Abstract:
:Patterns of endemicity of human herpesvirus 8 (HHV8) are still undefined in some European populations, such as those from Western Balkan countries. Serum samples from 605 human immunodeficiency virus-seronegative subjects (299 Albanians and 306 Kosovars) were tested for the presence of HHV8 antibodies to a capsid-related open reading frame (ORF65)-encoded protein and a latency-associated nuclear antigen (LANA) to determine HHV8 seroprevalence in populations from Albania and from the Kosovo region of former Yugoslavia. Levels of co- circulation with hepatitis A (HAV) and hepatitis B (HBV) viruses were also determined. HHV8 antibodies to at least one of the two antigens were detected in 28.8% of Albanians and 18% of Kosovars. The seroprevalence of HHV8 was found to be 25.0 and 16.8% in Albanian and Kosovar children ( journal_name journal_title authors doi subject pub_date pages issue eissn issn journal_volume pub_type
abstract::Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24950
更新日期:2018-02-01 00:00:00
abstract::Elevated telomerase activity is observed in about 90% of human cancers. This activity correlates strictly with human telomerase reverse transcriptase (hTERT). Previously, it was shown that the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induced telomerase activity in nasopharyngeal carcinoma cells. In ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20896
更新日期:2007-08-01 00:00:00
abstract::Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotides within the context of certain flanking bases (CpG motifs) have been shown to induce potent innate and adaptive immune responses. Vaginal delivery of CpG ODN alone protects mice from vaginal herpes simplex virus type-2 (HSV-2) challenge. He...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10518
更新日期:2003-12-01 00:00:00
abstract::The characteristics and response rate to pegylated interferon and ribavirin (PEG-INF + RBV) of patients with chronic hepatitis C infected with genotype 5 are poorly documented. A meta-analysis of two large phase III/IV prospective randomized clinical trials conducted in Belgium in patients with chronic hepatitis C (n ...
journal_title:Journal of medical virology
pub_type: 杂志文章,meta分析
doi:10.1002/jmv.22049
更新日期:2011-05-01 00:00:00
abstract::Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20073
更新日期:2004-06-01 00:00:00
abstract::A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890300407
更新日期:1990-04-01 00:00:00
abstract::To compare characteristics and outcomes of patients who had COVID-19 with Mycoplasma pneumoniae immunoglobulin M (IgM) antibodies to those without M. pneumoniae antibodies. We retrospectively reviewed cases admitted over a 4-week period between 17 March 2020 and 14 April 2020 to the Hoboken University Medical Center, ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26467
更新日期:2021-02-01 00:00:00
abstract::Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23884
更新日期:2014-09-01 00:00:00
abstract::Two major variables may cause false-negative results in prenatal diagnosis of congenital human cytomegalovirus (HCMV) infection: sensitivity of the techniques(s) used; and time elapsed between maternal infection and antenatal testing. Previous results indicated that rapid HCMV isolation from amniotic fluid samples and...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199809)56:1<99::aid-jmv16>
更新日期:1998-09-01 00:00:00
abstract::Polyomavirus infection occurring during childhood is followed by a lifelong latency in immunocompetent subjects. The major site of polyomavirus persistence are the uroepithelial cells which leads to oral transmission. It has recently been hypothesized that tonsils could be a possible reservoir. The role of tonsil, ade...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21786
更新日期:2010-07-01 00:00:00
abstract::In order to elucidate the pathogenesis of variant B human herpesvirus 6 (HHV-6) infection in skin tissues, an A431 cell line was inoculated with variant B HHV-6. HHV-6 causes abortive infection in the A431 cells, because neither late antigen (OHV-3 antigen) nor progeny virus is produced. Maximum levels of HHV-6 antige...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10461
更新日期:2003-09-01 00:00:00
abstract::Present diagnostic criteria for occult hepatitis B virus (HBV) infection requires blood or liver samples to test positive for at least two HBV DNA targets in hepatitis B surface antigen (HBsAg) negative individuals. These criteria were derived from studies involving referred or selected patient populations. The object...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23813
更新日期:2014-01-01 00:00:00
abstract::High risk types of human papillomaviruses E6/E7 oncogenes and their association with tumor suppressor genes products are the key factors of cervical carcinogenesis. This study proposed them as specific markers for cervical dysplasia screening. The aim of the study is to compare the clinical and prognostic significance...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24199
更新日期:2015-09-01 00:00:00
abstract::Dengue, caused by any of the four types of Dengue virus (DENV) is the most important arbovirus in the world. In this study we performed a molecular surveillance of dengue during the greatest dengue outbreak that took place in Divinópolis, Minas Gerais state, Southeast Brazil, in 2013. Samples from 100 patients with cl...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24729
更新日期:2017-06-01 00:00:00
abstract::Adenovirus infection during stem cell transplantation is associated with high morbidity and mortality. Adenovirus species B and C have been the main causes for these infections; however, epidemiological details about the species are still unclear. To clarify the contributions of species B and C adenovirus, the DNA was...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20796
更新日期:2007-03-01 00:00:00
abstract::In 2000, we monitored the course and persistence of human papillomavirus (HPV) infection in 54 women who were HPV positive and free of any cytological disease using HPV-DNA genotyping with a linear array assay (baseline). The impact of HPV infection on development of cervical cytological abnormality (dyskaryosis) was ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20062
更新日期:2004-05-01 00:00:00
abstract::Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B results from infection with hepatitis B virus mutants unable to produce HBeAg. It accounts for 7-30% of patients with chronic hepatitis B virus (HBV) worldwide, with the highest rates reported for Mediterranean Europe and Asia. Interferon (IFN) is currently th...
journal_title:Journal of medical virology
pub_type: 杂志文章,评审
doi:
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was found in the intestines and feces, but its clinical significance is not completely clear. We aim to characterize the longitudinal test results of SARS-CoV-2 RNA in anal swabs and to explore the association with disease severity. METHODS:We...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26307
更新日期:2021-02-01 00:00:00
abstract::The effect of interferon-gamma (IFN-gamma) on dengue virus multiplication in human peripheral blood monocytes was investigated. Enriched monocytes were treated with IFN-gamma and then infected with dengue virus type 2 either directly or in the presence of optimal infection-enhancing levels of antibodies. Pretreatment ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890450109
更新日期:1995-01-01 00:00:00
abstract::To define better the human immune response to individual structural proteins of human cytomegalovirus (HCMV), 55 human sera with different IgG and IgM titres were studied for their reactivity with HCMV structural polypeptides separated by SDS-PAGE and electrotransferred to nitrocellulose paper. The results obtained sh...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890170403
更新日期:1985-12-01 00:00:00
abstract::Chitin in the form of microparticles (chitin microparticles, CMP) has been demonstrated to be a potent stimulator of macrophages, promoting T-helper-1 (Th1) activation and cytokine response. In order to examine the mucosal adjuvant effect of CMP co-administered with influenza hemagglutinin (HA) vaccine against influen...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20247
更新日期:2005-01-01 00:00:00
abstract::We designed experiments to assess the effects of binding of the HSV-2 Fc receptor (FcR) to purified rabbit nonimmune IgG and purified Fc. Purified Fc (75 micrograms) or nonimmune IgG (100 micrograms) when bound to HSV-2 did not reduce infectivity but did protect the virions against thermal inactivation at 37 degrees C...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890130307
更新日期:1984-01-01 00:00:00
abstract::Enteroviruses (EVs) often infect humans, presenting as endemic or epidemic infections. In this study, the diversity of infecting EVs was studied among 146 children and 137 adults in a small community in Cameroon. The participants provided 2,458 fecal samples during 1-year monthly collection; 10 or more samples were ob...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23926
更新日期:2014-12-01 00:00:00
abstract::As with hepatitis B vaccines, the recently developed hepatitis A vaccine is suitable not only for individual protection, but also for public health control measures. For introduction into routine immunisation programmes, however, hepatitis A vaccine should preferably be combined with other already established vaccines...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章
doi:10.1002/jmv.1890440426
更新日期:1994-12-01 00:00:00
abstract::Epstein-Barr virus (EBV) serology continues to be the first diagnostic test when infectious mononucleosis is suspected. Due to possible mild immunosuppression in competitive athletes, EBV reactivation determined by increases in salivary viral load have been identified as one possible cause in recurrent respiratory inf...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23253
更新日期:2012-09-01 00:00:00
abstract::The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...
journal_title:Journal of medical virology
pub_type: 杂志文章,评审
doi:10.1002/jmv.25813
更新日期:2020-07-01 00:00:00
abstract::Using immunodiffusion, a major cross-reactivity had been previously demonstrated between hepatitis B(HBe/3 Ag) and the antigen reported in the serum on non A, non-B hepatitis patients, therefore redesignated NANBe Ag. By direct immunofluorescence a new antigen associated with, but distinct from, NANBe Ag has now been ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890080103
更新日期:1981-01-01 00:00:00
abstract::To establish gut immunity in monkeys to polio-virus type 1, we fed four juvenile bonnet monkeys (Macaca radiata) with 100 median infectious doses of the Mahoney strain of virus. The duration of viral shedding in the throat and faeces and the titre of virus in faeces were measured. Eighteen days after the last monkey s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890270208
更新日期:1989-02-01 00:00:00
abstract::Alfa-fetoprotein (AFP) is used as a marker of early hepatocarcinogenesis. However, the impact of hepatitis B virus surface antigen (HBsAg) on this relationship in patients with HBV infection is not clear. The present study evaluated the relation between HBsAg and AFP levels at the initial visit in 1,610 untreated HBV ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23790
更新日期:2014-01-01 00:00:00
abstract::The occurrence of viral coinfections in childhood pneumonia has received little attention, probably because suitable detection methods have been lacking. Between November 2004 and October 2006, the presence of 14 respiratory viruses in children aged less than 3 years old with community-acquired pneumonia were investig...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21271
更新日期:2008-10-01 00:00:00