Variation in enterovirus receptor genes.

abstract：:The substitution of amino acid (aa) 70 of arginine for glutamine and/or that of aa91 of leucine for methionine in the core protein in patients infected with hepatitis C virus (HCV) genotype 1b is associated with a poor response to pegylated interferon and ribavirin. Factors influencing these substitutions were sought ...

journal_title：Journal of medical virology

authors： Kobayashi M,Akuta N,Suzuki F,Hosaka T,Sezaki H,Kobayashi M,Suzuki Y,Arase Y,Ikeda K,Watahiki S,Mineta R,Iwasaki S,Miyakawa Y,Kumada H

更新日期：2010-01-01 00:00:00

abstract：:To compare characteristics and outcomes of patients who had COVID-19 with Mycoplasma pneumoniae immunoglobulin M (IgM) antibodies to those without M. pneumoniae antibodies. We retrospectively reviewed cases admitted over a 4-week period between 17 March 2020 and 14 April 2020 to the Hoboken University Medical Center, ...

journal_title：Journal of medical virology

authors： Amin D,McKitish K,Shah PS

更新日期：2021-02-01 00:00:00

abstract：:The L1 gene encodes for the major capsid protein of human papillomaviruses (HPV). There is limited information on the polymorphism of L1 for types related to HPV-16. This report explores the polymorphism of L1 in phylogenetically related types 31, 33, and 35 compared to HPV-16. Genital specimens collected from 732 HIV...

journal_title：Journal of medical virology

authors： Cornut G,Gagnon S,Hankins C,Money D,Pourreaux K,Franco EL,Coutlée F,Canadian Women's HIV Study Group.

更新日期：2010-07-01 00:00:00

abstract：:The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and...

journal_title：Journal of medical virology

authors： Mercatelli D,Triboli L,Fornasari E,Ray F,Giorgi FM

更新日期：2020-11-18 00:00:00

abstract：:This study aimed at developing strategies for screening, predicting, and diagnosing intrauterine HBV infection in infants born to HBsAg positive mothers. A total of 1,360 infants born to 1,355 HBsAg positive mothers were followed for 1 year. All newborn infants received active and passive immunization within 24 hr aft...

journal_title：Journal of medical virology

authors： Yin YZ,Zhang J,Wu LL,Zhou J,Zhang PZ,Zhou SS

更新日期：2013-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) genotypes help to tailor the treatment response, but their influence on the disease severity and association with hepatic steatosis is not well understood. The prevalence of HCV genotypes and their correlation with the histopathological severity of liver disease and steatosis in Indian patients...

journal_title：Journal of medical virology

authors： Hissar SS,Goyal A,Kumar M,Pandey C,Suneetha PV,Sood A,Midha V,Sakhuja P,Malhotra V,Sarin SK

更新日期：2006-04-01 00:00:00

abstract：:Individuals infected with HIV have higher circulating Epstein-Barr virus (EBV) DNA load compared to healthy carriers. This study investigated whether level of spontaneous immunoglobulin secreting cells, one of the major hallmarks of HIV infection, is associated with an increase of EBV DNA load in PBMCs and the spontan...

journal_title：Journal of medical virology

authors： Ouedraogo DE,Tuaillon E,Rubbo PA,Bollore K,Foulongne V,Reynes J,Vendrell JP

更新日期：2014-01-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) has become a serious public health problem worldwide. Here, we stratified COVID-19 patients based on their comorbidities to assess their risk of serious adverse outcomes. We collected 856 hospitalized cases diagnosed with COVID-19 from 17 January to 7 February 2020, in Zhejiang Prov...

journal_title：Journal of medical virology

authors： Ye C,Zhang S,Zhang X,Cai H,Gu J,Lian J,Lu Y,Jia H,Hu J,Jin C,Yu G,Zhang Y,Sheng J,Yang Y

更新日期：2020-11-01 00:00:00

abstract：:A modified centrifugation culture technique and a polymerase chain reaction (PCR) is described for detection of early antigen and IE antigen DNA, respectively, for rapid and sensitive monitoring of active cytomegalovirus (HCMV) infection after organ transplantation. In a preliminary study, 541 clinical specimens (bloo...

journal_title：Journal of medical virology

authors： Prösch S,Kimel V,Dawydowa I,Krüger DH

更新日期：1992-12-01 00:00:00

abstract：:Prophylactic antiviral therapy is recommended for hepatitis B virus (HBV)-infected patients with malignancies who are undergoing systemic chemotherapy. In the current study, we aimed to develop a risk scoring system to guide the selection of prophylactic antiviral agents. In this retrospective analysis, we included co...

journal_title：Journal of medical virology

authors： Kim HY,Yoo JJ,Oh S,Yu SJ,Kim YJ,Yoon JH,Kim W,Jung YJ,Kim BH,Kim CM,Park JW,Lee JH

更新日期：2018-10-01 00:00:00

abstract：:Some aspects of rotavirus humoral immunity were assessed on the basis of distinguishing serotype-specific specificities (VP4/VP7) by using rotavirus reassortants, human and animal strains in neutralization assays in serum samples obtained during the acute phase, and 1, 6 and 12 months after primary natural infection. ...

journal_title：Journal of medical virology

authors： Rojas AM,Boher Y,Guntiñas MJ,Pérez-Schael I

更新日期：1995-12-01 00:00:00

abstract：:The infectivity titer of a standard stock of the SAR-55 strain of hepatitis E virus (HEV) was determined in cynomolgus macaques (Macaca fascicularis) and the effect of dose on the course of the infection was examined by weekly monitoring of alanine aminotransferase (ALT) and anti-HEV levels. Antibody to HEV (anti-HEV)...

journal_title：Journal of medical virology

authors： Tsarev SA,Tsareva TS,Emerson SU,Yarbough PO,Legters LJ,Moskal T,Purcell RH

更新日期：1994-06-01 00:00:00

abstract：:Men who have sex with men (MSM) are an important risk group for human immunodeficiency virus (HIV) and at high-risk of herpesvirus infection. However, limited information on epidemiologic patterns of HHV8 and HSV2 among MSM is available in mainland China. A cross-sectional study of 486 participants was performed in Sh...

journal_title：Journal of medical virology

authors： Liu Z,Fang Q,Zuo J,Wang J,Chen Y,Minhas V,Wood C,He N,Zhang T

更新日期：2017-05-01 00:00:00

abstract：:The specificity and neutralizing activity of antibodies against the major herpes simplex virus type 1 (HSV-1) glycoproteins were tested in serum samples of patients with a history of HSV-1 infection. By preabsorption of sera to preparations of native and denatured HSV-1 proteins, followed by immunoblotting and microne...

journal_title：Journal of medical virology

authors： Eing BR,Kühn JE,Braun RW

更新日期：1989-01-01 00:00:00

abstract：:A highly sensitive two-step polymerase chain reaction (PCR) method was evaluated for detection of human immunodeficiency virus type 1 (HIV-1) DNA in clinical specimens. The product resulting from the first amplification reaction is used as the template for the second PCR with an internal (nested) primer pair. Even whe...

journal_title：Journal of medical virology

authors： Zazzi M,Romano L,Brasini A,Valensin PE

更新日期：1992-11-01 00:00:00

abstract：:The purpose of this study was to investigate determinants of endemic hepatitis C virus (HCV) infection within communities in Taiwan. A two-phase study, including a seroprevalence survey and a prevalent case-control study at the first phase, which has been published previously, and a follow-up seroconversion determinat...

journal_title：Journal of medical virology

authors： Sun CA,Chen HC,Lu SN,Chen CJ,Lu CF,You SL,Lin SH

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：:An efficient method for cloning subgenomic fragments of the hepatitis B virus (HBV) was developed, utilizing its abundant single-stranded replicative intermediates. The total genomic DNA obtained from the liver tissue of patients with chronic HBV infection was treated by using the Klenow fragment of E. coli DNA polyme...

journal_title：Journal of medical virology

authors： Kajino K,Ohta Y,Miyamura T,Saito I

更新日期：1991-01-01 00:00:00

abstract：:To define better the human immune response to individual structural proteins of human cytomegalovirus (HCMV), 55 human sera with different IgG and IgM titres were studied for their reactivity with HCMV structural polypeptides separated by SDS-PAGE and electrotransferred to nitrocellulose paper. The results obtained sh...

journal_title：Journal of medical virology

authors： Landini MP,Re MC,Mirolo G,Baldassarri B,La Placa M

更新日期：1985-12-01 00:00:00

abstract：:A common causative agent for uterine cervical cancer is the human papillomavirus type 18 (HPV-18) which has three phylogenic variants: Asian-Amerindian, European, and African. Each variant shows significant molecular differences in the E6 gene. E6 oncoprotein is a negative regulator of tumor suppressor protein p53, he...

journal_title：Journal of medical virology

authors： Vazquez-Vega S,Sanchez-Suarez LP,Andrade-Cruz R,Castellanos-Juarez E,Contreras-Paredes A,Lizano-Soberon M,Garcia-Carranca A,Benitez Bribiesca L

更新日期：2013-07-01 00:00:00

abstract：:Tumor necrosis factor receptor superfamily member 10 (TNFRSF10) is a death domain-containing receptor for the apoptotic ligand TNFSF10, which involves multiple processes, including hepatocarcinogenesis and immune response against HBV infection. Several single nucleotide polymorphisms (SNPs) were identified as expressi...

journal_title：Journal of medical virology

authors： Wen J,Song C,Liu J,Chen J,Zhai X,Hu Z

更新日期：2016-03-01 00:00:00

abstract：:To establish gut immunity in monkeys to polio-virus type 1, we fed four juvenile bonnet monkeys (Macaca radiata) with 100 median infectious doses of the Mahoney strain of virus. The duration of viral shedding in the throat and faeces and the titre of virus in faeces were measured. Eighteen days after the last monkey s...

journal_title：Journal of medical virology

authors： Selvakumar R,John TJ

更新日期：1989-02-01 00:00:00

abstract：:To determine the influence of ageing per se as well as of priming histories on the antibody response to influenza vaccination, haemagglutination inhibition (HI), ELISA IgG, IgA, IgM and neutralizing antibody titres were studied in 43 healthy young subjects (mean age 23 years) and 55 healthy elderly people (mean age 79...

journal_title：Journal of medical virology

authors： Remarque EJ,de Bruijn IA,Boersma WJ,Masurel N,Ligthart GJ

更新日期：1998-05-01 00:00:00

abstract：:Polyomavirus infection occurring during childhood is followed by a lifelong latency in immunocompetent subjects. The major site of polyomavirus persistence are the uroepithelial cells which leads to oral transmission. It has recently been hypothesized that tonsils could be a possible reservoir. The role of tonsil, ade...

journal_title：Journal of medical virology

authors： Comar M,Zanotta N,Bovenzi M,Campello C

更新日期：2010-07-01 00:00:00

abstract：:Epstein-Barr virus (EBV) genotypes can be distinguished based on gene sequence differences in EBV nuclear antigens 2, 3A, 3B, and 3C, and the BZLF1 promoter zone (Zp). EBV subtypes and BZLF1 Zp variants were examined in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated h...

journal_title：Journal of medical virology

authors： Imajoh M,Hashida Y,Murakami M,Maeda A,Sato T,Fujieda M,Wakiguchi H,Daibata M

更新日期：2012-06-01 00:00:00

abstract：:During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isola...

journal_title：Journal of medical virology

authors： Lim CS,Chan KP,Goh KT,Chow VT

更新日期：2003-06-01 00:00:00

abstract：:Enteric adenoviruses are important etiological agents associated with sporadic infections and outbreaks of acute gastroenteritis in infants and children. Fecal samples were collected from 439 hospitalized patients in the years 2005-2007 from Pune, Aurangabad, and Nagpur cities of western India to identify the most pre...

journal_title：Journal of medical virology

authors： Verma H,Chitambar SD,Varanasi G

更新日期：2009-01-01 00:00:00

abstract：:Nasal washings were collected from 27 normal adults during 38 naturally acquired colds. The washings were exhaustively tested using tissue cultures, organ cultures and electron microscopy. Washings yielding no identifiable agent were inoculated into human volunteers, and further specimens obtained from the latter were...

journal_title：Journal of medical virology

authors： Larson HE,Reed SE,Tyrrell DA

更新日期：1980-01-01 00:00:00

abstract：:Analysis of the HIV-1 V3 quasispecies present in an individual at the time of seroconversion was carried out. The polymerase chain reaction (PCR) was used to amplify proviral HIV-1 DNA extracted from peripheral blood mononuclear cells from a patient who was viraemic (p24 = 15 pg/ml) and had an equivocal HIV-1 antibody...

journal_title：Journal of medical virology

authors： Ait-Khaled M,Emery VC

更新日期：1993-12-01 00:00:00

abstract：:Enterovirus D68 (EV-D68) is an emergent viral pathogen associated with mild to severe respiratory infections. In this study, we describe respiratory infections associated with EV-D68 in Beijing over a 4 year period. Total nucleic acid was extracted from 7,945 clinical specimens collected between January 5, 2011 and Ju...

journal_title：Journal of medical virology

authors： Zhang T,Li A,Chen M,Wu J,Huang F

更新日期：2016-09-01 00:00:00