Depletion of mitochondrial DNA in HIV-1-infected patients and its amelioration by antiretroviral therapy.

abstract：:The human papillomavirus (HPV) 16 genome has been studied extensively, although no study has focused on the E1 gene that is implicated in viral DNA replication. After analyzing the E1 region of HPV 16 genomes in 429 cervical samples, 11.2% were found to contain a 63 nucleotides duplication in this region. Sequence ana...

journal_title：Journal of medical virology

authors： Sabol I,Matovina M,Gasperov NM,Grce M

更新日期：2008-12-01 00:00:00

abstract：:Exacerbations of chronic hepatitis B have been associated with accumulation of mutations in the HBV core gene, with amino acid (aa) substitutions clustering between aa 50 and 69. This region of the nucleocapsid protein is known as an immunodominant epitope for CD4+ T-lymphocytes, however the impact of these mutations ...

journal_title：Journal of medical virology

authors： Torre F,Cramp M,Owsianka A,Dornan E,Marsden H,Carman W,Williams R,Naoumov NV

更新日期：2004-03-01 00:00:00

abstract：:Two hundred and thirty fecal specimens were collected from children (up to 5 years of age) admitted with suspected rotaviral gastroenteritis at four Irish hospitals (Cork University Hospital, Mercy Hospital, Cork, Waterford Regional Hospital, and Kerry General Hospital) in the southern region of Ireland, between 2001 ...

journal_title：Journal of medical virology

authors： Reidy N,O'Halloran F,Fanning S,Cryan B,O'Shea H

更新日期：2005-12-01 00:00:00

abstract：:ZIKV infection has become a global threat spreading across 31 countries in Central America, South America, and the Caribbean. However, little information is available about the molecular epidemiology of ZIKV. Shared mutation of a threonine residue to alanine at the same position in the C terminal of NS5 sequences was ...

journal_title：Journal of medical virology

authors： Adiga R

更新日期：2016-10-01 00:00:00

abstract：:During the period 2007-2008 several epizootics of Yellow fever with dead of monkeys occurred in southeastern Brasil, Paraguay, and northeastern Argentina. In 2008 after a Yellow fever outbreak an exhaustive prevention campaign took place in Argentina using 17D live attenuated Yellow fever vaccine. This vaccine is cons...

journal_title：Journal of medical virology

authors： Pires-Marczeski FC,Martinez VP,Nemirovsky C,Padula PJ

更新日期：2011-12-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) can lead to a massive cytokine release. The use of the anti-interleukin-6 receptor monoclonal antibody tocilizumab (TCZ) has been proposed in this hyperinflammatory phase, although supporting evidence is limited. We retrospectively analyzed 88 consecutive patients with COVID-19 pneu...

journal_title：Journal of medical virology

authors： Fernández-Ruiz M,López-Medrano F,Pérez-Jacoiste Asín MA,Maestro de la Calle G,Bueno H,Caro-Teller JM,Catalán M,de la Calle C,García-García R,Gómez C,Laguna-Goya R,Lizasoáin M,Martínez-López J,Origüen J,Pablos JL,Ripoll M,

更新日期：2021-02-01 00:00:00

abstract：:The worldwide infection rate of herpesvirus is high, but the detailed prevalence in China, especially the central area, remains unclear. In the present study, the prevalence of herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV) was investigated in 303 healthy adults in Wuhan, a repr...

journal_title：Journal of medical virology

authors： Wen L,Qiu Y,Cheng S,Jiang X,Ma YP,Fang W,Wang W,Cui J,Ruan Q,Zhao F,Hu F,Luo MH

更新日期：2018-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the use of dried blood spots stored on filter paper as a means to provide specimens for virologic surveillance for measles virus (MV) in situations when the reverse cold chain is not available. Two single-step RT-PCR assays were evaluated for sensitivity of detection of MV nuc...

journal_title：Journal of medical virology

authors： Katz RS,Premenko-Lanier M,McChesney MB,Rota PA,Bellini WJ

更新日期：2002-08-01 00:00:00

abstract：:The relationships between host immune factors and HIV-1 disease progression are still in dispute. The RANTES SNPs exhibit distinct ethnic distribution and are associated with different effects on the course of HIV infection. Therefore, impact of RANTES gene polymorphism on HIV-1 transmission and progression needs to b...

journal_title：Journal of medical virology

authors： Rathore A,Chatterjee A,Sivarama P,Yamamoto N,Singhal PK,Dhole TN

更新日期：2008-07-01 00:00:00

abstract：:Human papillomavirus (HPV) is known to be the cause of almost all cervical cancers. The genotypes have been classified into high and low risk types according to their oncogenic potential. However, data for many of the genotypes are limited and some (HPV-26, 53, and 66) have no agreed status. A study was undertaken to ...

journal_title：Journal of medical virology

authors： Brestovac B,Harnett GB,Smith DW,Shellam GR,Frost FA

更新日期：2005-05-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00

abstract：:The effect on cellular (c) oncogene RNA levels was investigated after infection of permissive cells with cell culture adapted strains (AD-169, C-87, Davis) and unadapted clinical isolates (82-1, 84-2, 85-1) of human cytomegalovirus (HCMV). The results indicate that both adapted and unadapted strains of HCMV induce sub...

journal_title：Journal of medical virology

authors： Boldogh I,AbuBakar S,Fons MP,Deng CZ,Albrecht T

更新日期：1991-08-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects),...

journal_title：Journal of medical virology

authors： Ferrante P,Caldarelli-Stefano R,Omodeo-Zorini E,Cagni AE,Cocchi L,Suter F,Maserati R

更新日期：1997-07-01 00:00:00

abstract：:During the 1998-1999 influenza season, two distinct influenza B virus Yamagata group strains were isolated from the patients of a private clinic. Each responded differently to monoclonal antibodies (Mabs) 5H4 and 8B3 on staining, and hemagglutination inhibition and neutralizing tests. When the analysis of nucleotide s...

journal_title：Journal of medical virology

authors： Nakagawa N,Kubota R,Morikawa S,Nakagawa T,Baba K,Okuno Y

更新日期：2001-12-01 00:00:00

abstract：:Although it is understood that low-risk human papillomavirus (HPV) genotypes are associated with genital warts, there have been very few published studies reporting the genotype-specific prevalence of HPV among Chinese population. The aim of the study was to assess the prevalence of HPV genotypes in genital warts acro...

journal_title：Journal of medical virology

authors： Chang L,Ci P,Shi J,Zhai K,Feng X,Colombara D,Wang W,Qiao Y,Chen W,Wu Y

更新日期：2013-10-01 00:00:00

abstract：:The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...

journal_title：Journal of medical virology

authors： Arora NK,Nanda SK,Gulati S,Ansari IH,Chawla MK,Gupta SD,Panda SK

更新日期：1996-03-01 00:00:00

abstract：:The number of new HIV diagnoses is increasing in the western world and transmission clusters have been recently identified among men having sex with men despite Highly Active Antiretroviral Therapy efficacy. The objective of this study was to assess temporal trends, epidemiological, clinical and virological characteri...

journal_title：Journal of medical virology

authors： Tamalet C,Ravaux I,Moreau J,Brégigeon S,Tourres C,Richet H,Abat C,Colson P

更新日期：2015-08-01 00:00:00

abstract：:Polymorphisms upstream interleukin (IL)-28B gene and serum levels of interferon gamma inducible protein-10 (IP-10) are associated with spontaneous and treatment-induced hepatitis C virus (HCV) clearance. Patients with seronegative occult HCV infection are anti-HCV and serum HCV-RNA negative but have viral RNA in liver...

journal_title：Journal of medical virology

authors： Bartolomé J,Castillo I,Quiroga JA,Carreño V

更新日期：2016-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a single-stranded RNA virus related to the Flaviviridae family, and striking nucleotide sequence diversity has been reported among HCV isolates from different geographic areas. To study the distribution HCV genotypes among disease group in Korea, we subtyped HCV using the method of Okamoto e...

journal_title：Journal of medical virology

authors： Lee DS,Sung YC,Whang YS

更新日期：1996-05-01 00:00:00

abstract：:Total RNA from normal adult woodchucks was analyzed using membrane arrays containing human cDNA clones, and the gene expression patterns were compared to human liver. Various hybridization and wash conditions were examined. In both the woodchuck and human livers, 352 genes were identified as highly expressed (Z-scores...

journal_title：Journal of medical virology

authors： Rinaudo JA,Gerin JL

更新日期：2004-10-01 00:00:00

abstract：:The presence of hepatitis GB virus C (GBV-C), also known as hepatitis G virus (HGV), and hepatitis C virus (HCV) were investigated in sera from 45 hemophiliacs from nine locations in Nicaragua using a nested polymerase chain reaction (PCR). Primers used to detect GBV-C and HCV derived from the helicase region and 5'UT...

journal_title：Journal of medical virology

authors： González-Pérez MA,Norder H,Bergström A,Lopéz E,Visoná KA,Magnius LO

更新日期：1997-06-01 00:00:00

abstract：:The aim of this study was to assess the seroprevalence, viremia, genotype distribution, and demographic history of hepatitis C virus (HCV) in the Republic of the Congo. Testing was carried out on sera samples collected in 2005 from 807 Bantus belonging to the Kongo, Teke, and Ngala subgroups and 80 Pygmies. Positive H...

journal_title：Journal of medical virology

authors： Cantaloube JF,Gallian P,Bokilo A,Jordier F,Biagini P,Attoui H,Chiaroni J,de Micco P

更新日期：2010-04-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:We have previously reported that concanavalin A-immobilized polystyrene nanospheres (Con A-NS) could efficiently capture HIV-1 particles and that intranasal immunization with inactivated HIV-1-capturing nanospheres (HIV-NS) induced vaginal anti-HIV-1 IgA antibody response in mice. In this study, to evaluate the protec...

journal_title：Journal of medical virology

authors： Miyake A,Akagi T,Enose Y,Ueno M,Kawamura M,Horiuchi R,Hiraishi K,Adachi M,Serizawa T,Narayan O,Akashi M,Baba M,Hayami M

更新日期：2004-07-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:Genital herpes is a common, distressing infection whose incidence has been underestimated. Recent serological surveys, employing type-specific antibody assays, show a rising prevalence of previous herpes simplex virus (HSV) type 2 infections in post-adolescent populations in developed countries; many of these infectio...

journal_title：Journal of medical virology

authors： Kinghorn GR

更新日期：1993-01-01 00:00:00

abstract：:One hundred twelve peripheral blood specimens were tested for the presence of cytomegalovirus (CMV) by the tube culture indirect immunoperoxidase (TC-IPA) procedure, the shell vial assay [shell vials were pre- and postinoculation treated with medium containing 2 of 10% fetal bovine serum (FBS) or 100 micrograms% corti...

journal_title：Journal of medical virology

authors： Lipson SM,Kaplan MH,Simon JK,Ciamician Z,Tseng LF

更新日期：1992-09-01 00:00:00

abstract：:Resistance to adamantanes for treating influenza A(H3N2) has increased dramatically, worldwide, over the past 5 years. A comprehensive 10-year data set on the rise of adamantane-resistance in Hong Kong is reported. Nucleotide sequences encoding the M2-ion channel of influenza A(H3N2) were obtained from 281 H3N2 isolat...

journal_title：Journal of medical virology

authors： Tang JW,Ngai KL,Wong JC,Lam WY,Chan PK

更新日期：2008-05-01 00:00:00

abstract：:We previously reported an age-associated impairment of serum immunoglobulin G (IgG) antibody responses to inactivated influenza virus vaccine. The present study extends these observations by examining the IgG subclass distribution of vaccine responses measured by enzyme linked immunosorbent assay in healthy adults age...

journal_title：Journal of medical virology

authors： Powers DC

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...

journal_title：Journal of medical virology

authors： Mabayoje DA,Cutino-Moguel T,Haigh J,Wilks M,Welch CA,Melzer M

更新日期：2020-10-15 00:00:00