Molecular and cellular determinants of cell-to-cell transmission of HCV in vitro.

abstract：:DNA samples from recurrent condylomata acuminata biopsies of Greek males and females were examined for the presence of human papillomavirus (HPV) DNA using high-stringency Southern blot hybridization analysis. Of the twenty-six biopsies, 25 were positive for the HPV 6/11-related DNA sequences, and when further analyze...

journal_title：Journal of medical virology

authors： Labropoulou V,Balamotis A,Tosca A,Rotola A,Mavromara-Nazos P

更新日期：1994-03-01 00:00:00

abstract：:Norovirus is one of the major causes of outbreaks and sporadic cases of acute gastroenteritis in young children worldwide. Obtaining local baseline information regarding this virus is important for developing and evaluating prevention strategies of norovirus transmission in children. The age, seasonal distribution and...

journal_title：Journal of medical virology

authors： Xu J,Yang Y,Sun J,Ding Y

更新日期：2009-10-01 00:00:00

abstract：:Pregnant women are not screened for HBsAg and anti-HCV antibodies in many African countries. As there are few data concerning the prevalence of HBV, HDV, and HCV serological markers in Benin, the aim of this study was to evaluate their 2011 prevalence in pregnant women undergoing HIV screening in a rural area of north...

journal_title：Journal of medical virology

authors： De Paschale M,Ceriani C,Cerulli T,Cagnin D,Cavallari S,Ndayaké J,Zaongo D,Priuli G,Viganò P,Clerici P

更新日期：2014-08-01 00:00:00

abstract：:Ideally, long-term lamivudine therapy should not induce tyrosine-methionine-aspartate-aspartate (YMDD) mutants (reverse transcription [rt]; rt M204I/V) in patients with chronic hepatitis B. There is little or no information on the clinical features of patients who do not develop such mutants. We analyzed 368 patients ...

journal_title：Journal of medical virology

authors： Hashimoto Y,Suzuki F,Hirakawa M,Kawamura Y,Yatsuji H,Sezaki H,Hosaka T,Akuta N,Kobayashi M,Saito S,Suzuki Y,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2010-04-01 00:00:00

abstract：:During the period 2007-2008 several epizootics of Yellow fever with dead of monkeys occurred in southeastern Brasil, Paraguay, and northeastern Argentina. In 2008 after a Yellow fever outbreak an exhaustive prevention campaign took place in Argentina using 17D live attenuated Yellow fever vaccine. This vaccine is cons...

journal_title：Journal of medical virology

authors： Pires-Marczeski FC,Martinez VP,Nemirovsky C,Padula PJ

更新日期：2011-12-01 00:00:00

abstract：:A molecular epidemiological study on common diarrheal viruses was conducted in Ho Chi Minh City, Vietnam between October 2002 and September 2003. Fecal samples were collected from 1,010 hospitalized children with acute gastroenteritis. Those samples were screened for groups A, B, and C rotavirus, adenovirus, genogroup...

journal_title：Journal of medical virology

authors： Nguyen TA,Yagyu F,Okame M,Phan TG,Trinh QD,Yan H,Hoang KT,Cao AT,Le Hoang P,Okitsu S,Ushijima H

更新日期：2007-05-01 00:00:00

abstract：:Human herpesvirus 6 (HHV6) is a beta-herpesvirus capable of infecting several cell types from different origins. HHV6 is the etiological agent of exantem subitum and has been associated with several diseases, all characterized by an inflammatory response triggered by chemokines. We show that strain U1102 of HHV6 is ab...

journal_title：Journal of medical virology

authors： Caruso A,Favilli F,Rotola A,Comar M,Horejsh D,Alessandri G,Grassi M,Di Luca D,Fiorentini S

更新日期：2003-07-01 00:00:00

abstract：:The effects of 6-diazo-5-oxo-L-norleucine (DON), 2-deoxy-D-glucose (DOG), and tunicamycin (TM) on the replication of poliovirus (PV) and vesicular stomatitis virus (VSV) were examined. During a 48-hr replication period, TM, DON, and DOG inhibit VSV plaque formation in HEp-2 cells by 99.9%, 99.8%, and 99.9% respectivel...

journal_title：Journal of medical virology

authors： Goldstein G,Guskey LE

更新日期：1984-01-01 00:00:00

abstract：:HIV is among the most generically variable of human pathogens. A comprehensive and detailed description of HIV strains in the pandemic is an important foundation for diagnosis, treatment, and prevention. The current sequence database for HIV includes almost 800 complete genome sequences, documenting HIV-1 groups M, O,...

journal_title：Journal of medical virology

authors： McCutchan FE

更新日期：2006-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is an important risk factor for atherosclerosis (AS). Numerous studies have been conducted to analyze the association between HCMV infection and risk of AS, but no clear consensus has been reached. So the objective of this paper was aimed to demonstrate the relationship between H...

journal_title：Journal of medical virology

authors： Jia YJ,Liu J,Han FF,Wan ZR,Gong LL,Liu H,Zhang W,Wardell T,Lv YL,Liu LH

更新日期：2017-12-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:Most cases of hepatocellular carcinoma (HCC) are due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection worldwide. The aim of this study was to determine the viral genotypes and frequency of 17 mutations (15 for HBV and 2 for HCV), described previously as able to influence the course of chronic li...

journal_title：Journal of medical virology

authors： Araujo OC,Barros JJ,do Ó KM,Nabuco LC,Luz CA,Perez RM,Niel C,Villela-Nogueira CA,Araujo NM

更新日期：2014-02-01 00:00:00

abstract：:The objective of the study was to assess the genotypic and phenotypic properties of 18 viral strains from human immunodeficiency virus-1 (HIV-1) positive patients and to identify subtype C isolates for vaccine design strategies. All the isolates were non-syncytium-inducing (NSI) in both the primary and MT-2 cell cultu...

journal_title：Journal of medical virology

authors： Treurnicht FK,Smith TL,Engelbrecht S,Claassen M,Robson BA,Zeier M,van Rensburg EJ

更新日期：2002-10-01 00:00:00

abstract：:Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

journal_title：Journal of medical virology

authors： Brufsky A

更新日期：2020-07-01 00:00:00

abstract：:The severe acute respiratory syndrome (SARS) leads to severe injury in the lungs with multiple factors, though the pathogenesis is still largely unclear. This paper describes the particular analyses of the transcriptome of human lung tissue that was infected by SARS-associated coronavirus (SARS-CoV). Random primers we...

journal_title：Journal of medical virology

authors： Wu H,Wang J,Deng R,Xing K,Xiong Y,Huang J,He X,Wang X

更新日期：2011-04-01 00:00:00

abstract：:Fifty-six renal allograft recipients were studied prospectively for 3 months or longer after transplant. The polymerase chain reaction (PCR) was used to screen peripheral blood leucocyte (PBL) specimens for CMV, human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7) DNA (DNAemia) in 67 healthy controls and in seria...

journal_title：Journal of medical virology

authors： Osman HK,Peiris JS,Taylor CE,Warwicker P,Jarrett RF,Madeley CR

更新日期：1996-04-01 00:00:00

abstract：:As with hepatitis B vaccines, the recently developed hepatitis A vaccine is suitable not only for individual protection, but also for public health control measures. For introduction into routine immunisation programmes, however, hepatitis A vaccine should preferably be combined with other already established vaccines...

journal_title：Journal of medical virology

authors： Ambrosch F,Wiedermann G,André FE,Delem A,Gregor H,Hofmann H,D'Hondt E,Kundi M,Wynen J,Kunz C

更新日期：1994-12-01 00:00:00

abstract：:Individual specific antigenic rubella virus (RV) structural proteins are required for accurate serological diagnosis of acute and congenital rubella infections as well as rubella immune status. The RV envelope glycoprotein E1 is the major target antigen and plays an important role in viral-specific immune responses. T...

journal_title：Journal of medical virology

authors： Seto NO,Gillam S

更新日期：1994-10-01 00:00:00

abstract：:There is little information on JC virus (JCV) infection in renal transplant patients. A long-term prospective follow-up study was conducted to assess the incidence of JCV DNA in the blood of 103 adult renal transplant patients enrolled prospectively between 1 January and 31 December 2006. Patients were monitored until...

journal_title：Journal of medical virology

authors： Mengelle C,Kamar N,Mansuy JM,Sandres-Sauné K,Legrand-Abravanel F,Miédougé M,Rostaing L,Izopet J

更新日期：2011-01-01 00:00:00

abstract：:The prevalence rate of IgG antibodies to cytomegalovirus (CMV) was determined in a sample of 567 women of childbearing age in the southern part of Israel by the immunoperoxidase assay to membrane antigen (IPAMA) technique. Urban Jewish women of Afro-Asian origin showed significantly higher rates of seropositivity than...

journal_title：Journal of medical virology

authors： Urkin J,Sarov B,Naggan L,Haikin H,Sarov I

更新日期：1988-01-01 00:00:00

abstract：:Response to ribavirin therapy (1,000-1,200 mg/day for 6 months) was evaluated in nine patients with chronic hepatitis C virus (HCV) infections who had previously failed to respond to a 6-month course of alpha-interferon. All had chronic active hepatitis with elevated serum aminotransferase activities (mean +/- SD = 13...

journal_title：Journal of medical virology

authors： Koskinas J,Tibbs C,Saleh MG,Pereira LM,McFarlane IG,Williams R

更新日期：1995-01-01 00:00:00

abstract：:Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-inf...

journal_title：Journal of medical virology

authors： Smith DB,Paddy JO,Simmonds P

更新日期：2016-05-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this stud...

journal_title：Journal of medical virology

authors： Greco L,Uceda Renteria SC,Guarneri D,Orlandi A,Zoccoli A,Benardon S,Cusini M,Lunghi G

更新日期：2018-08-01 00:00:00

abstract：:A sensitive microtitre radioimmunoassay was developed for detection of IgM antibodies to delta antigen. The assay was based on the selective binding of IgM from test sera to antihuman IgM (u-chain specific) fixed to wells of a microtitre plate, and utilized delta antigen extracted from the liver of an experimentally i...

journal_title：Journal of medical virology

authors： Dimitrakakis M,Waters MJ,Wootton A,Gust I

更新日期：1986-12-01 00:00:00

abstract：:The immune response to guinea pig cytomegalovirus (gpCMV) was evaluated by immunoblotting. Preinoculation guinea pig plasma did not react with gpCMV antigen, whereas convalescent plasma reacted to at least 18 gpCMV-specific polypeptides. The initial immune response was primarily directed at polypeptides with MWs of 10...

journal_title：Journal of medical virology

authors： Kacica MA,Harrison CJ,Myers MG,Bernstein DI

更新日期：1990-11-01 00:00:00

abstract：:During the 1976 Ebola virus outbreak in Sudan, the investigations team gained the impression that fewer haemorrhagic manifestations and few fatalities occurred during the later stages of the epidemic after the virus had undergone several generations in man. This impression was also noted in guinea pigs experimentally ...

journal_title：Journal of medical virology

authors： Bowen ET,Platt GS,Lloyd G,Raymond RT,Simpson DI

更新日期：1980-01-01 00:00:00

abstract：:Only recently have we begun to fully realize the diversity of virions within a single human isolate of the group B Coxsackieviruses. These intratypic (strain) differences may be one of the important factors influencing pathogenesis, e.g., myocarditis vs. pancreatitis. Yet, until the virion strains within a type can be...

journal_title：Journal of medical virology

authors： Webb SR,Kearse KP,Foulke CL,Hartig PC,Prabhakar BS

更新日期：1986-09-01 00:00:00

abstract：:We have tested a multiplex polymerase chain reaction (PCR) human papillomavirus (HPV) genotyping assay to fill the need for rapid and low-cost HPV detection in Sub-Saharan Africa. This method allows high throughput genotyping and simultaneous detection of 14 high-risk and two low-risk HPV types, by PCR amplification o...

journal_title：Journal of medical virology

authors： Samwel K,Kahesa C,Mwaiselage J,Gonzalez D,West JT,Wood C,Palefsky J,Angeletti PC

更新日期：2019-02-01 00:00:00

abstract：:The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

journal_title：Journal of medical virology

authors： Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

更新日期：2020-07-25 00:00:00

abstract：:The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...

journal_title：Journal of medical virology

authors： Arora NK,Nanda SK,Gulati S,Ansari IH,Chawla MK,Gupta SD,Panda SK

更新日期：1996-03-01 00:00:00