Selective internal radiation therapy: 90Y (yttrium) labeled microspheres for liver malignancies (primary and metastatic).

Abstract:

:Selective Internal Radiation Therapy is a relatively new technique that irradiates malignant liver lesions using microscopic beads. It provides micro-embolization coupled with high-dose interstitial radiotherapy. Besides colorectal cancers, this therapy has shown benefit in patients with a variety of other tumors including carcinoid tumors, lung, breast, sarcoma, colon, hepatocellular and ocular melanoma. Its clinical benefit can be as much as 85%, survival can be doubled and patients with extensive colorectal metastases not amenable to resection or ablation can be offered a 32% chance of surviving for 18 months. Ongoing and future studies will refine our understanding of optimizing patient eligibility, dosage, frequency as well as novel applications.

journal_name

Indian J Cancer

journal_title

Indian journal of cancer

authors

Uthappa MC,Ravikumar R,Gupta A

doi

10.4103/0019-509X.76625

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

18-23

issue

1

eissn

0019-509X

issn

1998-4774

pii

IndianJournalofCancer_2011_48_1_18_76625

journal_volume

48

pub_type

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