Efficacy and safety analysis of rituximab combined with chemotherapy in the treatment of B-cell lymphoma patients complicated with hepatitis B virus infection.

Abstract:

BACKGROUND:Lymphoma combined with hepatitis B infection occupies a relatively higher incidence in China than that of in Europe and America. AIMS:To observe the efficacy and safety of rituximab in combination with chemotherapy in patients with B-cell non-Hodgkin's lymphoma (NHL) and hepatitis B virus (HBV) infection. METHODS:Ninety-two B-cell lymphoma patients with HBV infection in Sichuan Cancer Hospital from January 2009 to October 2015 were divided into two groups. Patients in Group A (n = 33) were treated with rituximab combined with chemotherapy, while Group B (n = 59) accepted chemotherapy alone. RESULTS:The effective rate (complete response + partial response) was 69.7% in Group A and 44.1% in Group B with significantly statistical difference (P = 0.018). Some of the patients got different grades of hepatic function damage during the period of chemotherapy, but there was no statistically significant difference between these two groups (P = 0.071). CONCLUSIONS:For CD20-positive NHL patients complicated with HBV infection, rituximab combined with chemotherapy modality is effective. The promise efficacy of this regimen could be achieved relying on controllable safety based on antiviral treatment.

journal_name

Indian J Cancer

journal_title

Indian journal of cancer

authors

Wang S,Zhang Z,Cai H,Wang Y

doi

10.4103/0019-509X.200679

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

443-447

issue

3

eissn

0019-509X

issn

1998-4774

pii

IndianJournalofCancer_2016_53_3_443_200679

journal_volume

53

pub_type

杂志文章
  • Mitochondria and tumors: a new perspective.

    abstract:BACKGROUND:Mitochondrial DNA (Mt DNA) defects have been identified in a variety of Tumors, but the exact role of these defects in the pathogenicity and tumor progression is poorly understood. This study aims at identifying the status of mitochondrial OXPHOS genes in neoplastic transformation and attempts to establish a...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.118732

    authors: Chintha R,Kaipa PR,Sekhar N,Hasan Q

    更新日期:2013-07-01 00:00:00

  • Outcome of combined modality treatment including neoadjuvant chemotherapy of 128 cases of locally advanced breast cancer: data from a tertiary cancer center in northern India.

    abstract:BACKGROUND:Breast cancer is now the most common cancer in many parts of India and the incidence varies from 12 to 31/100,000, and is rising. Locally advanced breast cancer (LABC) accounts for 30-35% of all cases of breast cancers in India. LABC continues to present a challenge and imposes a major health impact in our c...

    journal_title:Indian journal of cancer

    pub_type: 临床试验,杂志文章

    doi:10.4103/0019-509X.75838

    authors: Raina V,Kunjahari M,Shukla NK,Deo SV,Sharma A,Mohanti BK,Sharma DN

    更新日期:2011-01-01 00:00:00

  • Histopathological changes following anterior chemotherapy in advanced breast cancer.

    abstract::Twenty five patients of advanced breast cancer (Stage IIIb and IV) were studied and the histological changes following chemotherapy were looked. All the tumours showed varying degree of histological changes. Twenty eight percent tumours showed Grade I changes, 28 percent had Grade II changes and 28 percent had Grade I...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Khanna AK,Saxena SK,Khanna S,Kumar A

    更新日期:1990-06-01 00:00:00

  • Factors predicting seroma formation after mastectomy for Chinese breast cancer patients.

    abstract:BACKGROUND:Seroma formation after mastectomy typically delays recovery and adds to morbidity. AIMS:This retrospective review was undertaken to identify factors which predict development of seroma after mastectomy for breast cancer patients. SETTING AND DESIGN:119 consecutive patients intended for mastectomy for the t...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509x.38940

    authors: Loo WT,Chow LW

    更新日期:2007-07-01 00:00:00

  • Patient profile and treatment outcome of rectal cancer patients treated with multimodality therapy at a regional cancer center.

    abstract:BACKGROUND:Incidence of rectal cancer has wide geographical variation. Disease pattern in developing countries is different from developed countries as majority of the patients present in advanced stage because of delayed referral and lack of uniform treatment practices. AIMS:Present study describes the patient profil...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Deo S,Kumar S,Shukla NK,Kar M,Mohanti BK,Sharma A,Raina V,Rath GK

    更新日期:2004-07-01 00:00:00

  • Management of metastatic Wilms tumor: an eleven year experience.

    abstract::During the last 11 years, 101 patients of Wilms tumor were seen. Of these, 13 patients had metastatic disease at onset while 24 patients presented with relapse at a latter date. Seven patients have been cured, all had favourable histology. The risk factors associated with relapse were found to be unfavourable histolog...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Misra D,Gupta DK,Mitra DK,Bhatnagar V,Bajpai M,Mathur M,Rohatgi M

    更新日期:1996-03-01 00:00:00

  • Compliance to radiotherapy: A tertiary care center experience.

    abstract:CONTEXT:The most commonly prescribed conventional fractionation radiotherapy uses 1.8-2.2 Gy per fraction for five fractions in a week. Many times, unwanted interruptions are encountered, which ultimately affect the local control and overall survival. AIMS:The present retrospective study was carried out to study the c...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_517_17

    authors: Gupta S,Rastogi K,Bhatnagar AR,Singh D,Gupta K,Choudhary AS

    更新日期:2018-04-01 00:00:00

  • The founding of the Tata Memorial Hospital, 1932-1941.

    abstract::This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated u...

    journal_title:Indian journal of cancer

    pub_type: 历史文章,杂志文章

    doi:10.4103/ijc.IJC_13_19

    authors: Kavadi SN

    更新日期:2019-07-01 00:00:00

  • 'Metastatic invasive mole' causing paraplegia.

    abstract::We report a rare case of 'metastatic invasive mole' to the spinal cord causing paraplegia in a 19-year-old woman. There are no such histologically proven reports in the literature since the use of the tumour marker, beta-subunit of human chorionic gonadotrophin (beta-HCG) and chemotherapy. We stress the importance of ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Jayaprakash PG,Ajithkumar TV,Amma NS,Nair MK

    更新日期:1999-06-01 00:00:00

  • Targeted therapy in nonsmall cell lung cancer.

    abstract::Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/ijc.IJC_258_17

    authors: Puri T

    更新日期:2017-01-01 00:00:00

  • Cancer profile in the Department of Pathology of Sri Devaraj Urs Medical College, Kolar: a ten years study.

    abstract:CONTEXT:Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM:To study the cancer profile at Kolar, based on Pathology Depart...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.63011

    authors: Kalyani R,Das S,Bindra Singh MS,Kumar H

    更新日期:2010-04-01 00:00:00

  • Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome.

    abstract:BACKGROUND:Ephrin A4 is one of the ephrin ligand molecules belonging to the tyrosine kinases receptor family. It was originally identified in a T-lymphoma cell line and seen to be expressed in human adult tissue as well as several tumor types. In our previous study, we showed the unique pattern of ephrin A4 immunohisto...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.58859

    authors: Abdou AG,Abd el-Wahed MM,Asaad NY,Samaka RM,Abdallaha R

    更新日期:2010-01-01 00:00:00

  • Outcome analysis of benign vocal cord tumors treated by laryngeal endoscopy under low temperature-controlled radiofrequency.

    abstract:OBJECTIVE:This study aimed to evaluate the outcome of benign vocal cord tumors treated using a laryngeal endoscopy under low temperature-controlled radiofrequency and to elucidate the application of a dynamic laryngoendoscopy in the operation. MATERIALS AND METHODS:85 patients with benign vocal cord tumors were treate...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.151994

    authors: Wang ZY,Xu L,Wu KM,Zhang Y,Chen W

    更新日期:2015-02-01 00:00:00

  • Gliomatosis cerebri--a case report.

    abstract::Gliomatosis cerebri is a vary rare neoplastic lesion of the central nervous system. An intra-vitam diagnosis of gliomatosis cerebri can be suggested with a steleolactic biopsy of the lesion in conjunction with Magnetic Resonance Imaging (MRI) findings in the brain. ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Radhakrishnan VV,Misra BK,Rout D

    更新日期:1996-09-01 00:00:00

  • Squamous cell carcinoma of the oral cavity and oropharynx in patients aged 18-45 years: A case-control study to evaluate the risk factors with emphasis on stress, diet, oral hygiene, and family history.

    abstract:BACKGROUND:Increasing incidence of squamous cell carcinoma (SCC) of the oral cavity and oropharynx is reported in young adults. However, there is a paucity regarding etiology and risk factors. AIM:To evaluate the exposure potential carcinogenic factors among a sample aged 45 years and younger, diagnosed with SCC of th...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.197725

    authors: Dholam KP,Chouksey GC

    更新日期:2016-04-01 00:00:00

  • Late radiation induced laryngeal oedema in the treatment of vocal cord cancer: analysis using the linear quadratic model.

    abstract::The incidence of late complications for different size of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1 and 52 cases with T2 lesions. Radical radiotherapy was given with three different regimens having dose per fraction as 3.33, 2.5 an...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Deore SM,Supe SJ,Sharma V,Dinshaw KA

    更新日期:1993-09-01 00:00:00

  • Actinomycosis mimicking carcinoma of the maxillary sinus.

    abstract::Human actinomycosis may pose a diagnostic problem at times and is often mistaken for a neoplasm. A thirty-five year old male was clinically diagnosed as a case of carcinoma of the right maxillary sinus on the basis of history, clinical presentation and radiologic findings. Tissue biopsy was negative for malignancy on ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Pradhan S,Datta NR,Prasad KN,Ayyagari S,Pandey R

    更新日期:1993-03-01 00:00:00

  • Harmonic scalpel versus conventional diathermy: Is one really better than the other?

    abstract:: ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_551_18

    authors: Suhani.

    更新日期:2018-10-01 00:00:00

  • Study of pathological complete response rate with neoadjuvant concurrent chemoradiation with paclitaxel in locally advanced breast cancer.

    abstract:Background:Neoadjuvant concurrent chemoradiation (CTRT) is not widely practiced in breast cancers. The current study presents our experience with the use of neoadjuvant CTRT in patients with locally advanced breast cancers (LABC) treated at our center. Methods:The study included all consecutive female patients with in...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_524_19

    authors: Iyer P,Radhakrishnan V,Balasubramanian A,Sridevi V,Krishnamurthy A,Dhanushkodi M,Sundersingh S,Ganesarajah S

    更新日期:2020-10-01 00:00:00

  • Study of Ki-67 index in the molecular subtypes of breast cancer: Inter-observer variability and automated scoring.

    abstract:Background:Ki-67 index is an important prognostic marker in breast cancer and is also used to differentiate luminal A subtype from luminal B. Inter-observer variations in determining the index and the cut-off value to be considered in distinguishing the two subtypes remain problems in clinical practice. Methods:MIB-1 ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_719_18

    authors: Meermira D,Swain M,Gowrishankar S

    更新日期:2020-07-01 00:00:00

  • Challenges in integrating 18FDG PET-CT into radiotherapy planning of head and neck cancer.

    abstract::Radiotherapy forms one of the major treatment modalities for head and neck cancers (HNC), and precision radiotherapy techniques, such as intensity-modulated radiotherapy require accurate target delineation to ensure success of the treatment. Conventionally used imaging modalities, such as X-ray computed tomography (CT...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/0019-509X.64717

    authors: Dandekar P,Partridge M,Kazi R,Nutting C,Harrington K,Newbold K

    更新日期:2010-07-01 00:00:00

  • Prophylactic beclomethasone spray to the skin during postoperative radiotherapy of carcinoma breast: a prospective randomized study.

    abstract:BACKGROUND AND AIMS:Radiation induced wet desquamation of skin in carcinoma breast patients is a painful condition. In this study topical beclomethasone dipropionate spray was used as prophylaxis with the purpose of reducing risk of the wet desquamation of skin in irradiated field. MATERIALS AND METHODS:Sixty patients...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.4103/0019-509x.29424

    authors: Shukla PN,Gairola M,Mohanti BK,Rath GK

    更新日期:2006-10-01 00:00:00

  • Early relapse after non myeloablative allogeneic stem cell transplantation in a patient with acute promyelocytic leukemia in complete molecular remission.

    abstract::We described a 41-year-old patient with acute promyelocytic leukemia (APL) who experienced two successive relapses: one after all-trans retinoic acid (ATRA) treatment and chemotherapy, and another after ATRA treatment and chemotherapy, followed by autologous peripheral blood stem cell transplantation. A third complete...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Tavernier E,Thomas X

    更新日期:2003-10-01 00:00:00

  • A study on biochemical facet of anemia in cancers: A strong link between erythropoietin and tumor necrosis factor alpha in anemic cancer patients.

    abstract:BACKGROUND:The three direct factors that could lead cancer patients to anemia, apart from therapy are iron deficiency, inflammatory cytokines surge and decreased erythropoietin (Epo). Our aim was to quantify biochemical and hematologic markers serum Epo, ferritin (Fe) and tumor necrosis factor-alpha (TNF-α) along with ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.175579

    authors: Kalyani P,Jamil K

    更新日期:2015-01-01 00:00:00

  • An assessment of the effectiveness of tobacco control measures on behavior changes related to tobacco use among adolescents and young adults in a district in Sri Lanka.

    abstract:INTRODUCTION:Sri Lanka became a signatory to the WHO Frame Work Convention on Tobacco Control in September 2003, and this was ratified in November 2003. With a view to reduce the use of tobacco in Sri Lanka, the National Authority on Tobacco and Alcohol Act (NATA) No. 27 of 2006 was implemented. AIM:To assess the beha...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.107753

    authors: De Silva WD,Sinha DN,Kahandawaliyanag A

    更新日期:2012-10-01 00:00:00

  • Time, distance, shielding and ALARA; drawing similarities between measures for radiation protection and Coronavirus disease pandemic response.

    abstract::The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_343_20

    authors: Mukherji A,Gupta T,Agarwal JP

    更新日期:2020-04-01 00:00:00

  • Primary squamous cell carcinoma of the ovary in a young patient. A case report.

    abstract::A case report of a squamous cell carcinoma arising in a dermoid cyst of the ovary in a 29 year old patient is presented. Such an occurrence in young patients is unusual. ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Sahasrabudhe NS,Nayak S,Vaidya VS,Deshmukh SD,Shrotri AN

    更新日期:2002-06-01 00:00:00

  • Screening for cancer of uterine cervix and approaches adopted in India.

    abstract::Cervical cancer is the leading malignancy among Indian women. It has been estimated that in the absence of any control programme, the incident number of cervical cancer cases in the country would rise to 140 thousand by the turn of this century. Cytology screening remains the main stay for the control of cervix cancer...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Murthy NS,Mathew A

    更新日期:1999-06-01 00:00:00

  • High potential of SOX21 gene promoter methylation as an epigenetic biomarker for early detection of colorectal cancer.

    abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_542_18

    authors: Moradi K,Babaei E,Rezvani N,Safaralizadeh R,Bashiri H,Feizi MAH

    更新日期:2020-04-01 00:00:00

  • Cell phones and tumor: still in no man's land.

    abstract::The use of cell phones is increasing worldwide at a phenomenal pace. While cellular communication has dramatically influenced our lifestyle, its impact on human health has not been completely assessed. Widespread concern continues in the community about the deleterious effects of radiofrequency radiations (with which ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/0019-509x.48589

    authors: Kohli DR,Sachdev A,Vats HS

    更新日期:2009-01-01 00:00:00