Abstract:
:HIV excretion patterns and specific antibody responses were evaluated in blood, semen, female genital secretions, saliva, and crevicular fluid. Samples were examined for infectious virus, viral antigens, viral nucleic acid, HIV specific IgG, IgA, anti-nef, and anti-p24. Viral load in peripheral blood appeared to increase with disease progression. The proportion of patients with antibody responses specific for nef and p24 was also lower among patients with more advanced disease. Infectious virus and viral antigens were detected infrequently and at lower levels in body fluids than in blood, which may reflect the presence of local antibodies. HIV nucleic acid was detected in some semen and saliva samples in the absence of infectious virus.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
O'Shea S,Cordery M,Barrett WY,Richman DD,Bradbeer C,Banatvala JEdoi
10.1002/jmv.1890310409subject
Has Abstractpub_date
1990-08-01 00:00:00pages
291-6issue
4eissn
0146-6615issn
1096-9071journal_volume
31pub_type
杂志文章abstract::We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...
journal_title:Journal of medical virology
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abstract::Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
pub_type: 杂志文章
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journal_title:Journal of medical virology
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更新日期:1995-12-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26307
更新日期:2021-02-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:1994-07-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890380404
更新日期:1992-12-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26827
更新日期:2021-01-28 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23406
更新日期:2012-11-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22164
更新日期:2011-09-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10340
更新日期:2003-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-09-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
abstract::Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-03-01 00:00:00
abstract::From November 2004 to April 2007, specimens were obtained from 2,281 patients with acute respiratory tract illness in Normandy, France. Eighteen strains of influenza C virus were detected in these samples using a combined tissue culture/RT-PCR diagnostic method. Most patients with influenza C virus infection (13/18) w...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:1997-08-01 00:00:00
abstract::Data on the serological response toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 16 recent reports were analyzed and a high degree of variability was shown. Immunoglobulin M (IgM) responses were either found earlier than IgG, or together with IgG, later than IgG, or were missing. Therefore, clea...
journal_title:Journal of medical virology
pub_type: 杂志文章,评审
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更新日期:2020-07-07 00:00:00
abstract::The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34 persistently infected patients ...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:1995-09-01 00:00:00
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更新日期:1992-02-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1989-02-01 00:00:00