Abstract:
INTRODUCTION:Despite lower incidence of breast cancer in India, the total number of cases and the net mortality is high. To reduce this increasing load of mortality due to breast cancer we need to lay emphasis on early detection and increased use of systemic therapy. Early detection itself depends on early presentation to a health facility; thus, it is important to identify factors affecting delay in a presentation to hospital. AIM AND OBJECTIVES:To study the clinico-social profile of breast carcinoma patients attending a tertiary care hospital and to study the time lag since detection of lump by women and presentation to the hospital and factors affecting them. MATERIALS AND METHODS:A total of 120 primary breast cancer patients visiting a tertiary care hospital over a period of 7 months (August 2010 to February 2011) were taken up for study. A detailed retrospective analysis of patients was done according to planned proforma. OBSERVATIONS:Maximum study subjects were in the age group of 41-50 years. Right and left breasts were equally affected. The most common histo-pathological type of breast carcinoma observed was invasive ductal carcinoma (NOS) in 105 (87.50%) cases. Majority of the cases were in stage III or stage II. The median time lag self-detection of lump in the breast by women and presentation to the hospital was 6 months. Women living in a rural area, those with lower socio-economic status and those with older age tend to assess health-care late. CONCLUSIONS:Carcinoma of the breast is a common cancer affecting young to middle age group with invasive ductal carcinoma being the most common histological type. Delay in presentation and late stage presentation is a major concern. Hence, proper awareness and screening programmers are needed to identify, inform and educate these categories of women.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Thakur NA,Humne AY,Godale LBdoi
10.4103/0019-509X.175602subject
Has Abstractpub_date
2015-01-01 00:00:00pages
102-5issue
1eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2015_52_1_102_175602journal_volume
52pub_type
杂志文章abstract:CONTEXT:The most commonly prescribed conventional fractionation radiotherapy uses 1.8-2.2 Gy per fraction for five fractions in a week. Many times, unwanted interruptions are encountered, which ultimately affect the local control and overall survival. AIMS:The present retrospective study was carried out to study the c...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_517_17
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Globally tobacco epidemic kills nearly six million people annually. Consumption of tobacco products is on the rise in low- and middle-income countries. Tobacco is addictive; hence, tobacco users need support in quitting. AIMS:Providing tobacco cessation services to women in community enabling them to quit t...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.147474
更新日期:2014-12-01 00:00:00
abstract::During the last 11 years, 101 patients of Wilms tumor were seen. Of these, 13 patients had metastatic disease at onset while 24 patients presented with relapse at a latter date. Seven patients have been cured, all had favourable histology. The risk factors associated with relapse were found to be unfavourable histolog...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:Proteomics is increasingly employed in both neurological and oncological research, and applied widely in every area of neuroscience research including brain cancer. Astrocytomas are the most common glioma and can occur in most parts of the brain and occasionally in the spinal cord. Patients with high-grade...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.138271
更新日期:2014-04-01 00:00:00
abstract::Alpha-fetoprotein secreting (AFP) Sertoli-Leydig cell tumors of ovary (SLCT) are now identified as a distinct entity among the uncommon group of sex cord tumors of ovary. We report an unusual case of recurrent AFP secreting ovarian tumors and as ileocecal mesenteric cyst in a 25-year-old patient resulting in difficult...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.48599
更新日期:2009-01-01 00:00:00
abstract:CONTEXT:Malnutrition is prevalent in children with cancer at diagnosis, especially in low- and middle-income countries (LMIC) where the great majority of children live. It is associated with an added burden of morbidity and mortality. AIMS:Answers were sought to the best measure of nutritional status in LMIC, the impa...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.175827
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:The Ewing sarcoma family of tumors (ESFT) are aggressive malignant tumors with small round cell morphology affecting mainly children and adolescents. The aim of this study is to classify the histological diversity and clinical characteristics of ESFT in children from a Tertiary Care Center in South India. M...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.176700
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:The aim was to evaluate the safety, feasibility and efficacy of computed tomography (CT)-guided percutaneous interstitial brachytherapy using radioactive iodine-125 ( 125 I) seeds for the treatment of lung cancer. MATERIALS AND METHODS:Included in this study were 45 male and 35 female patients aged 52-85 years...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.151999
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Plasma cell leukemia (PCL) is a rare aggressive variant of multiple myeloma (MM) characterized by a fulminant course and poor prognosis. Flow cytometry (FCM) is very useful in the diagnosis of the plasma cell leukemia. Herein, we present 10 cases of PCL. MATERIALS AND METHODS:We retrospectively studied immu...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.134605
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Patients of head and neck malignancies often develop oral mucositis and invite various pathogens to colonize over it. OBJECTIVES:The objective of this study is to identify the fungi isolated from patients undergoing radiotherapy (RT) for head and neck cancer, to determine the antifungal susceptibility of th...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_155_17
更新日期:2017-01-01 00:00:00
abstract::Neuroendocrine tumors, including carcinoids account for less than 1% of gastric tumors. Various subtypes of gastric carcinoids have been reported earlier. The present case deals with two unusual presentations, diagnosis and course of a gastric neuroendocrine tumor in an adult patient. A 35-years-old male initially pre...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.16700
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to evaluate the efficacy and safety of pemetrexed chemotherapy combined with intrapleural injection of pemetrexed and bevacizumab in the treatment of malignant pleural mesothelioma (MPM)-mediated malignant pleural effusion, and analyze the objective response rate (ORR), the me...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.154058
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:Phyllodes tumor (PT) is a rare fibroepithelial neoplasm comprising <1% of all breast tumors. Clinical spectrum ranges from benign (B), borderline (BL), and locally recurrent to malignant (M) and metastatic type. The aim of our study was to analyze the clinicopathological factors, compare treatment options, and ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.176698
更新日期:2015-07-01 00:00:00
abstract::A rare morphological variant of acute lymphoblastic leukaemia in a ten years old child is described. Ninety five percent of the lymphoblasts had significant number of course granules in the cytoplasm. Diagnostic and prognostic significance of this variant is discussed. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:CONTEXT:Regional epidemiological data regarding the epidermal growth factor receptor (EGFR) mutation status in non-small-cell lung cancers (NSCLC) is an unmet need from the eastern part of India. AIMS:To report the incidence of EGFR mutation and its correlation with the phenotypical characteristics, in NSCLC patients ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_239_17
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Plumbagin (5-hydroxy-2-methyl-1,4-napthoquinone) derived from Plumbago species is a potential anti-tumour agent. Plumbagin has been tested for anti-cancer activity in vitro and in vivo using mice model. AIM:To study the tumour suppressing efficacy of plumbagin using zebrafish model. MATERIALS AND METHODS:H...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.219580
更新日期:2017-01-01 00:00:00
abstract::The office of the Drugs Controller General (India) vide order dated 19 th November 2013 has made audio visual (AV) recording of the informed consent mandatory for the conduct of all clinical trials in India. We therefore developed a standard operating procedure (SOP) to ensure that this is performed in compliance with...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.138158
更新日期:2014-04-01 00:00:00
abstract::In the cervical cancer cases registered at the Cancer Hospital at Barshi, India during 1988-90, 99 of the 105 cases were clinically staged (Total number of cases registered: 136). The annual number of cases were too few for a comparison of stage distribution between the registry years. However, comparison of the propo...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:AIMS:The aim of this study is to investigate the activity and toxicity of etoposide with AUC 6 doses of carboplatin in patients with previously untreated extensive disease - small-cell lung cancer (SCLC). MATERIALS AND METHODS:88 eligible patients were treated with chemotherapy comprised of carboplatin AUC of 6, IV da...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.92279
更新日期:2011-10-01 00:00:00
abstract::This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated u...
journal_title:Indian journal of cancer
pub_type: 历史文章,杂志文章
doi:10.4103/ijc.IJC_13_19
更新日期:2019-07-01 00:00:00
abstract::This note presents a brief account of the ideas and efforts of V.R. Khanolkar in the period 1952-1962 to develop the Indian Cancer Research Centre into a "center of excellence". Khanolkar, who is recognized as a pioneer in cancer research in India, focused on developing multidisciplinary medical research and mentored ...
journal_title:Indian journal of cancer
pub_type: 传,历史文章,杂志文章
doi:10.4103/ijc.IJC_14_19
更新日期:2019-10-01 00:00:00
abstract:Background:Gestational trophoblastic neoplasia (GTN) are a spectrum of tumors that develop from placental tissue. We aimed to evaluate the management and treatment outcome of GTN. Methods:Patients diagnosed with GTN presented to Kasr Alainy Center of Clinical Oncology between 2008 and 2017 were included in this study....
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_551_19
更新日期:2021-01-06 00:00:00
abstract:INTRODUCTION:Fluorouracil (FU)based chemoradiotherapy is regarded as a standard perioperative treatment in locally advanced rectal cancer. Capecitabine is an oral fluoropyrimidine that generates 5FU preferentially at the tumor site by exploiting the higher activity of the enzyme thymidine phosphorylase in tumor tissue ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/ijc.IJC_174_17
更新日期:2017-01-01 00:00:00
abstract::Histopathological findings in 57 surgical specimens of T3 and T4 buccal mucosa cancers are reviewed. The incidence of the well-differentiated tumours (including verrucous carcinoma) was 61%. A moderate degree of lymphocytic infiltration of the tumour was present in 37% of patients. Histologically proven cervical lymph...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_343_20
更新日期:2020-04-01 00:00:00
abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_542_18
更新日期:2020-04-01 00:00:00
abstract::We report a rare case of 'metastatic invasive mole' to the spinal cord causing paraplegia in a 19-year-old woman. There are no such histologically proven reports in the literature since the use of the tumour marker, beta-subunit of human chorionic gonadotrophin (beta-HCG) and chemotherapy. We stress the importance of ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Giant-cell Tumours (GCT) of bone are not uncommon but a primary multicentric giant-cell tumour is very rare. This reported case represents a true multicentric giant-cell tumour with four lesions. These lesions had only curettage with no recurrence. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:The Medical Oncology Department at Tata Memorial Hospital, the single largest tertiary cancer care center in Asia, receives in-house registered and referral patient samples from all parts of the country. Our recent studies establish 23% EGFR mutation frequency among Indian population. Here, we extend our stu...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.117023
更新日期:2013-04-01 00:00:00
abstract::Cytogenetic analysis using G-banding techniques for the diagnosis of malignancy in pleural and peritoneal effusions is compared with the results of traditional cytomorphology. The studies indicate that the yield of mitotic cells in malignant effusions is quite high when compared to fluids with no cytological evidence ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00