Treatment of junin virus-infected guinea pigs with immune serum: development of late neurological disease.

abstract：:Hepatitis B virus (HBV) infection is a dynamic process during which molecular variants are selected continuously to adapt to changes. In addition to drug resistant mutations, sequential antiviral therapy may also lead to the selection of deleted mutants. To investigate this process, the following samples were collecte...

journal_title：Journal of medical virology

authors： Ji F,Zhou L,Ma S,Li F,Ding H,Zeng C

更新日期：2009-09-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

journal_title：Journal of medical virology

authors： Ren L,Xiao Q,Zhou L,Xia Q,Liu E

更新日期：2015-01-01 00:00:00

abstract：:Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotides within the context of certain flanking bases (CpG motifs) have been shown to induce potent innate and adaptive immune responses. Vaginal delivery of CpG ODN alone protects mice from vaginal herpes simplex virus type-2 (HSV-2) challenge. He...

journal_title：Journal of medical virology

authors： Sajic D,Ashkar AA,Patrick AJ,McCluskie MJ,Davis HL,Levine KL,Holl R,Rosenthal KL

更新日期：2003-12-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection is considered a neglected disease of major concern in developed countries. Clinically, HEV occurs as an acute and self-limited disease, though chronic cases mostly associated to HEV-3 are now being commonly reported in immunocompromised individuals and solid organ transplant recipient...

journal_title：Journal of medical virology

authors： Bangueses F,Abin-Carriquiry JA,Cancela F,Curbelo J,Mirazo S

更新日期：2020-06-27 00:00:00

abstract：:The kinetics of hepatitis B virus (HBV) and its surface antigen (HBsAg) during acute hepatitis has not yet been studied accurately in a representative number of patients. The influence of coinfecting hepatitis viruses during the acute phase of infection is not known. Three to four serum samples from 21 patients with a...

journal_title：Journal of medical virology

authors： Chulanov VP,Shipulin GA,Schaefer S,Gerlich WH

更新日期：2003-03-01 00:00:00

abstract：:This study was designed to determine the prognostic value of erythrocyte adenosine deaminase (ADA) as a possible indicator of progression to AIDS, and compare this with other known cellular and serological markers. At the end of a 3-year study, a cohort of 114 human immunodeficiency virus-1 (HIV-1) seropositive intrav...

journal_title：Journal of medical virology

authors： Casoli C,Lisa A,Magnani G,Starcich R,Fiaccadori F,Bertazzoni U,Zei G

更新日期：1995-02-01 00:00:00

abstract：:Sera of patients from China with hepatocellular carcinoma (HCC) were tested for the presence of HBc/HBe- and HBx antibodies by immunoblotting using recombinant MS2 or beta gal fusion proteins as substrate. Antibodies against HBx were detected in four out of 68 HBsAg positive and in one out of three HBsAg negative sera...

journal_title：Journal of medical virology

authors： Liang XH,Stemler M,Will H,Braun R,Tang ZY,Schröder CH

更新日期：1988-07-01 00:00:00

abstract：:In vitro, beta-herpesviruses can stimulate or inhibit HIV replication under particular circumstances. In order to investigate the effects of beta-herpesvirus infection on HIV replication and vice versa at an organ level, we determined the quantitative relationships between cytomegalovirus (CMV), human herpesviruses (H...

journal_title：Journal of medical virology

authors： Emery VC,Atkins MC,Bowen EF,Clark DA,Johnson MA,Kidd IM,McLaughlin JE,Phillips AN,Strappe PM,Griffiths PD

更新日期：1999-03-01 00:00:00

abstract：:Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analog...

journal_title：Journal of medical virology

authors： Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV

更新日期：2015-06-01 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of hepatitis B e antigen (HBeAg) negative/treatment naïve subjects with low hepatitis B virus (HBV) DNA levels (<10(4)  copies/ml) and low alanine aminotransferase (ALT) levels (<2 × upper limit of normal) in patients with HBV-related hepatocellular carcinoma (HCC)....

journal_title：Journal of medical virology

authors： Zeng DW,Dong J,Zhang JM,Zhu YY,Jiang JJ,Liu YR

更新日期：2015-10-01 00:00:00

abstract：:Molecular investigation was undertaken of circulating hepatitis A virus (HAV) associated with cases of acute diarrhea among children under 5 years of age in Kumba-Cameroon. Reverse transcription PCR, sequencing, and phylogenetic analysis of a 371 bp segment of the VP1/P2A junction of six isolates obtained from stool s...

journal_title：Journal of medical virology

authors： Forbi JC,Agwale SM,Ndip LM,Esona MD

更新日期：2012-05-01 00:00:00

abstract：:Interaction between herpesviruses and human immunodeficiency virus (HIV)1 is postulated in the progression of HIV disease. In order to evaluate the specific antibody responses directed to Epstein-Barr virus (EBV) and cytomegalovirus (CMV) and to provide serological evidence suggesting reactivation of these viruses abl...

journal_title：Journal of medical virology

authors： Quesnel A,Pozzetto B,Touraine F,Moja P,Lucht F,De The G,Touraine JL,Gaudin O,Genin C

更新日期：1992-01-01 00:00:00

abstract：:A total of 18 rotavirus G9 strains in South Korea were collected during five rotavirus seasons between 2005 and 2010. The relationship between these strains was examined by analyzing the genetic variation of two major structural genes, VP7 and VP4. All the rotavirus isolates were of the G9P[8] genotype. The VP7 phylog...

journal_title：Journal of medical virology

authors： Than VT,Kang H,Lim I,Kim W

更新日期：2013-01-01 00:00:00

abstract：:Occult hepatitis C virus (HCV) infection is characterized by the presence of HCV RNA in the liver cells or peripheral blood mononuclear cells of the patients whose serum samples test negative for HCV RNA, with or without presence of HCV antibodies. The present study reviews the existing literature on the persistence o...

journal_title：Journal of medical virology

authors： Vidimliski PD,Nikolov I,Geshkovska NM,Dimovski A,Rostaing L,Sikole A

更新日期：2014-09-01 00:00:00

abstract：:In April 2004, two patients were admitted to hospital in Berlin, Germany, with clinical signs of acute respiratory infection after returning from a military exercise in their home country of Turkey. They were admitted to a high security infectious disease unit as epidemiological data pointed to an outbreak of unknown ...

journal_title：Journal of medical virology

authors： Chmielewicz B,Benzler J,Pauli G,Krause G,Bergmann F,Schweiger B

更新日期：2005-10-01 00:00:00

abstract：:Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned to possess several a...

journal_title：Journal of medical virology

authors： Sadaie MR,Zamani M,Whang S,Sistron N,Arya SK

更新日期：1998-02-01 00:00:00

abstract：:The immunogenicity of the Russian cold-adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60-ca, were compared in BALB/c mice with their respective wild-type parental viruses. Each ca donor strain was less immunogenic than its wild-type parent. The va...

journal_title：Journal of medical virology

authors： Wareing MD,Watson JM,Brooks MJ,Tannock GA

更新日期：2001-09-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Puumala and Tula viruses are hantaviruses found in Europe and are associated with the rodents Clethrionomys glareolus and Microtus arvalis, respectively. Puumala virus is associated with the human disease nephropathia epidemica. In Austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by...

journal_title：Journal of medical virology

authors： Bowen MD,Gelbmann W,Ksiazek TG,Nichol ST,Nowotny N

更新日期：1997-10-01 00:00:00

abstract：:Exacerbations of chronic hepatitis B have been associated with accumulation of mutations in the HBV core gene, with amino acid (aa) substitutions clustering between aa 50 and 69. This region of the nucleocapsid protein is known as an immunodominant epitope for CD4+ T-lymphocytes, however the impact of these mutations ...

journal_title：Journal of medical virology

authors： Torre F,Cramp M,Owsianka A,Dornan E,Marsden H,Carman W,Williams R,Naoumov NV

更新日期：2004-03-01 00:00:00

abstract：:In October 1977 an outbreak of acute infectious diarrhea occurred in an infant home in the city of Sapporo, Japan. Of 34 residents aged two to 20 months, 26 (77%) suffered from diarrhea. In ten of these patients the diarrhea was accompanied by vomiting. Electron microscopic examinations revealed typical calicivirus pa...

journal_title：Journal of medical virology

authors： Chiba S,Sakuma Y,Kogasaka R,Akihara M,Horino K,Nakao T,Fukui S

更新日期：1979-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV) serology continues to be the first diagnostic test when infectious mononucleosis is suspected. Due to possible mild immunosuppression in competitive athletes, EBV reactivation determined by increases in salivary viral load have been identified as one possible cause in recurrent respiratory inf...

journal_title：Journal of medical virology

authors： Pottgiesser T,Schumacher YO,Wolfarth B,Schmidt-Trucksäss A,Bauer G

更新日期：2012-09-01 00:00:00

abstract：:Five temperature-sensitive mutants (tsm9, tsm13, tsm20, tsm22, tsm30) of murine cytomegalovirus have been shown previously not to produce infectious virus in mice. In the present study, the stage at which these mutants are blocked in their replication in vitro was examined by transcriptional analysis of 4 temporally r...

journal_title：Journal of medical virology

authors： Gill TA,Morley PJ,Sweet C

更新日期：2000-10-01 00:00:00

abstract：:The live varicella vaccine has been recommended for use in immunocompromised subjects and in adults who are susceptible to chickenpox. However, we do not know how humoral and cell-mediated immune responses induced after vaccination differed from those obtained after natural infection. To answer this, 45 previously inf...

journal_title：Journal of medical virology

authors： Ndumbe PM,Cradock-Watson J,Levinsky RJ

更新日期：1988-06-01 00:00:00

abstract：:Throughout most of the last decade, B/Yamagata/16/88-lineage influenza viruses were predominant among the B isolates circulating worldwide, whereas B/Victoria/2/87-lineage viruses were isolated infrequently and restricted geographically to eastern Asia. During the 2001-02 influenza season, B/Victoria/2/87-lineage viru...

journal_title：Journal of medical virology

authors： Puzelli S,Frezza F,Fabiani C,Ansaldi F,Campitelli L,Lin YP,Gregory V,Bennett M,D'Agaro P,Campello C,Crovari P,Hay A,Donatelli I

更新日期：2004-12-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in December 2019 and was basically under control in April 2020 in Wuhan. To explore the impact of intervention measures on the COVID-19 epidemic, we established susceptible-exposed-infectious-r...

journal_title：Journal of medical virology

authors： Li M,Guo X,Wang X

更新日期：2021-01-07 00:00:00

abstract：:Strains of human coronavirus (HCV) isolated between 1974 and 1976 have been studied in vitro and in volunteers. All strains caused colds in volunteers, and those cultivable in tissue culture (TC) produced significantly more coryza and less sore throat than strains growing only in organ culture (OC). The TC strains wer...

journal_title：Journal of medical virology

authors： Reed SE

更新日期：1984-01-01 00:00:00

abstract：:The complete VP1 protein of EV71 was truncated into six segments and fused to the C-terminal ends of full-length nucleocapsid protein (NPfl) and truncated NP (NPt; lacks 20% amino acid residues from its C-terminal end) of newcastle disease virus (NDV). Western blot analysis using anti-VP1 rabbit serum showed that the ...

journal_title：Journal of medical virology

authors： Sivasamugham LA,Cardosa MJ,Tan WS,Yusoff K

更新日期：2006-08-01 00:00:00

abstract：:Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

journal_title：Journal of medical virology

authors： Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

更新日期：2001-10-01 00:00:00

abstract：:Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, we examined sera from patients and controls for anti...

journal_title：Journal of medical virology

authors： Cukor G,Blacklow NR,Braverman LE

更新日期：1982-01-01 00:00:00