Characterization of Epstein-Barr virus (EBV) BZLF1 gene promoter variants and comparison of cellular gene expression profiles in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated hemophagocytic lymphohistioc

abstract：:A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

journal_title：Journal of medical virology

authors： Tay N,Chan SH,Ren EC

更新日期：1990-04-01 00:00:00

abstract：:The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...

journal_title：Journal of medical virology

authors： Ye Q,Wang B,Mao J,Fu J,Shang S,Shu Q,Zhang T

更新日期：2020-07-01 00:00:00

abstract：:In mid-December 2019, a disease caused by infection with severe acute respiratory syndrome coronavirus-2, which began in Wuhan, China, has spread throughout the country and many countries around the world. The number of children with coronavirus disease-2019 (COVID-19) has also increased significantly. Although inform...

journal_title：Journal of medical virology

authors： She J,Liu L,Liu W

更新日期：2020-07-01 00:00:00

abstract：:Knowledge of the antigenic diversity of rotaviruses circulating in a region should be acquired before introducing a rotavirus vaccine. In a collection of 151 rotavirus-positive samples from Mendoza, Argentina, strain diversity was evaluated utilizing G-typing monoclonal antibodies (MAbs), reverse-transcriptase-polymer...

journal_title：Journal of medical virology

authors： Espul C,Cuello H,Martinez N,Centorbi O,O'Ryan M,Jackson L,Campos F,Matson DO

更新日期：2000-08-01 00:00:00

abstract：:Natural history of anal intraepithelial neoplasia and anal cancer is not fully understood. Factors associated with cytological abnormalities and predictors of progression to high-grade anal intraepithelial neoplasia still deserve investigation. The aim of this cross-sectional study was to assess the prevalence of HPV ...

journal_title：Journal of medical virology

authors： Tamalet C,Obry-Roguet V,Ressiot E,Bregigeon S,Del Grande J,Poizot-Martin I

更新日期：2014-03-01 00:00:00

abstract：:The replication strategy of a human serotype 1 rotavirus, adapted to rapid growth in CV-1 cells, was investigated. A single cycle growth curve revealed eclipse and latent periods of 3 and 4 hours, respectively. Although the extent of reduction of host cell protein synthesis was directly related to the multiplicity of ...

journal_title：Journal of medical virology

authors： Heath RL,Birch CJ

更新日期：1988-05-01 00:00:00

abstract：:The oncoprotein Tax was characterized genetically from a large cohort of human T-cell lymphotropic virus type 1 (HTLV-1) seropositive individuals from the most endemic region of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 infection in Argentina, the province of San Salvador de Jujuy....

journal_title：Journal of medical virology

authors： Iñiguez AM,Gastaldello R,Otsuki K,Balangero M,Carvalho Costa F,Remondegui C,Paula Vicente AC,Gallego S

更新日期：2010-08-01 00:00:00

abstract：:It is need for development of new means against influenza virus due to the lack of efficacy of available therapeutic strategies. In previous research, 1,8-cineol exert its inhibition of nuclear factor (NF)-κB, the main regulator of cytokine and chemokine production in influenza, and anti-inflammatory activity. These f...

journal_title：Journal of medical virology

authors： Lai YN,Li Y,Fu LC,Zhao F,Liu N,Zhang FX,Xu PP

更新日期：2017-07-01 00:00:00

abstract：:Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...

journal_title：Journal of medical virology

authors： Sullivan SG,Komadina N,Grant K,Jelley L,Papadakis G,Kelly H

更新日期：2014-06-01 00:00:00

abstract：:A method for the absorption of false radioimmunoassay (RIA) IgM titres against herpes simplex virus (HSV) and cytomegalovirus (CMV) is presented. The serum specimens were absorbed by a mixture of protein A-Sepharose and protein A-Sepharose saturated with normal human gamma globulin (PAS/IgG). The detection of rheumato...

journal_title：Journal of medical virology

authors： Torfason EG,Diderholm H

更新日期：1982-01-01 00:00:00

abstract：:Norovirus is one of the major causes of outbreaks and sporadic cases of acute gastroenteritis in young children worldwide. Obtaining local baseline information regarding this virus is important for developing and evaluating prevention strategies of norovirus transmission in children. The age, seasonal distribution and...

journal_title：Journal of medical virology

authors： Xu J,Yang Y,Sun J,Ding Y

更新日期：2009-10-01 00:00:00

abstract：:Influenza A/H3N2 viruses are associated with severe epidemics. Antiviral resistance and continued antigenic drift are the major concerns regarding prophylaxis and treatment of influenza. The objectives of this study were to investigate the prevalence and frequency of antiviral drug resistance in influenza A/H3N2 virus...

journal_title：Journal of medical virology

authors： Cai J,Wang X,Zhao B,Yao W,Wang X,Zhu Q,Zeng M

更新日期：2014-06-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:Described for the first time in 1986, Parvovirus B19 (B19V) infection in kidney transplant recipients remains little-known and probably underestimated. The aims of this study were to establish B19V infection frequency during the first year after kidney transplant and to determine predisposing factors and manifestation...

journal_title：Journal of medical virology

authors： Porignaux R,Vuiblet V,Barbe C,Nguyen Y,Lavaud S,Toupance O,Andréoletti L,Rieu P,Lévêque N

更新日期：2013-06-01 00:00:00

abstract：:The rapid emergence of coronavirus disease 2019 (COVID-19) has necessitated the implementation of diverse pandemic control strategies throughout the world. To effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that di...

journal_title：Journal of medical virology

authors： Zheng Z,Yao Z,Wu K,Zheng J

更新日期：2020-11-01 00:00:00

abstract：:Human parainfluenza virus 3 (HPIV-3) is a leading cause of respiratory disease in children worldwide. Previous sequence analyses of the entire virus genome, among different HPIV-3 strains, demonstrated that HN is the most variable gene. There is a dearth of data on HPIV-3 strains circulating in Saudi Arabia. In this r...

journal_title：Journal of medical virology

authors： Almajhdi FN,Alshaman MS,Amer HM

更新日期：2012-08-01 00:00:00

abstract：:The human cytomegalovirus (HCMV), a member of the Herpesviridae, is the most frequent cause of congenital virus infections and a major cause of morbidity and mortality in immunocompromised patients. Due to the lack of an appropriate animal model, insight into the pathogenesis of HCMV infections originates primarily fr...

journal_title：Journal of medical virology

authors： Bissinger AL,Sinzger C,Kaiserling E,Jahn G

更新日期：2002-06-01 00:00:00

abstract：:In the present study the reactivity of IgG and IgM antibodies against HSV-1 structural and nonstructural proteins was analyzed by Western blot analysis (WBA) and radioimmunoprecipitation followed by polyacrylamide gel electrophoresis (RIPA-PAGE). It was demonstrated that IgM and IgG antibodies were directed against vi...

journal_title：Journal of medical virology

authors： Kühn JE,Dunkler G,Munk K,Braun RW

更新日期：1987-10-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

journal_title：Journal of medical virology

authors： Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

更新日期：2009-08-01 00:00:00

abstract：:Previously, it was reported that productive viral infection, viral protein synthesis, and viral RNA replication of respiratory syncytial virus (RSV) operated efficiently in two human epithelial cell lines (HEp-2 and A549), but not in a human mast-cell line, HMC-1. Based on these observations, it was hypothesized that ...

journal_title：Journal of medical virology

authors： Shirato K,Ujike M,Kawase M,Matsuyama S

更新日期：2012-02-01 00:00:00

abstract：:Phleboviruses are a large and widespread group of viruses that are transmitted by arthropods. Toscana virus is one of the principal agents that causes meningitis in humans during the summer in Italy and, possibly, in other Mediterranean countries. Rift Valley Fever virus can cause serious illness in both animals and h...

journal_title：Journal of medical virology

authors： Sánchez-Seco MP,Echevarría JM,Hernández L,Estévez D,Navarro-Marí JM,Tenorio A

更新日期：2003-09-01 00:00:00

abstract：:Nucleotide sequences of the hypervariable region (HVR) of the E2/NS1 gene of hepatitis C virus (HCV), which are now thought to contain epitopes for neutralizing antibodies, were compared between antibody-bound HCV and free HCV in a patient with type II cryoglobulinemia. Antibody-bound HCV was immunoprecipitated with a...

journal_title：Journal of medical virology

authors： Kurosaki M,Enomoto N,Nouchi T,Sakuma I,Marumo F,Sato C

更新日期：1995-08-01 00:00:00

abstract：:Dengue, caused by any of the four types of Dengue virus (DENV) is the most important arbovirus in the world. In this study we performed a molecular surveillance of dengue during the greatest dengue outbreak that took place in Divinópolis, Minas Gerais state, Southeast Brazil, in 2013. Samples from 100 patients with cl...

journal_title：Journal of medical virology

authors： Dutra KR,Drumond BP,de Rezende IM,Nogueira ML,de Oliveira Lopes D,Calzavara Silva CE,Siqueira Ferreira JM,Dos Santos LL

更新日期：2017-06-01 00:00:00

abstract：:Hantaviruses is an emerging infectious disease. Although HCPS has been reported in several regions of Brazil, more cases of HCPS have recently been reported in Minas Gerais than in any other state. In 2009, we analyzed 27 samples presenting antibodies against hantaviruses. These samples originated from 688 symptomatic...

journal_title：Journal of medical virology

authors： de Araujo J,Duré AI,Negrão R,Ometto T,Thomazelli LM,Durigon EL

更新日期：2015-05-01 00:00:00

abstract：:Rabbit antibodies produced by immunization with complete hepatitis A virions (HAV) recognized all the viral structural proteins and neutralized HAV infectivity in cell culture. Rabbit antibodies to chromatographically purified individual viral proteins and to synthetic peptides representing epitopes on the structural ...

journal_title：Journal of medical virology

authors： Gauss-Müller V,Deinhardt F

更新日期：1988-02-01 00:00:00

abstract：:This study analyzed the genotype distribution and frequency of lamivudine (LAM) and tenofovir (TDF) resistance mutations in a group of patients co-infected with HIV and hepatitis B virus (HBV). A cross-sectional study of 847 patients with HIV was conducted. Patients provided blood samples for HBsAg detection. The load...

journal_title：Journal of medical virology

authors： Mendes-Correa MC,Pinho JR,Locarnini S,Yuen L,Sitnik R,Santana RA,Gomes-Gouvêa MS,Leite OM,Martins LG,Silva MH,Gianini RJ,Uip DE

更新日期：2010-09-01 00:00:00

abstract：:Nasopharyngeal carcinoma is closely associated with Epstein-Barr virus (EBV) and the EBV encoded latent membrane protein-1 expression (LMP1) is commonly found in the tumour cells. LMP1 has been shown to be involved in modulation of cell growth in B cells but the biological properties of LMP1 expression in nasopharynge...

journal_title：Journal of medical virology

authors： Liu Y,Wang X,Lo AK,Wong YC,Cheung AL,Tsao SW

更新日期：2002-01-01 00:00:00

abstract：:The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...

journal_title：Journal of medical virology

authors： Cabana M,Clotet B,Martínez MA

更新日期：1999-12-01 00:00:00

abstract：:A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells, herpesvirus nucle...

journal_title：Journal of medical virology

authors： Arao Y,Soushi S,Sato Y,Moriishi E,Ando Y,Yamada M,Padilla J,Uno F,Nii S,Kurata T

更新日期：1997-10-01 00:00:00