Abstract：
:In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic chemicals in tobacco and other ingredients added to various products are causally associated with several non-communicable diseases including cancer, especially oral cancer, which is the leading cancer among men and the third most common cancer among women in India. This article highlights the toxicity, mutagenecity and carcinogenic effects of hazardous chemicals present in smokeless tobacco products. This endeavor was based on the extensive review of literature from various sources. The SLT products have influence on cellular metabolism, ability to cause DNA damage, and cancer in experimental animals. It is, therefore, essential to consider the collective role of chemical constituents of SLT products in the causation of adverse effect on human health.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Bhisey RAdoi
10.4103/0019-509X.107735subject
Has Abstractpub_date
2012-10-01 00:00:00pages
364-72issue
4eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2012_49_4_364_107735journal_volume
49pub_type
杂志文章,评审abstract：CONTEXT:Tumor budding (TBud) is recognized as a poor prognostic marker in colorectal cancer (CRC) with important treatment implications in Stage II cancers and malignant polyps. There are multiple propositions for bud count reporting but without an uniformly accepted system. The International TBud consensus conference ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_642_17
更新日期：2017-10-01 00:00:00
abstract：:Gliomatosis cerebri is a vary rare neoplastic lesion of the central nervous system. An intra-vitam diagnosis of gliomatosis cerebri can be suggested with a steleolactic biopsy of the lesion in conjunction with Magnetic Resonance Imaging (MRI) findings in the brain. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND:Seroma formation after mastectomy typically delays recovery and adds to morbidity. AIMS:This retrospective review was undertaken to identify factors which predict development of seroma after mastectomy for breast cancer patients. SETTING AND DESIGN:119 consecutive patients intended for mastectomy for the t...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.38940
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Risk stratification of patients with febrile neutropenia (FN) into those at "High Risk" and "Low Risk" of developing complications helps in making decisions regarding optimal treatment, such as whether to treat with oral or intravenous antibiotics, whether to treat as inpatient or outpatient and how long to ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.175321
更新日期：2014-10-01 00:00:00
abstract：:In the cervical cancer cases registered at the Cancer Hospital at Barshi, India during 1988-90, 99 of the 105 cases were clinically staged (Total number of cases registered: 136). The annual number of cases were too few for a comparison of stage distribution between the registry years. However, comparison of the propo...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVE:Due to the low sensitivity of Pap smear, premalignant lesions of the cervix can be missed in women with inflammatory Pap smears. However, it is not practically possible to subject all women with inflammatory Pap smear to colposcopy. This study was carried out with the aim to evaluate whether women with persis...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.82901
更新日期：2011-04-01 00:00:00
abstract：:Six patients of primary lymphoma of breast are presented. All our patients were female with median age of 46 years. Combination chemotherapy was the mainstay of treatment in all the patients. Five patients achieved complete remission of which two relapsed, one had a distant relapse and the other was local. Patient wit...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:Gastrointestinal tract (GI) is the most frequently involved extra nodal site in non-Hodgkin's lymphoma (NHL). Surgery, radiotherapy and chemotherapy (CT) have been used mostly in various combinations, but lately chemotherapy alone has emerged as an effective option. The purpose of this study is to evaluate e...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.25773
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:This retrospective study was performed in a tertiary care center from India analyzing the histopathological reports and the clinical data of the adult patients admitted in this institute with a diagnosis of renal tumors and had undergone nephrectomy for the disease. OBJECTIVE:The objective of this study is ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.180837
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:We have reported here the 5-year incidence (2004-2008) of gallbladder cancer (GBC) in North Central India along with its descriptive epidemiology. This provides potential clues for better prevention. The present study has also evaluated the association of ABO blood groups with GBC. PATIENTS AND METHODS:The ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.176736
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Multiple endocrine neoplasia type 2A (MEN 2A) is an autosomal dominant inherited cancer syndrome that affects multiple tissues derived from the neural crest. Inheritance of MTC is related to the presence of specific mutations in the RET proto-oncogene. Almost all mutations in MEN 2A involve one of the cystei...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.27934
更新日期：2006-07-01 00:00:00
abstract：INTRODUCTION:In our center, we routinely use CCNU (Lomustine) as salvage treatment in high-grade glioma patients who cannot afford bevacizumab. This exploratory analysis was done to report the efficacy and toxicity associated with this regimen. METHODS:Patients who were treated with salvage CCNU (postexposure to temoz...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.204774
更新日期：2016-10-01 00:00:00
abstract：:A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the re...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_349_18
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION:In our study, we have treated cases of early glottic carcinoma by two different dose-fractionation schedules in relation to overall treatment time. MATERIALS AND METHODS:This is an analysis of 29 patients with invasive, previously untreated T1and T2squamous cell carcinoma of true vocal cord that was treat...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.200677
更新日期：2016-07-01 00:00:00
abstract：:Cancer is a manifestation of dysregulated gene function arising from a complex interplay of oncogenes and tumor suppressor genes present in our body. Cancer has been constantly chased using various therapies but all in vain as most of them are highly effective only in the early stages of cancer. Recently, RNA interfer...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.175598
更新日期：2015-01-01 00:00:00
abstract：:It is important to differentiate non-dyplastic aplastic anaemia from hypocellular myelodysplastic syndrome (MDS). Four patients presenting with hypocellular bone marrow and different evolution patterns are being described. Certain morphological features and variable hypocellularity were found to be useful indices for ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION:This study was undertaken to evaluate the clinicopathological characteristics of patients with breast cancer at our institute, a tertiary-care cancer center in northern India. MATERIALS AND METHODS:This retrospective study included all patients with breast cancer registered at our institute from January 1...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_73_18
更新日期：2018-07-01 00:00:00
abstract：:Isolated central nervous metastasis is rare in patients with Ewing's sarcoma. Here we report two cases with CNS metastasis as the sole manifestation of relapse with a brief review of the literature. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：PURPOSE OF THE STUDY:To analyze the role of hypofractionated radiotherapy in advanced carcinoma of cervix. BASIC PROCEDURE:Medical records of 62 women with advanced carcinoma cervix III3 treated during 1994-1996 were reviewed. Patients were treated with standard pelvic portals to a total dose of 39Gy in 13 fractions o...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：:Gliomatosis peritonei (GP), a rare condition related to ovarian teratomas, is characterized by miliary implants of mature glial tissues on the peritoneum or omentum. We report herein a case of mature teratoma of the ovary with GP with imaging features and pathological correlation. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.17064
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND AND AIMS:Radiation induced wet desquamation of skin in carcinoma breast patients is a painful condition. In this study topical beclomethasone dipropionate spray was used as prophylaxis with the purpose of reducing risk of the wet desquamation of skin in irradiated field. MATERIALS AND METHODS:Sixty patients...
journal_title：Indian journal of cancer
pub_type： 杂志文章,随机对照试验
doi：10.4103/0019-509x.29424
更新日期：2006-10-01 00:00:00
abstract：INTRODUCTION:: Indian families are known for adopting the role of caregiver naturally when someone in the family falls ill to cancer. Although there were strong family structure and system existed here, now the changing family pattern and structure are challenging the role of cancer caregiving as well. OBJECTIVE:: Thi...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_211_17
更新日期：2017-04-01 00:00:00
abstract：INTRODUCTION:Historically, metastatic renal cell carcinoma (RCC) has had poor prognosis; the outcomes have improved with the introduction of tyrosine-kinase inhibitors, such as sunitinib. There is no reported literature from India on the use of sunitinib in metastatic RCC. We present an analysis of sunitinib at our ins...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.118725
更新日期：2013-07-01 00:00:00
abstract：:The incidence of late complications for different size of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1 and 52 cases with T2 lesions. Radical radiotherapy was given with three different regimens having dose per fraction as 3.33, 2.5 an...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral neuropathy can markedly dete...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_361_18
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:We aimed to study the compliance and treatment outcome of patients who received adjuvant treatment following curative resection for periampullary cancers periampullary cancers. MATERIALS AND METHODS:Institute medical records of PAC treated during 2007-2014 were retrieved. Demographics, treatment, and outcom...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_358_17
更新日期：2017-07-01 00:00:00
abstract：:Ten patients of the advanced malignant germ cell tumours of the ovary were treated by cisplatin based combination chemotherapy after initial conservation surgery. Eight patients completed course containing cisplatinum, vinblastine and bleomycin. Five patients (62.5%) achieved CR while 2 (25%) attained PR. One patient ...
journal_title：Indian journal of cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:Alpha-fetoprotein secreting (AFP) Sertoli-Leydig cell tumors of ovary (SLCT) are now identified as a distinct entity among the uncommon group of sex cord tumors of ovary. We report an unusual case of recurrent AFP secreting ovarian tumors and as ileocecal mesenteric cyst in a 25-year-old patient resulting in difficult...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.48599
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to evaluate the efficacy and safety of pemetrexed chemotherapy combined with intrapleural injection of pemetrexed and bevacizumab in the treatment of malignant pleural mesothelioma (MPM)-mediated malignant pleural effusion, and analyze the objective response rate (ORR), the me...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.154058
更新日期：2014-03-01 00:00:00
abstract：:Available data on cancer mortality in the combined employee populations of five units of the Department of Atomic Energy, namely those in Mumbai, Tarapur, Kalpakkam, Hyderabad and Alwaye, with study periods ranging between 13 and 21 years, have been analysed. Data are available only on those still serving, i.e., subje...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
