Comparative studies of the immunogenic activity of hepatitis B surface antigen (HBsAg) and HBsAg polypeptides.

abstract：:Enteroviruses (EVs) are RNA viruses that can cause many clinical syndromes including acute flaccid paralysis (AFP). Within the global polio laboratory network, EVs are categorized either as polioviruses or non-polio enteroviruses (NPEVs). Specific NPEVs have been described in polio-like residual paralytic events in AF...

journal_title：Journal of medical virology

authors： Tushabe P,Howard W,Bwogi J,Birungi M,Eliku JP,Kakooza P,Bukenya H,Namuwulya P,Gaizi J,Tibanagwa M,Kabaliisa T,Mulindwa J,Muhanguzi D,Suchard M,Gumede N,Bakamutumaho B

更新日期：2021-01-17 00:00:00

abstract：:A novel real-time PCR assay system was developed to quantify the cytomegalovirus (CMV) genome load. The real-time PCR assay could detect from 6 to over 10(6) copies of CMV-DNA with a wide linear range. The virus load of immunocompromised patients with symptomatic CMV infections was quantified and compared to that of a...

journal_title：Journal of medical virology

authors： Tanaka N,Kimura H,Iida K,Saito Y,Tsuge I,Yoshimi A,Matsuyama T,Morishima T

更新日期：2000-04-01 00:00:00

abstract：:Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...

journal_title：Journal of medical virology

authors： Portolani M,Cermelli C,Moroni A,Bertolani MF,Di Luca D,Cassai E,Sabbatini AM

更新日期：1993-02-01 00:00:00

abstract：:The human respiratory syncytial virus (HRSV) is the most important cause of admission to hospital for acute lower respiratory tract infections in infants and young children worldwide. Only few studies have investigated the molecular evolution of HRSV, and none has been conduct ed in Italy. The genetic diversity of the...

journal_title：Journal of medical virology

authors： Montieri S,Puzelli S,Ciccozzi M,Calzoletti L,Di Martino A,Milia MG,Rossi A,Piro F,Rezza G,Donatelli I

更新日期：2007-12-01 00:00:00

abstract：:Recent evidence suggested that neurological manifestations occur in patients with a severe form of coronavirus disease (COVID-19). On the basis of this issue, neurologists are very concerned about patients with neurological disorders, especially multiple sclerosis (MS), as consumers of immunosuppressive or immune-modu...

journal_title：Journal of medical virology

authors： Rostami Mansoor S,Ghasemi-Kasman M

更新日期：2020-10-12 00:00:00

abstract：:Analysis of 505 cases history of patients among men with viral hepatitis demonstrates that HBV infected patients represent 68.9% of the total and that a non-parenteral rate of transmission is the most likely means of hepatitis B infection. Saliva and serum testing for the presence of specific HBV markers (HBsAg, HBeAg...

journal_title：Journal of medical virology

authors： Zhevachevsky NG,Nomokonova NY,Beklemishev AB,Belov GF

更新日期：2000-08-01 00:00:00

abstract：:Seasonal fluctuations in hepatitis A have been observed in the Netherlands related to Turkish and Moroccan children after visiting their home countries. This study determined the prevalence and associated factors of hepatitis A virus (HAV) antibodies in Turkish and Moroccan children in Rotterdam. A random sample was t...

journal_title：Journal of medical virology

authors： Richardus JH,Vos D,Veldhuijzen IK,Groen J

更新日期：2004-02-01 00:00:00

abstract：:The presence of antibody to hepatitis A virus (anti-HAV) in 60% of procured owl monkeys (Aotus trivirgatus) held within the United States prompted a study of recently captured A trivirgatus in Panama. Only 2 of 145 newly captured monkeys, but all of 35 A trivirgatus held within a colony for over 100 days, were found t...

journal_title：Journal of medical virology

authors： Lemon SM,LeDuc JW,Binn LN,Escajadillo A,Ishak KG

更新日期：1982-01-01 00:00:00

abstract：:Interaction between herpesviruses and human immunodeficiency virus (HIV)1 is postulated in the progression of HIV disease. In order to evaluate the specific antibody responses directed to Epstein-Barr virus (EBV) and cytomegalovirus (CMV) and to provide serological evidence suggesting reactivation of these viruses abl...

journal_title：Journal of medical virology

authors： Quesnel A,Pozzetto B,Touraine F,Moja P,Lucht F,De The G,Touraine JL,Gaudin O,Genin C

更新日期：1992-01-01 00:00:00

abstract：:To establish gut immunity in monkeys to polio-virus type 1, we fed four juvenile bonnet monkeys (Macaca radiata) with 100 median infectious doses of the Mahoney strain of virus. The duration of viral shedding in the throat and faeces and the titre of virus in faeces were measured. Eighteen days after the last monkey s...

journal_title：Journal of medical virology

authors： Selvakumar R,John TJ

更新日期：1989-02-01 00:00:00

abstract：:The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...

journal_title：Journal of medical virology

authors： Cabana M,Clotet B,Martínez MA

更新日期：1999-12-01 00:00:00

abstract：:Strains of human coronavirus (HCV) isolated between 1974 and 1976 have been studied in vitro and in volunteers. All strains caused colds in volunteers, and those cultivable in tissue culture (TC) produced significantly more coryza and less sore throat than strains growing only in organ culture (OC). The TC strains wer...

journal_title：Journal of medical virology

authors： Reed SE

更新日期：1984-01-01 00:00:00

abstract：:The transmission of the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) can occur through airborne route, in addition to contaminated surfaces and objects. In hospitals, it has been confirmed by several studies that SRAS-CoV-2 can contaminate surfaces and medical equipment especially in hospitals dedicat...

journal_title：Journal of medical virology

authors： Elbadawy HM,Khattab A,Alalawi A,Aljohani F,Sundogji H,Mahmoud AS,Abouzied M,Eltahir HM,Alahmadey Z,Bahashwan S,Suliman BA

更新日期：2021-01-26 00:00:00

abstract：:A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells, herpesvirus nucle...

journal_title：Journal of medical virology

authors： Arao Y,Soushi S,Sato Y,Moriishi E,Ando Y,Yamada M,Padilla J,Uno F,Nii S,Kurata T

更新日期：1997-10-01 00:00:00

abstract：:Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

journal_title：Journal of medical virology

authors： Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

更新日期：2009-08-01 00:00:00

abstract：:Human parechoviruses (HPeVs) infection is associated with a wide range of clinical syndromes such as respiratory, gastrointestinal, neurologic diseases, and neonatal sepsis-like illness. The main objective of this study was to investigate the epidemiology of HPeVs infection in hospitalized patients in a period of 2 ye...

journal_title：Journal of medical virology

authors： Piralla A,Furione M,Rovida F,Marchi A,Stronati M,Gerna G,Baldanti F

更新日期：2012-04-01 00:00:00

abstract：:Chronic HCV infection has emerged as a complex multifaceted disease with manifestations extending beyond the liver. HCV plays a direct role in glucose metabolism leading to both insulin resistance and type 2 diabetes. To evaluate the changes in the glycemic state following Sofosbuvir-based treatment regimens in diabet...

journal_title：Journal of medical virology

authors： Abdel Alem S,Elsharkawy A,Fouad R,Adel E,Abdellatif Z,Musa S,Nagy A,Hussein MS,Yosry A,Esmat G

更新日期：2017-12-01 00:00:00

abstract：:Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...

journal_title：Journal of medical virology

authors： Kobayashi M,Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Suzuki F,Akuta N,Someya T,Matsuda M,Sato J,Takagi K,Miyakawa Y,Kumada H

更新日期：2002-12-01 00:00:00

abstract：:The long-term efficacy of lamivudine therapy in patients with hepatitis B virus (HBV) infection is still not clear. In this study, 20 non-cirrhotic Japanese patients infected with HBV received lamivudine therapy for more than 1 year and were followed for a median period of 8.5 years (range, 6.7-8.7 years). The rates o...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2005-04-01 00:00:00

abstract：:Previously, it was reported that productive viral infection, viral protein synthesis, and viral RNA replication of respiratory syncytial virus (RSV) operated efficiently in two human epithelial cell lines (HEp-2 and A549), but not in a human mast-cell line, HMC-1. Based on these observations, it was hypothesized that ...

journal_title：Journal of medical virology

authors： Shirato K,Ujike M,Kawase M,Matsuyama S

更新日期：2012-02-01 00:00:00

abstract：:Passively administered antibodies to conserved epitopes on the attachment (G) glycoprotein of human respiratory syncytial virus (hRSV) have potential in the immunoprophylaxis of human infections. This study set out to generate monoclonal antibodies (MAbs) recognizing all prevalent lineages of HRSV and capable of immun...

journal_title：Journal of medical virology

authors： Robinson MJ,Tan CS,Fenwick F,Chambers CJ,Routledge EG,Toms GL

更新日期：2014-07-01 00:00:00

abstract：:A hybrid cell line producing monoclonal antibodies recognizing an epitope encoded by the pre-(S)2 region of hepatitis B virus (HBV) genome was obtained by fusion of mouse myeloma cells with lymphocytes from mice immunized with HBV. The monoclonal antibody Mo-F124 secreted from the hybrid line reacted with the pre-S(2)...

journal_title：Journal of medical virology

authors： Budkowska A,Riottot MM,Dubreuil P,Lazizi Y,Brechot C,Sobczak E,Petit MA,Pillot J

更新日期：1986-10-01 00:00:00

abstract：:Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-inf...

journal_title：Journal of medical virology

authors： Smith DB,Paddy JO,Simmonds P

更新日期：2016-05-01 00:00:00

abstract：:The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remai...

journal_title：Journal of medical virology

authors： White L,García D,Boher Y,Blanco M,Pérez M,Romer H,Flores J,Pérez-Schael I

更新日期：1991-06-01 00:00:00

abstract：:GB virus C (GBV-C) is related to hepatitis C virus (HCV) and has a similar genomic structure. Some predictors for the efficacy of interferon (IFN) therapy on HCV have been reported: genotype, viral load, IFN dose, and the amino acid substitutions in the NS5A region, designated as the interferon sensitivity determining...

journal_title：Journal of medical virology

authors： Kato T,Mizokami M,Orito E,Ohba K,Nakano T,Kondo Y,Tanaka Y,Ueda R,Mukaide M,Yasuda K,Iino S

更新日期：1999-04-01 00:00:00

abstract：:Human parainfluenza viruses (HPIVs) are an important cause of acute lower respiratory tract infections (ALRTIs). HPIV-4, a newly identified virus, has been associated with severe ALRTIs recently. A total of 771 nasopharyngeal aspirate samples were collected from hospitalized children between March 2010 and February 20...

journal_title：Journal of medical virology

authors： Xiao NG,Duan ZJ,Xie ZP,Zhong LL,Zeng SZ,Huang H,Gao HC,Zhang B

更新日期：2016-12-01 00:00:00

abstract：:The immune response to guinea pig cytomegalovirus (gpCMV) was evaluated by immunoblotting. Preinoculation guinea pig plasma did not react with gpCMV antigen, whereas convalescent plasma reacted to at least 18 gpCMV-specific polypeptides. The initial immune response was primarily directed at polypeptides with MWs of 10...

journal_title：Journal of medical virology

authors： Kacica MA,Harrison CJ,Myers MG,Bernstein DI

更新日期：1990-11-01 00:00:00

abstract：:Group A rotaviruses are the main cause of acute gastroenteritis in children worldwide. The intermediate capsid protein VP6 encoded by segment 6 of the dsRNA genome is the major structural component of the virus and it is highly antigenic and immunogenic. VP6 is responsible for group and subgroup (SG) specificities, al...

journal_title：Journal of medical virology

authors： Tavares Tde M,de Brito WM,Fiaccadori FS,Parente JA,da Costa PS,Giugliano LG,Andreasi MS,Soares CM,Cardoso Dd

更新日期：2008-11-01 00:00:00

abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:The ability of the anti-cancer drug, 9-Nitrocamptothecin (9NC), to inhibit replication of HIV-1 in clinically relevant primary lymphocytic cells was studied. Primary peripheral blood lymphocytes (PBLs) from a non-infected donor were freshly infected with HIV-1 and treated with 9NC by using three different treatment sc...

journal_title：Journal of medical virology

authors： Hung CL,Doniger J,Palini A,Snyder SW,Radonovich MF,Brady JN,Pantazis P,Sadaie MR

更新日期：2001-07-01 00:00:00