Role of Calomys musculinus peritoneal macrophages in age-related resistance to Junin virus infection.

Abstract:

:In nature, the cricetid Calomys musculinus is the principal host of Junin virus, the etiological agent of Argentine hemorrhagic fever. In the experimental infection, adult C. musculinus survived whereas newborns died after intraperitoneal inoculation with the XJ.Cl3 strain of Junin virus. The role of peritoneal macrophages in this age-related resistance was studied. Junin virus multiplied in cultivated macrophages from either neonatal or adult animals and, therefore, it was not possible to correlate the susceptibility of peritoneal macrophages to Junin virus infection with the age-dependent resistance. When adult and neonatal animals were treated with silica prior to Junin virus infection, deaths occurred in the adults, while a delay and decrease in the mortality rate were observed in neonatals. These results suggest that in neonatal C. musculinus macrophages could be permissive cells for Junin virus multiplication, whereas in adult cricetids, these cells would act as a barrier against viral infection by means of an extrinsic antiviral activity.

journal_name

J Med Virol

authors

Coulombié FC,Alché LE,Lampuri JS,Coto CE

doi

10.1002/jmv.1890180311

subject

Has Abstract

pub_date

1986-03-01 00:00:00

pages

289-98

issue

3

eissn

0146-6615

issn

1096-9071

journal_volume

18

pub_type

杂志文章
  • Frequent detection of cell-associated HIV-1 RNA in patients with plasma viral load

    abstract::Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20993

    authors: Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

    更新日期:2007-10-01 00:00:00

  • Unexpected detection of simian SA11-human reassortant strains of rotavirus G3P[8] genotype from diarrhea epidemic among tribal children of Western India.

    abstract::This investigation is in continuation with the earlier studies on diarrhea epidemic due to rotavirus, that occurred at Jawhar western India, among tribal children during Dec 2000-Jan 2001 published by National Institute of Virology, Pune. Three rotavirus strains were isolated in cell culture from fecal specimens of af...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20425

    authors: Awachat PS,Kelkar SD

    更新日期:2005-09-01 00:00:00

  • Infection with GB virus C/hepatitis G virus among blood donors and hemophiliacs in Martinique, a Caribbean island.

    abstract::GB virus C/hepatitis G virus (GBV-C/HGV) RNA was detected by reverse transcription-polymer- ase chain reaction with primers derived from the nonstructural region 3 (NS3) in 9 (4.1%) of 221 blood donors and 2 of 20 (10%) hemophilia patients in Martinique, French West Indies. Anti-E2 antibodies were found in sera from 3...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Césaire R,Martial J,Maier H,Kerob-Bauchet B,Bera O,Duchaud E,Brebion A,Pierre-Louis S

    更新日期:1999-10-01 00:00:00

  • Influence of HCV genotype and co-infection with human immunodeficiency virus on CD4(+) and CD8(+) T-cell responses to hepatitis C virus.

    abstract::The role of T-cells in clearance of hepatitis C virus (HCV) during acute infection is critical. The relevance of the immunological response in the control of HCV replication is less clear in chronic HCV infection. HCV-specific T-cell responses were examined in 92 interferon-naive individuals with chronic hepatitis C. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20856

    authors: Capa L,Soriano V,García-Samaniego J,Nuñez M,Romero M,Cascajero A,Muñoz F,González-Lahoz J,Benito JM

    更新日期:2007-05-01 00:00:00

  • Excretion of the novel polyomaviruses KI and WU in the stool of patients with hematological disorders.

    abstract::Infection with human polyomaviruses BKV and JCV is asymptomatic, and lifelong and widespread, among the general population. However, in the setting of immunosuppression, secondary to medications or viral infection, for example, with HIV, reactivation can occur and result in severe disease. In this study, stool specime...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21559

    authors: Babakir-Mina M,Ciccozzi M,Alteri C,Polchi P,Picardi A,Greco F,Lucarelli G,Arcese W,Perno CF,Ciotti M

    更新日期:2009-09-01 00:00:00

  • Gender disparity in distribution of the major hydrophilic region variants of hepatitis B virus genotype C according to hepatitis B e antigen serostatus.

    abstract::Hepatitis B virus (HBV) e antigen (HBeAg) seroconversion during chronic HBV infection is known to play an important role in disease progression and patient response to antiviral agents. The aim of the present study was to analyze gender disparity in distribution of major hydrophilic region (MHR) variants according to ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21988

    authors: Lee SA,Cho YK,Lee KH,Hwang ES,Kook YH,Kim BJ

    更新日期:2011-03-01 00:00:00

  • Cell-mediated immunity in respiratory syncytial virus disease.

    abstract::Systemic cell-mediated responses to respiratory syncytial (RS) virus were detected, using a whole blood transformation assay, in 10 of 28 infants and children with RS virus infections during the period 1-14 days postadmission. Cell-mediated responses were unrelated to the age of the patient or the severity of illness....

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890130112

    authors: Scott R,Pullan CR,Scott M,McQuillin J

    更新日期:1984-01-01 00:00:00

  • Case report: Eastern equine encephalitis virus imported to the UK.

    abstract::Eastern equine encephalitis (EEE) is rare, but the most severe of the mosquito-borne encephalitides in the United States with a high case fatality rate of 30%. Here, we present a patient with EEE. EEE virus causes sporadic human disease in the Eastern parts of the United States, but the case we describe was a Scottish...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21379

    authors: Harvala H,Bremner J,Kealey S,Weller B,McLellan S,Lloyd G,Staples E,Faggian F,Solomon T

    更新日期:2009-02-01 00:00:00

  • Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users.

    abstract::Hepatitis C virus subtype 3a (HCV-3a) originates from Asia and has spread widely among injecting drug users as well as other patient groups in industrialized countries. HCV subtype 3a infection remains highly prevalent and frequently transmitted in the population of intravenous drug users. The objective of this study ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20692

    authors: Morice Y,Cantaloube JF,Beaucourt S,Barbotte L,De Gendt S,Goncales FL,Butterworth L,Cooksley G,Gish RG,Beaugrand M,Fay F,Fay O,Gonzalez JE,Martins RM,Dhumeaux D,Vanderborght B,Stuyver L,Sablon E,de Lamballerie X,Pawl

    更新日期:2006-10-01 00:00:00

  • Seroprevalence against Norwalk-like human caliciviruses in beijing, China.

    abstract::Serum specimens from 1,109 individuals at different ages in Beijing, China, were collected between April 1996 and March 1997 and tested for IgG antibodies against human caliciviruses using enzyme immune assays (EIAs). Baculovirus-expressed recombinant Norwalk virus (rNV) and Mexican virus (rMxV) capsid proteins were u...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(200001)60:1<97::aid-jmv16>

    authors: Jing Y,Qian Y,Huo Y,Wang LP,Jiang X

    更新日期:2000-01-01 00:00:00

  • 9-Nitrocamptothecin inhibits HIV-1 replication in human peripheral blood lymphocytes: a potential alternative for HIV-infection/AIDS therapy.

    abstract::The ability of the anti-cancer drug, 9-Nitrocamptothecin (9NC), to inhibit replication of HIV-1 in clinically relevant primary lymphocytic cells was studied. Primary peripheral blood lymphocytes (PBLs) from a non-infected donor were freshly infected with HIV-1 and treated with 9NC by using three different treatment sc...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1042

    authors: Hung CL,Doniger J,Palini A,Snyder SW,Radonovich MF,Brady JN,Pantazis P,Sadaie MR

    更新日期:2001-07-01 00:00:00

  • Prevalence of HBV, HDV, HCV, and HIV infection during pregnancy in northern Benin.

    abstract::Pregnant women are not screened for HBsAg and anti-HCV antibodies in many African countries. As there are few data concerning the prevalence of HBV, HDV, and HCV serological markers in Benin, the aim of this study was to evaluate their 2011 prevalence in pregnant women undergoing HIV screening in a rural area of north...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23951

    authors: De Paschale M,Ceriani C,Cerulli T,Cagnin D,Cavallari S,Ndayaké J,Zaongo D,Priuli G,Viganò P,Clerici P

    更新日期:2014-08-01 00:00:00

  • Redetection of HBV lamivudine-resistant mutations in a patient under entecavir therapy, who had been treated sequentially with nucleos(t)ide analogues.

    abstract::Development of hepatitis B virus (HBV)-resistant strains following nucleos(t)ide analog treatment is a major medical concern. This report describes a case of an adult patient with chronic HBV infection, sequentially treated with the nucleos(t)ide analogues, lamivudine, adefovir, and entecavir. During monotherapy with ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20982

    authors: Rodriguez-Frias F,Jardi R,Schaper M,Gimferrer M,Elefsiniotis I,Tabernero D,Esteban R,Buti M

    更新日期:2007-11-01 00:00:00

  • Presence of Betapapillomavirus in Kaposi sarcoma lesions.

    abstract::Human herpes virus 8 (HHV 8) is recognized as the necessary cause of Kaposi sarcoma (KS) and in the recent past the human papillomavirus (HPV) has been linked to the development of cutaneous basal cell and squamous cell carcinomas. In a cross sectional study investigating Beta-HPV infections in skin lesions, an unexpe...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23944

    authors: Murahwa AT,Muchemwa FC,Duri K,Borok MZ,Kanyera RB,Manhanzva MT,Mapingure MP,Stray-Pedersen B

    更新日期:2014-09-01 00:00:00

  • Hepatitis A antibodies in attenders of London Travel Clinics: cost-benefit of screening prior to hepatitis A immunisation.

    abstract::The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890440414

    authors: Zuckerman JN,Powell L

    更新日期:1994-12-01 00:00:00

  • Characterization of new epidemic strains of influenza B virus by using neutralizing monoclonal antibodies.

    abstract::During the 1998-1999 influenza season, two distinct influenza B virus Yamagata group strains were isolated from the patients of a private clinic. Each responded differently to monoclonal antibodies (Mabs) 5H4 and 8B3 on staining, and hemagglutination inhibition and neutralizing tests. When the analysis of nucleotide s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2099

    authors: Nakagawa N,Kubota R,Morikawa S,Nakagawa T,Baba K,Okuno Y

    更新日期:2001-12-01 00:00:00

  • Accentuated antibody response to paramyxoviruses in individuals infected with human immunodeficiency virus.

    abstract::Sera from 31 human immunodeficiency virus (HIV)-infected patients, representing different clinical stages of HIV infection, were assayed for antibodies against measles and mumps viruses by various serological tests and compared to 23 healthy controls. Sera from four patients (two primary, one asymptomatic, and one acq...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890260107

    authors: Kövamees J,Sheshberadaran H,Chiodi F,Schwartz S,Orvell C,Fenyö EM,Norrby E

    更新日期:1988-09-01 00:00:00

  • High prevalence of non-B HIV-1 subtypes in seamen and their sexual partners in Croatia.

    abstract::Travel influences the spread of non-B subtypes of HIV in Europe. The aim of this study was to assess whether the spread of non-B subtypes occurred in Croatia, a country with a low level HIV infection. Phylogenetic analysis of the reverse transcriptase and protease genes was undertaken in 145 Croatian patients with the...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21433

    authors: Ramirez-Piedad MK,Lepej SZ,Yerly S,Begovac J

    更新日期:2009-04-01 00:00:00

  • Fulminant demyelinating encephalomyelitis associated with productive HHV-6 infection in an immunocompetent adult.

    abstract::Human herpesvirus 6 (HHV-6), the etiologic agent of roseola in young children, has been reported to be detectable in the brain of many neurologically normal adults, although regional localization to plaques of multiple sclerosis has also been demonstrated. Large amounts of this virus were present in multifocal demyeli...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199707)52:3<301::aid-jmv11

    authors: Novoa LJ,Nagra RM,Nakawatase T,Edwards-Lee T,Tourtellotte WW,Cornford ME

    更新日期:1997-07-01 00:00:00

  • Inactivation of hepatitis A virus by heat treatment in aqueous solution.

    abstract::Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890410113

    authors: Murphy P,Nowak T,Lemon SM,Hilfenhaus J

    更新日期:1993-09-01 00:00:00

  • Analyzing situational awareness through public opinion to predict adoption of social distancing amid pandemic COVID-19.

    abstract::COVID-19 pandemic has affected over 100 countries in a matter of weeks. People's response toward social distancing in the emerging pandemic is uncertain. In this study, we evaluated the influence of information (formal and informal) sources on situational awareness of the public for adopting health-protective behavior...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25840

    authors: Qazi A,Qazi J,Naseer K,Zeeshan M,Hardaker G,Maitama JZ,Haruna K

    更新日期:2020-07-01 00:00:00

  • Hemagglutination inhibition, single radial hemolysis, and ELISA tests for the detection of IgG and IgM to rubella virus.

    abstract::Hemagglutination inhibition (HI), single radial hemolysis (SRH) and enzyme-linked immuno sorbent assay (ELISA), performed with commercial antigen and reagents are described and were compared in the three distinct situations that require rubella antibody detection. Determination of immunity status was carried out on 15...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/1096-9071(1980)5:4<273::aid-jmv1890050403>

    authors: Champsaur H,Dussaix E,Tournier P

    更新日期:1980-01-01 00:00:00

  • Activation of cellular oncogenes by clinical isolates and laboratory strains of human cytomegalovirus.

    abstract::The effect on cellular (c) oncogene RNA levels was investigated after infection of permissive cells with cell culture adapted strains (AD-169, C-87, Davis) and unadapted clinical isolates (82-1, 84-2, 85-1) of human cytomegalovirus (HCMV). The results indicate that both adapted and unadapted strains of HCMV induce sub...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890340409

    authors: Boldogh I,AbuBakar S,Fons MP,Deng CZ,Albrecht T

    更新日期:1991-08-01 00:00:00

  • Serologic and viral genome prevalence of HSV, EBV, and HCMV among healthy adults in Wuhan, China.

    abstract::The worldwide infection rate of herpesvirus is high, but the detailed prevalence in China, especially the central area, remains unclear. In the present study, the prevalence of herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV) was investigated in 303 healthy adults in Wuhan, a repr...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24989

    authors: Wen L,Qiu Y,Cheng S,Jiang X,Ma YP,Fang W,Wang W,Cui J,Ruan Q,Zhao F,Hu F,Luo MH

    更新日期:2018-03-01 00:00:00

  • Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring.

    abstract::Despite the success of antivirals in preventing clinically overt CMV disease in cardiac allograft recipients, sub-clinical active CMV infection remains a major concern because of its association with allograft rejection and vasculopathy. The measurement of CMV specific T-cell responses is a promising approach to asses...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21229

    authors: Kirchner A,Hoffmeister B,Cherepnev-G G,Fuhrmann S,Streitz M,Lachmann R,Bunde T,Meij P,Schönemann C,Hetzer R,Lehmkuhl HB,Volkmer-Engert R,Volk HD,Gratama JW,Kern F

    更新日期:2008-09-01 00:00:00

  • IFNL3 (IL28B) and IFNL4 polymorphisms are associated with treatment response in Thai patients infected with HCV genotype 1, but not with genotypes 3 and 6.

    abstract::Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda-3 (IFNL3 or IL-28B) and IFNL4 genes and treatment response to hepatitis C virus genotype 1 (HCV-1) infection. The importance of these SNPs for HCV genotype 3 (HCV-3), and particularly HCV genotype 6 (HCV-6)...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23957

    authors: Akkarathamrongsin S,Thong VD,Payungporn S,Poovorawan K,Prapunwattana P,Poovorawan Y,Tangkijvanich P

    更新日期:2014-09-01 00:00:00

  • Cervicovaginal synthesis of IgG antibodies to the immunodominant 175-199 domain of the surface glycoprotein gp46 of human T-cell leukemia virus type I.

    abstract::Paired sera, saliva and cervicovaginal secretions from 17 HTLV-I-infected women (19-75 yr) were tested for total IgA and IgG, for IgA and IgG to the immunodominant region gp46/175-Pro-199, for serum IgG to the neutralizing domains gp46/ 190-Pro-199 and gp46/190-Ser-199, or for tax-rex proviral HTLV-DNA. Serum antibodi...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199609)50:1<42::AID-JMV9>3

    authors: Bélec L,Georges-Courbot MC,Georges A,Mohamed AS,Londos-Gagliardi D,Hallouin MC,Hocini H,Guillemain B

    更新日期:1996-09-01 00:00:00

  • Titration of hepatitis B virus infectivity in the sera of pre-acute and late acute phases of HBV infection: transmission experiments to chimeric mice with human liver repopulated hepatocytes.

    abstract::Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21320

    authors: Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

    更新日期:2008-12-01 00:00:00

  • Quantification of adenovirus species B and C viremia by real-time PCR in adults and children undergoing stem cell transplantation.

    abstract::Adenovirus infection during stem cell transplantation is associated with high morbidity and mortality. Adenovirus species B and C have been the main causes for these infections; however, epidemiological details about the species are still unclear. To clarify the contributions of species B and C adenovirus, the DNA was...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20796

    authors: Takayama R,Hatakeyama N,Suzuki N,Yamamoto M,Hayashi T,Ikeda Y,Ikeda H,Nagano H,Ishida T,Tsutsumi H

    更新日期:2007-03-01 00:00:00

  • Differential effect of amantadine hydrochloride on the systemic and local immune response to influenza A.

    abstract::Anti-influenza serum and nasal antibody titers were followed during a double-blind, placebo-controlled, randomized study assessing the prophylactic efficacy of 50, 100, and 200 mg/day of amantadine hydrochloride against experimental challenge with influenza A/Beth/1/85. The geometric mean titers (GMT) of serum hemaggl...

    journal_title:Journal of medical virology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/jmv.1890270213

    authors: Reuman PD,Bernstein DI,Keely SP,Young EC,Sherwood JR,Schiff GM

    更新日期:1989-02-01 00:00:00