Genital herpes: natural history and treatment of acute episodes.

abstract：:GB virus C (GBV-C) is related to hepatitis C virus (HCV) and has a similar genomic structure. Some predictors for the efficacy of interferon (IFN) therapy on HCV have been reported: genotype, viral load, IFN dose, and the amino acid substitutions in the NS5A region, designated as the interferon sensitivity determining...

journal_title：Journal of medical virology

authors： Kato T,Mizokami M,Orito E,Ohba K,Nakano T,Kondo Y,Tanaka Y,Ueda R,Mukaide M,Yasuda K,Iino S

更新日期：1999-04-01 00:00:00

abstract：:Because Junin virus (JV) experimental encephalitis of mice and rats is characterized by mild histopathological changes that do not seem to justify per se lethality after intracerebral infection, such a murine model seems adequate to investigate the potential role of inducible nitric oxide synthase (iNOS) as a pathogen...

journal_title：Journal of medical virology

authors： Gómez RM,Yep A,Schattner M,Berría MI

更新日期：2003-01-01 00:00:00

abstract：:A highly sensitive two-step polymerase chain reaction (PCR) method was evaluated for detection of human immunodeficiency virus type 1 (HIV-1) DNA in clinical specimens. The product resulting from the first amplification reaction is used as the template for the second PCR with an internal (nested) primer pair. Even whe...

journal_title：Journal of medical virology

authors： Zazzi M,Romano L,Brasini A,Valensin PE

更新日期：1992-11-01 00:00:00

abstract：:B-cells play an important role in defending children against various infections. In view of scare data, we undertook this prospective cohort study to describe B cell compartment in HIV infected children (<5 years of age) and the effect of HAART on B cell subpopulations. HIV infected children (<5 years) from Pediatric ...

journal_title：Journal of medical virology

authors： Singh R,Mukherjee A,Singla M,Vajpayee M,Negi N,Kabra SK,Lodha R,Das BK

更新日期：2018-07-01 00:00:00

abstract：:The objectives of this study were to evaluate the reliability of herpes simplex virus (HSV) PCR testing in cerebrospinal fluid (CSF) for the detection of herpes simplex encephalitis. This was done by examining retrospectively the clinical follow-up of a large group of patients tested routinely by HSV-PCR. In addition,...

journal_title：Journal of medical virology

authors： Puchhammer-Stöckl E,Presterl E,Croÿ C,Aberle S,Popow-Kraupp T,Kundi M,Hofmann H,Wenninger U,Gödl I

更新日期：2001-08-01 00:00:00

abstract：:Treatment with biological drugs is associated with increased susceptibility to viral infections. Reactivation of JC virus (JCV) and human cytomegalovirus (HCMV) in adults after therapy has been documented. The long-term effects of biological and conventional therapy on human herpesviruses and polyomaviruses infections...

journal_title：Journal of medical virology

authors： Comar M,Delbue S,Lepore L,Martelossi S,Radillo O,Ronfani L,D'Agaro P,Ferrante P

更新日期：2013-04-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

journal_title：Journal of medical virology

authors： Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

更新日期：2002-05-01 00:00:00

abstract：:Seasonal fluctuations in hepatitis A have been observed in the Netherlands related to Turkish and Moroccan children after visiting their home countries. This study determined the prevalence and associated factors of hepatitis A virus (HAV) antibodies in Turkish and Moroccan children in Rotterdam. A random sample was t...

journal_title：Journal of medical virology

authors： Richardus JH,Vos D,Veldhuijzen IK,Groen J

更新日期：2004-02-01 00:00:00

abstract：:Infection with the human cytomegalovirus (HCMV) accelerates disease progression in human immunodeficiency virus 1 (HIV-1)-infected individuals. This has been attributed to the transaction of HIV-1 gene expression by HCMV gene products. For transactivation to be effective in vivo both viruses must be present in the sam...

journal_title：Journal of medical virology

authors： Bertram S,Hufert FT,van Lunzen J,von Laer D

更新日期：1996-08-01 00:00:00

abstract：:Guinea pigs infected with Argentine hemorrhagic fever virus (Junin) were treated with pooled, homologous convalescent sera. Use of 15,000 or 5,000 therapeutic units of immune sera prevented all signs of illness when administered within 24 hr of infection. We could also prevent illness and death in infected guinea pigs...

journal_title：Journal of medical virology

authors： Kenyon RH,Green DE,Eddy GA,Peters CJ

更新日期：1986-11-01 00:00:00

abstract：:Although hepatitis E virus (HEV) infection is a zoonosis, there is, currently, no standardized assay for quantitatively measuring anti-HEV antibody levels in HEV animal reservoirs. In this study, anti-HEV antibody positive serum from a rabbit (RS26) was calibrated by dose-response parallel line assay using the World H...

journal_title：Journal of medical virology

authors： Zhang Y,Wang L,Zeng H,Gong W,Wang L,Zhuang H

更新日期：2017-03-01 00:00:00

abstract：:Coronavirus-like particle(s) (CVLP) are faecal-derived pleomorphic membrane bound virus-like particles characterised by a fringe of club-shaped spikes that measure about 27 nm in length. The association of CVLP with a variety of social, clinical, and epidemiological factors was examined after a 69 month survey of faec...

journal_title：Journal of medical virology

authors： Marshall JA,Thompson WL,Gust ID

更新日期：1989-12-01 00:00:00

abstract：:Detection of respiratory viruses using polymerase chain reaction (PCR) is sensitive, specific and cost effective, having huge potential for patient management. In this study, the performance of an in-house developed conventional multiplex RT-PCR (mRT-PCR), real time RT-PCR (rtRT-PCR) and Luminex xTAG(®) RVP fast assay...

journal_title：Journal of medical virology

authors： Choudhary ML,Anand SP,Tikhe SA,Walimbe AM,Potdar VA,Chadha MS,Mishra AC

更新日期：2016-01-01 00:00:00

abstract：:Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...

journal_title：Journal of medical virology

authors： Portolani M,Cermelli C,Moroni A,Bertolani MF,Di Luca D,Cassai E,Sabbatini AM

更新日期：1993-02-01 00:00:00

abstract：:A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

journal_title：Journal of medical virology

authors： Baluchova K,Kirby M,Ahasan MM,Sweet C

更新日期：2008-07-01 00:00:00

abstract：:HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC ...

journal_title：Journal of medical virology

authors： Natarajan V,Kottilil S,Hazen A,Adelsberger J,Murphy AA,Polis MA,Kovacs JA

更新日期：2010-12-01 00:00:00

abstract：:We report a male caucasian German pediatric patient of no Arab or Mediterranean ancestry with virus associated CNS lesions in Griscelli's syndrome (GS; McKusick No. 214450). The boy presented with recurrent infections, and meningitis with subsequent progressive signs of increased intracranial pressure leading to death...

journal_title：Journal of medical virology

authors： Wagner M,Müller-Berghaus J,Schroeder R,Sollberg S,Luka J,Leyssens N,Schneider B,Krueger GR

更新日期：1997-11-01 00:00:00

abstract：:Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

journal_title：Journal of medical virology

authors： Murphy P,Nowak T,Lemon SM,Hilfenhaus J

更新日期：1993-09-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00

abstract：:To determine risk factors responsible for primary cytomegalovirus (CMV) infection in Taiwan, samples of blood for antibody to CMV were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti-CMV IgG antibody. Logistic regression analysis showed that seropositivity correlated with age, met...

journal_title：Journal of medical virology

authors： Shen CY,Chang WW,Chang SF,Chao MF,Huang ES,Wu CW

更新日期：1992-05-01 00:00:00

abstract：:Rotavirus was detected in the stools of five children stricken with sudden infant death syndrome (SIDS) over a three-week period. While none of the children had acute gastroenteritis, four of the five had acute upper respiratory infections. Rotavirus was also identified in tracheal aspirates from two of the infants. E...

journal_title：Journal of medical virology

authors： Yolken R,Murphy M

更新日期：1982-01-01 00:00:00

abstract：:The effect of protamine, atropine, selenocystamine, taxifolin, and catechin on the infectivity and antigenicity of the cell culture-adapted hepatitis A virus (HAV) strain CF 53 was studied. The toxicity on uninfected PLC/PRF/5 cells was examined for each antiviral compound by morphological and biochemical methods, in ...

journal_title：Journal of medical virology

authors： Biziagos E,Crance JM,Passagot J,Deloince R

更新日期：1987-05-01 00:00:00

abstract：:Epstein-Barr virus (EBV) genotypes can be distinguished based on gene sequence differences in EBV nuclear antigens 2, 3A, 3B, and 3C, and the BZLF1 promoter zone (Zp). EBV subtypes and BZLF1 Zp variants were examined in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated h...

journal_title：Journal of medical virology

authors： Imajoh M,Hashida Y,Murakami M,Maeda A,Sato T,Fujieda M,Wakiguchi H,Daibata M

更新日期：2012-06-01 00:00:00

abstract：:There are limited reports on the etiology of multiple enteric viruses causing acute gastroenteritis (AGE) in North India. In the present study we have determined the prevalence of three enteric viruses, namely rotavirus, astrovirus (AstV) and adenovirus (AdV) in a total of 312 diarrheic children (<5 years) hospitalize...

journal_title：Journal of medical virology

authors： Akdag AI,Gupta S,Khan N,Upadhayay A,Ray P

更新日期：2020-08-01 00:00:00

abstract：:Dengue, caused by any of the four types of Dengue virus (DENV) is the most important arbovirus in the world. In this study we performed a molecular surveillance of dengue during the greatest dengue outbreak that took place in Divinópolis, Minas Gerais state, Southeast Brazil, in 2013. Samples from 100 patients with cl...

journal_title：Journal of medical virology

authors： Dutra KR,Drumond BP,de Rezende IM,Nogueira ML,de Oliveira Lopes D,Calzavara Silva CE,Siqueira Ferreira JM,Dos Santos LL

更新日期：2017-06-01 00:00:00

abstract：:The quantification of human immunodeficiency virus type 1 (HIV-1) RNA or hepatitis C virus (HCV) RNA has been facilitated by adapting a spin column procedure for sample preparation and the use of chemiluminescent detection of polymerase chain reaction (PCR) products in microtiter plate format. All materials were comme...

journal_title：Journal of medical virology

authors： Lin HJ,Tanwandee T,Hollinger FB

更新日期：1997-01-01 00:00:00

abstract：:Previous studies demonstrated that in vitro infection with influenza A viruses altered several functions of human monocytes-macrophages but did not detectably alter functions of human lymphocytes. However, both types of cells were infected, as determined by production and surface expression of viral antigens. In the c...

journal_title：Journal of medical virology

authors： Roberts NJ Jr,Nichols JE

更新日期：1989-03-01 00:00:00

abstract：:Herpes simplex virus (HSV) establishes latency in neurons and recurrent infections in oral mucosa. This prospective study analyzes HSV prevalence in oral mucosal brush samples from men with known human papillomavirus (HPV) status. We hypothesized that HSV-1-infection could facilitate HPV persistence as a cofactor. Thi...

journal_title：Journal of medical virology

authors： Mäki J,Paavilainen H,Kero K,Hukkanen V,Syrjänen S

更新日期：2018-03-01 00:00:00

abstract：:Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To further understand inflammation in the airways following infection, we tested for the presence of matrix metalloproteinases (MMP) and natural tissue inhibitors ...

journal_title：Journal of medical virology

authors： Elliott MB,Welliver RC Sr,Laughlin TS,Pryharski KS,LaPierre NA,Chen T,Souza V,Terio NB,Hancock GE

更新日期：2007-04-01 00:00:00

abstract：:Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) have similar transmission routes, implying that patients infected with HIV are at particular risk for HBV infection. Patients who are co-infected with HIV and HBV progress more rapidly to end-stage liver disease and different HBV genotypes may have a disti...

journal_title：Journal of medical virology

authors： Pourkarim MR,Lemey P,Amini-Bavil-Olyaee S,Houspie L,Verbeeck J,Rahman M,Maes P,Vanwijngaerden E,Nevens F,Van Ranst M

更新日期：2011-11-01 00:00:00