Abstract:
:We have studied fibrinolytic activity of 12 cases of infiltrating duct carcinoma of breast (7 metastatic and 5 non-metastatic) and ten cases of adenocarcinoma of gastrointestinal tract (5 each of metastatic and nonmetastatic), and compared with some of their normal tissue counterparts. Both metastatic and non-metastatic tumors of breast and gastrointestinal tract had significantly higher levels of fibrinolytic activity as compared to normal tissues. Though mean fibrinolytic activity (expressed as ug/ml of urokinase activity) of metastatic tumors of breast and gut had higher values as compared to non-metastatic counterparts, however it did not reach statistical significance.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Sarode R,Marwaha N,Gupta NMsubject
Has Abstractpub_date
1991-12-01 00:00:00pages
181-4issue
4eissn
0019-509Xissn
1998-4774journal_volume
28pub_type
杂志文章abstract::Gliomatosis cerebri is a vary rare neoplastic lesion of the central nervous system. An intra-vitam diagnosis of gliomatosis cerebri can be suggested with a steleolactic biopsy of the lesion in conjunction with Magnetic Resonance Imaging (MRI) findings in the brain. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Activating mutations in the epidermal growth factor receptor gene and rearrangement of the anaplastic lymphoma kinase gene exemplify the molecular characterization of nonsmall cell lung cancer (NSCLC), particularly adenocarcinoma, and its therapeutic relevance. Several genetic alterations with prognostic and predictiv...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/ijc.IJC_258_17
更新日期:2017-01-01 00:00:00
abstract::Three cases of damage to the optic nerves and chiasma following pituitary irradiation with Co60 teletherapy are described. All of them presented with progressive visual impairment months following irradiation and simulated recurrence of the tumour. CT scan was also not helpful in differentiating radionecrosis from tum...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract::Uncommon patterns of presentation of acute leukemia pose diagnostic problems. A rheumatological prodrome in acute myeloblastic leukemia is very rare. We describe one such patient who had a normal haemogram. Bone marrow examination done later revealed acute myeloblastic leukemia. The case is discussed with reference to...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:The utilization and extent of pelvic lymph node dissection (PLND) varies depending on the disease and practice patterns. AIMS:This study compares practice patterns in utilization of PLND between Indian and United States (US) practices. SETTINGS AND DESIGN:We focused on 415 patients (204 India; 211 US) pros...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_227_17
更新日期:2017-04-01 00:00:00
abstract::Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_545_17
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Ephrin A4 is one of the ephrin ligand molecules belonging to the tyrosine kinases receptor family. It was originally identified in a T-lymphoma cell line and seen to be expressed in human adult tissue as well as several tumor types. In our previous study, we showed the unique pattern of ephrin A4 immunohisto...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.58859
更新日期:2010-01-01 00:00:00
abstract:AIMS AND BACKGROUND:The immunoprofile of the Reed Sternberg cell with respect to immunoreactivity for CD20 and lack of CD15 has been described as a poor prognostic factor. Large scale studies analyzing the immunoprofile of Hodgkin's lymphoma (HL) from India are lacking. The aim of this study was to obtain baseline info...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.41772
更新日期:2008-04-01 00:00:00
abstract::L-asparaginase is a valuable chemotherapeutic agent used in the induction of remission and improvement of long term survival in patients with acute lymphoblastic leukemia. Hyperglycemia is a well known side effect of L-asparaginase. Fourteen patients developed hyperglycemia during induction therapy of acute lymphoblas...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::Giant-cell Tumours (GCT) of bone are not uncommon but a primary multicentric giant-cell tumour is very rare. This reported case represents a true multicentric giant-cell tumour with four lesions. These lesions had only curettage with no recurrence. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::This note presents a brief account of the ideas and efforts of V.R. Khanolkar in the period 1952-1962 to develop the Indian Cancer Research Centre into a "center of excellence". Khanolkar, who is recognized as a pioneer in cancer research in India, focused on developing multidisciplinary medical research and mentored ...
journal_title:Indian journal of cancer
pub_type: 传,历史文章,杂志文章
doi:10.4103/ijc.IJC_14_19
更新日期:2019-10-01 00:00:00
abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_542_18
更新日期:2020-04-01 00:00:00
abstract::A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the re...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_349_18
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:: Indian families are known for adopting the role of caregiver naturally when someone in the family falls ill to cancer. Although there were strong family structure and system existed here, now the changing family pattern and structure are challenging the role of cancer caregiving as well. OBJECTIVE:: Thi...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_211_17
更新日期:2017-04-01 00:00:00
abstract::Primary undifferentiated embryonal of the liver in children is a rare neoplasm with dismal prognosis. Surgery is the treatment of choice. Adjuvant chemotherapy may prove useful in improving the prognosis of these tumours. We report two cases of Primary undifferentiated embryonal sarcoma of the liver. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-12-01 00:00:00
abstract:INTRODUCTION:In our center, we routinely use CCNU (Lomustine) as salvage treatment in high-grade glioma patients who cannot afford bevacizumab. This exploratory analysis was done to report the efficacy and toxicity associated with this regimen. METHODS:Patients who were treated with salvage CCNU (postexposure to temoz...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.204774
更新日期:2016-10-01 00:00:00
abstract::Oral Metastasis from a carcinoma of the urinary Bladder is extremely uncommon. Two cases of transitional cell carcinoma of the Bladder, presenting eighteen and ten months after initial diagnosis, one with soft tissue metastasis in the upper alveolus and the other with bony metastasis to the mandible are discussed. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Lymphedema following breast cancer treatment is one of the most morbid conditions affecting breast cancer survivors. Currently, no therapy completely cures this condition. Comprehensive Decongestive Therapy (CDT), a novel physiotherapeutic method offers promising results in managing this condition. This ther...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.92250
更新日期:2011-10-01 00:00:00
abstract:Background and Objectives:Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_466_17
更新日期:2018-01-01 00:00:00
abstract::The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_343_20
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Second primary malignancy (SPM) is associated with decreased overall survival (OS) in laryngeal carcinomas (LC). METHODS:One hundred eighty three LC patients were analyzed retrospectively. The primary and secondary endpoints were the incidence of SPM and the OS difference between patients with and without...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_273_18
更新日期:2019-01-01 00:00:00
abstract:AIMS:The aim of this study is to investigate the activity and toxicity of etoposide with AUC 6 doses of carboplatin in patients with previously untreated extensive disease - small-cell lung cancer (SCLC). MATERIALS AND METHODS:88 eligible patients were treated with chemotherapy comprised of carboplatin AUC of 6, IV da...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.92279
更新日期:2011-10-01 00:00:00
abstract:CONTEXT:Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM:To study the cancer profile at Kolar, based on Pathology Depart...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.63011
更新日期:2010-04-01 00:00:00
abstract::Neuroendocrine tumors, including carcinoids account for less than 1% of gastric tumors. Various subtypes of gastric carcinoids have been reported earlier. The present case deals with two unusual presentations, diagnosis and course of a gastric neuroendocrine tumor in an adult patient. A 35-years-old male initially pre...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.16700
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Lymphoma combined with hepatitis B infection occupies a relatively higher incidence in China than that of in Europe and America. AIMS:To observe the efficacy and safety of rituximab in combination with chemotherapy in patients with B-cell non-Hodgkin's lymphoma (NHL) and hepatitis B virus (HBV) infection. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.200679
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Oral tyrosine kinase inhibitor (gefitinib and erlotinib) have been used in the palliative treatment of head and neck cancers with limited success. In this report, we aim to quantify the symptomatic benefit, progression-free survival (PFS) and overall survival (OS) when erlotinib is given as second-line treat...
journal_title:Indian journal of cancer
pub_type: 杂志文章,随机对照试验
doi:10.4103/0019-509X.178374
更新日期:2015-10-01 00:00:00
abstract:AIM:The clinical significance of Fas and FasL in hormone-sensitive carcinomas has been reported. Our objective was to evaluate the expression of apoptosis-regulating genes Fas and FasL in Indian breast cancer and fibroadenoma patients in relation to hormone receptor status. STUDY DESIGN:Retrospective. MATERIALS AND M...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.98921
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Sri Lanka became a signatory to the WHO Frame Work Convention on Tobacco Control in September 2003, and this was ratified in November 2003. With a view to reduce the use of tobacco in Sri Lanka, the National Authority on Tobacco and Alcohol Act (NATA) No. 27 of 2006 was implemented. AIM:To assess the beha...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.107753
更新日期:2012-10-01 00:00:00
abstract::The clinical microbiology department at CMC&H, Vellore in conjunction with the haematology department carries out routine surveillance of patients admitted to the hematology department. Since 1994 in a sample population of 55 patients with various underlying clinical conditions who have had bone marrow transplant, sep...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::Ketoconazole, an imidazole derivative is known to decrease adrenal steroid biosynthesis by inhibiting cytochrome P450 dependent adrenal enzymes. Three patients of adrenal carcinoma treated with ketoconazole, 600-1200 mg daily showed significant fall in plasma and urinary cortisol levels, but no reduction in tumor size...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00