Abstract:
BACKGROUND:Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor of adolescent males and there is a paucity of Indian studies on this subject. AIMS:To present the experience of management of JNA at a single institution. SETTING AND DESIGN:This is a retrospective observational study of patients with JNA who presented at the Tata Memorial Hospital between May 1988 and August 2001. MATERIALS AND METHODS:Thirty-two patients with JNA were treated in the study period. Since the time period was prolonged and diagnostic and therapeutic protocols had undergone many changes, the patients were divided into two groups, namely 1988-1996 and 1997-2001. The age distribution, disease patterns, management approaches and treatment outcomes of patients in the two groups were recorded. Statistical analyses were done using students 't' test and test for proportion. RESULTS:The mean age at presentation was 16 years and more than 90% of the patients had Stage III or IV disease. Preoperative embolization was carried out in 19 patients. The surgical approaches used were median maxillectomy, infratemporal fossa, transpalatal, maxillary swing and craniofacial approach. The recurrence rate, complete resection rate and cure rates were 12.5%, 41% and 63% respectively. CONCLUSION:Surgery is the mainstay of treatment of JNA. Preoperative embolization and newer surgical approaches result in less blood loss and complete resection. Aggressive re-resection should be done for resectable recurrences reserving radiotherapy for unresectable, recurrent/ residual disease.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Mistry RC,Qureshi SS,Gupta S,Gupta Sdoi
10.4103/0019-509x.15098keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
35-9issue
1eissn
0019-509Xissn
1998-4774journal_volume
42pub_type
杂志文章abstract::Uncommon patterns of presentation of acute leukemia pose diagnostic problems. A rheumatological prodrome in acute myeloblastic leukemia is very rare. We describe one such patient who had a normal haemogram. Bone marrow examination done later revealed acute myeloblastic leukemia. The case is discussed with reference to...
journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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doi:
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
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journal_title:Indian journal of cancer
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doi:
更新日期:2003-10-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
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更新日期:1991-12-01 00:00:00
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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更新日期:1997-12-01 00:00:00
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pub_type: 杂志文章
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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