abstract：Background:Undernutrition is a common childhood problem in India which may contribute to higher risk of infection and lower survival rate in children with acute lymphoblastic leukemia (ALL). Methods:In our study, we retrospectively included patients of age group 1-15 years who were treated for ALL and survived inducti...

journal_title：Indian journal of cancer

authors： Sonowal R,Gupta V

更新日期：2021-01-06 00:00:00

abstract：Background:Gestational trophoblastic neoplasia (GTN) are a spectrum of tumors that develop from placental tissue. We aimed to evaluate the management and treatment outcome of GTN. Methods:Patients diagnosed with GTN presented to Kasr Alainy Center of Clinical Oncology between 2008 and 2017 were included in this study....

journal_title：Indian journal of cancer

authors： Edesa WA,Ayad NN,Mounir AM,Haggag MH

更新日期：2021-01-06 00:00:00

abstract：Background:Programmed death-ligand 1 (PD-L1) has been determined as a reliable prognostic factor for various malignancies. In this study, we aimed to determine the prognostic effect of PD-L1 expression in tumor-infiltrating immune cells (TIICs) of nasopharyngeal carcinoma (NPC) patients. Methods:Seventy patients diagn...

journal_title：Indian journal of cancer

authors： Sahinli H,Akyürek N,Yılmaz M,Kandemir O,Duran AO,Kulaçoğlu S,Uçar G,Acar E,Özet A,Gümüş M,Ç Öksüzoğlu ÖB,Özdemir NY

更新日期：2020-12-10 00:00:00

abstract：Background:Mutations in ROS1, ALK, and MET genes are targetable alterations in non-small cell lung cancer (NSCLC). They can be evaluated by different techniques, most commonly fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC). Methods:We explored the prevalence of ROS1, ALK, MET mutations, discu...

journal_title：Indian journal of cancer

authors： Singh A,Kumar R,Shetty O,Desai S,Rane S

更新日期：2020-11-24 00:00:00

abstract：Background:Neoadjuvant concurrent chemoradiation (CTRT) is not widely practiced in breast cancers. The current study presents our experience with the use of neoadjuvant CTRT in patients with locally advanced breast cancers (LABC) treated at our center. Methods:The study included all consecutive female patients with in...

journal_title：Indian journal of cancer

authors： Iyer P,Radhakrishnan V,Balasubramanian A,Sridevi V,Krishnamurthy A,Dhanushkodi M,Sundersingh S,Ganesarajah S

更新日期：2020-10-01 00:00:00

abstract：Background:Ki-67 index is an important prognostic marker in breast cancer and is also used to differentiate luminal A subtype from luminal B. Inter-observer variations in determining the index and the cut-off value to be considered in distinguishing the two subtypes remain problems in clinical practice. Methods:MIB-1 ...

journal_title：Indian journal of cancer

authors： Meermira D,Swain M,Gowrishankar S

更新日期：2020-07-01 00:00:00

abstract：Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...

journal_title：Indian journal of cancer

authors： Moradi K,Babaei E,Rezvani N,Safaralizadeh R,Bashiri H,Feizi MAH

更新日期：2020-04-01 00:00:00

abstract：:The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...

journal_title：Indian journal of cancer

authors： Mukherji A,Gupta T,Agarwal JP

更新日期：2020-04-01 00:00:00

abstract：:Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral neuropathy can markedly dete...

journal_title：Indian journal of cancer

authors： Ahuja D,Bharati SJ,Gupta N,Kumar V,Bhatnagar S

更新日期：2020-01-01 00:00:00

abstract：:Central nervous system (CNS) metastases are a frequent and severe complication associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC). The first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) have shown considerable efficacy in EGFR-mutated NSCLC. However, the...

journal_title：Indian journal of cancer

authors： Shetty V,Babu S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-known adverse effect of vincristine (VCR). Literature suggests that Asians are predisposed to develop SIADH following VCR administration. However, data regarding the occurrence of SIADH in children with malignancy are limited. This st...

journal_title：Indian journal of cancer

authors： Seetharam S,Thankamony P,Gopakumar KG,Krishna KMJ

更新日期：2019-10-01 00:00:00

abstract：:This note presents a brief account of the ideas and efforts of V.R. Khanolkar in the period 1952-1962 to develop the Indian Cancer Research Centre into a "center of excellence". Khanolkar, who is recognized as a pioneer in cancer research in India, focused on developing multidisciplinary medical research and mentored ...

journal_title：Indian journal of cancer

authors： Kavadi SN

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Wilms' tumor 1 (WT1) mutation has recently been detected in gliomas. Growing data indicate that WT1 mutation plays a causal role in gliomagenesis and is overexpressed in most glioblastomas. An emerging immunotherapy targeting WT1 has shown to be effective in resistant glioblastomas in clinical trials. WT1 ex...

journal_title：Indian journal of cancer

authors： Manocha A,Jain S

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Non-urothelial bladder tumors (NUBTs) are uncommon accounting for approximately 10% of the total urinary bladder tumors while 90% are urothelial in origin. There are very limited comprehensive studies on NUBTs. AIMS AND OBJECTIVES:The objectives of the study were to analyze the clinicopathological and immun...

journal_title：Indian journal of cancer

authors： Kaur S,Gupta A,Gulwani HV

更新日期：2019-07-01 00:00:00

abstract：:This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated u...

journal_title：Indian journal of cancer

authors： Kavadi SN

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Metaplastic breast carcinoma (MBC) is a rare disease with incidence of less than 1%. MBC present with a larger tumor size, less number of nodes involved, mostly undifferentiated triple negative tumors. We aimed to determine progression-free and overall survival and reported hospital-based incidence of MBC. ...

journal_title：Indian journal of cancer

authors： Samoon Z,Beg M,Idress R,Jabbar AA

更新日期：2019-04-01 00:00:00

abstract：:Rat sarcoma viral oncogene homolog (RAS) and B-Raf murine sarcoma viral oncogene homolog B1 (BRAF) are members of the same signaling pathway (RAS-RAF-mitogen-activated protein kinase (MAPK) in colorectal cancer (CRC). It is generally assumed that BRAF mutations are seen only with wild-type RAS in CRC. But RAS and BRAF...

journal_title：Indian journal of cancer

authors： Ates O,Yalcin S

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Second primary malignancy (SPM) is associated with decreased overall survival (OS) in laryngeal carcinomas (LC). METHODS:One hundred eighty three LC patients were analyzed retrospectively. The primary and secondary endpoints were the incidence of SPM and the OS difference between patients with and without...

journal_title：Indian journal of cancer

authors： Ozdemir Y,Topkan E

更新日期：2019-01-01 00:00:00

abstract：:Adjuvant treatment in gastric adenocarcinoma has been a challenge for the treating specialists, and despite several trials, a clear consensus is yet to be defined. The higher propensity for lymph nodal involvement and locoregional recurrences led to the hypothesis that locoregional and systemic treatments need to be e...

journal_title：Indian journal of cancer

authors： Chelakkot PG,Ravind R,Sruthi K,Menon D

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Indian journal of cancer

authors： Suhani.

更新日期：2018-10-01 00:00:00

abstract：:A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the re...

journal_title：Indian journal of cancer

authors： Pandey AS,Shrestha S

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:This study was undertaken to evaluate the clinicopathological characteristics of patients with breast cancer at our institute, a tertiary-care cancer center in northern India. MATERIALS AND METHODS:This retrospective study included all patients with breast cancer registered at our institute from January 1...

journal_title：Indian journal of cancer

authors： Gogia A,Deo SV,Shukla NK,Mathur S,Sharma DN,Tiwari A

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Recently published prospective clinical trials and two meta-analyses have shown that addition of induction chemotherapy (IC) to concurrent chemoradiation (CRT) could potentially improve outcomes in comparison to CRT alone, in locoregionally advanced nasopharyngeal carcinoma (LANPC). Although it remains uncle...

journal_title：Indian journal of cancer

authors： Lokesh KN,Chaudhuri T,Lakshmaiah KC,Babu KG,Lokanatha D,Jacob LA,Suresh Babu MC,Rudresha AH,Rajeev LK

更新日期：2018-07-01 00:00:00

abstract：:Invasive fungal infections constitute a major cause of morbidity and mortality in children undergoing therapy for hematological malignancies. We report a 1-year-old boy who was receiving chemotherapy for acute lymphoblastic leukemia. His clinical course was complicated by a clinical syndrome consistent with neutropeni...

journal_title：Indian journal of cancer

authors： Totadri S,Sundersingh S,Natarajan R,Seshadri RA,Radhakrishnan V

更新日期：2018-07-01 00:00:00

abstract：CONTEXT:The most commonly prescribed conventional fractionation radiotherapy uses 1.8-2.2 Gy per fraction for five fractions in a week. Many times, unwanted interruptions are encountered, which ultimately affect the local control and overall survival. AIMS:The present retrospective study was carried out to study the c...

journal_title：Indian journal of cancer

authors： Gupta S,Rastogi K,Bhatnagar AR,Singh D,Gupta K,Choudhary AS

更新日期：2018-04-01 00:00:00

abstract：Background and Objectives:Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at ...

journal_title：Indian journal of cancer

authors： Thiagarajan S,Fathehi K,Nair D,Deshmukh A,Pantvaidya G,Chaukar DA,D'Cruz AK

更新日期：2018-01-01 00:00:00

abstract：Background:Low- and middle-income countries require to specify early detection programs and intervention models for breast cancer. The aim of this study was to assess the performance efficacy of an Iraqi early detection model in terms of cancer detection rate (CDR) and the method of participation in this program. Mate...

journal_title：Indian journal of cancer

authors： Shakor JK,Mohammed AK

更新日期：2018-01-01 00:00:00

abstract：:Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...

journal_title：Indian journal of cancer

authors： Mistry R,Patil A

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Tumor budding (TBud) is recognized as a poor prognostic marker in colorectal cancer (CRC) with important treatment implications in Stage II cancers and malignant polyps. There are multiple propositions for bud count reporting but without an uniformly accepted system. The International TBud consensus conference ...

journal_title：Indian journal of cancer

authors： Roy P,Datta J,Roy M,Mallick I,Mohandas M

更新日期：2017-10-01 00:00:00

abstract：:Chylothorax is an uncommon complication in children. Although surgery and trauma are the most common causes encountered, hematological as well as solid malignancies can present with chylothorax. This study aimed to describe the presentation and management of malignant chylothorax in children. This is a case series fro...

journal_title：Indian journal of cancer

authors： Totadri S,Trehan A,Bhattacharya A,Bansal D,Attri SV,Srinivasan R

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:We aimed to study the compliance and treatment outcome of patients who received adjuvant treatment following curative resection for periampullary cancers periampullary cancers. MATERIALS AND METHODS:Institute medical records of PAC treated during 2007-2014 were retrieved. Demographics, treatment, and outcom...

journal_title：Indian journal of cancer

authors： Pathy S,Mallick S,Sharma A,Shukla NK,Sahni P,Pal S,S Deo SV,Mohanti BK,Upadhyay AD

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:Multiple myeloma (MM) is a B-cell malignancy accounting for 0.8% of all cancer deaths globally. This malignancy is characterized by lytic bone disease renal insufficiency, anemia, hypercalcemia, and immunodeficiency. The myeloma cells have enhanced expression of CD138. CD138 is a transmembrane heparin sulf...

journal_title：Indian journal of cancer

authors： Nageshwari B,Merugu R

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The utilization and extent of pelvic lymph node dissection (PLND) varies depending on the disease and practice patterns. AIMS:This study compares practice patterns in utilization of PLND between Indian and United States (US) practices. SETTINGS AND DESIGN:We focused on 415 patients (204 India; 211 US) pros...

journal_title：Indian journal of cancer

authors： Abdollah F,Arora S,Jindal T,Gild P,Sood A,Yuvaraja TB,Ahlawat RK,Gupta NP,Bhandari M,Menon M

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:: Indian families are known for adopting the role of caregiver naturally when someone in the family falls ill to cancer. Although there were strong family structure and system existed here, now the changing family pattern and structure are challenging the role of cancer caregiving as well. OBJECTIVE:: Thi...

journal_title：Indian journal of cancer

authors： Sivakumar C

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Patients of head and neck malignancies often develop oral mucositis and invite various pathogens to colonize over it. OBJECTIVES:The objective of this study is to identify the fungi isolated from patients undergoing radiotherapy (RT) for head and neck cancer, to determine the antifungal susceptibility of th...

journal_title：Indian journal of cancer

authors： Raj S,Sharma D,Mate P,Capoor MR,Bhowmik KT

更新日期：2017-01-01 00:00:00

abstract：:Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...

journal_title：Indian journal of cancer

authors： Puri T

更新日期：2017-01-01 00:00:00

abstract：AIMS:Volumetric modulated arc radiotherapy (VMAT) is used for inoperable, locally advanced nonsmall cell lung cancer, where three-dimensional conformal radiotherapy (3D-CRT) cannot yield an acceptable plan. METHODS:The planning and treatment data were prospectively collected on the first 18 patients treated using VMAT...

journal_title：Indian journal of cancer

authors： Shrimali RK,Arunsingh M,Reddy GD,Mandal S,Arun B,Prasath S,Sinha S,Mallick I,Achari R,Chatterjee S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:There is limited Indian data on clinical profile and treatment outcomes for patients with Stage IV adenocarcinoma of lung. AIM:We aimed to prospectively study the clinical profile and treatment outcomes for patients with Stage IV adenocarcinoma of lung at a tertiary cancer center. MATERIALS AND METHODS:One...

journal_title：Indian journal of cancer

authors： Paliwal P,Rajappa S,Santa A,Mohan M,Murthy S,Lavanya N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Plumbagin (5-hydroxy-2-methyl-1,4-napthoquinone) derived from Plumbago species is a potential anti-tumour agent. Plumbagin has been tested for anti-cancer activity in vitro and in vivo using mice model. AIM:To study the tumour suppressing efficacy of plumbagin using zebrafish model. MATERIALS AND METHODS:H...

journal_title：Indian journal of cancer

authors： Vinothkumar R,Ceasar SA,Divyarupa A

更新日期：2017-01-01 00:00:00

abstract：CONTEXT:Regional epidemiological data regarding the epidermal growth factor receptor (EGFR) mutation status in non-small-cell lung cancers (NSCLC) is an unmet need from the eastern part of India. AIMS:To report the incidence of EGFR mutation and its correlation with the phenotypical characteristics, in NSCLC patients ...

journal_title：Indian journal of cancer

authors： Chatterjee K,Ray A,Chattopadhyay B

更新日期：2017-01-01 00:00:00