Abstract：
INTRODUCTION:In our study, we have treated cases of early glottic carcinoma by two different dose-fractionation schedules in relation to overall treatment time. MATERIALS AND METHODS:This is an analysis of 29 patients with invasive, previously untreated T1and T2squamous cell carcinoma of true vocal cord that was treated by radical radiation therapy. DOSE AND FRACTIONATION:All patients were treated with a continuous course of radiation therapy with once-daily fractionation. All the patients were treated 5 days a week from Monday to Friday. The fractionation regime was either: (1) 62.5 Gy/25fractions/5 weeks at 2.5 Gy fractions (Regimen 1), (2) 70 Gy/35 fractions/7 weeks at 2 Gy/fraction (Regimen 2). Regimen 1 included 15/29 patients (51.72%) and Regimen 2 included 14/29 patients (48.27%). Patients were evaluated for: (1) Locoregional control, (2) acute and late radiation toxicities, (3) quality of voice. RESULTS AND OBSERVATION:There was no significant difference in terms of locoregional control rate, acute and late radiation toxicities in both groups. Voice quality during and after radiation was comparable in both arms. CONCLUSION:Use of high dose per fraction schedule with shorter duration of treatment results in comparable local control as well as the quality of voice to the protracted course of radiotherapy without increase in treatment-related toxicities. Shorter overall treatment time can be of great advantage in terms of time, cost, comfort, and acceptability by the patients.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Alam MS,Perween R,Siddiqui SAdoi
10.4103/0019-509X.200677subject
Has Abstractpub_date
2016-07-01 00:00:00pages
402-407issue
3eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2016_53_3_402_200677journal_volume
53pub_type
杂志文章abstract：INTRODUCTION:Sri Lanka became a signatory to the WHO Frame Work Convention on Tobacco Control in September 2003, and this was ratified in November 2003. With a view to reduce the use of tobacco in Sri Lanka, the National Authority on Tobacco and Alcohol Act (NATA) No. 27 of 2006 was implemented. AIM:To assess the beha...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.107753
更新日期：2012-10-01 00:00:00
abstract：:Oral Metastasis from a carcinoma of the urinary Bladder is extremely uncommon. Two cases of transitional cell carcinoma of the Bladder, presenting eighteen and ten months after initial diagnosis, one with soft tissue metastasis in the upper alveolus and the other with bony metastasis to the mandible are discussed. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Breast cancer is the second most common cancer in the Indian female population. As per our hospital data, breast cancer is also found to be the second leading malignancy in women. Hence, we undertook this study to evaluate the clinical profile, histopathologic types, grade, stage and the progn...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.123594
更新日期：2013-10-01 00:00:00
abstract：:This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated u...
journal_title：Indian journal of cancer
pub_type： 历史文章,杂志文章
doi：10.4103/ijc.IJC_13_19
更新日期：2019-07-01 00:00:00
abstract：:Basaloid Squamous Carcinoma (BSC) is an uncommon aggressive neoplasm occurring in the upper aerodigestive tract. Lung as a primary site has only recently been reported. A combination of microscopic features is required to make a diagnosis and to differentiate it from other more common malignancies in these sites. Thre...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：:Casual Interpretation of results in a given article has several pitfalls. In order to assess the strengths and limitations of a given article several factors need to be considered. This review article is intended to list, classify and describe briefly the factors that should be considered in the evaluation of an artic...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：:Gliomatosis cerebri is a vary rare neoplastic lesion of the central nervous system. An intra-vitam diagnosis of gliomatosis cerebri can be suggested with a steleolactic biopsy of the lesion in conjunction with Magnetic Resonance Imaging (MRI) findings in the brain. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Giant-cell Tumours (GCT) of bone are not uncommon but a primary multicentric giant-cell tumour is very rare. This reported case represents a true multicentric giant-cell tumour with four lesions. These lesions had only curettage with no recurrence. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：BACKGROUND:We have reported here the 5-year incidence (2004-2008) of gallbladder cancer (GBC) in North Central India along with its descriptive epidemiology. This provides potential clues for better prevention. The present study has also evaluated the association of ABO blood groups with GBC. PATIENTS AND METHODS:The ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.176736
更新日期：2015-07-01 00:00:00
abstract：AIM OF STUDY:To investigate the trend of expression of liver function test enzymes and other biochemical changes during gallbladder carcinogenesis. MATERIALS AND METHODS:Eight hundred and seventy-eight gallbladder disease patients were selected to study the liver function test enzymes and routine blood biochemical cha...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.98938
更新日期：2012-01-01 00:00:00
abstract：PURPOSE OF THE STUDY:To analyze the role of hypofractionated radiotherapy in advanced carcinoma of cervix. BASIC PROCEDURE:Medical records of 62 women with advanced carcinoma cervix III3 treated during 1994-1996 were reviewed. Patients were treated with standard pelvic portals to a total dose of 39Gy in 13 fractions o...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：INTRODUCTION:In our center, we routinely use CCNU (Lomustine) as salvage treatment in high-grade glioma patients who cannot afford bevacizumab. This exploratory analysis was done to report the efficacy and toxicity associated with this regimen. METHODS:Patients who were treated with salvage CCNU (postexposure to temoz...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.204774
更新日期：2016-10-01 00:00:00
abstract：:Positron emission tomography (PET) has emerged as an important diagnostic tool in the management of lung cancers. Although PET is sensitive in detection of lung cancer, but FDG (2-deoxy-2- 18 fluro-D-glucose) is not tumor specific and may accumulate in a variety of nonmalignant conditions occasionally giving false pos...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509x.44660
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To evaluate the outcome of patients of renal cell carcinoma (RCC) with inferior vena caval (IVC) thrombus treated by radical nephrectomy and IVC thrombectomy in terms of clinical and pathological factors and prognosis. MATERIALS AND METHODS:Sixty-three consecutive patients of RCC with IVC thrombus who underwen...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.35810
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:This retrospective study was performed in a tertiary care center from India analyzing the histopathological reports and the clinical data of the adult patients admitted in this institute with a diagnosis of renal tumors and had undergone nephrectomy for the disease. OBJECTIVE:The objective of this study is ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.180837
更新日期：2016-01-01 00:00:00
abstract：:Colloid cyst is a rare benign intracranial neoplasm, commonly located in the third ventricle. Though headache and visual symptoms are classical, the patients may present with sudden neurological deterioration. We present a ten-year-old male child who presented with sudden neurological deterioration due to colloid cyst...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:During the last 11 years, 101 patients of Wilms tumor were seen. Of these, 13 patients had metastatic disease at onset while 24 patients presented with relapse at a latter date. Seven patients have been cured, all had favourable histology. The risk factors associated with relapse were found to be unfavourable histolog...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Prostate cancer is one of the most common malignancies of elderly males. Management depends on the accurate estimation of disease both at initial diagnosis and in its subsequent course. In the present study, we evaluated the diagnostic utility of positron emission tomography with 18 F-fluorodeoxyglucose (FDG-PET) in p...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.73572
更新日期：2010-10-01 00:00:00
abstract：:We report a rare case of 'metastatic invasive mole' to the spinal cord causing paraplegia in a 19-year-old woman. There are no such histologically proven reports in the literature since the use of the tumour marker, beta-subunit of human chorionic gonadotrophin (beta-HCG) and chemotherapy. We stress the importance of ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:Treatment of cancer is limited by affordability of patients in the many developing countries including India. Generic drug manufacturers have responded to this scenario by making drugs available at affordable costs, often at less than 10% the cost of the original brand. In our practice, it is found that there is a thr...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.146723
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-known adverse effect of vincristine (VCR). Literature suggests that Asians are predisposed to develop SIADH following VCR administration. However, data regarding the occurrence of SIADH in children with malignancy are limited. This st...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_737_18
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Pediatric acute lymphoblastic leukemia (ALL) is a biologically heterogeneous disease and socioeconomic and environmental factors are considered to be an important determinant of its immunophenotype. The aim of this analysis is to study the time trend in the immunophenotype of pediatric acute lymphoblastic le...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.84932
更新日期：2011-07-01 00:00:00
abstract：:Chylothorax is an uncommon complication in children. Although surgery and trauma are the most common causes encountered, hematological as well as solid malignancies can present with chylothorax. This study aimed to describe the presentation and management of malignant chylothorax in children. This is a case series fro...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_499_17
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Invasion and metastasis are the most strenuous problems in the management of breast cancer. These events require diverse proteolytic enzymes, among which MMP-2 and MMP-9 play a significant role in degradation of type IV collagen, the major component of the basement membrane. Therefore, the major objective of...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.52953
更新日期：2009-07-01 00:00:00
abstract：:Wide resection of bone tumour has become an accepted treatment in the limb salvage surgery. The reconstruction of the residual defect following wide resection is a major problem. The motions of involved joint after resection of the large tumour can be restored by using either the osteoarticular allograft or endoprosth...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Increasing incidence of squamous cell carcinoma (SCC) of the oral cavity and oropharynx is reported in young adults. However, there is a paucity regarding etiology and risk factors. AIM:To evaluate the exposure potential carcinogenic factors among a sample aged 45 years and younger, diagnosed with SCC of th...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.197725
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Oral tyrosine kinase inhibitor (gefitinib and erlotinib) have been used in the palliative treatment of head and neck cancers with limited success. In this report, we aim to quantify the symptomatic benefit, progression-free survival (PFS) and overall survival (OS) when erlotinib is given as second-line treat...
journal_title：Indian journal of cancer
pub_type： 杂志文章,随机对照试验
doi：10.4103/0019-509X.178374
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Breast cancer in women aged less than 35 years is uncommon and accounts for 1-2% of all breast cancer in the West. There is a paucity of data on young breast cancer from India. The aim of this study was to analyze the clinical, pathological, prognostic factors and outcome in young breast cancer patients. MA...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.175332
更新日期：2014-10-01 00:00:00
abstract：:Sentinel node localization is the second most important development in this century after conservative lumpectomy for the treatment of early breast cancer. The sentinel node mapping is a new multidisciplinary approach for staging of axilla in an accurate and less morbid way as compared to axillary node dissection. Sen...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：:We have studied fibrinolytic activity of 12 cases of infiltrating duct carcinoma of breast (7 metastatic and 5 non-metastatic) and ten cases of adenocarcinoma of gastrointestinal tract (5 each of metastatic and nonmetastatic), and compared with some of their normal tissue counterparts. Both metastatic and non-metastat...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
