Parenteral antischistosomal therapy: a potential risk factor for hepatitis B infection.

Abstract:

:To study the association between hepatitis B and schistosomiasis, 1,234 Egyptian males, ages 18 to 24, were interviewed, examined, and tested for Schistosoma mansoni infection and HBsAg. Sera from 91 (7.4%) of the study subjects were positive for HBsAg, and S. mansoni was found in the stools of 26.3%. There was no correlation between S. mansoni infection, with or without hepatosplenomegaly, or a history of schistosomiasis, and HBsAg. An association was found between HBsAg positivity and a previous history of parenteral antischistosomal therapy (P less than 0.01). The results of the study indicate that parenteral therapy for schistosomiasis may be a risk factor for hepatitis B antigenemia. Further studies are indicated to determine the importance of parenteral therapy in the transmission of hepatitis B.

journal_name

J Med Virol

authors

Hyams KC,Mansour MM,Massoud A,Dunn MA

doi

10.1002/jmv.1890230203

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

109-14

issue

2

eissn

0146-6615

issn

1096-9071

journal_volume

23

pub_type

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