Abstract:
BACKGROUND:Lymphoma combined with hepatitis B infection occupies a relatively higher incidence in China than that of in Europe and America. AIMS:To observe the efficacy and safety of rituximab in combination with chemotherapy in patients with B-cell non-Hodgkin's lymphoma (NHL) and hepatitis B virus (HBV) infection. METHODS:Ninety-two B-cell lymphoma patients with HBV infection in Sichuan Cancer Hospital from January 2009 to October 2015 were divided into two groups. Patients in Group A (n = 33) were treated with rituximab combined with chemotherapy, while Group B (n = 59) accepted chemotherapy alone. RESULTS:The effective rate (complete response + partial response) was 69.7% in Group A and 44.1% in Group B with significantly statistical difference (P = 0.018). Some of the patients got different grades of hepatic function damage during the period of chemotherapy, but there was no statistically significant difference between these two groups (P = 0.071). CONCLUSIONS:For CD20-positive NHL patients complicated with HBV infection, rituximab combined with chemotherapy modality is effective. The promise efficacy of this regimen could be achieved relying on controllable safety based on antiviral treatment.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Wang S,Zhang Z,Cai H,Wang Ydoi
10.4103/0019-509X.200679subject
Has Abstractpub_date
2016-07-01 00:00:00pages
443-447issue
3eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2016_53_3_443_200679journal_volume
53pub_type
杂志文章abstract:BACKGROUND:Mitochondrial DNA (Mt DNA) defects have been identified in a variety of Tumors, but the exact role of these defects in the pathogenicity and tumor progression is poorly understood. This study aims at identifying the status of mitochondrial OXPHOS genes in neoplastic transformation and attempts to establish a...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.118732
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Breast cancer is now the most common cancer in many parts of India and the incidence varies from 12 to 31/100,000, and is rising. Locally advanced breast cancer (LABC) accounts for 30-35% of all cases of breast cancers in India. LABC continues to present a challenge and imposes a major health impact in our c...
journal_title:Indian journal of cancer
pub_type: 临床试验,杂志文章
doi:10.4103/0019-509X.75838
更新日期:2011-01-01 00:00:00
abstract::Twenty five patients of advanced breast cancer (Stage IIIb and IV) were studied and the histological changes following chemotherapy were looked. All the tumours showed varying degree of histological changes. Twenty eight percent tumours showed Grade I changes, 28 percent had Grade II changes and 28 percent had Grade I...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Seroma formation after mastectomy typically delays recovery and adds to morbidity. AIMS:This retrospective review was undertaken to identify factors which predict development of seroma after mastectomy for breast cancer patients. SETTING AND DESIGN:119 consecutive patients intended for mastectomy for the t...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.38940
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Incidence of rectal cancer has wide geographical variation. Disease pattern in developing countries is different from developed countries as majority of the patients present in advanced stage because of delayed referral and lack of uniform treatment practices. AIMS:Present study describes the patient profil...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::During the last 11 years, 101 patients of Wilms tumor were seen. Of these, 13 patients had metastatic disease at onset while 24 patients presented with relapse at a latter date. Seven patients have been cured, all had favourable histology. The risk factors associated with relapse were found to be unfavourable histolog...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:CONTEXT:The most commonly prescribed conventional fractionation radiotherapy uses 1.8-2.2 Gy per fraction for five fractions in a week. Many times, unwanted interruptions are encountered, which ultimately affect the local control and overall survival. AIMS:The present retrospective study was carried out to study the c...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_517_17
更新日期:2018-04-01 00:00:00
abstract::This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated u...
journal_title:Indian journal of cancer
pub_type: 历史文章,杂志文章
doi:10.4103/ijc.IJC_13_19
更新日期:2019-07-01 00:00:00
abstract::We report a rare case of 'metastatic invasive mole' to the spinal cord causing paraplegia in a 19-year-old woman. There are no such histologically proven reports in the literature since the use of the tumour marker, beta-subunit of human chorionic gonadotrophin (beta-HCG) and chemotherapy. We stress the importance of ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/ijc.IJC_258_17
更新日期:2017-01-01 00:00:00
abstract:CONTEXT:Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM:To study the cancer profile at Kolar, based on Pathology Depart...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.63011
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Ephrin A4 is one of the ephrin ligand molecules belonging to the tyrosine kinases receptor family. It was originally identified in a T-lymphoma cell line and seen to be expressed in human adult tissue as well as several tumor types. In our previous study, we showed the unique pattern of ephrin A4 immunohisto...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.58859
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the outcome of benign vocal cord tumors treated using a laryngeal endoscopy under low temperature-controlled radiofrequency and to elucidate the application of a dynamic laryngoendoscopy in the operation. MATERIALS AND METHODS:85 patients with benign vocal cord tumors were treate...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.151994
更新日期:2015-02-01 00:00:00
abstract::Gliomatosis cerebri is a vary rare neoplastic lesion of the central nervous system. An intra-vitam diagnosis of gliomatosis cerebri can be suggested with a steleolactic biopsy of the lesion in conjunction with Magnetic Resonance Imaging (MRI) findings in the brain. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Increasing incidence of squamous cell carcinoma (SCC) of the oral cavity and oropharynx is reported in young adults. However, there is a paucity regarding etiology and risk factors. AIM:To evaluate the exposure potential carcinogenic factors among a sample aged 45 years and younger, diagnosed with SCC of th...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.197725
更新日期:2016-04-01 00:00:00
abstract::The incidence of late complications for different size of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1 and 52 cases with T2 lesions. Radical radiotherapy was given with three different regimens having dose per fraction as 3.33, 2.5 an...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Human actinomycosis may pose a diagnostic problem at times and is often mistaken for a neoplasm. A thirty-five year old male was clinically diagnosed as a case of carcinoma of the right maxillary sinus on the basis of history, clinical presentation and radiologic findings. Tissue biopsy was negative for malignancy on ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract:: ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_551_18
更新日期:2018-10-01 00:00:00
abstract:Background:Neoadjuvant concurrent chemoradiation (CTRT) is not widely practiced in breast cancers. The current study presents our experience with the use of neoadjuvant CTRT in patients with locally advanced breast cancers (LABC) treated at our center. Methods:The study included all consecutive female patients with in...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_524_19
更新日期:2020-10-01 00:00:00
abstract:Background:Ki-67 index is an important prognostic marker in breast cancer and is also used to differentiate luminal A subtype from luminal B. Inter-observer variations in determining the index and the cut-off value to be considered in distinguishing the two subtypes remain problems in clinical practice. Methods:MIB-1 ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_719_18
更新日期:2020-07-01 00:00:00
abstract::Radiotherapy forms one of the major treatment modalities for head and neck cancers (HNC), and precision radiotherapy techniques, such as intensity-modulated radiotherapy require accurate target delineation to ensure success of the treatment. Conventionally used imaging modalities, such as X-ray computed tomography (CT...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.64717
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Radiation induced wet desquamation of skin in carcinoma breast patients is a painful condition. In this study topical beclomethasone dipropionate spray was used as prophylaxis with the purpose of reducing risk of the wet desquamation of skin in irradiated field. MATERIALS AND METHODS:Sixty patients...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/0019-509x.29424
更新日期:2006-10-01 00:00:00
abstract::We described a 41-year-old patient with acute promyelocytic leukemia (APL) who experienced two successive relapses: one after all-trans retinoic acid (ATRA) treatment and chemotherapy, and another after ATRA treatment and chemotherapy, followed by autologous peripheral blood stem cell transplantation. A third complete...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:The three direct factors that could lead cancer patients to anemia, apart from therapy are iron deficiency, inflammatory cytokines surge and decreased erythropoietin (Epo). Our aim was to quantify biochemical and hematologic markers serum Epo, ferritin (Fe) and tumor necrosis factor-alpha (TNF-α) along with ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.175579
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Sri Lanka became a signatory to the WHO Frame Work Convention on Tobacco Control in September 2003, and this was ratified in November 2003. With a view to reduce the use of tobacco in Sri Lanka, the National Authority on Tobacco and Alcohol Act (NATA) No. 27 of 2006 was implemented. AIM:To assess the beha...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.107753
更新日期:2012-10-01 00:00:00
abstract::The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_343_20
更新日期:2020-04-01 00:00:00
abstract::A case report of a squamous cell carcinoma arising in a dermoid cyst of the ovary in a 29 year old patient is presented. Such an occurrence in young patients is unusual. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract::Cervical cancer is the leading malignancy among Indian women. It has been estimated that in the absence of any control programme, the incident number of cervical cancer cases in the country would rise to 140 thousand by the turn of this century. Cytology screening remains the main stay for the control of cervix cancer...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_542_18
更新日期:2020-04-01 00:00:00
abstract::The use of cell phones is increasing worldwide at a phenomenal pace. While cellular communication has dramatically influenced our lifestyle, its impact on human health has not been completely assessed. Widespread concern continues in the community about the deleterious effects of radiofrequency radiations (with which ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509x.48589
更新日期:2009-01-01 00:00:00