Abstract:
:Histopathological findings in 57 surgical specimens of T3 and T4 buccal mucosa cancers are reviewed. The incidence of the well-differentiated tumours (including verrucous carcinoma) was 61%. A moderate degree of lymphocytic infiltration of the tumour was present in 37% of patients. Histologically proven cervical lymph node deposits were present in only 16% of the patients. Amongst the group of patients with clinically enlarged lymph nodes, metastatic disease was histologically demonstrated in 17.5% at level I and 14% at level II of neck nodes. Amongst group of patients with no palpable nodes in the neck, metastatic disease was histologically demonstrated in 11.7% at level I and 9% at level II of neck nodes. These findings contra-indicate an elective neck dissection and indicate the need to confirm histologically the presence of lymph node deposits doing a radical neck dissection in patients with buccal mucosa cancer. This well-differentiated tumour has a much lower tendency to metastasize than cancers in other sites of the oral cavity.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Dhawan IK,Verma K,Khazanchi RK,Madan NC,Shukla NK,Saxena Rsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
176-80issue
4eissn
0019-509Xissn
1998-4774journal_volume
30pub_type
杂志文章abstract:BACKGROUND:The three direct factors that could lead cancer patients to anemia, apart from therapy are iron deficiency, inflammatory cytokines surge and decreased erythropoietin (Epo). Our aim was to quantify biochemical and hematologic markers serum Epo, ferritin (Fe) and tumor necrosis factor-alpha (TNF-α) along with ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.175579
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The aim of this prospective study was to evaluate the effects of radiotherapy (RT) on psychiatric disorder in patients undergoing RT for head and neck cancer. MATERIALS AND METHODS:The prospective study included 51 patients with head and neck cancer. The diagnosis of psychiatric disorder was made by Diagnostic...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.180816
更新日期:2016-01-01 00:00:00
abstract:PURPOSE OF THE STUDY:To analyze the role of hypofractionated radiotherapy in advanced carcinoma of cervix. BASIC PROCEDURE:Medical records of 62 women with advanced carcinoma cervix III3 treated during 1994-1996 were reviewed. Patients were treated with standard pelvic portals to a total dose of 39Gy in 13 fractions o...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_542_18
更新日期:2020-04-01 00:00:00
abstract::The use of cell phones is increasing worldwide at a phenomenal pace. While cellular communication has dramatically influenced our lifestyle, its impact on human health has not been completely assessed. Widespread concern continues in the community about the deleterious effects of radiofrequency radiations (with which ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509x.48589
更新日期:2009-01-01 00:00:00
abstract::Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/ijc.IJC_258_17
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Preoperative risk estimation evaluating mortality and morbidity might help surgical decision. AIMS:The aim of this study was to compare the sensitivities of physiologic and operative severity score for the enumeration of mortality and morbidity (POSSUM), portsmouth-POSSUM (P-POSSUM), colorectal-POSSUM (CR-P...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.175318
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Adrenal cortical carcinoma (ACC) is an uncommon cancer. MATERIALS AND METHODS:The author performed a literature review on the reports of ACC in Thailand in order to summarize the characteristics of this rare cancer among Thai patients. RESULTS:According to this study, there have been at least seven reports...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.123611
更新日期:2013-10-01 00:00:00
abstract::Wide resection of bone tumour has become an accepted treatment in the limb salvage surgery. The reconstruction of the residual defect following wide resection is a major problem. The motions of involved joint after resection of the large tumour can be restored by using either the osteoarticular allograft or endoprosth...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
abstract:INTRODUCTION:There is limited data from India regarding elderly non-Hodgkin's lymphomas (NHL) patients. Hence, this audit was planned to study the clinic-pathological features and treatment outcomes in elderly NHL patients. METHODS:Retrospective analysis of all NHL patients above age of 59 years treated at the author'...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.178434
更新日期:2015-10-01 00:00:00
abstract::The incidence of late complications for different size of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1 and 52 cases with T2 lesions. Radical radiotherapy was given with three different regimens having dose per fraction as 3.33, 2.5 an...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:A relatively new development in the arena of prostatic histopathological study is the premalignant proliferative changes in the glandular epithelium, possibly relating to carcinoma. Two major categories have come up, namely prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia (AAH)....
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract:Background and Objectives:Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_466_17
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The prognostic relevance of histologic differentiation in gastric carcinoma patients with curative resection is unclear. We analyzed the clinicopathologic features of gastric carcinoma patients with curative resection according to the histologic differentiation and evaluated surgical outcome. MATERIALS AND ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.175569
更新日期:2015-01-01 00:00:00
abstract::Uncommon patterns of presentation of acute leukemia pose diagnostic problems. A rheumatological prodrome in acute myeloblastic leukemia is very rare. We describe one such patient who had a normal haemogram. Bone marrow examination done later revealed acute myeloblastic leukemia. The case is discussed with reference to...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:There is limited Indian data on clinical profile and treatment outcomes for patients with Stage IV adenocarcinoma of lung. AIM:We aimed to prospectively study the clinical profile and treatment outcomes for patients with Stage IV adenocarcinoma of lung at a tertiary cancer center. MATERIALS AND METHODS:One...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.219595
更新日期:2017-01-01 00:00:00
abstract::Available data on cancer mortality in the combined employee populations of five units of the Department of Atomic Energy, namely those in Mumbai, Tarapur, Kalpakkam, Hyderabad and Alwaye, with study periods ranging between 13 and 21 years, have been analysed. Data are available only on those still serving, i.e., subje...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Seroma formation after mastectomy typically delays recovery and adds to morbidity. AIMS:This retrospective review was undertaken to identify factors which predict development of seroma after mastectomy for breast cancer patients. SETTING AND DESIGN:119 consecutive patients intended for mastectomy for the t...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.38940
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Plumbagin (5-hydroxy-2-methyl-1,4-napthoquinone) derived from Plumbago species is a potential anti-tumour agent. Plumbagin has been tested for anti-cancer activity in vitro and in vivo using mice model. AIM:To study the tumour suppressing efficacy of plumbagin using zebrafish model. MATERIALS AND METHODS:H...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.219580
更新日期:2017-01-01 00:00:00
abstract:AIMS AND BACKGROUND:The immunoprofile of the Reed Sternberg cell with respect to immunoreactivity for CD20 and lack of CD15 has been described as a poor prognostic factor. Large scale studies analyzing the immunoprofile of Hodgkin's lymphoma (HL) from India are lacking. The aim of this study was to obtain baseline info...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.41772
更新日期:2008-04-01 00:00:00
abstract::In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic chemicals in tobacco and other ingredients added to various products are causally associated with several non-communicable diseases includi...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.107735
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Mitochondrial DNA (Mt DNA) defects have been identified in a variety of Tumors, but the exact role of these defects in the pathogenicity and tumor progression is poorly understood. This study aims at identifying the status of mitochondrial OXPHOS genes in neoplastic transformation and attempts to establish a...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.118732
更新日期:2013-07-01 00:00:00
abstract::We described a 41-year-old patient with acute promyelocytic leukemia (APL) who experienced two successive relapses: one after all-trans retinoic acid (ATRA) treatment and chemotherapy, and another after ATRA treatment and chemotherapy, followed by autologous peripheral blood stem cell transplantation. A third complete...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::Rat sarcoma viral oncogene homolog (RAS) and B-Raf murine sarcoma viral oncogene homolog B1 (BRAF) are members of the same signaling pathway (RAS-RAF-mitogen-activated protein kinase (MAPK) in colorectal cancer (CRC). It is generally assumed that BRAF mutations are seen only with wild-type RAS in CRC. But RAS and BRAF...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_430_18
更新日期:2019-04-01 00:00:00
abstract::Despite multimodality treatment protocol including surgical resection, radiotherapy, and chemotherapy in patients with glioblastoma multiforme (GBM), most suffer from treatment failure and tumor recurrence within a few months of initial surgery. The effectiveness of temozolomide (TMZ), the most commonly used chemother...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509X.178403
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Metaplastic breast carcinoma (MBC) is a rare disease with incidence of less than 1%. MBC present with a larger tumor size, less number of nodes involved, mostly undifferentiated triple negative tumors. We aimed to determine progression-free and overall survival and reported hospital-based incidence of MBC. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_731_18
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor of adolescent males and there is a paucity of Indian studies on this subject. AIMS:To present the experience of management of JNA at a single institution. SETTING AND DESIGN:This is a retrospective observational study of patients with JNA who prese...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.15098
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Fluorouracil (FU)based chemoradiotherapy is regarded as a standard perioperative treatment in locally advanced rectal cancer. Capecitabine is an oral fluoropyrimidine that generates 5FU preferentially at the tumor site by exploiting the higher activity of the enzyme thymidine phosphorylase in tumor tissue ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/ijc.IJC_174_17
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The Medical Oncology Department at Tata Memorial Hospital, the single largest tertiary cancer care center in Asia, receives in-house registered and referral patient samples from all parts of the country. Our recent studies establish 23% EGFR mutation frequency among Indian population. Here, we extend our stu...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.117023
更新日期:2013-04-01 00:00:00
abstract:INTRODUCTION:Multiple myeloma (MM) is a B-cell malignancy accounting for 0.8% of all cancer deaths globally. This malignancy is characterized by lytic bone disease renal insufficiency, anemia, hypercalcemia, and immunodeficiency. The myeloma cells have enhanced expression of CD138. CD138 is a transmembrane heparin sulf...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_349_17
更新日期:2017-07-01 00:00:00