Abstract:
:Coronavirus-like particle(s) (CVLP) are faecal-derived pleomorphic membrane bound virus-like particles characterised by a fringe of club-shaped spikes that measure about 27 nm in length. The association of CVLP with a variety of social, clinical, and epidemiological factors was examined after a 69 month survey of faeces received for routine testing at an infectious diseases hospital. CVLP was found most commonly in three groups: first, intellectually retarded individuals who were usually inmates of institutions; second, recent overseas travellers who were either Indochinese refugees/immigrants or were overseas travellers who had usually visited developing communities for lengthy periods; and, third, male homosexuals who had a history of multiple sexual contacts and/or venereal disease. It was concluded that the excretion of CVLP had a strong association with unhygienic living or working conditions irrespective of any clinical symptoms the individual might show.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Marshall JA,Thompson WL,Gust IDdoi
10.1002/jmv.1890290404subject
Has Abstractpub_date
1989-12-01 00:00:00pages
238-43issue
4eissn
0146-6615issn
1096-9071journal_volume
29pub_type
杂志文章abstract::The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 y...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890380110
更新日期:1992-09-01 00:00:00
abstract::Tumor necrosis factor receptor superfamily member 10 (TNFRSF10) is a death domain-containing receptor for the apoptotic ligand TNFSF10, which involves multiple processes, including hepatocarcinogenesis and immune response against HBV infection. Several single nucleotide polymorphisms (SNPs) were identified as expressi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24363
更新日期:2016-03-01 00:00:00
abstract::Strains of human coronavirus (HCV) isolated between 1974 and 1976 have been studied in vitro and in volunteers. All strains caused colds in volunteers, and those cultivable in tissue culture (TC) produced significantly more coryza and less sore throat than strains growing only in organ culture (OC). The TC strains wer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890130208
更新日期:1984-01-01 00:00:00
abstract::An "in-house" recombinant virus protease inhibitor susceptibility assay was carried out (median of 3 per patient) retrospectively in 26 patients failing HIV protease inhibitor based therapy at regular intervals to the initiation of the first protease inhibitor. Patients were treated with either indinavir (N = 6), rito...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10076
更新日期:2002-07-01 00:00:00
abstract::Enteroviruses (EVs) often infect humans, presenting as endemic or epidemic infections. In this study, the diversity of infecting EVs was studied among 146 children and 137 adults in a small community in Cameroon. The participants provided 2,458 fecal samples during 1-year monthly collection; 10 or more samples were ob...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23926
更新日期:2014-12-01 00:00:00
abstract::Norovirus is a major etiologic agent in worldwide outbreaks of gastroenteritis associated with food as well as person-to-person transmission. The ubiquitous nature of Norovirus necessitates simple and rapid detection methods with high accuracy and sensitivity. To this end, several investigators have evaluated the usef...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21626
更新日期:2009-12-01 00:00:00
abstract::Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26755
更新日期:2020-12-24 00:00:00
abstract::Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26245
更新日期:2020-06-30 00:00:00
abstract::Infection with the human papillomavirus (HPV) is responsible for 99.7% of cervical cancers, the second most prevalent neoplasia in women worldwide and the fifth leading cause of death by cancer in this population. In Chile, the incidence rate is 14.4 cases per 100,000 women per year and it is considered a significant ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22057
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26600
更新日期:2020-10-15 00:00:00
abstract::Three hepatitis B surface antigen (HBsAg) preparations were compared: purified intact 22-nm HBsAg particles; HBsAg-derived, sodium dodecyl sulfate (SDS)-denatured P25 + GP30 polypeptide pool; and nondenatured P25 + GP30 micelles. The micelles had the same polypeptide composition as the P25 + GP30 pool. The immunogenic...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890110205
更新日期:1983-01-01 00:00:00
abstract::Puumala hantavirus (PUUV) glycoproteins G1 and G2 and nucleocapsid protein (N) were expressed in BHK-21 cells by transfection of a plasmid producing a recombinant alphavirus replicon. Coexpression of G1 and G2 from separate constructs seemed to be important for the optimal folding of the glycoproteins, as evaluated by...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23847
更新日期:2014-06-01 00:00:00
abstract::As the coronavirus disease 2019 pandemic keep tackling global public health systems worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) genome keeps mutating. In that regard, the recent emergence of the B.1.1.7 lineage in the UK has called the attention of global authorities. One point of concer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26823
更新日期:2021-01-28 00:00:00
abstract:UNLABELLED:Viral respiratory tract infections in lung transplant recipients may be severe. During three consecutive winter-spring seasons, 49 symptomatic lung transplant recipients with suspected respiratory viral infection, and 26 asymptomatic patients were investigated for presence of respiratory viruses either in 56...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20555
更新日期:2006-03-01 00:00:00
abstract::As a consequence of the high prevalence of TorqueTeno virus (TTV) in blood donors, thalassemia patients frequently acquire various genotypes of this virus through therapeutic blood transfusions. At present, the clinical consequences of TTV infection remain indeterminate for these patients. Here, several hundred thalas...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21070
更新日期:2008-02-01 00:00:00
abstract::Polymorphisms upstream interleukin (IL)-28B gene and serum levels of interferon gamma inducible protein-10 (IP-10) are associated with spontaneous and treatment-induced hepatitis C virus (HCV) clearance. Patients with seronegative occult HCV infection are anti-HCV and serum HCV-RNA negative but have viral RNA in liver...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24322
更新日期:2016-02-01 00:00:00
abstract::Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890390211
更新日期:1993-02-01 00:00:00
abstract::Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890150112
更新日期:1985-01-01 00:00:00
abstract::The objective of this study was to investigate variation in human papillomavirus (HPV) type-16 load within histologically defined grades of cervical intraepithelial neoplasia. Two hundred and thirty-seven liquid based cytology samples were collected from women attending colposcopy clinics, DNA was extracted, and prese...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20875
更新日期:2007-09-01 00:00:00
abstract:PROBLEM:Objective studies that use validated questionnaires are needed to evaluate the changes in the sexual functions of women diagnosed with human papillomavirus (HPV) infection. METHOD OF STUDY:The study comprised 80 sexually active women diagnosed with a high-risk HPV infection. These patients were divided into fo...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25623
更新日期:2020-08-01 00:00:00
abstract::Hepatitis C virus core antigen (HCVcoreAg) may be measured in serum with a sensitive, recently validated assay. Beyond its value as a marker of viral infection, there are little data on its relation with clinical, histological, and virological parameters. In this study, the significance of HCVcoreAg levels was studied...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23672
更新日期:2013-11-01 00:00:00
abstract::A combined hepatitis A and B vaccine is available since 1996. Two separate open-label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17-43 years who received three doses of the vaccine following a 0, 1, and 6 m...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22264
更新日期:2012-01-01 00:00:00
abstract::From the Pacific Republic of Kiribati, 90/130 (69%) of hepatitis B-infected individuals carry antibodies to hepatitis delta virus. The prevalence of delta infection varied between geographically isolated subgroups in the population and delta antibodies were found more frequently in subjects over the age of 10. It is u...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890290210
更新日期:1989-10-01 00:00:00
abstract::The prevention of mother to child transmission of HIV-1 by zidovudine monotherapy is well known, but increasingly combination anti-retroviral therapy is prescribed during pregnancy. In this prospective study, 19 pregnant women with human immunodeficiency virus-1 (HIV-1) infection who elected to take anti-retroviral th...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199911)59:3<364::aid-jmv17
更新日期:1999-11-01 00:00:00
abstract::Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23936
更新日期:2014-12-01 00:00:00
abstract::Response to ribavirin therapy (1,000-1,200 mg/day for 6 months) was evaluated in nine patients with chronic hepatitis C virus (HCV) infections who had previously failed to respond to a 6-month course of alpha-interferon. All had chronic active hepatitis with elevated serum aminotransferase activities (mean +/- SD = 13...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章
doi:10.1002/jmv.1890450106
更新日期:1995-01-01 00:00:00
abstract::Little is known on the association between clinical factors and coronavirus disease 2019 (COVID-19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID-19 hospitalized patients to describe clinical, biological, and virological characteristics at hospital admission and over time, ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26601
更新日期:2020-10-15 00:00:00
abstract::Hepatitis B virus (HBV) e antigen (HBeAg) seroconversion during chronic HBV infection is known to play an important role in disease progression and patient response to antiviral agents. The aim of the present study was to analyze gender disparity in distribution of major hydrophilic region (MHR) variants according to ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21988
更新日期:2011-03-01 00:00:00
abstract::Alkali-dissociated, purified preparations of prototype coxsackievirus B4 release a protein kinase that catalyzes the incorporation of gamma-phosphate from 32P-labeled ATP into three virus capsid proteins (VP1, VP3, VP4), several additional proteins of the particle, and exogenous acceptor proteins. Using protamine sulf...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890190408
更新日期:1986-08-01 00:00:00