Detection of human cytomegalovirus DNA in perilymph of patients with sensorineural hearing loss using real-time PCR.

abstract：:Five temperature-sensitive mutants (tsm9, tsm13, tsm20, tsm22, tsm30) of murine cytomegalovirus have been shown previously not to produce infectious virus in mice. In the present study, the stage at which these mutants are blocked in their replication in vitro was examined by transcriptional analysis of 4 temporally r...

journal_title：Journal of medical virology

authors： Gill TA,Morley PJ,Sweet C

更新日期：2000-10-01 00:00:00

abstract：:The Balkan Peninsula and Bulgaria in particular, is a well-known endemic region for Crimean-Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases of CCHF disease in humans. These ...

journal_title：Journal of medical virology

authors： Gergova I,Kunchev M,Kamarinchev B

更新日期：2012-04-01 00:00:00

abstract：:The increased incidence of a enterovirus infections observed in patients with type 1 diabetes preceding the development of the clinical disease could be partially explained by variation in the genes coding for enterovirus receptors. We carried out sequence analysis of the most common enterovirus receptor molecules in ...

journal_title：Journal of medical virology

authors： Karttunen A,Pöyry T,Vaarala O,Ilonen J,Hovi T,Roivainen M,Hyypiä T

更新日期：2003-05-01 00:00:00

abstract：:Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks i...

journal_title：Journal of medical virology

authors： Feeney SA,Mitchell SJ,Mitchell F,Wyatt DE,Fairley D,McCaughey C,Coyle PV,O'Neill HJ

更新日期：2006-08-01 00:00:00

abstract：:Adhesion molecules are essential for the immune response. They are involved in the regulation of cell-to-cell contact, thereby enabling leukocytes to communicate. Circulating forms of adhesion molecules are found in the serum of healthy individuals. Raised levels have been associated with disease severity in HCV and o...

journal_title：Journal of medical virology

authors： Murgue B,Cassar O,Deparis X

更新日期：2001-09-01 00:00:00

abstract：:A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells, herpesvirus nucle...

journal_title：Journal of medical virology

authors： Arao Y,Soushi S,Sato Y,Moriishi E,Ando Y,Yamada M,Padilla J,Uno F,Nii S,Kurata T

更新日期：1997-10-01 00:00:00

abstract：:Although occult hepatitis B virus (HBV) infection in individuals without detectable hepatitis B surface antigen (HBsAg) may occur and has been reported to be common in patients with chronic hepatitis C, the related molecular mechanisms remain unknown. With the polymerase chain reaction, serum HBV DNA was sought in 100...

journal_title：Journal of medical virology

authors： Kao JH,Chen PJ,Lai MY,Chen DS

更新日期：2002-10-01 00:00:00

abstract：:The Markov model was introduced to simulate natural histories of hepatitis C virus (HCV) infection in men and women. The data set was constructed on 942 HCV carriers who were examined at least once a year without receiving antiviral therapies. Based on 2,251 patient-year data, the probabilities of transition between a...

journal_title：Journal of medical virology

authors： Tanaka J,Kumada H,Ikeda K,Chayama K,Mizui M,Hino K,Katayama K,Kumagai J,Komiya Y,Miyakawa Y,Yoshizawa H

更新日期：2003-07-01 00:00:00

abstract：:Annual outbreaks of seasonal influenza cause a substantial health burden. The aim of this study was to compare patient demographic/clinical data in two influenza patient groups presenting to hospital; those requiring O2 or critical care admission and those requiring less intensive treatment. The study was conducted fr...

journal_title：Journal of medical virology

authors： Dominic C,Welch C,Melzer M

更新日期：2020-07-31 00:00:00

abstract：:Cervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report age-standardized rates of 6.3/10(5) in the central region, 5.4/10(5) in the north, and 2.7/10(5) in the south. High-risk human papillomavirus (HPV) types and their variants di...

journal_title：Journal of medical virology

authors： KrennHrubec K,Mrad K,Sriha B,Ben Ayed F,Bottalico DM,Ostolaza J,Smith B,Tchaikovska T,Soliman AS,Burk RD

更新日期：2011-04-01 00:00:00

abstract：:We report a male caucasian German pediatric patient of no Arab or Mediterranean ancestry with virus associated CNS lesions in Griscelli's syndrome (GS; McKusick No. 214450). The boy presented with recurrent infections, and meningitis with subsequent progressive signs of increased intracranial pressure leading to death...

journal_title：Journal of medical virology

authors： Wagner M,Müller-Berghaus J,Schroeder R,Sollberg S,Luka J,Leyssens N,Schneider B,Krueger GR

更新日期：1997-11-01 00:00:00

abstract：:To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

journal_title：Journal of medical virology

authors： Tateishi J,Tsuji S

更新日期：1985-05-01 00:00:00

abstract：:One hundred twelve peripheral blood specimens were tested for the presence of cytomegalovirus (CMV) by the tube culture indirect immunoperoxidase (TC-IPA) procedure, the shell vial assay [shell vials were pre- and postinoculation treated with medium containing 2 of 10% fetal bovine serum (FBS) or 100 micrograms% corti...

journal_title：Journal of medical virology

authors： Lipson SM,Kaplan MH,Simon JK,Ciamician Z,Tseng LF

更新日期：1992-09-01 00:00:00

abstract：:Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...

journal_title：Journal of medical virology

authors： Cai J,Lv H,Lin J,Chen Z,Fang C,Han J

更新日期：2014-09-01 00:00:00

abstract：:To elucidate the mechanism of heterologous antibody responses to herpes simplex virus (HSV) and varicella-zoster virus (VZV) which occur in some patients with HSV or VZV infections, stronger evidence was sought for the existence of cross-reacting antibodies to these viruses, using antibody absorption procedures. Absor...

journal_title：Journal of medical virology

authors： Schmidt NJ

更新日期：1982-01-01 00:00:00

abstract：:Faeces from 746 children less than 5 years old with acute gastroenteritis were screened for the presence of adenovirus particles or antigens by immunoelectron microscopy (IEM) and enzyme immunoassay (EIA). Thirty-five samples were positive by both IEM and EIA, two only by IEM, and two only by EIA, giving a total of 39...

journal_title：Journal of medical virology

authors： Leite JP,Pereira HG,Azeredo RS,Schatzmayr HG

更新日期：1985-02-01 00:00:00

abstract：:A cDNA copy of the HCV229E nucleocapsid protein gene was isolated and characterized. Sequence analysis predicts a nucleocapsid polypeptide of 389 amino acids with a molecular weight (mol. wt.) of 43,450. Single strand RNA probes derived from the cDNA copy hybridize specifically to HCV229E RNA and approximately 50 pg o...

journal_title：Journal of medical virology

authors： Myint S,Harmsen D,Raabe T,Siddell SG

更新日期：1990-06-01 00:00:00

abstract：:Henan, China is characterized by the outbreak of HIV epidemic of Thai B strain in former plasma donors in 1990s. After the forbidden of paid blood donation, whether Thai B strain will spread out of former plasma donors into sexual transmitted population is unknown. To answer the question, phylogenetic analysis was use...

journal_title：Journal of medical virology

authors： Li L,Sun G,Zhong P,Han J,Li T,Jia D,Liu Y,Sun C,Wang Z,Li H,Wang X,Li J

更新日期：2016-04-01 00:00:00

abstract：:The JC virus (JCV) is a common human virus persisting in renal tissue. In immunocompromised individuals it may reactivate and cause progressive multifocal leukoencephalopathy (PML). JCV has also been implicated in cancerogenesis, leading to various brain tumors and cancers of gastrointestinal tract. In this study the ...

journal_title：Journal of medical virology

authors： Kmieciak D,Debicki S,Trzeciak WH

更新日期：2008-06-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects),...

journal_title：Journal of medical virology

authors： Ferrante P,Caldarelli-Stefano R,Omodeo-Zorini E,Cagni AE,Cocchi L,Suter F,Maserati R

更新日期：1997-07-01 00:00:00

abstract：:Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true HPV prevalence in normal and neoplasic oropharyngeal mucosa remains uncertain. To determine the pre...

journal_title：Journal of medical virology

authors： do Sacramento PR,Babeto E,Colombo J,Cabral Ruback MJ,Bonilha JL,Fernandes AM,Pereira Sobrinho JS,de Souza FP,Villa LL,Rahal P

更新日期：2006-05-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

journal_title：Journal of medical virology

authors： Ren L,Xiao Q,Zhou L,Xia Q,Liu E

更新日期：2015-01-01 00:00:00

abstract：:Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...

journal_title：Journal of medical virology

authors： Druce J,Tran T,Kelly H,Kaye M,Chibo D,Kostecki R,Amiri A,Catton M,Birch C

更新日期：2005-01-01 00:00:00

abstract：:The Gaza Strip borders the southern part of Israel and Egypt. There is a remarkable difference in the prevalence of antibodies to hepatitis C virus (HCV) between Israel (0.5%) and Egypt (10%). A few thousand inhabitants cross the borders daily from the Gaza Strip to both countries. The objectives of this study were to...

journal_title：Journal of medical virology

authors： Shemer-Avni Y,el Astal Z,Kemper O,el Najjar KJ,Yaari A,Hanuka N,Margalith M,Sikuler E

更新日期：1998-11-01 00:00:00

abstract：:Patients with acquired immunodeficiency syndrome (AIDS) commonly suffer from opportunistic infections associated with members of the herpes virus family. To investigate whether certain of these other viruses might have an effect on the ability of the human immunodeficiency virus type 1 (HIV-1) to replicate, we coincub...

journal_title：Journal of medical virology

authors： Tremblay M,Gornitsky M,Wainberg MA

更新日期：1989-10-01 00:00:00

abstract：:The recent emergence of coronavirus disease 2019 (COVID-19) pandemic has reassessed the usefulness of historic convalescent plasma transfusion (CPT). This review was conducted to evaluate the effectiveness of CPT therapy in COVID-19 patients based on the publications reported till date. To our knowledge, this is the f...

journal_title：Journal of medical virology

authors： Rajendran K,Krishnasamy N,Rangarajan J,Rathinam J,Natarajan M,Ramachandran A

更新日期：2020-09-01 00:00:00

abstract：:Our studies of rotavirus challenge in adult volunteers enabled us to evaluate the relationship of pre-existing antirotavirus fecal IgA antibody to infection and illness and to investigate the local response to this infection. No relationship could be found between the pre-existing levels of fecal antirotavirus IgA ant...

journal_title：Journal of medical virology

authors： Bernstein DI,Ziegler JM,Ward RL

更新日期：1986-12-01 00:00:00

abstract：:Knowledge of the precise timing of SARS-CoV-2 infection may be of clinical and epidemiological relevance. The presence of low-avidity IgGs has conventionally been considered an indicator of recent infection. Here, we carried out qualitative assessment of SARS-CoV-2-specific antibody avidity using an urea (6M) dissocia...

journal_title：Journal of medical virology

authors： Valdivia A,Torres I,Huntley D,Alcaraz MJ,Albert E,Colomina J,Ferrer J,Carratalá A,Navarro D

更新日期：2021-02-01 00:00:00

abstract：:According to the Joint National Programme on HIV/AIDS (UNAIDS), the northeastern region of India has the highest HIV prevalence in the country. This study was conducted to determine the current HIV-1 molecular epidemiology of Manipur, a state in northeast India. Blood samples from HIV-1 seropositive subjects were coll...

journal_title：Journal of medical virology

authors： Sharma AL,Singh TR,Devi KR,Singh LS

更新日期：2017-06-01 00:00:00

abstract：:The presence of HPV 16 E6*I/E6*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The detection of HPV 16 E6*I/E6*II mRNAs w...

journal_title：Journal of medical virology

authors： Cricca M,Venturoli S,Leo E,Costa S,Musiani M,Zerbini M

更新日期：2009-07-01 00:00:00