Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo.

abstract：:Although analytical treatment interruption is used as a strategy to test immunotherapeutic agents in HIV-infection, it may pose a risk for study participants. The potential risks of short-term interruption of antiretroviral therapy (ART) during treatment with an autologous dendritic cell immune-based therapy (AGS-004-...

journal_title：Journal of medical virology

authors： Routy JP,Boulassel MR,Nicolette CA,Jacobson JM

更新日期：2012-06-01 00:00:00

abstract：:Stool specimens from 334 infants and young children hospitalized with diarrhea in the General Hospital, Kuala Lumpur, Malaysia between August and November, 1987 were analyzed for the presence of rotavirus double-stranded (ds) RNA by polyacrylamide gel electrophoresis. Of the 334 specimens analyzed, 32 (9.6%) were posi...

journal_title：Journal of medical virology

authors： Rasool NB,Hamzah M,Jegathesan M,Wong YH,Qian Y,Green KY

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children in low and middle-income countries. Human metapneumovirus (hMPV) is one of the most common viral etiological agents for ARIs in children. OBJECTIVES:In this study, we explored the genotypic diversity and the epidemio...

journal_title：Journal of medical virology

authors： Rahman MZ,Sumiya M,Sahabuddin M,Pell LG,Gubbay JB,Rahman R,Momtaz F,Azmuda N,Shanta SS,Jahan I,Rahman M,Mahmud AA,Roth DE,Morris SK

更新日期：2019-04-01 00:00:00

abstract：:Intramuscular (IM) influenza vaccines are about 50% effective in preventing clinical illness among the elderly and their effectiveness in eliciting mucosal response may be even lower. The aim of the present study was to evaluate the immunological effect of a novel inactivated intranasal (IN) trivalent whole influenza ...

journal_title：Journal of medical virology

authors： Muszkat M,Yehuda AB,Schein MH,Friedlander Y,Naveh P,Greenbaum E,Schlesinger M,Levy R,Zakay-Rones Z,Friedman G

更新日期：2000-05-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) 07_BC strain has caused serious outbreaks among injection drug users in Taiwan since 2004. The objective of this study was to conduct a molecular epidemiological study of HCV genotypes in intravenous drug users in Taiwan. Blood samples and ...

journal_title：Journal of medical virology

authors： Lee YM,Lin HJ,Chen YJ,Lee CM,Wang SF,Chang KY,Chen TL,Liu HF,Chen YM

更新日期：2010-01-01 00:00:00

abstract：:The importance of hepatitis B virus (HBV) genotypes for disease progression and response to interferon-alpha-based treatment is well established. While almost all patients in the Mediterranean area are infected with HBV genotype D, HBV genotype A is dominant in Northern Europe. However, the distribution of HBV genotyp...

journal_title：Journal of medical virology

authors： Deterding K,Constantinescu I,Nedelcu FD,Gervain J,Nemecek V,Srtunecky O,Vince A,Grgurevic I,Bielawski KP,Zalewska M,Bock T,Ambrozaitis A,Stanczak J,Takács M,Chulanov V,Slusarczyk J,Drazd'áková M,Wiegand J,Cornberg M,

更新日期：2008-10-01 00:00:00

abstract：:Knowledge of the current epidemiology of chronic liver disease in Italy is mostly obsolete and fragmentary for the lack of up-to-date consistent data. In 2001, a 6-month prevalence study was undertaken in 79 hospitals to assess the characteristics of chronic liver disease in Italy. Both prevalent and incident cases we...

journal_title：Journal of medical virology

authors： Sagnelli E,Stroffolini T,Mele A,Almasio P,Coppola N,Ferrigno L,Scolastico C,Onofrio M,Imparato M,Filippini P

更新日期：2005-04-01 00:00:00

abstract：:The complete VP1 protein of EV71 was truncated into six segments and fused to the C-terminal ends of full-length nucleocapsid protein (NPfl) and truncated NP (NPt; lacks 20% amino acid residues from its C-terminal end) of newcastle disease virus (NDV). Western blot analysis using anti-VP1 rabbit serum showed that the ...

journal_title：Journal of medical virology

authors： Sivasamugham LA,Cardosa MJ,Tan WS,Yusoff K

更新日期：2006-08-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks i...

journal_title：Journal of medical virology

authors： Feeney SA,Mitchell SJ,Mitchell F,Wyatt DE,Fairley D,McCaughey C,Coyle PV,O'Neill HJ

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIM:A meta-analysis was performed to identify COVID-19 patients presenting with gastrointestinal (GI) symptoms during the first and second pandemic waves and investigate their association with the disease outcomes. METHODS:A systematic search in PubMed, Scopus, Web of Science, ScienceDirect, and EMBASE ...

journal_title：Journal of medical virology

authors： Elshazli RM,Kline A,Elgaml A,Aboutaleb MH,Salim MM,Omar M,Munshi R,Mankowski N,Hussein MH,Attia AS,Toraih EA,Settin A,Killackey M,Fawzy MS,Kandil E

更新日期：2021-02-02 00:00:00

abstract：:Little is known on the association between clinical factors and coronavirus disease 2019 (COVID-19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID-19 hospitalized patients to describe clinical, biological, and virological characteristics at hospital admission and over time, ...

journal_title：Journal of medical virology

authors： Yazdanpanah Y,French COVID cohort investigators and study group.

更新日期：2020-10-15 00:00:00

abstract：:Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

journal_title：Journal of medical virology

authors： Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

更新日期：2017-08-01 00:00:00

abstract：:The reliability of the polymerase chain reaction (PCR) for prenatal diagnosis of human cytomegalovirus (HCMV) infection was determined by retrospective testing of 35 amniotic fluids identified previously as positive or negative for HCMV by virus isolation. Amniocentesis was performed in 26 pregnant women with primary ...

journal_title：Journal of medical virology

authors： Revello MG,Baldanti F,Furione M,Sarasini A,Percivalle E,Zavattoni M,Gerna G

更新日期：1995-12-01 00:00:00

abstract：:Corticosteroid use in transplant recipients increases the incidence and severity of Kaposi's sarcoma (KS), a disease associated with KS-associated herpesvirus (KSHV) infection. Recently, the prototypic corticosteroid, hydrocortisone, was shown to directly induce lytic cycle reactivation of KSHV in latently-infected BC...

journal_title：Journal of medical virology

authors： Zoeteweij JP,Rinderknecht AS,Davis DA,Yarchoan R,Blauvelt A

更新日期：2002-03-01 00:00:00

abstract：:Patterns of endemicity of human herpesvirus 8 (HHV8) are still undefined in some European populations, such as those from Western Balkan countries. Serum samples from 605 human immunodeficiency virus-seronegative subjects (299 Albanians and 306 Kosovars) were tested for the presence of HHV8 antibodies to a capsid-rela...

journal_title：Journal of medical virology

authors： Chironna M,Tosatti MA,Di Gangi IM,Sallustio A,Germinario C,Coluzzi M,Quarto M,Chieco-Bianchi L,Calabrò ML

更新日期：2006-07-01 00:00:00

abstract：:Sexually transmitted disease (STD) remains a major public health challenge in developed countries, exacerbated by the advent of the HIV epidemic. The objectives of this study were to assess the prevalence of serological markers of syphilis, HIV-1/2, HTLV-I/II, HBV, and HCV infections among immigrant sex workers in Mad...

journal_title：Journal of medical virology

authors： Gutiérrez M,Tajada P,Alvarez A,De Julián R,Baquero M,Soriano V,Holguín A

更新日期：2004-12-01 00:00:00

abstract：:The emergence of drug-resistant variants during antiretroviral therapy is a serious obstacle to sustained suppression of the human immunodeficiency virus type 1 (HIV-1). For that reason, resistance assays are essential to guide clinicians in the selection of optimal treatment regimens. Genotypic assays are less expens...

journal_title：Journal of medical virology

authors： Garcia-Perez J,Sanchez-Palomino S,Perez-Olmeda M,Fernandez B,Alcami J

更新日期：2007-02-01 00:00:00

abstract：:The immunogenicity of the Russian cold-adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60-ca, were compared in BALB/c mice with their respective wild-type parental viruses. Each ca donor strain was less immunogenic than its wild-type parent. The va...

journal_title：Journal of medical virology

authors： Wareing MD,Watson JM,Brooks MJ,Tannock GA

更新日期：2001-09-01 00:00:00

abstract：:Although many reports have already shown RSV outbreaks among hemato-oncology patients, genomic studies detecting similar RSV strains prior to an outbreak in the hospital are rare. In 2014, the University of the Ryukyus hospital hemato-oncology unit experienced, and successfully managed, a respiratory syncytial virus (...

journal_title：Journal of medical virology

authors： Nabeya D,Kinjo T,Parrott GL,Uehara A,Motooka D,Nakamura S,Nahar S,Nakachi S,Nakamatsu M,Maeshiro S,Haranaga S,Tateyama M,Tomoyose T,Masuzaki H,Horii T,Fujita J

更新日期：2017-08-01 00:00:00

abstract：:The purpose of this study was to investigate determinants of endemic hepatitis C virus (HCV) infection within communities in Taiwan. A two-phase study, including a seroprevalence survey and a prevalent case-control study at the first phase, which has been published previously, and a follow-up seroconversion determinat...

journal_title：Journal of medical virology

authors： Sun CA,Chen HC,Lu SN,Chen CJ,Lu CF,You SL,Lin SH

更新日期：2001-09-01 00:00:00

abstract：:Saliva and peripheral blood samples from 20 healthy adults were examined for the presence of human herpesvirus-6 (HHV-6) DNA sequences using the polymerase chain reaction. Eighteen out of 20 whole saliva samples contained detectable HHV-6 genomes. The majority of peripheral blood samples were also positive; however, t...

journal_title：Journal of medical virology

authors： Jarrett RF,Clark DA,Josephs SF,Onions DE

更新日期：1990-09-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00

abstract：:The Balkan Peninsula and Bulgaria in particular, is a well-known endemic region for Crimean-Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases of CCHF disease in humans. These ...

journal_title：Journal of medical virology

authors： Gergova I,Kunchev M,Kamarinchev B

更新日期：2012-04-01 00:00:00

abstract：:Epstein-Barr virus is present in the saliva of most persistently infected individuals and is generally thought to be spread by close oral contact. However, there are now several reports of EBV in genital secretions, suggesting the possibility of sexual transmission between adults. The present study was undertaken to i...

journal_title：Journal of medical virology

authors： Thomas R,Macsween KF,McAulay K,Clutterbuck D,Anderson R,Reid S,Higgins CD,Swerdlow AJ,Harrison N,Williams H,Crawford DH

更新日期：2006-09-01 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of hepatitis B e antigen (HBeAg) negative/treatment naïve subjects with low hepatitis B virus (HBV) DNA levels (<10(4)  copies/ml) and low alanine aminotransferase (ALT) levels (<2 × upper limit of normal) in patients with HBV-related hepatocellular carcinoma (HCC)....

journal_title：Journal of medical virology

authors： Zeng DW,Dong J,Zhang JM,Zhu YY,Jiang JJ,Liu YR

更新日期：2015-10-01 00:00:00

abstract：:Neurologic sequelae can be devastating complications of respiratory viral infections. We report the presence of virus in neural and capillary endothelial cells in frontal lobe tissue obtained at postmortem examination from a patient infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Our observ...

journal_title：Journal of medical virology

authors： Paniz-Mondolfi A,Bryce C,Grimes Z,Gordon RE,Reidy J,Lednicky J,Sordillo EM,Fowkes M

更新日期：2020-07-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：:A total of 402 fecal specimens collected during July 2003-June 2004 from infants and children with acute gastroenteritis, encompassing five localities (Maizuru, Tokyo, Sapporo, Saga, and Osaka) of Japan, were tested for the presence of norovirus by RT-PCR. It was found that 58 (14.4%) fecal specimens were positive for...

journal_title：Journal of medical virology

authors： Phan TG,Kuroiwa T,Kaneshi K,Ueda Y,Nakaya S,Nishimura S,Yamamoto A,Sugita K,Nishimura T,Yagyu F,Okitsu S,Müller WE,Maneekarn N,Ushijima H

更新日期：2006-07-01 00:00:00

abstract：:Taiwan was a hyperendemic area for hepatitis A and B viruses (HAV and HBV) infection before late 1980s. To study the seroprevalence of hepatitis A, B, C, and E viruses (HCV and HEV) infection among preschool children in Taiwan, a community-based survey was carried out in 54 kindergartens in 10 urban areas, 10 rural ar...

journal_title：Journal of medical virology

authors： Lin JB,Lin DB,Chen SC,Chen PS,Chen WK

更新日期：2006-01-01 00:00:00