG,Azeredo RS,Schatzmayr HGdoi
10.1002/jmv.1890150213subject
Has Abstractpub_date
1985-02-01 00:00:00pages
203-9issue
2eissn
0146-6615issn
1096-9071journal_volume
15pub_type
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2001-09-01 00:00:00
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更新日期:2020-08-06 00:00:00
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更新日期:2014-04-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
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更新日期:2006-08-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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