Molecular epidemiology of astroviruses in Japan from 1995 to 1998 by reverse transcription-polymerase chain reaction with serotype-specific primers (1 to 8).

abstract：:The molecular epidemiology of hepatitis A virus (HAV) strains circulating in the St. Petersburg and Karelia regions was studied during 1997-2003. Hepatitis A virus RNA was isolated from both clinical samples (stools or sera) and environmental samples (sewage water). RT-PCR was carried out using different primer pairs ...

journal_title：Journal of medical virology

authors： Davidkin I,Zheleznova N,Jokinen S,Gorchakova O,Broman M,Mukomolov S

更新日期：2007-06-01 00:00:00

abstract：:Human T-cell lymphotropic virus 1 (HTLV-1) is associated with two progressive diseases: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia/lymphoma (ATLL). Although HTLV-1 proviral load (PVL) has been introduced as a risk factor for these diseases' progression, it is not suff...

journal_title：Journal of medical virology

authors： Mozhgani SH,Jaberi N,Rezaee SA,Bustani R,Jazayeri SM,Akbarin MM,Milani S,Tarokhian H,Norouzi M

更新日期：2017-06-01 00:00:00

abstract：:Human metapneumovirus, with two known genotypes named A and B, is associated with mild respiratory symptoms to severe LRTI in children, high-risk adults and the elderly. Rapid and reliable methods of hMPV detection in clinical samples are essential to implement appropriate care, to better understand the pathology of h...

journal_title：Journal of medical virology

authors： Manoha C,Bour JB,Pitoiset C,Darniot M,Aho S,Pothier P

更新日期：2008-01-01 00:00:00

abstract：:The effect of interferon-gamma (IFN-gamma) on dengue virus multiplication in human peripheral blood monocytes was investigated. Enriched monocytes were treated with IFN-gamma and then infected with dengue virus type 2 either directly or in the presence of optimal infection-enhancing levels of antibodies. Pretreatment ...

journal_title：Journal of medical virology

authors： Sittisombut N,Maneekarn N,Kanjanahaluethai A,Kasinrerk W,Viputtikul K,Supawadee J

更新日期：1995-01-01 00:00:00

abstract：:The use of quantitative assays for hepatitis C virus specific antibodies (anti-HCV) as a prognostic marker was evaluated in 31 patients with chronic hepatitis C treated with interferon (IFN). Changes in titers of serum HCV-RNA and anti-HCV antibodies; anti-C11 (anti-core), anti-C100 (anti-NS3), and anti-C7 (anti-NS3) ...

journal_title：Journal of medical virology

authors： Urushihara A,Sodeyama T,Matsumoto A,Tanaka E

更新日期：1994-04-01 00:00:00

abstract：:Cervical cancer development has been mainly associated with persistent human papillomavirus (HPV) infections. However, HPV infection is unlikely to be sufficient to cause cervical cancer, and the contribution of other sexually transmitted infections (STIs) could be the determining factor for cervical lesion-progressio...

journal_title：Journal of medical virology

authors： Magaña-Contreras M,Contreras-Paredes A,Chavez-Blanco A,Lizano M,De la Cruz-Hernandez Y,De la Cruz-Hernandez E

更新日期：2015-12-01 00:00:00

abstract：:We designed experiments to assess the effects of binding of the HSV-2 Fc receptor (FcR) to purified rabbit nonimmune IgG and purified Fc. Purified Fc (75 micrograms) or nonimmune IgG (100 micrograms) when bound to HSV-2 did not reduce infectivity but did protect the virions against thermal inactivation at 37 degrees C...

journal_title：Journal of medical virology

authors： Dowler KW,Veltri RW

更新日期：1984-01-01 00:00:00

abstract：:This was an exploratory study to investigate lamivudine-resistant hepatitis B virus (HBV) strains in selected lamivudine-naïve HBV carriers with and without human immunodeficiency virus (HIV) co-infection in South African patients. Thirty-five lamivudine-naïve HBV infected patients with or without HIV co-infection wer...

journal_title：Journal of medical virology

authors： Selabe SG,Lukhwareni A,Song E,Leeuw YG,Burnett RJ,Mphahlele MJ

更新日期：2007-11-01 00:00:00

abstract：:Hepatitis C virus subtype 3a (HCV-3a) originates from Asia and has spread widely among injecting drug users as well as other patient groups in industrialized countries. HCV subtype 3a infection remains highly prevalent and frequently transmitted in the population of intravenous drug users. The objective of this study ...

journal_title：Journal of medical virology

authors： Morice Y,Cantaloube JF,Beaucourt S,Barbotte L,De Gendt S,Goncales FL,Butterworth L,Cooksley G,Gish RG,Beaugrand M,Fay F,Fay O,Gonzalez JE,Martins RM,Dhumeaux D,Vanderborght B,Stuyver L,Sablon E,de Lamballerie X,Pawl

更新日期：2006-10-01 00:00:00

abstract：:To assess the prevalence of HPV infection in the genital tracts of women with normal PAP smears, a random series of 109 women was reexamined using colposcopy, a further PAP smear, and punch biopsies taken from the cervix (in 33 cases), vagina (212 cases), and anus (20 cases). The biopsy material was examined using rou...

journal_title：Journal of medical virology

authors： Syrjänen S,Saastamoinen J,Chang FJ,Ji HX,Syrjänen K

更新日期：1990-08-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) can lead to a massive cytokine release. The use of the anti-interleukin-6 receptor monoclonal antibody tocilizumab (TCZ) has been proposed in this hyperinflammatory phase, although supporting evidence is limited. We retrospectively analyzed 88 consecutive patients with COVID-19 pneu...

journal_title：Journal of medical virology

authors： Fernández-Ruiz M,López-Medrano F,Pérez-Jacoiste Asín MA,Maestro de la Calle G,Bueno H,Caro-Teller JM,Catalán M,de la Calle C,García-García R,Gómez C,Laguna-Goya R,Lizasoáin M,Martínez-López J,Origüen J,Pablos JL,Ripoll M,

更新日期：2021-02-01 00:00:00

abstract：:The current Agence Nationale de Recherche sur le SIDA (ANRS)/International AIDS Society (IAS) algorithm predicts resistance to etravirine for viruses harboring >/=3 mutations from a list of 13 reverse transcriptase (RT) mutations. Two weighted algorithms, best correlated with fold changes to etravirine, have been desc...

journal_title：Journal of medical virology

authors： Cotte L,Trabaud MA,Tardy JC,Brochier C,Gilibert RP,Miailhes P,Trépo C,André P

更新日期：2009-04-01 00:00:00

abstract：:Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV-DNA was detected in the CSF of 13 patients with HSE, including 5 neonates. A restriction profile of th...

journal_title：Journal of medical virology

authors： Ando Y,Kimura H,Miwata H,Kudo T,Shibata M,Morishima T

更新日期：1993-10-01 00:00:00

abstract：:Enterovirus (EV) infections are common. There are more than 60 known serotypes, and each has different epidemiologic or medical importance. Over 700 physicians from 75% of basic administrative units of Taiwan participated in the "Sentinel Physician Surveillance of Infectious Disease" and reported weekly to the Center ...

journal_title：Journal of medical virology

authors： Tseng FC,Huang HC,Chi CY,Lin TL,Liu CC,Jian JW,Hsu LC,Wu HS,Yang JY,Chang YW,Wang HC,Hsu YW,Su IJ,Wang JR,CDC-Taiwan Virology Reference Laboratories and Sentinel Physician Network.

更新日期：2007-12-01 00:00:00

abstract：:Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...

journal_title：Journal of medical virology

authors： Dubey RC,Alam NB,Gaur R

更新日期：2020-12-24 00:00:00

abstract：:Human parechoviruses (HPeV) are associated with central nervous system (CNS) infections and sepsis-like illnesses. However, data from China are not available. The aim of this study was to determine the prevalence, age, and seasonal distributions and genotypes of HPeV infections in children with CNS related disease in ...

journal_title：Journal of medical virology

authors： Zhong H,Lin Y,Su L,Cao L,Xu M,Xu J

更新日期：2013-02-01 00:00:00

abstract：:The evidence on genotype-specific risk in women infected with human papillomavirus (HPV) with normal cytology and the importance of the distinction of high-risk (HR)-HPV genotypes in the management of low-grade lesions suggest that the distinction of HR-HPV genotypes has the potential to improve the follow-up of patie...

journal_title：Journal of medical virology

authors： Venturoli S,Ambretti S,Cricca M,Leo E,Costa S,Musiani M,Zerbini M

更新日期：2008-08-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To further understand inflammation in the airways following infection, we tested for the presence of matrix metalloproteinases (MMP) and natural tissue inhibitors ...

journal_title：Journal of medical virology

authors： Elliott MB,Welliver RC Sr,Laughlin TS,Pryharski KS,LaPierre NA,Chen T,Souza V,Terio NB,Hancock GE

更新日期：2007-04-01 00:00:00

abstract：:Human papillomavirus (HPV) RNA levels may be a more sensitive early indicator of predisposition to carcinogenesis than DNA levels. We evaluated whether levels of HPV-16 and HPV-18 DNA and messenger RNA (mRNA) in newly detected infections are associated with cervical lesion development. Female university students were ...

journal_title：Journal of medical virology

authors： Winer RL,Harris TG,Xi LF,Jansen KU,Hughes JP,Feng Q,Welebob C,Ho J,Lee SK,Carter JJ,Galloway DA,Kiviat NB,Koutsky LA

更新日期：2009-04-01 00:00:00

abstract：:The X gene product of human hepatitis B virus, HBx, transactivates the expression of viral and cellular genes through a wide variety of cis elements, including the nuclear factor for IL-6 (NF-IL6) binding sites, although HBx does not appear to bind DNA directly. We previously reported that HBx transactivated the inter...

journal_title：Journal of medical virology

authors： Ohno H,Kaneko S,Lin Y,Kobayashi K,Murakami S

更新日期：1999-05-01 00:00:00

abstract：:Hepatitis B virus (HBV) genotypes impact treatment outcomes and disease progression. The current genotyping methods have limitations in patients with low HBV viral load. In this study, a more sensitive assay has been developed for determining the HBV genotype in HBV DNA suppressed patients. Fifty-five serum samples fr...

journal_title：Journal of medical virology

authors： Liu Y,May L,Liu X,Martin R,Svarovskaia E,Gaggar A,Mo H,Feierbach B

更新日期：2020-07-01 00:00:00

abstract：:Enterovirus 68 (EV-D68) was associated with mild to severe respiratory infections. In the last 4 years, circulation of different EV-D68 strains has been documented worldwide. In this study, the phylogenetic characterization of nine EV-D68 strains identified in patients in the 2010-2012 period and 12 additional EV-D68 ...

journal_title：Journal of medical virology

authors： Piralla A,Girello A,Grignani M,Gozalo-Margüello M,Marchi A,Marseglia G,Baldanti F

更新日期：2014-09-01 00:00:00

abstract：:Mutations of the precore region of hepatitis B virus (HBV) genome have been associated with fulminant and severe chronic hepatitis. However uncertainty remains about the clinical significance and transmissibility of these mutant strains. A point mutation assay (PMA) was developed to identify qualitatively and quantita...

journal_title：Journal of medical virology

authors： Hawkins AE,Gilson RJ,Beath SV,Boxall EH,Kelly DA,Tedder RS,Weller IV

更新日期：1994-09-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:To characterize cytotoxic T lymphocytes (CTLs) that appeared in circulation during lamivudine therapy, we analyzed HBV-specific CTLs using HLA-A24 tetramer and HBcAg-specific Th1 cells in patients receiving lamivudine therapy. Six patients (HLA-A24(+)) with chronic hepatitis B, six patients (HLA-A24(-)) with chronic h...

journal_title：Journal of medical virology

authors： Kondo Y,Asabe S,Kobayashi K,Shiina M,Niitsuma H,Ueno Y,Kobayashi T,Shimosegawa T

更新日期：2004-11-01 00:00:00

abstract：:Influenza epidemic is an important cause of severe illness in the elderly. Age-dependent morbidity of influenza in the elderly is associated with weakened immunity. The baseline age-related memory T cell activity in Chinese persons who are exposed to influenza virus through natural infection, are associated with the p...

journal_title：Journal of medical virology

authors： Jia N,Li C,Liu YX,Richardus JH,Feng D,Yang H,Dang RL,Ma YH,Xu XN,Cao WC

更新日期：2009-08-01 00:00:00

abstract：:This is an audit of a new technique to improve the colposcopy service. Samples were tested for high risk HPV DNA using Digene Hybrid Capture II. Sixty-four percent of the sampled women under 30 had detectable high risk HPV DNA, decreasing to 44% in 30--39 year olds and to 27% in women over 40. High risk HPV prevalence...

journal_title：Journal of medical virology

authors： Perrons C,Brink N,Jalal H,Watts P,Jelley R

更新日期：2005-08-01 00:00:00

abstract：:In vitro, beta-herpesviruses can stimulate or inhibit HIV replication under particular circumstances. In order to investigate the effects of beta-herpesvirus infection on HIV replication and vice versa at an organ level, we determined the quantitative relationships between cytomegalovirus (CMV), human herpesviruses (H...

journal_title：Journal of medical virology

authors： Emery VC,Atkins MC,Bowen EF,Clark DA,Johnson MA,Kidd IM,McLaughlin JE,Phillips AN,Strappe PM,Griffiths PD

更新日期：1999-03-01 00:00:00

abstract：:Nasal washings were collected from 27 normal adults during 38 naturally acquired colds. The washings were exhaustively tested using tissue cultures, organ cultures and electron microscopy. Washings yielding no identifiable agent were inoculated into human volunteers, and further specimens obtained from the latter were...

journal_title：Journal of medical virology

authors： Larson HE,Reed SE,Tyrrell DA

更新日期：1980-01-01 00:00:00