Direct evidence that naturally occurring mutations within hepatitis B core epitope alter CD4+ T-cell reactivity.

abstract：:Human bocavirus (HBOV) has been reported as a worldwide distributed respiratory pathogen. It has also been associated with encephalitis recently by detection of the virus in cerebrospinal fluid (CSF) of patients presented with encephalitis. This retrospective study aimed to present clinical features of HBOV infections...

journal_title：Journal of medical virology

authors： Akturk H,Sık G,Salman N,Sutcu M,Tatli B,Ciblak MA,Erol OB,Torun SH,Citak A,Somer A

更新日期：2015-11-01 00:00:00

abstract：:BK polyomavirus (BKV) is a ubiquitous virus in humans that remains latent in the urogenital tract after a primary infection during childhood. The virus, which is reactivated frequently and excreted in urine, can cause nephropathy in renal transplant recipients. BKV sequences are classified into four subtypes (I-IV). S...

journal_title：Journal of medical virology

authors： Boukoum H,Nahdi I,Foulongne V,Zallema D,Aloui S,Achour A,Segondy M,Aouni M

更新日期：2011-04-01 00:00:00

abstract：:Human metapneumovirus, with two known genotypes named A and B, is associated with mild respiratory symptoms to severe LRTI in children, high-risk adults and the elderly. Rapid and reliable methods of hMPV detection in clinical samples are essential to implement appropriate care, to better understand the pathology of h...

journal_title：Journal of medical virology

authors： Manoha C,Bour JB,Pitoiset C,Darniot M,Aho S,Pothier P

更新日期：2008-01-01 00:00:00

abstract：:Algeria is the largest country of Africa, peopled with populations living a range of traditional/rural and modern/urban lifestyles. The variations of prevalence of chronic active hepatitis care poorly known on the Algerian territory. We conducted a retrospective survey on all patients (n = 998) referred to our institu...

journal_title：Journal of medical virology

authors： Bensalem A,Selmani K,Hihi N,Bencherifa N,Mostefaoui F,Kerioui C,Pineau P,Debzi N,Berkane S

更新日期：2016-08-01 00:00:00

abstract：:Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...

journal_title：Journal of medical virology

authors： Druce J,Tran T,Kelly H,Kaye M,Chibo D,Kostecki R,Amiri A,Catton M,Birch C

更新日期：2005-01-01 00:00:00

abstract：:The nucleotide sequence of 10 isolates of human parvovirus B19 (B19) were determined and compared throughout 96.3% of the open reading frames (4145 nucleotides from nt. 509-4653). In the 4145 nucleotides, 122 mutation sites were found, of which 24 were accompanied by amino acid displacement. Furthermore, the polymorph...

journal_title：Journal of medical virology

authors： Fukada K,Matumoto K,Takakura F,Yamaki M,Sato H,Okochi K,Maeda Y

更新日期：2000-09-01 00:00:00

abstract：:The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented and explosive epidemics in India and the Indian Ocean islands after a gap of 32 years is a major public health concern. Currently, there is no specific therapy available to treat CHIKV infection. In the present study, the in vitro prophylactic an...

journal_title：Journal of medical virology

authors： Khan M,Santhosh SR,Tiwari M,Lakshmana Rao PV,Parida M

更新日期：2010-05-01 00:00:00

abstract：:human diploid fibroblasts and human primary liver cell carcinoma cells (PLC/PRF/5) were infected with hepatitis A virus (HAV) adapted to growth in cell culture or derived directly from human stool. Viral antigen was expressed in PLC/PRF/5 cells 28 days after infection with cell culture-adapted HAV, and 50 days after i...

journal_title：Journal of medical virology

authors： Gauss-Müller V,Frösner GG,Deinhardt F

更新日期：1981-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignant tumor. Recently, cidofovir, an anti-viral drug which is an acyclic nucleoside analogue, has been reported to have an anti-tumor potential. Two patients with NPC, who had previously received multi-round therapy, were treated with cidofov...

journal_title：Journal of medical virology

authors： Yoshizaki T,Wakisaka N,Kondo S,Murono S,Shimizu Y,Nakashima M,Tsuji A,Furukawa M

更新日期：2008-05-01 00:00:00

abstract：:The various strains of human polyomavirus BK (BKV) show a marked heterogeneity in the non-coding control region (NCCR), which includes the origin of replication and the regulatory region for early and late transcription. A new BKV strain (DDP, U91605) was identified by direct detection and sequencing of PCR products o...

journal_title：Journal of medical virology

authors： Degener AM,Pietropaolo V,Di Taranto C,Jin L,Ameglio F,Cordiali-Fei P,Trento E,Sinibaldi L,Orsi N

更新日期：1999-08-01 00:00:00

abstract：:The influence of an acute Epstein-Barr virus (EBV) infection on the serological parameters of persistent varicella-zoster virus (VZV) and herpes simplex virus (HSV) was studied. Sera from 161 patients with infectious mononucleosis caused by EBV and 178 age-matched controls were tested for HSV- and VZV-specific IgA. 98...

journal_title：Journal of medical virology

authors： Karner W,Bauer G

更新日期：1994-11-01 00:00:00

abstract：:To determine the influence of ageing per se as well as of priming histories on the antibody response to influenza vaccination, haemagglutination inhibition (HI), ELISA IgG, IgA, IgM and neutralizing antibody titres were studied in 43 healthy young subjects (mean age 23 years) and 55 healthy elderly people (mean age 79...

journal_title：Journal of medical virology

authors： Remarque EJ,de Bruijn IA,Boersma WJ,Masurel N,Ligthart GJ

更新日期：1998-05-01 00:00:00

abstract：:Human papillomavirus (HPV) is known to be the cause of almost all cervical cancers. The genotypes have been classified into high and low risk types according to their oncogenic potential. However, data for many of the genotypes are limited and some (HPV-26, 53, and 66) have no agreed status. A study was undertaken to ...

journal_title：Journal of medical virology

authors： Brestovac B,Harnett GB,Smith DW,Shellam GR,Frost FA

更新日期：2005-05-01 00:00:00

abstract：:The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is not clear if residual plasma HIVs during HAART can become predominant...

journal_title：Journal of medical virology

authors： Sahu GK,Paar D,Frost SD,Smith MM,Weaver S,Cloyd MW

更新日期：2009-01-01 00:00:00

abstract：:The use of new Direct Acting Antivirals, specific of HCV, has greatly improved the HCV treatment. Most of the DAA are specific of HCV genotypes. Genotyping methods may target different regions of the HCV genome, though only the whole genome sequencing could confirm the correct genotype. The present study describes the...

journal_title：Journal of medical virology

authors： Mourez T,Decroos A,Goria O,Montialoux H,De Oliveira F,Larrat S,Plantier JC,Riachi G

更新日期：2018-05-01 00:00:00

abstract：:Primary infection, seroconversion, and transmitted drug resistance (TDR) during pregnancy may influence the risk of mother-to-child-transmission (MTCT) of HIV-1 infection. This study estimated recent seroconversion, TDR rates, HIV-1 subtypes and pregnancy outcomes among 95 recently diagnosed, antiretroviral (ARV)-naïv...

journal_title：Journal of medical virology

authors： Lima YA,Cardoso LP,Reis MN,Stefani MM

更新日期：2016-11-01 00:00:00

abstract：:Immunocompromised individuals were tested for the presence of the human polyomaviruses JC (JCV) and BK (BKV) by the polymerase chain reaction (PCR). The use of appropriate primers in a nested PCR allowed the detection of both viruses simultaneously. Viruses were differentiated by restriction fragment length analysis o...

journal_title：Journal of medical virology

authors： Schätzl HM,Sieger E,Jäger G,Nitschko H,Bader L,Ruckdeschel G,Jäger G

更新日期：1994-02-01 00:00:00

abstract：:Maternal injection drug use and peripheral blood mononuclear cell infection by hepatitis C virus are important risk factors for perinatal transmission of the virus. The aim of present study was to evaluate the independent association of these two factors on perinatal transmission. Forty-eight consecutive mothers who t...

journal_title：Journal of medical virology

authors： Azzari C,Moriondo M,Indolfi G,Betti L,Gambineri E,de Martino M,Resti M

更新日期：2008-01-01 00:00:00

abstract：:Anti-influenza serum and nasal antibody titers were followed during a double-blind, placebo-controlled, randomized study assessing the prophylactic efficacy of 50, 100, and 200 mg/day of amantadine hydrochloride against experimental challenge with influenza A/Beth/1/85. The geometric mean titers (GMT) of serum hemaggl...

journal_title：Journal of medical virology

authors： Reuman PD,Bernstein DI,Keely SP,Young EC,Sherwood JR,Schiff GM

更新日期：1989-02-01 00:00:00

abstract：:Healthcare-associated infections with hepatitis C virus (HCV) hitherto have been observed mainly in hemodialysis settings as well as in hematology and oncology wards. In this communication, molecular and epidemiologic investigations to elucidate an HCV outbreak in an orthopedic ward are reported. One hundred and thirt...

journal_title：Journal of medical virology

authors： Ross RS,Viazov S,Khudyakov YE,Xia GL,Lin Y,Holzmann H,Sebesta C,Roggendorf M,Janata O

更新日期：2009-02-01 00:00:00

abstract：:It have been suggested that hepatitis B virus (HBV) pre-S deletions may play a role in hepatocarcinogenesis. The aim of the study was to determine the prevalence of pre-S deletions in chronic hepatitis B patients in Hong Kong, the factors associated with the deletions and its relationship with hepatitis B e antigen (H...

journal_title：Journal of medical virology

authors： Yeung P,Wong DK,Lai CL,Fung J,Seto WK,Yuen MF

更新日期：2010-11-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) play a central role in tumor invasion and metastasis. Increased expression of MMPs occurs during development of hepatocellular carcinoma (HCC) in humans following infection with hepatitis B virus (HBV). Woodchucks are used as an animal model for hepadnavirus-induced HCC. All woodchucks...

journal_title：Journal of medical virology

authors： Ochoa-Callejero L,Toshkov I,Menne S,Martínez A

更新日期：2013-07-01 00:00:00

abstract：:Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

journal_title：Journal of medical virology

authors： Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

更新日期：2006-05-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...

journal_title：Journal of medical virology

authors： Newbound GC,O'Rourke JP,Collins ND,Andrews JM,DeWille J,Lairmore MD

更新日期：2000-10-01 00:00:00

abstract：:This was an exploratory study to investigate lamivudine-resistant hepatitis B virus (HBV) strains in selected lamivudine-naïve HBV carriers with and without human immunodeficiency virus (HIV) co-infection in South African patients. Thirty-five lamivudine-naïve HBV infected patients with or without HIV co-infection wer...

journal_title：Journal of medical virology

authors： Selabe SG,Lukhwareni A,Song E,Leeuw YG,Burnett RJ,Mphahlele MJ

更新日期：2007-11-01 00:00:00

abstract：:This study aimed to examine the application of hepatitis B surface antigen (HBsAg) confirmatory testing when diagnosing hepatitis B infection among young persons in Taiwan with a low prevalence rate of hepatitis B infection. HBsAg status, the presence of antibodies against HBsAg (anti-HBs), and the presence of antibod...

journal_title：Journal of medical virology

authors： Chu FY,Su FH,Cheng SH,Lin YS,Li CY,Chien CC,Lin YC,Chiang SY

更新日期：2011-09-01 00:00:00

abstract：:In order to assess the efficacy of interferon-alpha on hepatitis C viral RNA in patients with chronic hepatitis C, we analyzed the levels of HCV RNA in sera and liver tissues of 16 patients pre- and posttreatment using a semiquantitative polymerase chain reaction method. Fifteen of 16 patients were positive for anti-H...

journal_title：Journal of medical virology

authors： Liang TJ,Rustgi V,Galun E,Blum HE

更新日期：1993-05-01 00:00:00

abstract：:The ability to detect type-specific high risk HPV (HR-HPV) infections in samples from females and males is important for monitoring the epidemiology of HPV and the impact of vaccination. Type-specific detection concordance between paired urine and genital samples from females (n = 264) undergoing routine colposcopy an...

journal_title：Journal of medical virology

authors： Bissett SL,Howell-Jones R,Swift C,De Silva N,Biscornet L,Parry JV,Saunders NA,Nathan M,Soldan K,Szarewski A,Cuzick J,Beddows S

更新日期：2011-10-01 00:00:00

abstract：:Noroviruses (called formerly "Norwalk-like viruses") cause food-borne gastroenteritis outbreaks. These outbreaks were thought to be related to shellfish consumption, although non-shellfish related outbreaks also occurred frequently in Japan. To clarify the epidemiology of Norovirus outbreaks, 435 stool samples were co...

journal_title：Journal of medical virology

authors： Hamano M,Kuzuya M,Fujii R,Ogura H,Yamada M

更新日期：2005-10-01 00:00:00

abstract：:Self-limited involvement of the central nervous system (CNS) is a relatively common complication of primary infection with human herpesvirus six (HHV-6) in normal children. We describe an HIV-infected infant who developed fulminant encephalitis as a complication of HHV-6 infection. Immunohistochemical staining of CNS ...

journal_title：Journal of medical virology

authors： Knox KK,Harrington DP,Carrigan DR

更新日期：1995-03-01 00:00:00