Hepatitis C and arboviral antibodies in the island populations of Mauritius and Rodrigues.

abstract：:We compared characteristics of patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA to those of patients with GBV-C/HGV E2-antibody. GBV-C/HGV RNA and GBV-C/HGV antibody were assayed in 83 persons with hemophilia using a reverse transcription-polymerase chain reaction and an enzyme-linked immunosorbent assay, re...

journal_title：Journal of medical virology

authors： Toyoda H,Takahashi I,Fukuda Y,Hayakawa T,Takamatsu J

更新日期：2000-01-01 00:00:00

abstract：:The presence of therapy-associated hepatitis B virus (HBV) variants is the main drawback of antiviral therapy for HBV infection. Moreover, drug-resistant variants are more insensitive to a second agent and more therapy-associated mutations will be present. To apply better nucleos(t)ide analogues (NA) and reduce the oc...

journal_title：Journal of medical virology

authors： Su F,Dai J,Yang S,Jiang X,Cui X,Ning H,Li J,Huang M

更新日期：2015-09-01 00:00:00

abstract：:Adhesion molecules are essential for the immune response. They are involved in the regulation of cell-to-cell contact, thereby enabling leukocytes to communicate. Circulating forms of adhesion molecules are found in the serum of healthy individuals. Raised levels have been associated with disease severity in HCV and o...

journal_title：Journal of medical virology

authors： Murgue B,Cassar O,Deparis X

更新日期：2001-09-01 00:00:00

abstract：:Although occult hepatitis B virus (HBV) infection in individuals without detectable hepatitis B surface antigen (HBsAg) may occur and has been reported to be common in patients with chronic hepatitis C, the related molecular mechanisms remain unknown. With the polymerase chain reaction, serum HBV DNA was sought in 100...

journal_title：Journal of medical virology

authors： Kao JH,Chen PJ,Lai MY,Chen DS

更新日期：2002-10-01 00:00:00

abstract：:In real-world settings, not much information is probably available on the treatment efficacy of the combination of glecaprevir and pibrentasvir (G/P) as a salvage therapy in failures of prior direct-acting antiviral (DAA) regimens. Especially, the evolution of NS5A resistance-associated variants (RAVs) and treatment e...

journal_title：Journal of medical virology

authors： Akuta N,Sezaki H,Suzuki F,Fujiyama S,Kawamura Y,Hosaka T,Kobayashi M,Kobayashi M,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kumada H

更新日期：2019-01-01 00:00:00

abstract：:Hemorrhagic fever with renal syndrome (HFRS) is a severe acute viral disease with pathological changes of impaired capillary and small vessels and thrombocytopenia. In this study, serum thrombospondin (TSP)-1 concentration in patients with HFRS was determined to explore its possible role in the pathogenesis of HFRS. T...

journal_title：Journal of medical virology

authors： Liu Z,Zhao Q,Han Q,Gao M,Zhang N

更新日期：2008-10-01 00:00:00

abstract：:Phylogenetic analysis was performed on hepatitis B virus (HBV) strains obtained from 86 hepatitis B surface antigen (HBsAg) positive donors from Thailand originating throughout the country. Based on the S gene, 87.5% of strains were of genotype C while 10.5% were of genotype B, with all genotype B strains obtained fro...

journal_title：Journal of medical virology

authors： Louisirirotchanakul S,Olinger CM,Arunkaewchaemsri P,Poovorawan Y,Kanoksinsombat C,Thongme C,Sa-Nguanmoo P,Krasae S,Theamboonlert A,Oota S,Fongsatitkul L,Puapairoj C,Promwong C,Weber B

更新日期：2012-10-01 00:00:00

abstract：:Mouse mammary tumor virus (MMTV) is a hormonally regulated, oncogenic virus of mice. MMTV-like virus DNA has previously been detected in human breast cancers, liver disease, and liver cancers. It is hypothesized that local hormonal effects might be of primary importance in determining MMTV-like virus detection in huma...

journal_title：Journal of medical virology

authors： Johal H,Faedo M,Faltas J,Lau A,Mousina R,Cozzi P,Defazio A,Rawlinson WD

更新日期：2010-05-01 00:00:00

abstract：:To determine risk factors responsible for primary cytomegalovirus (CMV) infection in Taiwan, samples of blood for antibody to CMV were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti-CMV IgG antibody. Logistic regression analysis showed that seropositivity correlated with age, met...

journal_title：Journal of medical virology

authors： Shen CY,Chang WW,Chang SF,Chao MF,Huang ES,Wu CW

更新日期：1992-05-01 00:00:00

abstract：:Rotavirus-specific subclass antibody responses and cytokines, tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-8 (IL-8), and IL-10, were measured in children 7-24 months of age with rotavirus diarrhoea (n = 29); the responses were compared with children with watery diarrhoea from who...

journal_title：Journal of medical virology

authors： Azim T,Zaki MH,Podder G,Sultana N,Salam MA,Rahman SM,Sefat-e-Khuda,Sack DA

更新日期：2003-02-01 00:00:00

abstract：:From 10(1) to 10(6) TCID50 (mean tissue culture infective doses) per ml HSV I and II can be quantitatively recorded from vaginal tampons. Tampons and sterile cotton swabs are equally sensitive in recovering HSV I and II. Direct cotton swab cultures of the cervix and cervicovaginal tampon cultures from the same patient...

journal_title：Journal of medical virology

authors： Ekwo EE,Myers MG

更新日期：1978-01-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：:Human hepatitis B virus (HBV) and hepatitis C virus (HCV) are two major etiologic agents of chronic hepatitis, which is closely related to the development of hepatocellular carcinoma (HCC). A possible involvement of HBV co-infection was investigated in ongoing HCV-related liver diseases in HCV-infected patients. A pre...

journal_title：Journal of medical virology

authors： Koike K,Kobayashi M,Gondo M,Hayashi I,Osuga T,Takada S

更新日期：1998-04-01 00:00:00

abstract：:The multiplication of HSV-1 and HSV-2 strains in the heart and the corresponding dorsal root ganglia (DRG) was examined in experimentally infected mice. Infectious HSV-1 was recovered from the heart between the second and fourth day after inoculation and 3 days later from the DRG. Both the heart and DRG yielded infect...

journal_title：Journal of medical virology

authors： Grodums EI,Kuling PJ,Zbitnew A

更新日期：1981-01-01 00:00:00

abstract：:We investigated the molecular epidemiology and biological characteristics of wild measles viruses isolated since 1984 in Japan. The circulating measles virus was of genotype C1 before 1985, D3 from 1987 to 1990, and D5 from 1990 to 1997. It was replaced by the same cluster of Chicago-type D3 strain from 1997 to 1999. ...

journal_title：Journal of medical virology

authors： Zhou J,Fujino M,Inou Y,Kumada A,Aoki Y,Iwata S,Nakayama T

更新日期：2003-08-01 00:00:00

abstract：:Predictive factors of HCV relapse after treatment with DAAs are poorly understood. In this study, we aimed to assess whether the residual viral load positivity observed during or at the end of treatment (EOT) has an impact on viral outcome. Blood samples were collected from 337 patients with genotypes (GT) 1a, 1b, 2, ...

journal_title：Journal of medical virology

authors： Visco-Comandini U,Lapa D,Lionetti R,Taibi C,Loiacono L,Montalbano M,Capobianchi MR,D'Offizi G,Garbuglia AR

更新日期：2018-07-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:Immunological factors, such as cytokines, have been proposed as a cause of changes in the lipid profile of dengue patients. We studied whether serum lipid levels and serum TNF-α levels are associated in a group of dengue patients from an endemic region in the Northwest of Mexico. We found statistically important diffe...

journal_title：Journal of medical virology

authors： Osuna-Ramos JF,Rendón-Aguilar H,Reyes-Ruiz JM,Del Ángel RM,Romero-Utrilla A,Ríos-Burgueño ER,Velarde-Rodriguez I,Velarde-Félix JS

更新日期：2018-06-01 00:00:00

abstract：:Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of I...

journal_title：Journal of medical virology

authors： Nishibe Y,Inoue YK,Melnick JL

更新日期：1986-10-01 00:00:00

abstract：:The relationship of pre-bone-marrow transplant recipient and donor cytomegalovirus (CMV) antibody level to post-transplant recipient CMV excretion was investigated. CMV excretion was found to be related to pre-transplant recipient serological status, but not to level of antibody. This therefore contrasts with herpes s...

journal_title：Journal of medical virology

authors： Pillay D,Webster A,Lee D,Prentice HG,Griffiths PD

更新日期：1991-04-01 00:00:00

abstract：:The X gene product of human hepatitis B virus, HBx, transactivates the expression of viral and cellular genes through a wide variety of cis elements, including the nuclear factor for IL-6 (NF-IL6) binding sites, although HBx does not appear to bind DNA directly. We previously reported that HBx transactivated the inter...

journal_title：Journal of medical virology

authors： Ohno H,Kaneko S,Lin Y,Kobayashi K,Murakami S

更新日期：1999-05-01 00:00:00

abstract：:Hepatitis E virus (HEV), a positive-strand RNA agent, has been associated with enterically transmitted non-A, non-B hepatitis in Asia, Africa, and Mexico. To evaluate the role of HEV in an outbreak of hepatitis in Pakistan, we used immune electron microscopy to detect 1) antibody to HEV, for evidence of infection, and...

journal_title：Journal of medical virology

authors： Ticehurst J,Popkin TJ,Bryan JP,Innis BL,Duncan JF,Ahmed A,Iqbal M,Malik I,Kapikian AZ,Legters LJ

更新日期：1992-02-01 00:00:00

abstract：:The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C virus (HCV) was analyzed in 13 interferon alpha (IFN-alpha) treated patients representing genotypes 1a, 1b, and 2b. These patients had previously been followed longitudinally during treatment with respect to viral load ...

journal_title：Journal of medical virology

authors： Odeberg J,Yun Z,Sönnerborg A,Weiland O,Lundeberg J

更新日期：1998-09-01 00:00:00

abstract：:An anti-hepatitis A virus (HAV)-specific immunoglobulin M capture enzyme-linked immunosorbent assay (anti-HAV IgM ELISA) kit was re-designed for laboratory use and compared with a commercial anti-HAV IgM detection system using 58 serum samples collected from patients, vaccines, and healthy individuals. Because concord...

journal_title：Journal of medical virology

authors： Kiyohara T,Ouchi Y,Hasegawa Y,Sato T,Yoneyama T,Ishii K,Ito T,Wakita T

更新日期：2009-09-01 00:00:00

abstract：:We have tested a multiplex polymerase chain reaction (PCR) human papillomavirus (HPV) genotyping assay to fill the need for rapid and low-cost HPV detection in Sub-Saharan Africa. This method allows high throughput genotyping and simultaneous detection of 14 high-risk and two low-risk HPV types, by PCR amplification o...

journal_title：Journal of medical virology

authors： Samwel K,Kahesa C,Mwaiselage J,Gonzalez D,West JT,Wood C,Palefsky J,Angeletti PC

更新日期：2019-02-01 00:00:00

abstract：:Enterovirus 71 H (E71 H), an isolate from an adult patient with hand-food-mouth disease (HFMD) in China, was serologically similar to the prototype strain E71 BrCr, which was isolated from a patient with aseptic meningitis. The study further analyzed the similarity of E71 H to E71 BrCr at the 5'-noncoding region (NCR)...

journal_title：Journal of medical virology

authors： Zheng ZM,He PJ,Caueffield D,Neumann M,Specter S,Baker CC,Bankowski MJ

更新日期：1995-10-01 00:00:00

abstract：:Hepatitis A infections still represent a major global health concern. During the past years, a transition pattern of the hepatitis A epidemiology was noted in many parts of the world. In Tunisia, there is not a recent survey on age-specific hepatitis A virus seroprevalence. This study aimed to investigate the seroprev...

journal_title：Journal of medical virology

authors： Ayouni K,Kharroubi G,Mallekh R,Hammami W,Marouani R,Mhamdi M,Ben Salah A,Triki H,Bettaieb J

更新日期：2020-09-28 00:00:00

abstract：:The ability of dengue virus-infected human monocyte-derived macrophages to induce permeability changes in primary human umbilical vein endothelial cells was investigated. Supernatants from dengue virus type 2-infected monocyte-derived macrophages increased permeability in human umbilical vein endothelial cell monolaye...

journal_title：Journal of medical virology

authors： Carr JM,Hocking H,Bunting K,Wright PJ,Davidson A,Gamble J,Burrell CJ,Li P

更新日期：2003-04-01 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:Deletions and insertions in the hepatitis B virus (HBV) X region have been associated with severe forms of liver disease, including hepatocellular carcinoma (HCC). However, the molecular epidemiologic features of this virus have been described rarely. Deletions and insertions in the X region were determined by direct ...

journal_title：Journal of medical virology

authors： Lee SA,Mun HS,Kim H,Lee HK,Kim BJ,Hwang ES,Kook YH,Kim BJ

更新日期：2011-01-01 00:00:00