Epidemiology of Varicella-Zoster Virus in England and Wales.

Abstract:

:Many countries are studying currently the possibility of mass vaccination against varicella. The objective of this study was to provide a complete picture of the pre-vaccine epidemiology of the Varicella-Zoster Virus in England and Wales to aid in the design of immunisation programs. Population-based data including general practitioner sentinel surveillance, hospitalisation data, and death certificates from England and Wales were analysed. The average incidence rates for varicella and zoster between 1991 and 2000 were 1,291 and 373 per 100,000 years, respectively. Overall hospitalisation rates were equal for varicella and zoster (4.5 vs. 4.4 hospitalisation per 100,000 population) with 5 and 8%, respectively, having underlying immunosuppressive conditions. The age-specific proportion of cases hospitalised and length of stay were similar between the two diseases. However, the overall burden of disease is considerably higher for zoster. The number of inpatient days and case-fatality due to zoster are roughly 4 to 6 times greater than for varicella (11 vs. 3 days and 25 vs. 4 deaths per 100,000 case). These results provide base-line estimates should mass varicella vaccination be introduced in England and Wales.

journal_name

J Med Virol

authors

Brisson M,Edmunds WJ

doi

10.1002/jmv.10313

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

S9-14

eissn

0146-6615

issn

1096-9071

journal_volume

70 Suppl 1

pub_type

杂志文章
  • Real-time PCR for detection and quantitation of hepatitis B virus DNA.

    abstract::A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2027

    authors: Chen RW,Piiparinen H,Seppänen M,Koskela P,Sarna S,Lappalainen M

    更新日期:2001-10-01 00:00:00

  • Rhinovirus frequently detected in elderly adults attending an emergency department.

    abstract::The general aim was to investigate the burden of respiratory virus illness in a hospital emergency department, during two different epidemic seasons. Consecutive patients attending an emergency department during two study periods (February/March 2009 and 2010) were enrolled using broad inclusion criteria (fever/preced...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22205

    authors: Pierangeli A,Scagnolari C,Selvaggi C,Verzaro S,Spina MT,Bresciani E,Antonelli G,Bertazzoni G

    更新日期:2011-11-01 00:00:00

  • Prevalence of delta agent among Chinese in Taiwan and Los Angeles.

    abstract::The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890140106

    authors: Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

    更新日期:1984-01-01 00:00:00

  • Intestinal immunity to poliovirus develops only after repeated infections in monkeys.

    abstract::To establish gut immunity in monkeys to polio-virus type 1, we fed four juvenile bonnet monkeys (Macaca radiata) with 100 median infectious doses of the Mahoney strain of virus. The duration of viral shedding in the throat and faeces and the titre of virus in faeces were measured. Eighteen days after the last monkey s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890270208

    authors: Selvakumar R,John TJ

    更新日期:1989-02-01 00:00:00

  • Use of a generic polymerase chain reaction assay detecting human T-lymphotropic virus (HTLV) types I, II and divergent simian strains in the evaluation of individuals with indeterminate HTLV serology.

    abstract::In countries with a low prevalence of human T-lymphotropic virus (HTLV) infection, indeterminate HTLV serologies are a major problem in blood bank screening because of the uncertainties about infection in these cases. The recent discovery of two new types of simian T-lymphotropic viruses (STLV), which give an HTLV-ind...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Vandamme AM,Van Laethem K,Liu HF,Van Brussel M,Delaporte E,de Castro Costa CM,Fleischer C,Taylor G,Bertazzoni U,Desmyter J,Goubau P

    更新日期:1997-05-01 00:00:00

  • Poliovirus serotype 2 and coxsackievirus A promote the natural recombination of poliovirus.

    abstract::Poliovirus (PV) is a member of the species Enterovirus C (EV-C), which may cause irreversible paralysis and death. So, for the purpose of analyzing the evolution of PV2 to help in eradicating PVs globally, a recombination analysis was performed to verify all viral genomes of EV-C, and we found 13 putative recombinatio...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25620

    authors: Qian Y,Pu X,Yu Y,Yu X,Kong L,Liu L,Wang H,Shen H

    更新日期:2020-03-01 00:00:00

  • Analysis of clinical and virological factors associated with response to alpha interferon therapy in chronic hepatitis C.

    abstract::Interferon alpha (IFN-alpha) therapy is currently the treatment of choice for chronic hepatitis C (HCV) infection, but it fails to achieve a sustained response in approximately 75% of those treated. The factors which determine whether or not an individual will respond to IFN-alpha are uncertain, although a number of p...

    journal_title:Journal of medical virology

    pub_type: 临床试验,杂志文章

    doi:10.1002/jmv.1890450320

    authors: Garson JA,Brillanti S,Whitby K,Foli M,Deaville R,Masci C,Miglioli M,Barbara L

    更新日期:1995-03-01 00:00:00

  • Viral genotypes and response to interferon in patients with acute prolonged hepatitis B virus infection of adulthood in Japan.

    abstract::Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10239

    authors: Kobayashi M,Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Suzuki F,Akuta N,Someya T,Matsuda M,Sato J,Takagi K,Miyakawa Y,Kumada H

    更新日期:2002-12-01 00:00:00

  • The difference in mortality between adult patients with laboratory documented Influenza A and B, a single centre retrospective observational study.

    abstract:BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26600

    authors: Mabayoje DA,Cutino-Moguel T,Haigh J,Wilks M,Welch CA,Melzer M

    更新日期:2020-10-15 00:00:00

  • Molecular epidemiology of rotavirus gastroenteritis in Japan during 2014-2015: Characterization of re-emerging G2P[4] after rotavirus vaccine introduction.

    abstract::Rotavirus vaccines have been available in Japan since 2011. This study conducted to monitor the trend of group A rotavirus (RVA) genotypes 3 years after vaccine introduction. A total of, 539 fecal samples were collected from children with acute gastroenteritis in six regions during July 2014-June 2015. Among them, 178...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25067

    authors: Khandoker N,Thongprachum A,Takanashi S,Okitsu S,Nishimura S,Kikuta H,Yamamoto A,Sugita K,Baba T,Kobayashi M,Hayakawa S,Mizuguchi M,Ushijima H

    更新日期:2018-06-01 00:00:00

  • Hepatitis C virus infection of mononuclear cells from peripheral blood and liver infiltrates in chronically infected patients.

    abstract::The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34 persistently infected patients ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470112

    authors: Zignego AL,De Carli M,Monti M,Careccia G,La Villa G,Giannini C,D'Elios MM,Del Prete G,Gentilini P

    更新日期:1995-09-01 00:00:00

  • Response to antiviral treatment in patients infected with hepatitis B virus genotypes E-H.

    abstract::No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by di...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21588

    authors: Erhardt A,Göbel T,Ludwig A,Lau GK,Marcellin P,van Bömmel F,Heinzel-Pleines U,Adams O,Häussinger D

    更新日期:2009-10-01 00:00:00

  • Molecular epidemiology of hepatitis A in St. Petersburg, Russia, 1997-2003.

    abstract::The molecular epidemiology of hepatitis A virus (HAV) strains circulating in the St. Petersburg and Karelia regions was studied during 1997-2003. Hepatitis A virus RNA was isolated from both clinical samples (stools or sera) and environmental samples (sewage water). RT-PCR was carried out using different primer pairs ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20843

    authors: Davidkin I,Zheleznova N,Jokinen S,Gorchakova O,Broman M,Mukomolov S

    更新日期:2007-06-01 00:00:00

  • Genotyping of acute hepatitis a virus isolates from China, 2003-2008.

    abstract::Hepatitis A virus (HAV) is usually transmitted by an oral-fecal route and is prevalent not only in developing countries but also in developed countries. In the present study, the phylogenetic characterization of the VP1/2A junction region (321 nucleotides) of China HAV isolates was examined. Anti-HAV IgM-positive seru...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22086

    authors: Cao J,Bi S,Meng Q,Shen L,Zheng H,Zhang Y

    更新日期:2011-07-01 00:00:00

  • Significance of postnatal mother-to-child transmission of human T-lymphotropic virus type-I on the development of adult T-cell leukemia/lymphoma.

    abstract::In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890200307

    authors: Sugiyama H,Doi H,Yamaguchi K,Tsuji Y,Miyamoto T,Hino S

    更新日期:1986-11-01 00:00:00

  • Seroprevalence of markers of viral hepatitis in Yemeni healthcare workers.

    abstract::The seroprevalence of viral hepatitis in healthcare workers has important public health implications. To assess the risk factors for the acquisition of viral hepatitis in an unvaccinated cohort from an hyperendemic region, 567 healthcare workers from a large hospital in the capital of the Republic of Yemen were interv...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20126

    authors: Shidrawi R,Ali Al-Huraibi M,Ahmad Al-Haimi M,Dayton R,Murray-Lyon IM

    更新日期:2004-08-01 00:00:00

  • Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: analysis of sentinel physician surveillance data.

    abstract::Enterovirus (EV) infections are common. There are more than 60 known serotypes, and each has different epidemiologic or medical importance. Over 700 physicians from 75% of basic administrative units of Taiwan participated in the "Sentinel Physician Surveillance of Infectious Disease" and reported weekly to the Center ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21006

    authors: Tseng FC,Huang HC,Chi CY,Lin TL,Liu CC,Jian JW,Hsu LC,Wu HS,Yang JY,Chang YW,Wang HC,Hsu YW,Su IJ,Wang JR,CDC-Taiwan Virology Reference Laboratories and Sentinel Physician Network.

    更新日期:2007-12-01 00:00:00

  • Seroprevalence of Kaposi's sarcoma-associated herpesvirus among men who have sex with men in Japan.

    abstract::Kaposi's sarcoma-associated herpesvirus (KSHV), the etiologic agent of Kaposi's sarcoma, causes malignancies frequently in patients with acquired immunodeficiency syndrome. In the United States and Europe, KSHV infection is common among men who have sex with men. However, the seroprevalence of KSHV among men who have ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23558

    authors: Katano H,Yokomaku Y,Fukumoto H,Kanno T,Nakayama T,Shingae A,Sugiura W,Ichikawa S,Yasuoka A

    更新日期:2013-06-01 00:00:00

  • Patterns of serum type 1 and type 2 immune markers in healthy carriers of HTLV-I.

    abstract::Type 1 immunity appears to be diminished in healthy Japanese carriers of human T-lymphotropic virus type I (HTLV-I), but type 2 status remains undetermined. To further examine the subclinical effect of HTLV-I on host immunity, we measured serum antibodies to the Epstein-Barr virus (EBV) in 415 healthy Japanese adults ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20633

    authors: Birmann BM,Mueller NE,Okayama A,Hsieh CC,Tsubouchi H,Harn D,Stuver SO

    更新日期:2006-06-01 00:00:00

  • Prevalence of CMV antibodies among women of childbearing age in different social environments in southern Israel.

    abstract::The prevalence rate of IgG antibodies to cytomegalovirus (CMV) was determined in a sample of 567 women of childbearing age in the southern part of Israel by the immunoperoxidase assay to membrane antigen (IPAMA) technique. Urban Jewish women of Afro-Asian origin showed significantly higher rates of seropositivity than...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890240104

    authors: Urkin J,Sarov B,Naggan L,Haikin H,Sarov I

    更新日期:1988-01-01 00:00:00

  • Hepatitis B virus genotype D strains from Estonia share sequence similarity with strains from Siberia and may specify ayw4.

    abstract::The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20169

    authors: Tallo T,Norder H,Tefanova V,Krispin T,Priimägi L,Mukomolov S,Mikhailov M,Magnius LO

    更新日期:2004-10-01 00:00:00

  • The role of autophagy in human cytomegalovirus IE2 expression.

    abstract::The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26357

    authors: Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

    更新日期:2020-07-25 00:00:00

  • Human cytomegalovirus (HCMV)-specific T cell but not neutralizing or IgG binding antibody responses to glycoprotein complexes gB, gHgLgO, and pUL128L correlate with protection against high HCMV viral load reactivation in solid-organ transplant recipients.

    abstract::Immune correlates of protection against human cytomegalovirus (HCMV) infection are still debated. This study aimed to investigate which arm of the immune response plays a major role in protection against HCMV infection in kidney transplant recipients (n = 40) and heart transplant recipients (n = 12). Overall, patients...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25225

    authors: Lilleri D,Zelini P,Fornara C,Zavaglio F,Rampino T,Perez L,Gabanti E,Gerna G

    更新日期:2018-10-01 00:00:00

  • Intricacies in characterizing positivity in pooled sample testing for SARS-CoV-2.

    abstract:OBJECTIVE:The unprecedented demand for testing for the ongoing coronavirus disease-2019 (COVID-19) pandemic caused by SARS-CoV-2 has led to an acute shortage and limited availability of test reagents for which pooling of samples has been recommended in areas with low prevalence. Considering the possibility of dilution ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26618

    authors: Mohanty S,Ravindra A,Gupta K,Hallur V,Behera B,Mahaptra A,Saha S,Ranjan J,Payal P,Mohanty M,Rath S,Mishra B

    更新日期:2020-10-21 00:00:00

  • Evidence for persistence of parvovirus B19 DNA in livers of adults.

    abstract::Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2047

    authors: Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

    更新日期:2001-10-01 00:00:00

  • Development of a sensitive assay for the measurement of antibodies against heat shock protein binding protein 1 (HspBP1): increased levels of anti-HspBP1 IgG are prevalent in HIV infected subjects.

    abstract::The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the extracellular environment. Hsp70 and antibodies against Hsp70 have been reported in human serum. Recent evidence has shown that Hsp70 antibodies are elevated in HIV in...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20384

    authors: Papp D,Prohászka Z,Kocsis J,Füst G,Bánhegyi D,Raynes DA,Guerriero V

    更新日期:2005-08-01 00:00:00

  • Hemagglutinin-neuraminidase sequence and phylogenetic analyses of mumps virus isolates from a vaccinated population in Singapore.

    abstract::During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isola...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10393

    authors: Lim CS,Chan KP,Goh KT,Chow VT

    更新日期:2003-06-01 00:00:00

  • Laboratory diagnosis and surveillance of human respiratory viruses by PCR in Victoria, Australia, 2002-2003.

    abstract::Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20246

    authors: Druce J,Tran T,Kelly H,Kaye M,Chibo D,Kostecki R,Amiri A,Catton M,Birch C

    更新日期:2005-01-01 00:00:00

  • Thermostabilization of Inoue-Melnick virus by salt.

    abstract::Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of I...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890200203

    authors: Nishibe Y,Inoue YK,Melnick JL

    更新日期:1986-10-01 00:00:00

  • High rate of missed HIV infections in individuals with indeterminate or negative HIV western blots based on current HIV testing algorithm in China.

    abstract::It remains unclear if China's current HIV antibody testing algorithm misses a substantial number of HIV infected individuals. Of 196 specimens with indeterminate or negative results on HIV western blot (WB) retrospectively examined by HIV-1 nucleic acid test (NAT), 67.57% (75/111) of indeterminate WB samples, and 16.4...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24490

    authors: Liu MQ,Zhu ZR,Kong WH,Tang L,Peng JS,Wang X,Xu J,Schilling RF,Cai T,Zhou W

    更新日期:2016-08-01 00:00:00