HIV excretion patterns and specific antibody responses in body fluids.

Abstract:

:HIV excretion patterns and specific antibody responses were evaluated in blood, semen, female genital secretions, saliva, and crevicular fluid. Samples were examined for infectious virus, viral antigens, viral nucleic acid, HIV specific IgG, IgA, anti-nef, and anti-p24. Viral load in peripheral blood appeared to increase with disease progression. The proportion of patients with antibody responses specific for nef and p24 was also lower among patients with more advanced disease. Infectious virus and viral antigens were detected infrequently and at lower levels in body fluids than in blood, which may reflect the presence of local antibodies. HIV nucleic acid was detected in some semen and saliva samples in the absence of infectious virus.

journal_name

J Med Virol

authors

O'Shea S,Cordery M,Barrett WY,Richman DD,Bradbeer C,Banatvala JE

doi

10.1002/jmv.1890310409

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

291-6

issue

4

eissn

0146-6615

issn

1096-9071

journal_volume

31

pub_type

杂志文章
  • Neutralization test for BK virus: plaque reduction detected by immunoperoxidase staining.

    abstract::We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890190311

    authors: Flaegstad T,Traavik T,Christie KE,Joergensen J

    更新日期:1986-07-01 00:00:00

  • Human herpesvirus 8 and human herpesvirus 2 infections in prison population.

    abstract::Incarcerated persons have high rates of infectious diseases. Few data on the prevalence of sexually transmitted diseases in prisoners are available. This multi-center cross-sectional study enrolled 973 inmates from eight Italian prisons. Demographic and behavioral data were collected using an anonymous standardized qu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jmv.20774

    authors: Sarmati L,Babudieri S,Longo B,Starnini G,Carbonara S,Monarca R,Buonomini AR,Dori L,Rezza G,Andreoni M,Gruppo di Lavoro Infettivologi Penitenziari (GLIP).

    更新日期:2007-02-01 00:00:00

  • Titration of hepatitis B virus infectivity in the sera of pre-acute and late acute phases of HBV infection: transmission experiments to chimeric mice with human liver repopulated hepatocytes.

    abstract::Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21320

    authors: Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

    更新日期:2008-12-01 00:00:00

  • Detection of human papillomavirus in esophageal carcinoma.

    abstract::The aim of the study was to assess the prevalence of human papillomavirus (HPV) in the esophagus in the coastal region of Eastern Guangdong, Southern China, an area with a high incidence of esophageal carcinoma. Fresh surgical resection esophageal specimens were obtained from 176 esophageal carcinoma patients admitted...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10219

    authors: Shen ZY,Hu SP,Lu LC,Tang CZ,Kuang ZS,Zhong SP,Zeng Y

    更新日期:2002-11-01 00:00:00

  • Detection of human immunodeficiency virus (HIV) genome from the lymphocytes of homosexual men.

    abstract::Human immunodeficiency virus (HIV) is the primary etiological agent of acquired immunodeficiency syndrome (AIDS). This virus can be transmitted by blood or blood products. Homosexual males (HM) are regarded as one of the high-risk groups for AIDS. Lymphocytes obtained from HM were used for cocultivation with fresh HIV...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890230404

    authors: Lee YS,Baker L

    更新日期:1987-12-01 00:00:00

  • Detection of IgM antibodies to delta antigen after coinfection and superinfection with the delta virus.

    abstract::A sensitive microtitre radioimmunoassay was developed for detection of IgM antibodies to delta antigen. The assay was based on the selective binding of IgM from test sera to antihuman IgM (u-chain specific) fixed to wells of a microtitre plate, and utilized delta antigen extracted from the liver of an experimentally i...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890200403

    authors: Dimitrakakis M,Waters MJ,Wootton A,Gust I

    更新日期:1986-12-01 00:00:00

  • Homotypic immune response to primary infection with rotavirus serotype G1.

    abstract::Some aspects of rotavirus humoral immunity were assessed on the basis of distinguishing serotype-specific specificities (VP4/VP7) by using rotavirus reassortants, human and animal strains in neutralization assays in serum samples obtained during the acute phase, and 1, 6 and 12 months after primary natural infection. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470418

    authors: Rojas AM,Boher Y,Guntiñas MJ,Pérez-Schael I

    更新日期:1995-12-01 00:00:00

  • Association between detectable SARS-COV-2 RNA in anal swabs and disease severity in patients with coronavirus disease 2019.

    abstract:BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was found in the intestines and feces, but its clinical significance is not completely clear. We aim to characterize the longitudinal test results of SARS-CoV-2 RNA in anal swabs and to explore the association with disease severity. METHODS:We...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26307

    authors: Lin W,Xie Z,Li Y,Li L,Wen C,Cao Y,Chen X,Ou X,Hu F,Li F,Tang X,Cai W,Li L

    更新日期:2021-02-01 00:00:00

  • In vitro neutralization of HSV-2: inhibition by binding of normal IgG and purified Fc to virion Fc receptor (FcR).

    abstract::We designed experiments to assess the effects of binding of the HSV-2 Fc receptor (FcR) to purified rabbit nonimmune IgG and purified Fc. Purified Fc (75 micrograms) or nonimmune IgG (100 micrograms) when bound to HSV-2 did not reduce infectivity but did protect the virions against thermal inactivation at 37 degrees C...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890130307

    authors: Dowler KW,Veltri RW

    更新日期:1984-01-01 00:00:00

  • Molecular epidemiology of astroviruses in Japan from 1995 to 1998 by reverse transcription-polymerase chain reaction with serotype-specific primers (1 to 8).

    abstract::In addition to the serotype-specific primers described previously (1 to 7), a new serotype 8-specific primer has been designed, allowing detection of all astrovirus serotypes. A total of 1,382 diarrheal stool samples in 5 regions in Japan were examined by reverse transcription-polymerase chain reaction (RT-PCR). The i...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Sakamoto T,Negishi H,Wang QH,Akihara S,Kim B,Nishimura S,Kaneshi K,Nakaya S,Ueda Y,Sugita K,Motohiro T,Nishimura T,Ushijima H

    更新日期:2000-07-01 00:00:00

  • Identification of a human group C rotavirus in Malaysia.

    abstract::Stool specimens from 334 infants and young children hospitalized with diarrhea in the General Hospital, Kuala Lumpur, Malaysia between August and November, 1987 were analyzed for the presence of rotavirus double-stranded (ds) RNA by polyacrylamide gel electrophoresis. Of the 334 specimens analyzed, 32 (9.6%) were posi...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890430302

    authors: Rasool NB,Hamzah M,Jegathesan M,Wong YH,Qian Y,Green KY

    更新日期:1994-07-01 00:00:00

  • Monitoring of patients for cytomegalovirus after organ transplantation by centrifugation culture and PCR.

    abstract::A modified centrifugation culture technique and a polymerase chain reaction (PCR) is described for detection of early antigen and IE antigen DNA, respectively, for rapid and sensitive monitoring of active cytomegalovirus (HCMV) infection after organ transplantation. In a preliminary study, 541 clinical specimens (bloo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890380404

    authors: Prösch S,Kimel V,Dawydowa I,Krüger DH

    更新日期:1992-12-01 00:00:00

  • Clinical Significance of Cellular Immunity Function and Inflammatory Factors Assays in Alveolar Lavage Fluid for Severe COVID-19 Pneumonia.

    abstract::In this study, we aimed to investigate the changes of lymphocyte subsets (CD3+ , CD4+ , CD8+ ) and inflammatory factors (interleukin-6 [IL-6], hypersensitive C-reactive protein [HS-CRP], and procalcitonin [PCT]) of alveolar lavage fluid in patients with severe corona virus-2019 (COVID-19) pneumonia and their clinical ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26827

    authors: Liao L,Yang GH

    更新日期:2021-01-28 00:00:00

  • Utility of IgM ELISA, TaqMan real-time PCR, reverse transcription PCR, and RT-LAMP assay for the diagnosis of Chikungunya fever.

    abstract::Chikungunya fever a re-emerging infection with expanding geographical boundaries, can mimic symptoms of other infections like dengue, malaria which makes the definitive diagnosis of the infection important. The present study compares the utility of four laboratory diagnostic methods viz. IgM capture ELISA, an in house...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23406

    authors: Reddy V,Ravi V,Desai A,Parida M,Powers AM,Johnson BW

    更新日期:2012-11-01 00:00:00

  • Development and validation of a new serum standard for the measurement of anti-HEV antibodies in animals.

    abstract::Although hepatitis E virus (HEV) infection is a zoonosis, there is, currently, no standardized assay for quantitatively measuring anti-HEV antibody levels in HEV animal reservoirs. In this study, anti-HEV antibody positive serum from a rabbit (RS26) was calibrated by dose-response parallel line assay using the World H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24651

    authors: Zhang Y,Wang L,Zeng H,Gong W,Wang L,Zhuang H

    更新日期:2017-03-01 00:00:00

  • Infection of a human retinal pigment epithelial cell line with human herpesvirus 6 variant A.

    abstract::A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells, herpesvirus nucle...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Arao Y,Soushi S,Sato Y,Moriishi E,Ando Y,Yamada M,Padilla J,Uno F,Nii S,Kurata T

    更新日期:1997-10-01 00:00:00

  • Epstein-Barr virus, B cell lymphoproliferative disease, and SCID mice: modeling T cell immunotherapy in vivo.

    abstract::Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) arises in up to 10% of organ transplant recipients and is fatal in ∼50% of cases. PTLD can be modeled in SCID mice using EBV+ve human B lymphoblastoid cell lines (BLCLs), and the current study investigated intraperitoneal (ip) inocu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22164

    authors: Johannessen I,Bieleski L,Urquhart G,Watson SL,Wingate P,Haque T,Crawford DH

    更新日期:2011-09-01 00:00:00

  • Supernatants from dengue virus type-2 infected macrophages induce permeability changes in endothelial cell monolayers.

    abstract::The ability of dengue virus-infected human monocyte-derived macrophages to induce permeability changes in primary human umbilical vein endothelial cells was investigated. Supernatants from dengue virus type 2-infected monocyte-derived macrophages increased permeability in human umbilical vein endothelial cell monolaye...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10340

    authors: Carr JM,Hocking H,Bunting K,Wright PJ,Davidson A,Gamble J,Burrell CJ,Li P

    更新日期:2003-04-01 00:00:00

  • Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: an age- and sex-matched case-control study.

    abstract::It was reported previously food-borne transmission of hepatitis E virus (HEV) to humans from deer meat. The present study attempted to clarify whether eating uncooked deer meat is a major epidemiological risk factor for HEV infection in Kasai, a city in western Japan. In total, 45 volunteer subjects with experience of...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20147

    authors: Tei S,Kitajima N,Ohara S,Inoue Y,Miki M,Yamatani T,Yamabe H,Mishiro S,Kinoshita Y

    更新日期:2004-09-01 00:00:00

  • Excretion of the novel polyomaviruses KI and WU in the stool of patients with hematological disorders.

    abstract::Infection with human polyomaviruses BKV and JCV is asymptomatic, and lifelong and widespread, among the general population. However, in the setting of immunosuppression, secondary to medications or viral infection, for example, with HIV, reactivation can occur and result in severe disease. In this study, stool specime...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21559

    authors: Babakir-Mina M,Ciccozzi M,Alteri C,Polchi P,Picardi A,Greco F,Lucarelli G,Arcese W,Perno CF,Ciotti M

    更新日期:2009-09-01 00:00:00

  • Hepatitis E virus genotype 1f outbreak in Bangladesh, 2018.

    abstract::Hepatitis E virus (HEV) infection is a significant public health issue in many developing countries, causing waterborne outbreaks as well as sporadic hepatitis. We report here an outbreak of HEV genotype 1f infection during April-May 2018 among people living at Halisohor, a low land in the southern part of Chottogram ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26739

    authors: Baki AA,Haque W,Giti S,Khan AA,Rahman MM,Jubaida N,Rahman M

    更新日期:2020-12-17 00:00:00

  • Diagnostic impact of the genetic variability of the hepatitis B virus surface antigen gene.

    abstract::The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of immunologic and molecular based assays. Genotyping studies show that the genetic diversity of HBV is very high even in industrialized countries. The analytical sensitivity of HBsAg and anti-HBs assays may be dependent on H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20610

    authors: Weber B

    更新日期:2006-01-01 00:00:00

  • Interferon-alpha therapy for chronic hepatitis B: early response related to pre-treatment changes in viral replication.

    abstract::Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...

    journal_title:Journal of medical virology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Heijtink RA,Janssen HL,Hop WC,Osterhaus AD,Schalm SW

    更新日期:2001-03-01 00:00:00

  • Study of influenza C virus infection in France.

    abstract::From November 2004 to April 2007, specimens were obtained from 2,281 patients with acute respiratory tract illness in Normandy, France. Eighteen strains of influenza C virus were detected in these samples using a combined tissue culture/RT-PCR diagnostic method. Most patients with influenza C virus infection (13/18) w...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21218

    authors: Gouarin S,Vabret A,Dina J,Petitjean J,Brouard J,Cuvillon-Nimal D,Freymuth F

    更新日期:2008-08-01 00:00:00

  • Quantification of infectious duck hepatitis B virus by radioimmunofocus assay.

    abstract::A simple method is described for the precise quantification of infectious duck hepatitis B virus (DHBV) in cell culture, using a radioimmunofocus assay (RIFA). Primary duck hepatocyte cell cultures were infected with serial dilutions of viral samples as for a plaque assay, but then maintained with liquid overlay mediu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Anderson DA,Grgacic EV,Luscombe CA,Gu X,Dixon R

    更新日期:1997-08-01 00:00:00

  • The variability of the serological response to SARS-corona virus-2: Potential resolution of ambiguity through determination of avidity (functional affinity).

    abstract::Data on the serological response toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 16 recent reports were analyzed and a high degree of variability was shown. Immunoglobulin M (IgM) responses were either found earlier than IgG, or together with IgG, later than IgG, or were missing. Therefore, clea...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.26262

    authors: Bauer G

    更新日期:2020-07-07 00:00:00

  • Hepatitis C virus infection of mononuclear cells from peripheral blood and liver infiltrates in chronically infected patients.

    abstract::The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34 persistently infected patients ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470112

    authors: Zignego AL,De Carli M,Monti M,Careccia G,La Villa G,Giannini C,D'Elios MM,Del Prete G,Gentilini P

    更新日期:1995-09-01 00:00:00

  • Association of hepatitis E virus with an outbreak of hepatitis in Pakistan: serologic responses and pattern of virus excretion.

    abstract::Hepatitis E virus (HEV), a positive-strand RNA agent, has been associated with enterically transmitted non-A, non-B hepatitis in Asia, Africa, and Mexico. To evaluate the role of HEV in an outbreak of hepatitis in Pakistan, we used immune electron microscopy to detect 1) antibody to HEV, for evidence of infection, and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890360205

    authors: Ticehurst J,Popkin TJ,Bryan JP,Innis BL,Duncan JF,Ahmed A,Iqbal M,Malik I,Kapikian AZ,Legters LJ

    更新日期:1992-02-01 00:00:00

  • Effects of drug resistance on viral load in patients failing antiretroviral therapy.

    abstract::Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20582

    authors: Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

    更新日期:2006-05-01 00:00:00

  • Differential effect of amantadine hydrochloride on the systemic and local immune response to influenza A.

    abstract::Anti-influenza serum and nasal antibody titers were followed during a double-blind, placebo-controlled, randomized study assessing the prophylactic efficacy of 50, 100, and 200 mg/day of amantadine hydrochloride against experimental challenge with influenza A/Beth/1/85. The geometric mean titers (GMT) of serum hemaggl...

    journal_title:Journal of medical virology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/jmv.1890270213

    authors: Reuman PD,Bernstein DI,Keely SP,Young EC,Sherwood JR,Schiff GM

    更新日期:1989-02-01 00:00:00