Human papillomavirus infection among women with cytological abnormalities in Switzerland investigated by an automated linear array genotyping test.

Abstract:

:Limited data are available describing human papillomavirus (HPV) genotype distribution among females with cytological abnormalities in Switzerland. Cervical cell specimens obtained from 5,318 women were screened routinely by liquid-based Pap smear. All specimens with cellular abnormalities were analyzed subsequently for HPV DNA by the Linear Array HPV genotyping test. Cellular abnormalities were found in 202 (3.8%) specimens, of which 150 (74.3%) were positive for high-risk (HR) HPV. HR-HPV was detected in 20 (60.6%; 95% CI, 43.7-75.4%) of 33 specimens with atypical squamous cells of undetermined significance compared to 98 (72.1%; 95% CI, 64-78.9%) of 136 low-grade squamous intraepithelial lesions and 32 (97%; 95% CI, 83.4-99.9%) of 33 high-grade squamous intraepithelial lesions. The cumulative prevalence of HR-HPV other than HPV 16 and 18 was significantly higher than HPV 16 and/or 18 lesions with atypical squamous cells and low-grade lesions and was comparable in high-grade squamous intraepithelial lesions. The most common HR-HPV genotypes were HPV 16 (15.2%), HPV 31 (12.1%), HPV 58 (12.1%), HPV 51 (9.1%), and HPV 59 (9.1%) in women with atypical squamous cells, HPV 16 (25%), HPV 51 (16.9%), HPV 52 (11.8%), HPV 31 (9.6%), and HPV 56 (8.1%) in women with low-grade lesions (LSIL) and HPV 16 (57.6%), HPV 18 (18.2%), HPV 31 (15.2%), HPV 52 (12.1%), and HPV 58 (6.1%) in women with high-grade lesions (HSIL).

journal_name

J Med Virol

authors

Dobec M,Bannwart F,Kilgus S,Kaeppeli F,Cassinotti P

doi

10.1002/jmv.22126

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

1370-6

issue

8

eissn

0146-6615

issn

1096-9071

journal_volume

83

pub_type

杂志文章
  • Upregulation of Epstein-Barr virus-encoded latent membrane protein by human herpesvirus 6 superinfection of EBV-carrying Burkitt lymphoma cells.

    abstract::The effect of HHV-6 strain A infection on the expression of Epstein-Barr virus- (EBV-) encoded growth transformation-associated genes in two EBV-positive Burkitt lymphoma cell lines, Akata and P3HR-3, was investigated. The results indicate that HHV-6A upregulates the expression of the latent membrane protein LMP-1 in ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Cuomo L,Trivedi P,de Grazia U,Calogero A,D'Onofrio M,Yang W,Frati L,Faggioni A,Rymo L,Ragona G

    更新日期:1998-07-01 00:00:00

  • Specific IgG and IgA antibodies to herpes simplex virus (HSV)-induced surface antigen in patients with HSV infections and in healthy adults.

    abstract::Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890140303

    authors: Hadar T,Sarov I

    更新日期:1984-01-01 00:00:00

  • Neutralization epitope diversity of coxsackievirus B4 isolates detected by monoclonal antibodies.

    abstract::Only recently have we begun to fully realize the diversity of virions within a single human isolate of the group B Coxsackieviruses. These intratypic (strain) differences may be one of the important factors influencing pathogenesis, e.g., myocarditis vs. pancreatitis. Yet, until the virion strains within a type can be...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890200103

    authors: Webb SR,Kearse KP,Foulke CL,Hartig PC,Prabhakar BS

    更新日期:1986-09-01 00:00:00

  • Molecular epidemiology of human bocavirus infection in hospitalized children with acute gastroenteritis in South Africa, 2009-2015.

    abstract::Human bocavirus (HBoV) is known to be associated with a variety of clinical manifestation including acute gastroenteritis (AGE). Despite their global prevalence, no data is available on the epidemiology of HBoV associated with AGE in South Africa (SA). Between April 2009 and April 2015, 3765 stool specimens were colle...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25634

    authors: Netshikweta R,Chidamba L,Nadan S,Taylor MB,Page NA

    更新日期:2020-08-01 00:00:00

  • Real-time polymerase chain reaction for diagnosing infectious mononucleosis in pediatric patients: A systematic review and meta-analysis.

    abstract::In this meta-analysis, we evaluated the diagnostic role of Epstein-Barr virus deoxyribonucleic acid detection and quantitation in the serum of pediatric and young adult patients with infectious mononucleosis. The primary outcome of this meta-analysis was the sensitivity and specificity of Epstein-Barr virus (EBV) deox...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/jmv.24402

    authors: Jiang SY,Yang JW,Shao JB,Liao XL,Lu ZH,Jiang H

    更新日期:2016-05-01 00:00:00

  • HIV-1 variability and progression to AIDS: a longitudinal study.

    abstract::HIV-1 replicative activity and its relation to the clinical and immunological evolution of infection was studied in a group of 150 HIV-1 seropositive Italian i.v. drug abusers over a 1 year period. HIV-1 was isolated from 90 (60%) subjects; two groups of isolates were distinguished, according to replicative activity "...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890320411

    authors: Fiore JR,Calabró ML,Angarano G,De Rossi A,Fico C,Pastore G,Bianchi LC

    更新日期:1990-12-01 00:00:00

  • Molecular epidemiology of norovirus infection among children with acute gastroenteritis in Shanghai, China, 2001-2005.

    abstract::Norovirus is one of the major causes of outbreaks and sporadic cases of acute gastroenteritis in young children worldwide. Obtaining local baseline information regarding this virus is important for developing and evaluating prevention strategies of norovirus transmission in children. The age, seasonal distribution and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21569

    authors: Xu J,Yang Y,Sun J,Ding Y

    更新日期:2009-10-01 00:00:00

  • Identification of human astrovirus infections among children with acute gastroenteritis in the Southern Part of Vietnam during 2005-2006.

    abstract::A molecular epidemiological study on common diarrheal viruses was conducted in a children's hospital in Ho Chi Minh City between December 2005 and November 2006. Fecal samples were collected from 502 pediatric patients with acute gastroenteritis, and were screened for eight types of viral agents. Human astroviruses (H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21032

    authors: Nguyen TA,Hoang L,Pham le D,Hoang KT,Mizuguchi M,Okitsu S,Ushijima H

    更新日期:2008-02-01 00:00:00

  • Favorable efficacy of glecaprevir plus pibrentasvir as salvage therapy for HCV failures to prior direct-acting antivirals regimens.

    abstract::In real-world settings, not much information is probably available on the treatment efficacy of the combination of glecaprevir and pibrentasvir (G/P) as a salvage therapy in failures of prior direct-acting antiviral (DAA) regimens. Especially, the evolution of NS5A resistance-associated variants (RAVs) and treatment e...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25278

    authors: Akuta N,Sezaki H,Suzuki F,Fujiyama S,Kawamura Y,Hosaka T,Kobayashi M,Kobayashi M,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kumada H

    更新日期:2019-01-01 00:00:00

  • Development of a hepatitis delta virus antibody assay for study of the prevalence of HDV among individuals infected with hepatitis B virus in China.

    abstract::Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23212

    authors: Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

    更新日期:2012-03-01 00:00:00

  • Polymorphism of the capsid L1 gene of human papillomavirus types 31, 33, and 35.

    abstract::The L1 gene encodes for the major capsid protein of human papillomaviruses (HPV). There is limited information on the polymorphism of L1 for types related to HPV-16. This report explores the polymorphism of L1 in phylogenetically related types 31, 33, and 35 compared to HPV-16. Genital specimens collected from 732 HIV...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21777

    authors: Cornut G,Gagnon S,Hankins C,Money D,Pourreaux K,Franco EL,Coutlée F,Canadian Women's HIV Study Group.

    更新日期:2010-07-01 00:00:00

  • Cell cycle perturbation in the hepatocytes of HCV core transgenic mice following common bile duct ligation is associated with enhanced p21 expression.

    abstract::Hepatitis C virus (HCV) core protein has been reported to alter the cell cycle in vitro, but the data remain inconclusive, and in vitro experiments do not represent precisely events that occur in vivo, which may involve hepatic inflammation or regeneration. A group of double-transgenic mice carrying tetracycline trans...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21403

    authors: Chang ML,Chen TH,Chang MY,Yeh CT

    更新日期:2009-03-01 00:00:00

  • Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: an age- and sex-matched case-control study.

    abstract::It was reported previously food-borne transmission of hepatitis E virus (HEV) to humans from deer meat. The present study attempted to clarify whether eating uncooked deer meat is a major epidemiological risk factor for HEV infection in Kasai, a city in western Japan. In total, 45 volunteer subjects with experience of...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20147

    authors: Tei S,Kitajima N,Ohara S,Inoue Y,Miki M,Yamatani T,Yamabe H,Mishiro S,Kinoshita Y

    更新日期:2004-09-01 00:00:00

  • Hepatitis A antibodies in attenders of London Travel Clinics: cost-benefit of screening prior to hepatitis A immunisation.

    abstract::The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890440414

    authors: Zuckerman JN,Powell L

    更新日期:1994-12-01 00:00:00

  • The detection of SRAS-CoV-2 in outpatient clinics and public facilities during the COVID19 pandemic.

    abstract::The transmission of the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) can occur through airborne route, in addition to contaminated surfaces and objects. In hospitals, it has been confirmed by several studies that SRAS-CoV-2 can contaminate surfaces and medical equipment especially in hospitals dedicat...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26819

    authors: Elbadawy HM,Khattab A,Alalawi A,Aljohani F,Sundogji H,Mahmoud AS,Abouzied M,Eltahir HM,Alahmadey Z,Bahashwan S,Suliman BA

    更新日期:2021-01-26 00:00:00

  • Analytical performance of a low-cost multiplex polymerase chain reaction human papillomavirus genotyping assay for use in Sub-Saharan Africa.

    abstract::We have tested a multiplex polymerase chain reaction (PCR) human papillomavirus (HPV) genotyping assay to fill the need for rapid and low-cost HPV detection in Sub-Saharan Africa. This method allows high throughput genotyping and simultaneous detection of 14 high-risk and two low-risk HPV types, by PCR amplification o...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25329

    authors: Samwel K,Kahesa C,Mwaiselage J,Gonzalez D,West JT,Wood C,Palefsky J,Angeletti PC

    更新日期:2019-02-01 00:00:00

  • Molecular analysis of enterovirus in Cameroon by partial 5'UTR-VP4 gene sequencing reveals a high genetic diversity and frequency of infections.

    abstract::Enteroviruses (EVs) often infect humans, presenting as endemic or epidemic infections. In this study, the diversity of infecting EVs was studied among 146 children and 137 adults in a small community in Cameroon. The participants provided 2,458 fecal samples during 1-year monthly collection; 10 or more samples were ob...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23926

    authors: Ayukekbong JA,Fobisong C,Lindh M,Nkuo-Akenji T,Bergström T,Norder H

    更新日期:2014-12-01 00:00:00

  • First case of focal epilepsy associated with SARS-coronavirus-2.

    abstract::A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either no...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26113

    authors: Elgamasy S,Kamel MG,Ghozy S,Khalil A,Morra ME,Islam SMS

    更新日期:2020-10-01 00:00:00

  • A novel real-time PCR system for simultaneous detection of human viruses in clinical samples from patients with uncertain diagnoses.

    abstract::A novel simultaneous detection system for human viruses was developed using a real-time polymerase chain reaction (PCR) system to identify causes of infection in clinical samples from patients with uncertain diagnoses. This system, designated as the "multivirus real-time PCR," has the potential to detect 163 human vir...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21962

    authors: Katano H,Kano M,Nakamura T,Kanno T,Asanuma H,Sata T

    更新日期:2011-02-01 00:00:00

  • Prevalence and quantitation of adenovirus DNA from human tonsil and adenoid tissues.

    abstract::In this study, real-time PCR was used to quantify adenovirus DNA in cell suspensions prepared from 106 right and left tonsils and 10 adenoids obtained from 57 patients who underwent routine tonsillectomies and/or adenoidectomies. Eighty-four (72.4%) tonsils and adenoids samples were positive for HAdV by real-time PCR....

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23678

    authors: Alkhalaf MA,Guiver M,Cooper RJ

    更新日期:2013-11-01 00:00:00

  • Elevated histone H3 citrullination is associated with increased Beclin1 expression in HBV-related hepatocellular carcinoma.

    abstract::Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25663

    authors: Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

    更新日期:2020-08-01 00:00:00

  • Treatment of varicella in the immunocompetent adult.

    abstract::Varicella in the immunocompetent adult is an infrequent but potentially serious infection. Previous studies in immunocompetent hosts and normal adults have demonstrated the value of intravenous acyclovir in the treatment of varicella-zoster virus infections. Oral acyclovir has also shown efficacy in both normal adults...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.1890410517

    authors: Wallace MR,Bowler WA,Oldfield EC 3rd

    更新日期:1993-01-01 00:00:00

  • Recent trends in hepatitis A incidence in Brazil.

    abstract::Hepatitis A incidence has been decreasing in Brazil since child vaccination was implemented in 2014. This trend was interrupted by an outbreak among adult male in São Paulo in 2017. This study was outlined to estimate whether the increase of hepatitis A cases among adult men in Brazil was restricted to São Paulo. Case...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25694

    authors: De Oliveira TM,Vieira NSG,Sepp TDS,Souto FJD

    更新日期:2020-08-01 00:00:00

  • The role of autophagy in human cytomegalovirus IE2 expression.

    abstract::The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26357

    authors: Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

    更新日期:2020-07-25 00:00:00

  • Methylation of Epstein-Barr virus Rta promoter in EBV primary infection, reactivation and lymphoproliferation.

    abstract::During Epstein-Barr virus (EBV) latency, the EBV genome is largely silenced by methylation. This silencing is overturned during the switch to the lytic cycle. A key event is the production of the viral protein Zta which binds to three Zta-response elements (ZRE) from the Rta promoter (Rp), two of which (ZRE2 and ZRE3)...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24524

    authors: Germi R,Guigue N,Lupo J,Semenova T,Grossi L,Vermeulen O,Epaulard O,de Fraipont F,Morand P

    更新日期:2016-10-01 00:00:00

  • Virus-induced autoimmunity in hepatitis C virus infections: a rare event.

    abstract::Serial serum samples from 16 Italian patients presenting with acute hepatitis C virus (HCV) infections (which progressed to chronic hepatitis in six) were screened for the non-organ-specific autoantibodies most frequently associated with autoimmune hepatitis (AIH), as well as for antibodies against the hepatic asialog...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890420113

    authors: McFarlane BM,Bridger C,Tibbs CJ,Saleh MG,Fuzio A,Verucchi G,Attard L,Boschi A,Chiodo F,McFarlane IG

    更新日期:1994-01-01 00:00:00

  • Analysis of strain variation of R1 repeated structure in varicella-zoster virus DNA by polymerase chain reaction.

    abstract::The tandem direct reiteration R1 in the varicella-zoster virus genome consists of two elements: units composed of 18 bp and those having 15 bp, both of whose numbers and types of combination patterns vary among strains. The variations of the R1 structure were examined in order to differentiate between the wild strains...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Yoshida M,Tamura T,Hiruma M

    更新日期:1999-05-01 00:00:00

  • Diagnosis of enterovirus 70 infection by demonstration of IgM antibodies.

    abstract::Since outbreaks of severe acute hemorrhagic conjunctivitis occur worldwide [Hierholzer and Hatch, 1985] and the majority of the epidemics are caused by enterovirus 70 (EV-70), we developed an EV-70 IgM ELISA to simplify the diagnosis of these outbreaks. The test is based on the capture antibody technique and the use o...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890210404

    authors: Wulff H,Anderson LJ,Pallansch MA,de Souza Carvalho RP

    更新日期:1987-04-01 00:00:00

  • Fulminant demyelinating encephalomyelitis associated with productive HHV-6 infection in an immunocompetent adult.

    abstract::Human herpesvirus 6 (HHV-6), the etiologic agent of roseola in young children, has been reported to be detectable in the brain of many neurologically normal adults, although regional localization to plaques of multiple sclerosis has also been demonstrated. Large amounts of this virus were present in multifocal demyeli...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199707)52:3<301::aid-jmv11

    authors: Novoa LJ,Nagra RM,Nakawatase T,Edwards-Lee T,Tourtellotte WW,Cornford ME

    更新日期:1997-07-01 00:00:00

  • Prevalence and risk factors of hepatitis C and B virus infections in hemodialysis patients and their spouses: a multicenter study in Beijing, China.

    abstract::Hemodialysis patients are at risk for hepatitis C and B virus infections. This study investigated the prevalences and risk factors of HCV and HBV infection and the distribution of HCV genotypes among hemodialysis patients and their spouses. From August to November 2011, a cross-sectional study was conducted on 20 hemo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jmv.23486

    authors: Su Y,Yan R,Duan Z,Norris JL,Wang L,Jiang Y,Xing W,Chen Y,Xiao Y,Li L,Tao J,Wang N

    更新日期:2013-03-01 00:00:00