Detection of viruses in weekly stool specimens collected during the first 2 years of life: A pilot study of five healthy Australian infants in the rotavirus vaccine era.

Abstract:

:Several viruses are associated with gastroenteritis in infants. This pilot study, nested within a larger community-based project of early childhood infections, collected daily symptom data and 511 weekly stool samples from five healthy, fully vaccinated, term infants from birth until their second birthday. Real-time PCR assays were used to detect six enteric viruses. Frequent, silent shedding of one or more of the six viruses was observed, particularly involving adenovirus where shedding could be for up to 3 months without gastrointestinal symptoms. These pilot data demonstrate that a positive PCR result for enteric viruses may not always indicate the cause of childhood gastroenteritis. J. Med. Virol. 89:917-921, 2017. © 2016 Wiley Periodicals, Inc.

journal_name

J Med Virol

authors

Ye S,Whiley DM,Ware RS,Sloots TP,Kirkwood CD,Grimwood K,Lambert SB

doi

10.1002/jmv.24716

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

917-921

issue

5

eissn

0146-6615

issn

1096-9071

journal_volume

89

pub_type

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