Total HCV core antigen assay: a new marker of hepatitis C viremia for monitoring the progress of therapy.

abstract：:Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were i...

journal_title：Journal of medical virology

authors： Hashimoto Y,Ochi H,Abe H,Hayashida Y,Tsuge M,Mitsui F,Hiraga N,Imamura M,Takahashi S,Nelson Hayes C,Ohishi W,Kubo M,Tsunoda T,Kamatani N,Nakamura Y,Chayama K

更新日期：2011-06-01 00:00:00

abstract：:The effect of interferon-gamma (IFN-gamma) on dengue virus multiplication in human peripheral blood monocytes was investigated. Enriched monocytes were treated with IFN-gamma and then infected with dengue virus type 2 either directly or in the presence of optimal infection-enhancing levels of antibodies. Pretreatment ...

journal_title：Journal of medical virology

authors： Sittisombut N,Maneekarn N,Kanjanahaluethai A,Kasinrerk W,Viputtikul K,Supawadee J

更新日期：1995-01-01 00:00:00

abstract：:Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...

journal_title：Journal of medical virology

authors： Kobayashi M,Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Suzuki F,Akuta N,Someya T,Matsuda M,Sato J,Takagi K,Miyakawa Y,Kumada H

更新日期：2002-12-01 00:00:00

abstract：:The tandem direct reiteration R1 in the varicella-zoster virus genome consists of two elements: units composed of 18 bp and those having 15 bp, both of whose numbers and types of combination patterns vary among strains. The variations of the R1 structure were examined in order to differentiate between the wild strains...

journal_title：Journal of medical virology

authors： Yoshida M,Tamura T,Hiruma M

更新日期：1999-05-01 00:00:00

abstract：:Polyomavirus BK (BKV) is a common human polyomavirus that rarely causes clinical symptoms in immunocompetent individuals. However, BK virus reactivation occurs in 20-40% of kidney transplant patients and 1-10% of cases present with BK virus-associated nephropathy (BKVN) and reduced kidney allograft survival. In this s...

journal_title：Journal of medical virology

authors： Girmanova E,Brabcova I,Bandur S,Hribova P,Skibova J,Viklicky O

更新日期：2011-08-01 00:00:00

abstract：:The reliability of the polymerase chain reaction (PCR) for prenatal diagnosis of human cytomegalovirus (HCMV) infection was determined by retrospective testing of 35 amniotic fluids identified previously as positive or negative for HCMV by virus isolation. Amniocentesis was performed in 26 pregnant women with primary ...

journal_title：Journal of medical virology

authors： Revello MG,Baldanti F,Furione M,Sarasini A,Percivalle E,Zavattoni M,Gerna G

更新日期：1995-12-01 00:00:00

abstract：:The specificity and neutralizing activity of antibodies against the major herpes simplex virus type 1 (HSV-1) glycoproteins were tested in serum samples of patients with a history of HSV-1 infection. By preabsorption of sera to preparations of native and denatured HSV-1 proteins, followed by immunoblotting and microne...

journal_title：Journal of medical virology

authors： Eing BR,Kühn JE,Braun RW

更新日期：1989-01-01 00:00:00

abstract：:During 2002, several epidemics of aseptic meningitis were attributed to echovirus 13 in Korea. The causative agents of these outbreaks were isolated and identified using rhabdosarcoma cells, HEp-2 and Buffalo green monkey kidney cells, and a neutralization test using monospecific antiserum. Fifty-four echovirus 13 iso...

journal_title：Journal of medical virology

authors： Cheon DS,Lee J,Lee K,Lee S,Park K,Ahn J,Jee Y,Yoon J,Cho H

更新日期：2004-07-01 00:00:00

abstract：:HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC ...

journal_title：Journal of medical virology

authors： Natarajan V,Kottilil S,Hazen A,Adelsberger J,Murphy AA,Polis MA,Kovacs JA

更新日期：2010-12-01 00:00:00

abstract：:Interaction between herpesviruses and human immunodeficiency virus (HIV)1 is postulated in the progression of HIV disease. In order to evaluate the specific antibody responses directed to Epstein-Barr virus (EBV) and cytomegalovirus (CMV) and to provide serological evidence suggesting reactivation of these viruses abl...

journal_title：Journal of medical virology

authors： Quesnel A,Pozzetto B,Touraine F,Moja P,Lucht F,De The G,Touraine JL,Gaudin O,Genin C

更新日期：1992-01-01 00:00:00

abstract：:Enteroviruses (EVs) are RNA viruses that can cause many clinical syndromes including acute flaccid paralysis (AFP). Within the global polio laboratory network, EVs are categorized either as polioviruses or non-polio enteroviruses (NPEVs). Specific NPEVs have been described in polio-like residual paralytic events in AF...

journal_title：Journal of medical virology

authors： Tushabe P,Howard W,Bwogi J,Birungi M,Eliku JP,Kakooza P,Bukenya H,Namuwulya P,Gaizi J,Tibanagwa M,Kabaliisa T,Mulindwa J,Muhanguzi D,Suchard M,Gumede N,Bakamutumaho B

更新日期：2021-01-17 00:00:00

abstract：:Hantaviruses is an emerging infectious disease. Although HCPS has been reported in several regions of Brazil, more cases of HCPS have recently been reported in Minas Gerais than in any other state. In 2009, we analyzed 27 samples presenting antibodies against hantaviruses. These samples originated from 688 symptomatic...

journal_title：Journal of medical virology

authors： de Araujo J,Duré AI,Negrão R,Ometto T,Thomazelli LM,Durigon EL

更新日期：2015-05-01 00:00:00

abstract：:Intramuscular (IM) influenza vaccines are about 50% effective in preventing clinical illness among the elderly and their effectiveness in eliciting mucosal response may be even lower. The aim of the present study was to evaluate the immunological effect of a novel inactivated intranasal (IN) trivalent whole influenza ...

journal_title：Journal of medical virology

authors： Muszkat M,Yehuda AB,Schein MH,Friedlander Y,Naveh P,Greenbaum E,Schlesinger M,Levy R,Zakay-Rones Z,Friedman G

更新日期：2000-05-01 00:00:00

abstract：:B-cells play an important role in defending children against various infections. In view of scare data, we undertook this prospective cohort study to describe B cell compartment in HIV infected children (<5 years of age) and the effect of HAART on B cell subpopulations. HIV infected children (<5 years) from Pediatric ...

journal_title：Journal of medical virology

authors： Singh R,Mukherjee A,Singla M,Vajpayee M,Negi N,Kabra SK,Lodha R,Das BK

更新日期：2018-07-01 00:00:00

abstract：:The S RNA genome segment of hantaviruses carried by Arvicolinae and Sigmodontinae rodents encodes the nucleocapsid (N) protein and has an overlapping (+1) open reading frame (ORF) for a putative nonstructural protein (NSs). The aim of this study was to determine whether the ORF is functional. A protein corresponding t...

journal_title：Journal of medical virology

authors： Jääskeläinen KM,Kaukinen P,Minskaya ES,Plyusnina A,Vapalahti O,Elliott RM,Weber F,Vaheri A,Plyusnin A

更新日期：2007-10-01 00:00:00

abstract：:Our studies of rotavirus challenge in adult volunteers enabled us to evaluate the relationship of pre-existing antirotavirus fecal IgA antibody to infection and illness and to investigate the local response to this infection. No relationship could be found between the pre-existing levels of fecal antirotavirus IgA ant...

journal_title：Journal of medical virology

authors： Bernstein DI,Ziegler JM,Ward RL

更新日期：1986-12-01 00:00:00

abstract：:The discovery of acyclovir marked the beginning of an exciting era in antiviral research. Early studies on the novel mode of action explained the selectivity of the compound and the remarkably narrow spectrum of activity against a subset of the herpesviruses. Throughout the past decade many clinical trials have demons...

journal_title：Journal of medical virology

authors： Darby G

更新日期：1993-01-01 00:00:00

abstract：:A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

journal_title：Journal of medical virology

authors： Tay N,Chan SH,Ren EC

更新日期：1990-04-01 00:00:00

abstract：:The role of a novel virus, designated as TT virus (TTV), as a cause of chronic liver disease has not been well defined. We investigated the prevalence of TTV among 69 patients with chronic liver disease of unknown etiology and 50 volunteer blood donors with normal transaminase levels. TTV DNA was amplified by polymera...

journal_title：Journal of medical virology

authors： Nishiguchi S,Enomoto M,Shiomi S,Tanaka M,Fukuda K,Tamori A,Tanaka T,Takeda T,Seki S,Yano Y,Otani S,Kuroki T

更新日期：2000-11-01 00:00:00

abstract：:We have tested a multiplex polymerase chain reaction (PCR) human papillomavirus (HPV) genotyping assay to fill the need for rapid and low-cost HPV detection in Sub-Saharan Africa. This method allows high throughput genotyping and simultaneous detection of 14 high-risk and two low-risk HPV types, by PCR amplification o...

journal_title：Journal of medical virology

authors： Samwel K,Kahesa C,Mwaiselage J,Gonzalez D,West JT,Wood C,Palefsky J,Angeletti PC

更新日期：2019-02-01 00:00:00

abstract：:To report the clinical characteristics and potential risk factors of patients with coronavirus disease 2019 (COVID-19) in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID-19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic re...

journal_title：Journal of medical virology

authors： Shu L,Wang X,Li M,Chen X,Ji N,Shi L,Wu M,Deng K,Wei J,Wang X,Cao Y,Yan J,Feng G

更新日期：2021-02-01 00:00:00

abstract：:Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...

journal_title：Journal of medical virology

authors： Marra E,King A,van Logchem E,van der Weele P,Mooij SH,Heijman T,Meijer CJLM,Verhagen DWM,van der Sande MAB,Schim van der Loeff MF

更新日期：2018-01-01 00:00:00

abstract：:The evidence on genotype-specific risk in women infected with human papillomavirus (HPV) with normal cytology and the importance of the distinction of high-risk (HR)-HPV genotypes in the management of low-grade lesions suggest that the distinction of HR-HPV genotypes has the potential to improve the follow-up of patie...

journal_title：Journal of medical virology

authors： Venturoli S,Ambretti S,Cricca M,Leo E,Costa S,Musiani M,Zerbini M

更新日期：2008-08-01 00:00:00

abstract：:The prevention of mother to child transmission of HIV-1 by zidovudine monotherapy is well known, but increasingly combination anti-retroviral therapy is prescribed during pregnancy. In this prospective study, 19 pregnant women with human immunodeficiency virus-1 (HIV-1) infection who elected to take anti-retroviral th...

journal_title：Journal of medical virology

authors： Clarke JR,Braganza R,Mirza A,Stainsby C,Ait-Khaled M,Wright A,Lyall H,Parker D,McClure MO,Weber JN,Taylor GP

更新日期：1999-11-01 00:00:00

abstract：:The plaque reduction neutralization test (PRNT) has been used routinely in serological studies with such arenaviruses as Junin, Machupo, and Parana. However, difficulties have been encountered in using the PRNT for LCM virus, while conflicting views have been expressed about the reliability and efficacy of the test wi...

journal_title：Journal of medical virology

authors： Tomori O,Johnson KM,Kiley MP,Elliott LH

更新日期：1987-05-01 00:00:00

abstract：:Human parainfluenza viruses (HPIVs) are an important cause of acute lower respiratory tract infections (ALRTIs). HPIV-4, a newly identified virus, has been associated with severe ALRTIs recently. A total of 771 nasopharyngeal aspirate samples were collected from hospitalized children between March 2010 and February 20...

journal_title：Journal of medical virology

authors： Xiao NG,Duan ZJ,Xie ZP,Zhong LL,Zeng SZ,Huang H,Gao HC,Zhang B

更新日期：2016-12-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...

journal_title：Journal of medical virology

authors： Cholongitas E,Papatheodoridis GV,Manesis EK,Petraki K,Tiniakos D,Hadziyannis SJ

更新日期：2011-07-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Sera from 1,943 individuals from Auckland, New Zealand, were tested for the presence of serum antibodies to human T cell lymphotropic virus I (HTLV I), mainly with an enzyme-linked immunosorbent assay (ELISA) with cell extracts as target antigen. The individuals tested were blood donors and mostly Caucasian, but inclu...

journal_title：Journal of medical virology

authors： Reddy D,Okochi K,Woodfield DG,Judd W

更新日期：1987-08-01 00:00:00