Abstract:
AIM OF STUDY:To investigate the trend of expression of liver function test enzymes and other biochemical changes during gallbladder carcinogenesis. MATERIALS AND METHODS:Eight hundred and seventy-eight gallbladder disease patients were selected to study the liver function test enzymes and routine blood biochemical changes in the last five years (2004-08). Statistical analysis was performed using Graph Pad prism 5.02 software. RESULTS:The liver function test enzymes showed significant correlations among themselves, and with glucose in gallbladder cancer and gallstone disease patients (N = 878). Out of 878 gallbladder cases, 46 (5.24%) showed significantly higher glucose level of 216.66 mg/dL (P < 0.0001). All the three pathological conditions of gallbladder, gallbladder cancer with stones (GBCS), gallbladder cancer without stones (GBC) and calculus cholecystitis (CC), showed highly significant positive correlation (Pearson) between Serum Glutamic Oxaloactetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) [P < 0.0001, (GBCS); P < 0.0001, (GBC), and P < 0.0001, (CC)]. SGOT and SGPT also showed positive correlation with higher glucose level independently, in both GBCS and CC (P < 0.0001 and P < 0.0001), respectively. CONCLUSION:Simultaneous elevation of glucose and liver function test enzymes in GBC makes the diagnosis complex. Any patient of gallbladder diseases with higher level of glucose may have the possibility of developing gallbladder cancer.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Singh TD,Barbhuiya MA,Poojary S,Shrivastav BR,Tiwari PKdoi
10.4103/0019-509X.98938subject
Has Abstractpub_date
2012-01-01 00:00:00pages
125-36issue
1eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2012_49_1_125_98938journal_volume
49pub_type
杂志文章abstract::The use of colposcopy for follow up of patients with abnormal cervical smears has considerably increased the rate of detection of cervical malignancies and intraepithelial lesions in recent years. In case the lesion is situated high up in the cervical canal however, the chances of missing out the lesion are considerab...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::We described a 41-year-old patient with acute promyelocytic leukemia (APL) who experienced two successive relapses: one after all-trans retinoic acid (ATRA) treatment and chemotherapy, and another after ATRA treatment and chemotherapy, followed by autologous peripheral blood stem cell transplantation. A third complete...
journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
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abstract:BACKGROUND:The product of Wilms' tumor suppressor gene (WT1), a nuclear transcription factor, regulates the expression of the insulin-like growth factor (IGF) and transforming growth factor (TGF) systems, both of which are implicated in breast tumorigenesis and are known to facilitate angiogenesis. In the present study...
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.147474
更新日期:2014-12-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.180837
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_79_17
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.25773
更新日期:2006-01-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_73_18
更新日期:2018-07-01 00:00:00
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journal_title:Indian journal of cancer
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doi:10.4103/0019-509X.104065
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journal_title:Indian journal of cancer
pub_type: 杂志文章
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-12-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 传,历史文章,杂志文章
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journal_title:Indian journal of cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-09-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.176698
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journal_title:Indian journal of cancer
pub_type: 杂志文章
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更新日期:1993-06-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.200679
更新日期:2016-07-01 00:00:00
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.63011
更新日期:2010-04-01 00:00:00
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更新日期:2020-12-10 00:00:00