Abstract：
BACKGROUND:The Ewing sarcoma family of tumors (ESFT) are aggressive malignant tumors with small round cell morphology affecting mainly children and adolescents. The aim of this study is to classify the histological diversity and clinical characteristics of ESFT in children from a Tertiary Care Center in South India. MATERIALS AND METHODS:This retrospective descriptive study includes 51 cases of ES in children aged below 15 years. Clinical details were collected from case files. Histomorphological features were reviewed and tumors were subtyped into classic, primitive neuroectodermal tumor (PNET) and atypical variants along with immunohistochemical markers, cytogenetics, and fluorescence in situ hybridization (FISH). RESULTS:Fifty-three percent were female and 47% were male with mean age of 10 years. The most common site of involvement was skeletal involvement in 71%, followed by soft tissue involvement in 23%, and visceral involvement in 6%. Localized disease at presentation was seen in 44%, locally advanced disease in 28%, and metastatic disease in 28%. Recurrence was documented during follow-up in 18% of the cases. Histomorphologically, classic type was the most common (72%) followed by PNET (20%) category and atypical variant (8%). All cases were immunoreactive for CD99. Cytogenetic study in 12 cases showed translocation t(11;22) (q24;12) in 80% and variant translocations such as t(3;16), t(3;11) with nonspecific numerical abnormalities in 20%. FISH was carried out for documentation of four cases with atypical histomorphology. CONCLUSION:ESFT had wide histological variation which required confirmation by ancillary studies.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Priya D,Kumar RV,Appaji L,Aruna Kumari BS,Padma M,Kumari Pdoi
10.4103/0019-509X.176700subject
Has Abstractpub_date
2015-07-01 00:00:00pages
331-5issue
3eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2015_52_3_331_176700journal_volume
52pub_type
杂志文章abstract：:Gliomatosis peritonei (GP), a rare condition related to ovarian teratomas, is characterized by miliary implants of mature glial tissues on the peritoneum or omentum. We report herein a case of mature teratoma of the ovary with GP with imaging features and pathological correlation. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.17064
更新日期：2005-07-01 00:00:00
abstract：AIM OF STUDY:To investigate the trend of expression of liver function test enzymes and other biochemical changes during gallbladder carcinogenesis. MATERIALS AND METHODS:Eight hundred and seventy-eight gallbladder disease patients were selected to study the liver function test enzymes and routine blood biochemical cha...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.98938
更新日期：2012-01-01 00:00:00
abstract：:In vitro studies of chlorpromazine (CPZ) a popular anti-psychotic drug has shown radiation sensitizing effects at higher celluar concentration and protective effect at a lower concentration. The present study was designed to evaluate both sensitizing and protective effects in the treatment of advanced cancer of the ce...
journal_title：Indian journal of cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:The incidence of late complications for different size of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1 and 52 cases with T2 lesions. Radical radiotherapy was given with three different regimens having dose per fraction as 3.33, 2.5 an...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:Giant-cell Tumours (GCT) of bone are not uncommon but a primary multicentric giant-cell tumour is very rare. This reported case represents a true multicentric giant-cell tumour with four lesions. These lesions had only curettage with no recurrence. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:A total of forty bone marrow trephine biopsies and aspirates were studied from thirty five patients suffering from Hodgkin's disease during the two year period 1994 and 1995. Of these twenty five were at the time of diagnosis of the disease and fifteen after treatment. The biopsies were studied for incidence of involv...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：:A case report of a squamous cell carcinoma arising in a dermoid cyst of the ovary in a 29 year old patient is presented. Such an occurrence in young patients is unusual. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：Background and Objectives:Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_466_17
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:The aim was to evaluate the safety, feasibility and efficacy of computed tomography (CT)-guided percutaneous interstitial brachytherapy using radioactive iodine-125 ( 125 I) seeds for the treatment of lung cancer. MATERIALS AND METHODS:Included in this study were 45 male and 35 female patients aged 52-85 years...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.151999
更新日期：2015-02-01 00:00:00
abstract：:Cytogenetic analysis using G-banding techniques for the diagnosis of malignancy in pleural and peritoneal effusions is compared with the results of traditional cytomorphology. The studies indicate that the yield of mitotic cells in malignant effusions is quite high when compared to fluids with no cytological evidence ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Central nervous system (CNS) metastases are a frequent and severe complication associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC). The first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) have shown considerable efficacy in EGFR-mutated NSCLC. However, the...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/ijc.IJC_455_19
更新日期：2019-11-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.92279
更新日期：2011-10-01 00:00:00
abstract：INTRODUCTION:Fluorouracil (FU)based chemoradiotherapy is regarded as a standard perioperative treatment in locally advanced rectal cancer. Capecitabine is an oral fluoropyrimidine that generates 5FU preferentially at the tumor site by exploiting the higher activity of the enzyme thymidine phosphorylase in tumor tissue ...
journal_title：Indian journal of cancer
pub_type： 杂志文章,随机对照试验
doi：10.4103/ijc.IJC_174_17
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Mitochondrial DNA (Mt DNA) defects have been identified in a variety of Tumors, but the exact role of these defects in the pathogenicity and tumor progression is poorly understood. This study aims at identifying the status of mitochondrial OXPHOS genes in neoplastic transformation and attempts to establish a...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.118732
更新日期：2013-07-01 00:00:00
abstract：:Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral neuropathy can markedly dete...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_361_18
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:This study was undertaken to evaluate the clinicopathological characteristics of patients with breast cancer at our institute, a tertiary-care cancer center in northern India. MATERIALS AND METHODS:This retrospective study included all patients with breast cancer registered at our institute from January 1...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_73_18
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Increasing incidence of squamous cell carcinoma (SCC) of the oral cavity and oropharynx is reported in young adults. However, there is a paucity regarding etiology and risk factors. AIM:To evaluate the exposure potential carcinogenic factors among a sample aged 45 years and younger, diagnosed with SCC of th...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.197725
更新日期：2016-04-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:Alpha-fetoprotein secreting (AFP) Sertoli-Leydig cell tumors of ovary (SLCT) are now identified as a distinct entity among the uncommon group of sex cord tumors of ovary. We report an unusual case of recurrent AFP secreting ovarian tumors and as ileocecal mesenteric cyst in a 25-year-old patient resulting in difficult...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.48599
更新日期：2009-01-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：CONTEXT:Malnutrition is prevalent in children with cancer at diagnosis, especially in low- and middle-income countries (LMIC) where the great majority of children live. It is associated with an added burden of morbidity and mortality. AIMS:Answers were sought to the best measure of nutritional status in LMIC, the impa...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.175827
更新日期：2015-04-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.117023
更新日期：2013-04-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 临床试验,杂志文章
doi：10.4103/0019-509X.75838
更新日期：2011-01-01 00:00:00
abstract：:Resection or loss of a portion of the mandible can result in a variety of functional, cosmetic and psychological deficits that are dependent on the extent of the defect, the concomitant therapy and the timing of rehabilitative efforts. These impairments greatly affect the patient's Quality of life (QOL). The thrust in...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.112282
更新日期：2013-01-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-09-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.175805
更新日期：2015-04-01 00:00:00
abstract：Background:Low- and middle-income countries require to specify early detection programs and intervention models for breast cancer. The aim of this study was to assess the performance efficacy of an Iraqi early detection model in terms of cancer detection rate (CDR) and the method of participation in this program. Mate...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_633_17
更新日期：2018-01-01 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_470_19
更新日期：2020-11-24 00:00:00
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journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
