H1 genotype of measles virus was detected in outbreaks in Japan after 2000.


:We investigated the molecular epidemiology and biological characteristics of wild measles viruses isolated since 1984 in Japan. The circulating measles virus was of genotype C1 before 1985, D3 from 1987 to 1990, and D5 from 1990 to 1997. It was replaced by the same cluster of Chicago-type D3 strain from 1997 to 1999. In 2000, D5 recirculated with sporadic cases caused by genotype H1. The H1 genotype became dominant in 2001 with a minor distribution of D5. No significant difference was observed in neutralizing titers against C1, D3, D5, and H1 when we used sera having high neutralizing titers. However, some D3 and H1 strains were not completely neutralized with low levels of neutralizing antibody, and maintaining high levels of measles antibodies would be required for the control measles outbreaks.


J Med Virol


Zhou J,Fujino M,Inou Y,Kumada A,Aoki Y,Iwata S,Nakayama T





Has Abstract


2003-08-01 00:00:00












  • Shedding of herpes simplex virus type 1 into saliva in patients with orofacial fracture.

    abstract::Shedding of herpes simplex virus type 1 (HSV-1) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV-1 specific antibody. Virus shedding into saliva w...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Kameyama T,Futami M,Nakayoshi N,Sujaku C,Yamamoto S

    更新日期:1989-06-01 00:00:00

  • Comparison of characteristics between patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA and those with GBV-C/HGV E2-antibody in patients with hemophilia.

    abstract::We compared characteristics of patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA to those of patients with GBV-C/HGV E2-antibody. GBV-C/HGV RNA and GBV-C/HGV antibody were assayed in 83 persons with hemophilia using a reverse transcription-polymerase chain reaction and an enzyme-linked immunosorbent assay, re...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Toyoda H,Takahashi I,Fukuda Y,Hayakawa T,Takamatsu J

    更新日期:2000-01-01 00:00:00

  • Characterisation of a series of human immunodeficiency virus isolates derived sequentially from a single patient.

    abstract::Five HIV-1 isolates were obtained sequentially from a single seropositive individual during the later stages of AIDS. Four of these isolates were adapted to grow in a continuous human T-lymphocytic cell line. Comparative biological and biochemical studies of the virus isolates were made using persistently infected cul...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Farrar GH,Roff MA,Amin T,Ball J,Parrett AM,Battacharyya U,Booth J,Wansbrough-Jones MH,Greenaway PJ

    更新日期:1991-06-01 00:00:00

  • Analysis of hepatitis C virus strains circulating in Republic of the Congo.

    abstract::The aim of this study was to assess the seroprevalence, viremia, genotype distribution, and demographic history of hepatitis C virus (HCV) in the Republic of the Congo. Testing was carried out on sera samples collected in 2005 from 807 Bantus belonging to the Kongo, Teke, and Ngala subgroups and 80 Pygmies. Positive H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Cantaloube JF,Gallian P,Bokilo A,Jordier F,Biagini P,Attoui H,Chiaroni J,de Micco P

    更新日期:2010-04-01 00:00:00

  • Correlation of HTLV-1 Tax genetic diversity with HTLV-1 associated myelopathy/tropical spastic paraparesis progression and HTLV-1a genotypes in an HTLV-1 endemic region in Argentina.

    abstract::The oncoprotein Tax was characterized genetically from a large cohort of human T-cell lymphotropic virus type 1 (HTLV-1) seropositive individuals from the most endemic region of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 infection in Argentina, the province of San Salvador de Jujuy....

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Iñiguez AM,Gastaldello R,Otsuki K,Balangero M,Carvalho Costa F,Remondegui C,Paula Vicente AC,Gallego S

    更新日期:2010-08-01 00:00:00

  • Development and evaluation of a conventional RT-PCR for differentiating emerging influenza B/Victoria lineage viruses with hemagglutinin amino acid deletion from B/Yamagata lineage viruses.

    abstract:BACKGROUND:Recent influenza B/Victoria lineage viruses contain amino acid deletions at positions 162 to 164 of the haemagglutinin (HA) protein. These amino acid deletions have affected the detection of B/Victoria lineage viruses by the lineage-specific conventional reverse-transcription polymerase chain reaction (RT-PC...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Chan WM,Wong LH,So CF,Chen LL,Wu WL,Ip JD,Lam AH,Yip CCY,Yuen KY,To KKW

    更新日期:2020-03-01 00:00:00

  • Characteristics of lamivudine-resistant hepatitis B virus (HBV) strains with and without breakthrough hepatitis in patients with chronic hepatitis B evaluated by serial HBV full-genome sequences.

    abstract::Lamivudine therapy often causes breakthrough of hepatitis B virus (HBV) DNA and breakthrough hepatitis. The aim of this study was to determine the viral factors that relate to HBV-DNA breakthrough with and without breakthrough hepatitis. Among 82 patients with chronic hepatitis B (CHB) who received lamivudine at a dos...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Horiike N,Duong TN,Michitaka K,Joko K,Hiasa Y,Konishi I,Yano M,Onji M

    更新日期:2007-07-01 00:00:00

  • Anal HPV 16 and 18 viral load: A comparison between HIV-negative and -positive MSM and association with persistence.

    abstract::Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Marra E,King A,van Logchem E,van der Weele P,Mooij SH,Heijman T,Meijer CJLM,Verhagen DWM,van der Sande MAB,Schim van der Loeff MF

    更新日期:2018-01-01 00:00:00

  • Seroepidemiology of hepatitis A, B, C, and E viruses infection among preschool children in Taiwan.

    abstract::Taiwan was a hyperendemic area for hepatitis A and B viruses (HAV and HBV) infection before late 1980s. To study the seroprevalence of hepatitis A, B, C, and E viruses (HCV and HEV) infection among preschool children in Taiwan, a community-based survey was carried out in 54 kindergartens in 10 urban areas, 10 rural ar...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Lin JB,Lin DB,Chen SC,Chen PS,Chen WK

    更新日期:2006-01-01 00:00:00

  • Detection of integrated hepatitis B virus DNA in hepatocellular carcinoma cell lines by nonradioactive in situ hybridization.

    abstract::A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Tay N,Chan SH,Ren EC

    更新日期:1990-04-01 00:00:00

  • Serological studies of an enterically transmitted non-A, non-B hepatitis in Somalia.

    abstract::An outbreak of an acute sporadic viral hepatitis occurring at three villages in the lower Shebli region of southern Somalia was studied. Sera were examined for antibodies to hepatitis E virus (HEV) antigen by a recently developed enzyme-linked immunosorbent assay. The prevalence of anti-HEV ranged from 77.8% to 94.0% ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Mushahwar IK,Dawson GJ,Bile KM,Magnius LO

    更新日期:1993-07-01 00:00:00

  • Selection of drug-resistant HIV-1 during the early phase of viral decay is uncommon in treatment-naïve patients initiated on a three- or four-drug antiretroviral regimen including lamivudine.

    abstract::Therapy failure due to drug resistance development is a common phenomenon in HIV-infected patients. However, when the drug pressure leads to the earliest selection of drug-resistant HIV-1 populations is still unclear. In this study, the extent to which selection of the HIV-1 reverse transcriptase M184I/V mutations occ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Bergroth T,Ekici H,Gisslén M,Loes SK,Goh LE,Freedman A,Lampe F,Johnson MA,Sönnerborg A

    更新日期:2009-01-01 00:00:00

  • High human herpesvirus 8 seroprevalence in populations from Western Balkan countries.

    abstract::Patterns of endemicity of human herpesvirus 8 (HHV8) are still undefined in some European populations, such as those from Western Balkan countries. Serum samples from 605 human immunodeficiency virus-seronegative subjects (299 Albanians and 306 Kosovars) were tested for the presence of HHV8 antibodies to a capsid-rela...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Chironna M,Tosatti MA,Di Gangi IM,Sallustio A,Germinario C,Coluzzi M,Quarto M,Chieco-Bianchi L,Calabrò ML

    更新日期:2006-07-01 00:00:00

  • Virological patterns of HCV patients with failure to interferon-free regimens.

    abstract::The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

    更新日期:2018-05-01 00:00:00

  • Clinical and epidemiological characteristics of 320 deceased patients with COVID-19 in an Italian Province: A retrospective observational study.

    abstract::Studies have described clinical features of patients with coronavirus disease (COVID-19). However, limited data concerning the clinical characteristics of the Italian deaths are available. We aim to describe the clinical and epidemiological characteristics of 320 deceased from the Italian experience. We retrospectivel...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Biagi A,Rossi L,Malagoli A,Zanni A,Sticozzi C,Comastri G,Gandolfi S,Villani GQ

    更新日期:2020-11-01 00:00:00

  • False RIA IgM titres to herpes simplex virus and cytomegalovirus: factors causing them, and their absorption by protein A-Sepharose/IgG-protein A-Sepharose.

    abstract::A method for the absorption of false radioimmunoassay (RIA) IgM titres against herpes simplex virus (HSV) and cytomegalovirus (CMV) is presented. The serum specimens were absorbed by a mixture of protein A-Sepharose and protein A-Sepharose saturated with normal human gamma globulin (PAS/IgG). The detection of rheumato...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Torfason EG,Diderholm H

    更新日期:1982-01-01 00:00:00

  • Use of a generic polymerase chain reaction assay detecting human T-lymphotropic virus (HTLV) types I, II and divergent simian strains in the evaluation of individuals with indeterminate HTLV serology.

    abstract::In countries with a low prevalence of human T-lymphotropic virus (HTLV) infection, indeterminate HTLV serologies are a major problem in blood bank screening because of the uncertainties about infection in these cases. The recent discovery of two new types of simian T-lymphotropic viruses (STLV), which give an HTLV-ind...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Vandamme AM,Van Laethem K,Liu HF,Van Brussel M,Delaporte E,de Castro Costa CM,Fleischer C,Taylor G,Bertazzoni U,Desmyter J,Goubau P

    更新日期:1997-05-01 00:00:00

  • Emergence of the GII4/2006b variant and recombinant noroviruses in China.

    abstract::Noroviruses are an important cause of acute gastroenteritis. Increasing data showed that the GII-4 strains are predominant worldwide and new GII-4 variants emerge every 1-2 years causing major epidemics. Surveillance of gastroenteritis in hospitalized children under 5 years of age in China is described. Among 1,110 sp...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Jin M,Xie HP,Duan ZJ,Liu N,Zhang Q,Wu BS,Li HY,Cheng WX,Yang SH,Yu JM,Xu ZQ,Cui SX,Zhu L,Tan M,Jiang X,Fang ZY

    更新日期:2008-11-01 00:00:00

  • Hepatitis B virus markers in anti-HBc only positive individuals.

    abstract::Isolated reactivity to hepatitis B virus (HBV) core antigen (anti-HBc) is observed relatively frequently in immunocompromised individuals, intravenous drug abusers (IVDA), and in the presence of HCV infection. The reason for the lack of HBsAg is not clear. The aim of the present study was to investigate which factors ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Weber B,Melchior W,Gehrke R,Doerr HW,Berger A,Rabenau H

    更新日期:2001-07-01 00:00:00

  • Immunohistological detection of human herpes virus 6 in formalin-fixed, paraffin-embedded lung tissues.

    abstract::Human herpes virus type 6 (HHV-6) infection is widespread in healthy individuals. The only definite disease association is with exanthem subitum in infants though the virus has been linked with a variety of other diseases including interstitial pneumonitis in bone marrow allograft recipients. In order to investigate t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Pitalia AK,Liu-Yin JA,Freemont AJ,Morris DJ,Fitzmaurice RJ

    更新日期:1993-10-01 00:00:00

  • Cytomegalovirus excretion after bone marrow transplantation cannot be predicted from the pre-transplant level of IgG antibodies.

    abstract::The relationship of pre-bone-marrow transplant recipient and donor cytomegalovirus (CMV) antibody level to post-transplant recipient CMV excretion was investigated. CMV excretion was found to be related to pre-transplant recipient serological status, but not to level of antibody. This therefore contrasts with herpes s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Pillay D,Webster A,Lee D,Prentice HG,Griffiths PD

    更新日期:1991-04-01 00:00:00

  • High circulating levels of N-terminal pro-brain natriuretic peptide and interleukin 6 in patients with mixed cryoglobulinemia.

    abstract::Many patients with mixed cryoglobulinemia and chronic HCV infection experience symptoms, such as dyspnea, which sometimes do not seem to indicate the involvement of the liver but rather the symptoms of heart failure. To our knowledge, there has been no other study evaluating the serum levels of N-terminal pro-brain na...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Antonelli A,Ferri C,Ferrari SM,Ghiri E,Galetta F,Franzoni F,Santoro G,Fallahi P

    更新日期:2010-02-01 00:00:00

  • Application strategies of serum HBV DNA detection in HBV infection patients: A retrospective study of 5611 specimens.

    abstract::The detection of hepatitis B virus (HBV) DNA plays a critical role in determining the level of viral replication in HBV-infected patients. However, how to select appropriate HBV DNA detection method, low-sensitivity (ls) and hypersensitivity (hs) remains unclear. In this study, hepatitis B surface antigen (HBsAg), hep...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Liu C,Wu W,Shang S,Huang E,Xun Z,Lin J,Chen T,Yang B,Chen J,Ou Q

    更新日期:2019-02-01 00:00:00

  • Homotypic immune response to primary infection with rotavirus serotype G1.

    abstract::Some aspects of rotavirus humoral immunity were assessed on the basis of distinguishing serotype-specific specificities (VP4/VP7) by using rotavirus reassortants, human and animal strains in neutralization assays in serum samples obtained during the acute phase, and 1, 6 and 12 months after primary natural infection. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Rojas AM,Boher Y,Guntiñas MJ,Pérez-Schael I

    更新日期:1995-12-01 00:00:00

  • Outbreaks of hepatitis A in England and Wales associated with two co-circulating hepatitis A virus strains.

    abstract::During 2002, an upsurge in frequency of hepatitis A outbreaks among injecting drug users was observed in England and Wales. As lack of risk factor information and the high mobility of the cases made linkage of outbreaks difficult, the relationship of nucleotide sequences in the VP1/2PA junction of the hepatitis A viru...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Ngui SL,Granerod J,Jewes LA,Crowcroft NS,Teo CG,2002 Hepatitis A Outbreaks Investigation Network.

    更新日期:2008-07-01 00:00:00

  • Emergence of clusters of CRF02_AG and B human immunodeficiency viral strains among men having sex with men exhibiting HIV primary infection in southeastern France.

    abstract::The number of new HIV diagnoses is increasing in the western world and transmission clusters have been recently identified among men having sex with men despite Highly Active Antiretroviral Therapy efficacy. The objective of this study was to assess temporal trends, epidemiological, clinical and virological characteri...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Tamalet C,Ravaux I,Moreau J,Brégigeon S,Tourres C,Richet H,Abat C,Colson P

    更新日期:2015-08-01 00:00:00

  • New variations of Epstein-Barr virus-encoded small RNA genes in nasopharyngeal carcinomas, gastric carcinomas, and healthy donors in northern China.

    abstract::It has been generally believed that the Epstein-Barr virus (EBV)-encoded small RNA 1 and 2 (EBER1 and EBER2) genes are conserved as two families that correlated with type 1 (B95-8) and type 2 (AG876 or P3HR-1) EBV strains. EBER polymorphism and its association with EBV-associated disease have not received much attenti...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Wang Y,Zhang X,Chao Y,Jia Y,Xing X,Luo B

    更新日期:2010-05-01 00:00:00

  • Genotype I hepatitis A virus introduction in Italy: Bayesian phylogenetic analysis to date different epidemics.

    abstract::Despite a significant decrease in acute hepatitis A in the last 2 decades in Italy, outbreaks were observed occurring mostly in southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze the origin of these epidemics. With this aim, 5 different data sets of hepatitis A virus sequences were built...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Cella E,Riva E,Angeletti S,Fogolari M,Blasi A,Scolamacchia V,Spoto S,Bazzardi R,Lai A,Sagnelli C,Sagnelli E,Ciccozzi M

    更新日期:2018-09-01 00:00:00

  • UV-inactivated measles virus stimulates human and mice naive lymphocytes to proliferate in vitro.

    abstract::Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Tu R

    更新日期:1995-06-01 00:00:00

  • Hemagglutinin-neuraminidase sequence and phylogenetic analyses of mumps virus isolates from a vaccinated population in Singapore.

    abstract::During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isola...

    journal_title:Journal of medical virology

    pub_type: 杂志文章


    authors: Lim CS,Chan KP,Goh KT,Chow VT

    更新日期:2003-06-01 00:00:00