Prevalence and types of drug-resistant variants in Chinese patients with acute hepatitis B.

abstract：:Mitochondrial DNA (mtDNA) of peripheral blood mononuclear cells (PBMCs) collected from Human immunodeficiency virus 1 (HIV-1)-infected patients and healthy controls were measured longitudinally using real-time polymerase chain reaction to evaluate the effects of antiretroviral agents on mtDNA synthesis in vivo and to ...

journal_title：Journal of medical virology

authors： Miura T,Goto M,Hosoya N,Odawara T,Kitamura Y,Nakamura T,Iwamoto A

更新日期：2003-08-01 00:00:00

abstract：:To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes in seropositive hemodialysis patients in Luanda. Among 51 HCV-positive subjects included, viremia was detected in 27 (53%). HCV genotyping was performed by bidir...

journal_title：Journal of medical virology

authors： da Costa Marques Borges LF,Zalis MG,Santoro-Lopes G,Varella RB

更新日期：2019-03-01 00:00:00

abstract：:To define better the human immune response to individual structural proteins of human cytomegalovirus (HCMV), 55 human sera with different IgG and IgM titres were studied for their reactivity with HCMV structural polypeptides separated by SDS-PAGE and electrotransferred to nitrocellulose paper. The results obtained sh...

journal_title：Journal of medical virology

authors： Landini MP,Re MC,Mirolo G,Baldassarri B,La Placa M

更新日期：1985-12-01 00:00:00

abstract：:Guinea pigs infected with Argentine hemorrhagic fever virus (Junin) were treated with pooled, homologous convalescent sera. Use of 15,000 or 5,000 therapeutic units of immune sera prevented all signs of illness when administered within 24 hr of infection. We could also prevent illness and death in infected guinea pigs...

journal_title：Journal of medical virology

authors： Kenyon RH,Green DE,Eddy GA,Peters CJ

更新日期：1986-11-01 00:00:00

abstract：:An outbreak of an acute sporadic viral hepatitis occurring at three villages in the lower Shebli region of southern Somalia was studied. Sera were examined for antibodies to hepatitis E virus (HEV) antigen by a recently developed enzyme-linked immunosorbent assay. The prevalence of anti-HEV ranged from 77.8% to 94.0% ...

journal_title：Journal of medical virology

authors： Mushahwar IK,Dawson GJ,Bile KM,Magnius LO

更新日期：1993-07-01 00:00:00

abstract：:Parechoviruses are emerging pathogens of humans often affecting the pediatric age group, with a growing line of evidence implicating them as agents of a broad spectrum of clinical syndromes in adults. However, because many clinicians are not familiar with the manifestation of the infections, they are not included in t...

journal_title：Journal of medical virology

authors： Kabuga AI,Nejati A,Soheili P,Shahmahmoodi S

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a single-stranded RNA virus related to the Flaviviridae family, and striking nucleotide sequence diversity has been reported among HCV isolates from different geographic areas. To study the distribution HCV genotypes among disease group in Korea, we subtyped HCV using the method of Okamoto e...

journal_title：Journal of medical virology

authors： Lee DS,Sung YC,Whang YS

更新日期：1996-05-01 00:00:00

abstract：:Because in situ/filter hybridisation is not sensitive enough and because classical polymerase chain reaction (PCR) protocols are generally not sufficiently reproducible and specific, there is little accurate information on the prevalence of human papillomaviruses (HPV) 16, 18, and 33 infections in women without dyskar...

journal_title：Journal of medical virology

authors： Vandenvelde C,Scheen R,Van Pachterbeke C,Loriaux C,Decelle J,Hubert T,Delhaye C,Cattoor JP,Duys M,Van Beers D

更新日期：1992-04-01 00:00:00

abstract：:The presence of HPV 16 E6*I/E6*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The detection of HPV 16 E6*I/E6*II mRNAs w...

journal_title：Journal of medical virology

authors： Cricca M,Venturoli S,Leo E,Costa S,Musiani M,Zerbini M

更新日期：2009-07-01 00:00:00

abstract：:Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned to possess several a...

journal_title：Journal of medical virology

authors： Sadaie MR,Zamani M,Whang S,Sistron N,Arya SK

更新日期：1998-02-01 00:00:00

abstract：:The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of immunologic and molecular based assays. Genotyping studies show that the genetic diversity of HBV is very high even in industrialized countries. The analytical sensitivity of HBsAg and anti-HBs assays may be dependent on H...

journal_title：Journal of medical virology

authors： Weber B

更新日期：2006-01-01 00:00:00

abstract：:The increased immigration from developing regions to Western countries raises public health concerns related to blood-borne viruses. The prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-lymphotropic virus (HTLV) infections among recent immigrants attending...

journal_title：Journal of medical virology

authors： Toro C,Jiménez V,Rodríguez C,Del Romero J,Rodés B,Holguín A,Alvarez P,García-Campello M,Gómez-Hernando C,Guelar A,Sheldon J,de Mendoza C,Simón A,Soriano V

更新日期：2006-12-01 00:00:00

abstract：:The prevalence study and the characterization of hepatitis C virus (HCV) was carried out in the Philippines and the sequence determination of the 5'-untranslated region (5'-UTR)-Core and the NS5B regions of HCV was carried out in this study. An HCV strain (SE-03-07-1689) collected in Metro Manila, Philippines, belonge...

journal_title：Journal of medical virology

authors： Kageyama S,Agdamag DM,Alesna ET,Leaño PS,Heredia AM,Abellanosa-Tac-An IP,Jereza LD,Tanimoto T,Yamamura J,Ichimura H

更新日期：2006-11-01 00:00:00

abstract：:Elevated telomerase activity is observed in about 90% of human cancers. This activity correlates strictly with human telomerase reverse transcriptase (hTERT). Previously, it was shown that the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induced telomerase activity in nasopharyngeal carcinoma cells. In ...

journal_title：Journal of medical virology

authors： Ding L,Li L,Yang J,Zhou S,Li W,Tang M,Shi Y,Yi W,Cao Y

更新日期：2007-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) represents a major cause of posttransfusion hepatitis worldwide. Posttransfusion hepatitis associated with hepatitis B virus (HBV) continues to occur. HBsAg-negative donor sera from the Rhode Island Blood Center between 1987 and 1988 were screened using more sensitive techniques to assess the p...

journal_title：Journal of medical virology

authors： Liang TJ,Bodenheimer HC Jr,Yankee R,Brown NV,Chang K,Huang J,Wands JR

更新日期：1994-02-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:The genotypic inhibitory quotient (GIQ) is the ratio between drug concentration and the number of resistance mutations. However, as different resistance scores can be calculated for the same protease inhibitor, the ability of a GIQ to predict the virological outcome may vary depending on the resistance score used as t...

journal_title：Journal of medical virology

authors： Gianotti N,Galli L,Danise A,Hasson H,Boeri E,Lazzarin A,Castagna A

更新日期：2006-12-01 00:00:00

abstract：:GB virus C/hepatitis G virus (GBV-C/HGV) is related distantly to hepatitis C virus (HCV). HCV has a hypervariable region (HVR), and exists as quasispecies in vivo. Although GBV-C/HGV also has replaceable amino acids in the presumed antigenic region, the existence and fluctuation of population of heterogeneous virus ha...

journal_title：Journal of medical virology

authors： Kato T,Mizokami M,Nakano T,Orito E,Ohba K,Kondo Y,Tanaka Y,Ueda R,Mukaide M,Fujita K,Yasuda K,Iino S

更新日期：1998-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosqu...

journal_title：Journal of medical virology

authors： Miyake T,Iwatsuki K,Hirai Y,Yamamoto T,Hamada T,Fujii K,Imamura H,Morizane S

更新日期：2020-04-07 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：:The prevalence of HHV-8 infection varies widely in South American populations, displaying geographical variations in its distribution. The heterogeneous genetic contributions provided by the transatlantic parental populations that modified the Native American genomes may explain this epidemiological observation. Aimin...

journal_title：Journal of medical virology

authors： Hulaniuk ML,Torres O,Bartoli S,Fortuny L,Burgos Pratx L,Nuñez F,Salamone H,Corach D,Trinks J,Caputo M

更新日期：2017-03-01 00:00:00

abstract：:In patients infected with the hepatitis C virus (HCV), a heterogeneous population of viruses, so-called quasispecies exists in vivo. The hypervariable regions (HVR) within the second envelope gene (HCV-E2) show particularly highly intratypic variability and are considered to be the target of neutralizing antibodies. T...

journal_title：Journal of medical virology

authors： Lee JH,Stripf T,Roth WK,Zeuzem S

更新日期：1997-11-01 00:00:00

abstract：:Stored demographic data and HIV RT and protease sequences of 877 HIV patients attending for the first time the HIV/AIDS outpatient clinics of a reference Infectious Diseases centre in Northern Italy between 1999 and 2006 were stratified by 3-year spanning periods according to date of HIV infection. In the period 1980-...

journal_title：Journal of medical virology

authors： Baldanti F,Paolucci S,Ravasi G,Maccabruni A,Moriggia A,Barbarini G,Maserati R

更新日期：2008-06-01 00:00:00

abstract：:Recently a conventional method for the laboratory diagnosis of human cytomegalovirus (HCMV) infection was improved by using centrifugation culture to enhance viral adsorption and by detecting HCMV early antigen and DNA. Comparison of the sensitivity of three rapid methods using commercial diagnostic reagents for the d...

journal_title：Journal of medical virology

authors： Li SB,Fong CK

更新日期：1990-02-01 00:00:00

abstract：:The importance of hepatitis B virus (HBV) genotypes for disease progression and response to interferon-alpha-based treatment is well established. While almost all patients in the Mediterranean area are infected with HBV genotype D, HBV genotype A is dominant in Northern Europe. However, the distribution of HBV genotyp...

journal_title：Journal of medical virology

authors： Deterding K,Constantinescu I,Nedelcu FD,Gervain J,Nemecek V,Srtunecky O,Vince A,Grgurevic I,Bielawski KP,Zalewska M,Bock T,Ambrozaitis A,Stanczak J,Takács M,Chulanov V,Slusarczyk J,Drazd'áková M,Wiegand J,Cornberg M,

更新日期：2008-10-01 00:00:00

abstract：:The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the extracellular environment. Hsp70 and antibodies against Hsp70 have been reported in human serum. Recent evidence has shown that Hsp70 antibodies are elevated in HIV in...

journal_title：Journal of medical virology

authors： Papp D,Prohászka Z,Kocsis J,Füst G,Bánhegyi D,Raynes DA,Guerriero V

更新日期：2005-08-01 00:00:00

abstract：:Herpes simplex virus can be quantitatively recovered from vaginal tampons suspended in tissue culture medium and stored over a wide range of temperatures. Because herpes simplex virus is stable for several days with refrigeration or after freezing, this method of culture of cervicovaginal virus lends itself to epidemi...

journal_title：Journal of medical virology

authors： Myers MG,Ekwo EE,Pitts AK

更新日期：1979-01-01 00:00:00

abstract：:The ability to detect type-specific high risk HPV (HR-HPV) infections in samples from females and males is important for monitoring the epidemiology of HPV and the impact of vaccination. Type-specific detection concordance between paired urine and genital samples from females (n = 264) undergoing routine colposcopy an...

journal_title：Journal of medical virology

authors： Bissett SL,Howell-Jones R,Swift C,De Silva N,Biscornet L,Parry JV,Saunders NA,Nathan M,Soldan K,Szarewski A,Cuzick J,Beddows S

更新日期：2011-10-01 00:00:00

abstract：:Noroviruses (NoVs) are a leading cause of acute gastroenteritis outbreaks and sporadic cases of diarrhea in industrialized countries. To study the prevalence and genetic diversity of NoVs in Guatemala, stool specimens were collected from hospitalized and ambulatory patients presenting with diarrhea (≥3 loose or liquid...

journal_title：Journal of medical virology

authors： Estévez A,Arvelo W,Hall AJ,López MR,López B,Reyes L,Moir JC,Gregoricus N,Vinjé J,Parashar UD,Lindblade KA

更新日期：2013-07-01 00:00:00