The variability of the serological response to SARS-corona virus-2: Potential resolution of ambiguity through determination of avidity (functional affinity).

abstract：:To assess the prevalence of HPV infection in the genital tracts of women with normal PAP smears, a random series of 109 women was reexamined using colposcopy, a further PAP smear, and punch biopsies taken from the cervix (in 33 cases), vagina (212 cases), and anus (20 cases). The biopsy material was examined using rou...

journal_title：Journal of medical virology

authors： Syrjänen S,Saastamoinen J,Chang FJ,Ji HX,Syrjänen K

更新日期：1990-08-01 00:00:00

abstract：:In the present study the reactivity of IgG and IgM antibodies against HSV-1 structural and nonstructural proteins was analyzed by Western blot analysis (WBA) and radioimmunoprecipitation followed by polyacrylamide gel electrophoresis (RIPA-PAGE). It was demonstrated that IgM and IgG antibodies were directed against vi...

journal_title：Journal of medical virology

authors： Kühn JE,Dunkler G,Munk K,Braun RW

更新日期：1987-10-01 00:00:00

abstract：:Preemptive therapy in hematopoietic cell transplantation is initiated by a diagnostic technique at first detection of cytomegalovirus (CMV). The aim of this study was to use the viral dynamics of CMV DNA viral to start preemptive therapy, and to prospectively compare the CMV viral load kinetics to pp65 antigenemia. Tw...

journal_title：Journal of medical virology

authors： Halfon P,Berger P,Khiri H,Martineau A,Pénaranda G,Merlin M,Faucher C

更新日期：2011-03-01 00:00:00

abstract：:We have previously reported that concanavalin A-immobilized polystyrene nanospheres (Con A-NS) could efficiently capture HIV-1 particles and that intranasal immunization with inactivated HIV-1-capturing nanospheres (HIV-NS) induced vaginal anti-HIV-1 IgA antibody response in mice. In this study, to evaluate the protec...

journal_title：Journal of medical virology

authors： Miyake A,Akagi T,Enose Y,Ueno M,Kawamura M,Horiuchi R,Hiraishi K,Adachi M,Serizawa T,Narayan O,Akashi M,Baba M,Hayami M

更新日期：2004-07-01 00:00:00

abstract：:The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...

journal_title：Journal of medical virology

authors： Ye Q,Wang B,Mao J,Fu J,Shang S,Shu Q,Zhang T

更新日期：2020-07-01 00:00:00

abstract：:Pregnant women are not screened for HBsAg and anti-HCV antibodies in many African countries. As there are few data concerning the prevalence of HBV, HDV, and HCV serological markers in Benin, the aim of this study was to evaluate their 2011 prevalence in pregnant women undergoing HIV screening in a rural area of north...

journal_title：Journal of medical virology

authors： De Paschale M,Ceriani C,Cerulli T,Cagnin D,Cavallari S,Ndayaké J,Zaongo D,Priuli G,Viganò P,Clerici P

更新日期：2014-08-01 00:00:00

abstract：:To provide background for future hepatitis A vaccine trials, sera were collected from 0- to 4-year-old Liberian infants and their mothers on two occasions an average of 14.75 months apart and tested for antibody to hepatitis A virus (anti-HAV). The prevalence of anti-HAV rose from 2.5% in infants 0-6 months of age to ...

journal_title：Journal of medical virology

authors： Prince AM,Brotman B,Richardson L,White T,Pollock N,Riddle J

更新日期：1985-04-01 00:00:00

abstract：:Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, we examined sera from patients and controls for anti...

journal_title：Journal of medical virology

authors： Cukor G,Blacklow NR,Braverman LE

更新日期：1982-01-01 00:00:00

abstract：:Hemodialysis patients are at risk for hepatitis C and B virus infections. This study investigated the prevalences and risk factors of HCV and HBV infection and the distribution of HCV genotypes among hemodialysis patients and their spouses. From August to November 2011, a cross-sectional study was conducted on 20 hemo...

journal_title：Journal of medical virology

authors： Su Y,Yan R,Duan Z,Norris JL,Wang L,Jiang Y,Xing W,Chen Y,Xiao Y,Li L,Tao J,Wang N

更新日期：2013-03-01 00:00:00

abstract：:Deletions and insertions in the hepatitis B virus (HBV) X region have been associated with severe forms of liver disease, including hepatocellular carcinoma (HCC). However, the molecular epidemiologic features of this virus have been described rarely. Deletions and insertions in the X region were determined by direct ...

journal_title：Journal of medical virology

authors： Lee SA,Mun HS,Kim H,Lee HK,Kim BJ,Hwang ES,Kook YH,Kim BJ

更新日期：2011-01-01 00:00:00

abstract：:During 2002, an upsurge in frequency of hepatitis A outbreaks among injecting drug users was observed in England and Wales. As lack of risk factor information and the high mobility of the cases made linkage of outbreaks difficult, the relationship of nucleotide sequences in the VP1/2PA junction of the hepatitis A viru...

journal_title：Journal of medical virology

authors： Ngui SL,Granerod J,Jewes LA,Crowcroft NS,Teo CG,2002 Hepatitis A Outbreaks Investigation Network.

更新日期：2008-07-01 00:00:00

abstract：:Most dengue virus (DENV) infections remain asymptomatic. This increases the risk of DENV transfusion transmission (TT-DENV) during outbreaks. We evaluated DENV viremia in 8475 blood donations assembled in minipools for the presence of DENV RNA. The tested samples were obtained between February and May, 2016, during a ...

journal_title：Journal of medical virology

authors： Slavov SN,Santos EV,Hespanhol MR,Rodrigues ES,Haddad R,Ubiali EMA,Covas DT,Kashima S

更新日期：2020-10-22 00:00:00

abstract：:Recent epidemiological and immunohistochemical studies have indicated a possible link between measles virus and inflammatory bowel disease (IBD). The aim of this study was to use a sensitive and robust method for the detection of measles virus RNA in IBD and control clinical samples. Peripheral blood mononuclear cells...

journal_title：Journal of medical virology

authors： Chadwick N,Bruce IJ,Schepelmann S,Pounder RE,Wakefield AJ

更新日期：1998-08-01 00:00:00

abstract：:The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is not clear if residual plasma HIVs during HAART can become predominant...

journal_title：Journal of medical virology

authors： Sahu GK,Paar D,Frost SD,Smith MM,Weaver S,Cloyd MW

更新日期：2009-01-01 00:00:00

abstract：:The aims of the present study were to confirm measles outbreaks by detection of measles-specific IgM antibodies, isolation of measles virus, and genetic characterization to document the circulating genotypes in Tamil Nadu. Eight outbreaks were reported from six districts of Tamil Nadu, India during the period Jan-Dec ...

journal_title：Journal of medical virology

authors： Ramamurty N,Raja D,Gunasekaran P,Varalakshmi E,Mohana S,Jin L

更新日期：2006-04-01 00:00:00

abstract：:Noroviruses (NoV) and sapoviruses (SaV) are recognized as important causes of acute gastroenteritis in children worldwide. In this study, the prevalence and genetic variability of NoV and SaV were determined in hospitalized children <5 years of age with acute gastroenteritis in Hanoi, Vietnam. A total of 501 fecal spe...

journal_title：Journal of medical virology

authors： Trang NV,Luan le T,Kim-Anh le T,Hau VT,Nhung le TH,Phasuk P,Setrabutr O,Shirley H,Vinjé J,Anh DD,Mason CJ

更新日期：2012-02-01 00:00:00

abstract：:Corticosteroid use in transplant recipients increases the incidence and severity of Kaposi's sarcoma (KS), a disease associated with KS-associated herpesvirus (KSHV) infection. Recently, the prototypic corticosteroid, hydrocortisone, was shown to directly induce lytic cycle reactivation of KSHV in latently-infected BC...

journal_title：Journal of medical virology

authors： Zoeteweij JP,Rinderknecht AS,Davis DA,Yarchoan R,Blauvelt A

更新日期：2002-03-01 00:00:00

abstract：:We report a male caucasian German pediatric patient of no Arab or Mediterranean ancestry with virus associated CNS lesions in Griscelli's syndrome (GS; McKusick No. 214450). The boy presented with recurrent infections, and meningitis with subsequent progressive signs of increased intracranial pressure leading to death...

journal_title：Journal of medical virology

authors： Wagner M,Müller-Berghaus J,Schroeder R,Sollberg S,Luka J,Leyssens N,Schneider B,Krueger GR

更新日期：1997-11-01 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：:Because Junin virus (JV) experimental encephalitis of mice and rats is characterized by mild histopathological changes that do not seem to justify per se lethality after intracerebral infection, such a murine model seems adequate to investigate the potential role of inducible nitric oxide synthase (iNOS) as a pathogen...

journal_title：Journal of medical virology

authors： Gómez RM,Yep A,Schattner M,Berría MI

更新日期：2003-01-01 00:00:00

abstract：:A sensitive microtitre radioimmunoassay was developed for detection of IgM antibodies to delta antigen. The assay was based on the selective binding of IgM from test sera to antihuman IgM (u-chain specific) fixed to wells of a microtitre plate, and utilized delta antigen extracted from the liver of an experimentally i...

journal_title：Journal of medical virology

authors： Dimitrakakis M,Waters MJ,Wootton A,Gust I

更新日期：1986-12-01 00:00:00

abstract：:Multiple determinants are involved in the progression of human papillomavirus (HPV)-infected cervical lesion to invasive cancer. Human leukocyte antigen (HLA) polymorphism seems to play a role. This study examined the association between HLA-DRB1 polymorphism, high-risk HPV infection, and the development of cervical n...

journal_title：Journal of medical virology

authors： Chan PK,Cheung TH,Lin CK,Siu SS,Yim SF,Lo KW,Cheung JL,Tam AO,Tang JW

更新日期：2007-07-01 00:00:00

abstract：:A diabetogenic strain of coxsackievirus B4 of human origin has been purified to study its biochemistry and diabetogenicity. Tissue culture cells infected with the virus contain two distinct types of particles--virions and membrane-bound virions (MBV). MBVs are lighter (p = 1.29) than virions (p = 1.34), and they conta...

journal_title：Journal of medical virology

authors： Chatterjee NK,Nejman C,Gerling I

更新日期：1988-09-01 00:00:00

abstract：:A highly sensitive two-step polymerase chain reaction (PCR) method was evaluated for detection of human immunodeficiency virus type 1 (HIV-1) DNA in clinical specimens. The product resulting from the first amplification reaction is used as the template for the second PCR with an internal (nested) primer pair. Even whe...

journal_title：Journal of medical virology

authors： Zazzi M,Romano L,Brasini A,Valensin PE

更新日期：1992-11-01 00:00:00

abstract：:HCV strains belonging to genotype 4 may be gaining endemicity across Continental Europe but the extent of their spread in the United Kingdom is unknown. Sera referred from patients attending hospitals in England between 2004 through 2008 were characterised. A total of 243 sera carried HCV genotype 4. The most common s...

journal_title：Journal of medical virology

authors： Ngui SL,Brant L,Markov PV,Tung JP,Pybus OG,Teo CG,Ramsay ME

更新日期：2015-03-01 00:00:00

abstract：:The seroprevalence of viral hepatitis in healthcare workers has important public health implications. To assess the risk factors for the acquisition of viral hepatitis in an unvaccinated cohort from an hyperendemic region, 567 healthcare workers from a large hospital in the capital of the Republic of Yemen were interv...

journal_title：Journal of medical virology

authors： Shidrawi R,Ali Al-Huraibi M,Ahmad Al-Haimi M,Dayton R,Murray-Lyon IM

更新日期：2004-08-01 00:00:00

abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:A serological survey for antibodies to hepatitis C virus (HCV), dengue viruses (DEN), West Nile virus (WN), and sindbis virus (SIN) was carried out in sera of selected groups of the population of the Islands of Mauritius (n = 449) and Rodrigues (n = 115), Indian Ocean. 8.3% of 564 sera were positive for anti-HCV. In M...

journal_title：Journal of medical virology

authors： Schwarz TF,Dobler G,Gilch S,Jäger G

更新日期：1994-12-01 00:00:00

abstract：:Epstein-Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosqu...

journal_title：Journal of medical virology

authors： Miyake T,Iwatsuki K,Hirai Y,Yamamoto T,Hamada T,Fujii K,Imamura H,Morizane S

更新日期：2020-04-07 00:00:00

abstract：:Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...

journal_title：Journal of medical virology

authors： Kobayashi M,Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Suzuki F,Akuta N,Someya T,Matsuda M,Sato J,Takagi K,Miyakawa Y,Kumada H

更新日期：2002-12-01 00:00:00