Abstract:
:Six patients of primary lymphoma of breast are presented. All our patients were female with median age of 46 years. Combination chemotherapy was the mainstay of treatment in all the patients. Five patients achieved complete remission of which two relapsed, one had a distant relapse and the other was local. Patient with distant relapse expired after a follow-up of 224 months whereas the one with local recurrence was well controlled with radiotherapy only. The role of combination chemotherapy to decrease the distant relapse and thereby mortality is discussed.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Dhabhar BN,Saikia TK,Soman CS,Advani SHkeywords:
subject
Has Abstractpub_date
1992-09-01 00:00:00pages
164-8issue
3eissn
0019-509Xissn
1998-4774journal_volume
29pub_type
杂志文章,评审abstract:INTRODUCTION:Multiple myeloma (MM) is a B-cell malignancy accounting for 0.8% of all cancer deaths globally. This malignancy is characterized by lytic bone disease renal insufficiency, anemia, hypercalcemia, and immunodeficiency. The myeloma cells have enhanced expression of CD138. CD138 is a transmembrane heparin sulf...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_349_17
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:The Ewing sarcoma family of tumors (ESFT) are aggressive malignant tumors with small round cell morphology affecting mainly children and adolescents. The aim of this study is to classify the histological diversity and clinical characteristics of ESFT in children from a Tertiary Care Center in South India. M...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.176700
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Colistin-based combination therapy (CCT) is extensively used to treat infections due to carbapenem-resistant Gram-negative bacteria (CRGNB). There are no data available from India on the usefulness of combination therapy, especially in the oncology setup. The aim of this study was to analyze the clinical eff...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.204767
更新日期:2016-10-01 00:00:00
abstract::Positron emission tomography (PET) has emerged as an important diagnostic tool in the management of lung cancers. Although PET is sensitive in detection of lung cancer, but FDG (2-deoxy-2- 18 fluro-D-glucose) is not tumor specific and may accumulate in a variety of nonmalignant conditions occasionally giving false pos...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509x.44660
更新日期:2008-10-01 00:00:00
abstract::Radiotherapy forms one of the major treatment modalities for head and neck cancers (HNC), and precision radiotherapy techniques, such as intensity-modulated radiotherapy require accurate target delineation to ensure success of the treatment. Conventionally used imaging modalities, such as X-ray computed tomography (CT...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.64717
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Lymphoma combined with hepatitis B infection occupies a relatively higher incidence in China than that of in Europe and America. AIMS:To observe the efficacy and safety of rituximab in combination with chemotherapy in patients with B-cell non-Hodgkin's lymphoma (NHL) and hepatitis B virus (HBV) infection. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.200679
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Chronic myeloid leukemia (CML), is the first malignancy that related to the chromosomal abnormality and include 15-20% of all adulthood leukemia. AIMS:This study aimed to compare the hematologic, breakpoint cluster region-abelson (BCR-ABL) and liver function enzymes changes during treatment period of Imatin...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.176715
更新日期:2015-07-01 00:00:00
abstract:CONTEXT:Tumor budding (TBud) is recognized as a poor prognostic marker in colorectal cancer (CRC) with important treatment implications in Stage II cancers and malignant polyps. There are multiple propositions for bud count reporting but without an uniformly accepted system. The International TBud consensus conference ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_642_17
更新日期:2017-10-01 00:00:00
abstract::Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/ijc.IJC_258_17
更新日期:2017-01-01 00:00:00
abstract::Selective Internal Radiation Therapy is a relatively new technique that irradiates malignant liver lesions using microscopic beads. It provides micro-embolization coupled with high-dose interstitial radiotherapy. Besides colorectal cancers, this therapy has shown benefit in patients with a variety of other tumors incl...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.76625
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Fluorouracil (FU)based chemoradiotherapy is regarded as a standard perioperative treatment in locally advanced rectal cancer. Capecitabine is an oral fluoropyrimidine that generates 5FU preferentially at the tumor site by exploiting the higher activity of the enzyme thymidine phosphorylase in tumor tissue ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/ijc.IJC_174_17
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The Medical Oncology Department at Tata Memorial Hospital, the single largest tertiary cancer care center in Asia, receives in-house registered and referral patient samples from all parts of the country. Our recent studies establish 23% EGFR mutation frequency among Indian population. Here, we extend our stu...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.117023
更新日期:2013-04-01 00:00:00
abstract::Spindle cell haemangioendothelioma (SCH) is a low grade, slowly progressive angiosarcoma of multifocal nature with local recurrences being common. It is histologically marked by cavernous blood spaces and a spindle cell stroma. Its importance lies in recognising its relatively benign nature and differentiating it from...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_545_17
更新日期:2017-12-01 00:00:00
abstract::Gliomatosis peritonei (GP), a rare condition related to ovarian teratomas, is characterized by miliary implants of mature glial tissues on the peritoneum or omentum. We report herein a case of mature teratoma of the ovary with GP with imaging features and pathological correlation. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.17064
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Radiation induced wet desquamation of skin in carcinoma breast patients is a painful condition. In this study topical beclomethasone dipropionate spray was used as prophylaxis with the purpose of reducing risk of the wet desquamation of skin in irradiated field. MATERIALS AND METHODS:Sixty patients...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/0019-509x.29424
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Breast cancer is now the most common cancer in many parts of India and the incidence varies from 12 to 31/100,000, and is rising. Locally advanced breast cancer (LABC) accounts for 30-35% of all cases of breast cancers in India. LABC continues to present a challenge and imposes a major health impact in our c...
journal_title:Indian journal of cancer
pub_type: 临床试验,杂志文章
doi:10.4103/0019-509X.75838
更新日期:2011-01-01 00:00:00
abstract::The utility of computed tomography in pretherapy assessment of esophageal carcinoma is reviewed. Computed tomographic findings in 78 patients with histologically proved esophageal carcinoma were corelated with findings at surgery and histopathology. Computed tomography (CT) was found to be fairly accurate in assessing...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Central nervous system (CNS) metastases are a frequent and severe complication associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC). The first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) have shown considerable efficacy in EGFR-mutated NSCLC. However, the...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/ijc.IJC_455_19
更新日期:2019-11-01 00:00:00
abstract::Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral neuropathy can markedly dete...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_361_18
更新日期:2020-01-01 00:00:00
abstract:PURPOSE OF THE STUDY:To analyze the role of hypofractionated radiotherapy in advanced carcinoma of cervix. BASIC PROCEDURE:Medical records of 62 women with advanced carcinoma cervix III3 treated during 1994-1996 were reviewed. Patients were treated with standard pelvic portals to a total dose of 39Gy in 13 fractions o...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::The clinical microbiology department at CMC&H, Vellore in conjunction with the haematology department carries out routine surveillance of patients admitted to the hematology department. Since 1994 in a sample population of 55 patients with various underlying clinical conditions who have had bone marrow transplant, sep...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:The aim of this prospective study was to evaluate the effects of radiotherapy (RT) on psychiatric disorder in patients undergoing RT for head and neck cancer. MATERIALS AND METHODS:The prospective study included 51 patients with head and neck cancer. The diagnosis of psychiatric disorder was made by Diagnostic...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.180816
更新日期:2016-01-01 00:00:00
abstract::Chylothorax is an uncommon complication in children. Although surgery and trauma are the most common causes encountered, hematological as well as solid malignancies can present with chylothorax. This study aimed to describe the presentation and management of malignant chylothorax in children. This is a case series fro...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_499_17
更新日期:2017-10-01 00:00:00
abstract::L-asparaginase is a valuable chemotherapeutic agent used in the induction of remission and improvement of long term survival in patients with acute lymphoblastic leukemia. Hyperglycemia is a well known side effect of L-asparaginase. Fourteen patients developed hyperglycemia during induction therapy of acute lymphoblas...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the re...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_349_18
更新日期:2018-10-01 00:00:00
abstract:CONTEXT:Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM:To study the cancer profile at Kolar, based on Pathology Depart...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.63011
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Mitochondrial DNA (Mt DNA) defects have been identified in a variety of Tumors, but the exact role of these defects in the pathogenicity and tumor progression is poorly understood. This study aims at identifying the status of mitochondrial OXPHOS genes in neoplastic transformation and attempts to establish a...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.118732
更新日期:2013-07-01 00:00:00
abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_542_18
更新日期:2020-04-01 00:00:00
abstract::Meticulous staging of ovarian cancer has so far been a prerequisite for treatment planning. However, more than 80% of patients operated by non-oncologists all over the world do not under go a complete staging. Recently there have been reports questioning the need for extensive staging from the point of cervical benefi...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00