Characterization and immunogenicity of the CagF protein of the cag pathogenicity island of Helicobacter pylori.

abstract：:Corynebacterium renale type I (strain 115), 1.7 X 10(7) to 4.5 X 10(7) organisms, introduced intravenously into mice disappeared from the blood less than 24 h after inoculation and did not produce pyelonephritis. The same strain, 1 X 10(7) to 5 X 10(7) organisms, inoculated into the urinary bladder of mice was not rec...

journal_title：Infection and immunity

authors： Shimono E,Yanagawa R

更新日期：1977-04-01 00:00:00

abstract：:Interleukin-18 (IL-18) is a proinflammatory cytokine that plays an important role in natural killer cell activation and the T helper 1 (Th1) cell response, particularly in collaboration with IL-12. Since Th1 cells play a pivotal role in the host defense against infection with intracellular microbes, such as Leishmania...

journal_title：Infection and immunity

authors： Ohkusu K,Yoshimoto T,Takeda K,Ogura T,Kashiwamura S,Iwakura Y,Akira S,Okamura H,Nakanishi K

更新日期：2000-05-01 00:00:00

abstract：:Gamma interferon (IFN-gamma) is produced in response to circulating lipopolysaccharide (LPS) and contributes to the lethality of endotoxic shock. To address the cellular source of IFN-gamma production in vivo, T cells and B cells were magnetically purified from C57BL/6 mouse spleens 5 h following endotoxin injection. ...

journal_title：Infection and immunity

authors： Heinzel FP,Rerko RM,Ling P,Hakimi J,Schoenhaut DS

更新日期：1994-10-01 00:00:00

abstract：:Listeria monocytogenes is an intracellular bacterial pathogen that invades epithelial cells by subverting two cellular receptors, E-cadherin and Met. We recently identified type II phosphatidylinositol 4-kinases alpha and beta (PI4KIIalpha and PI4KIIbeta) as being required for bacterial entry downstream of Met. In thi...

journal_title：Infection and immunity

authors： Tham TN,Gouin E,Rubinstein E,Boucheix C,Cossart P,Pizarro-Cerda J

更新日期：2010-01-01 00:00:00

abstract：:Virulent Streptococcus suis serotype 2 strains are invasive extracellular bacteria causing septicemia and meningitis in piglets and humans. One objective of this study was to elucidate the function of complement in innate immune defense against S. suis. Experimental infection of wild-type (WT) and C3(-/-) mice demonst...

journal_title：Infection and immunity

authors： Seitz M,Beineke A,Singpiel A,Willenborg J,Dutow P,Goethe R,Valentin-Weigand P,Klos A,Baums CG

更新日期：2014-06-01 00:00:00

abstract：:PspA is an antigenically variable surface protein of Streptococcus pneumoniae that appears to be essential for full pneumococcal virulence. In addition, monoclonal antibodies to PspA protect mice against infection with specific strains of pneumococci virulent for mice. In this study, we have isolated the 43-kDa N-term...

journal_title：Infection and immunity

authors： Talkington DF,Crimmins DL,Voellinger DC,Yother J,Briles DE

更新日期：1991-04-01 00:00:00

abstract：:Production of interleukin-10 (IL-10) by C57BL/6 mice following infection with Borrelia burgdorferi has been proposed as a mechanism whereby resistance to the development of experimental Lyme arthritis is maintained. In the current study, we sought to determine the role of IL-10 during infection of arthritis- and cardi...

journal_title：Infection and immunity

authors： Brown CR,Lai AY,Callen ST,Blaho VA,Hughes JM,Mitchell WJ

更新日期：2008-12-01 00:00:00

abstract：:We examined the secretion of antimicrobial proteins and peptides into surgically isolated and continuously perfused segments of rat small intestine. Up to nine discrete antimicrobial molecules appeared in the intestinal perfusates following intravenous administration of bethanechol, a cholinergic agonist, or intralume...

journal_title：Infection and immunity

authors： Qu XD,Lloyd KC,Walsh JH,Lehrer RI

更新日期：1996-12-01 00:00:00

abstract：:Naturally occurring antibodies for Vibrio fetus with whole-cell and O antigen specificities were detected in sera of mature cattle by means of the agglutination and indirect immunofluorescence reactions. O antibodies occurred in each of 21 sera examined, and whole-cell antibodies, in lower concentrations, occurred in ...

journal_title：Infection and immunity

authors： Duncan JR,Wilkie BN,Winter AJ

更新日期：1972-05-01 00:00:00

abstract：:The adjuvant action of various lipopolysaccharides on immune responses to syngeneic tissue extract in mice was examined. Only lipopolysaccharides possessing the linear mannose homopolysaccharides as O-specific polysaccharides exhibited definite adjuvant action on immune responses to the autoantigens. The intensity of ...

journal_title：Infection and immunity

authors： Yokochi T,Fukada M,Kawai M,Zhang YH,Jiang GZ,Takahashi K

更新日期：1992-11-01 00:00:00

abstract：:Mycoplasma salivarium cells propagated in PPLO broth (Difco Laboratories, Detroit, Mich.) supplemented with rabbit serum (10% [vol/vol]) and harvested by centrifugation were shown to contain rabbit immunoglobulin G (IgG) (approximately 4 to 10% of total cell proteins) and to produce IgM autoantibodies to IgG when inoc...

journal_title：Infection and immunity

authors： Watanabe T,Shibata K,Hasegawa K

更新日期：1987-01-01 00:00:00

abstract：:In this study we found that serum inhibitory activity against Blastomyces dermatitidis was principally mediated by albumin. This was confirmed in experiments using albumin from several mammalian species. Analbuminemic rat serum did not inhibit B. dermatitidis growth in vivo; however, the addition of albumin restored i...

journal_title：Infection and immunity

authors： Giles S,Czuprynski C

更新日期：2003-11-01 00:00:00

abstract：:Depressed Th1 responses are a prominent feature of human tuberculosis, but an enhanced Th2 response has not been detected in peripheral blood T cells stimulated in vitro with Mycobacterium tuberculosis. In disease due to Mycobacterium leprae, Th2 cells predominate in tissue lesions of patients with extensive disease b...

journal_title：Infection and immunity

authors： Lin Y,Zhang M,Hofman FM,Gong J,Barnes PF

更新日期：1996-04-01 00:00:00

abstract：:Periodontitis is the inflammatory response in periodontal tissues elicited by bacterial colonization in periodontal pockets. In this response, pocket epithelial cells are the first cells to come into contact with bacteria. To elucidate this mechanism, we determined the adherence of the periodontopathic bacterium Eiken...

journal_title：Infection and immunity

authors： Yumoto H,Nakae H,Fujinaka K,Ebisu S,Matsuo T

更新日期：1999-01-01 00:00:00

abstract：:A significant clinical complication of pulmonary infections with Klebsiella pneumoniae is peripheral blood dissemination, resulting in a systemic infection concurrent with the localized pulmonary infection. In this context, little is known about the role of tumor necrosis factor receptor 1 (TNFR1)-mediated innate immu...

journal_title：Infection and immunity

authors： Moore TA,Perry ML,Getsoian AG,Monteleon CL,Cogen AL,Standiford TJ

更新日期：2003-09-01 00:00:00

abstract：:Attachment of Fusobacterium nucleatum to various oral surfaces is mediated by several adhesins anchored on its outer surface. Monoclonal antibodies (MAbs) were prepared and used to identify the putative galactose-binding adhesin of F. nucleatum PK1594. Four unique MAbs, 8G7, 26B9, 28G11, and 29D4, were isolated on the...

journal_title：Infection and immunity

authors： Shaniztki B,Hurwitz D,Smorodinsky N,Ganeshkumar N,Weiss EI

更新日期：1997-12-01 00:00:00

abstract：:Yersinia species pathogenic to humans have been extensively characterized with respect to type III secretion and its essential role in virulence. This study concerns the twin arginine translocation (Tat) pathway utilized by gram-negative bacteria to secrete folded proteins across the bacterial inner membrane into the ...

journal_title：Infection and immunity

authors： Lavander M,Ericsson SK,Bröms JE,Forsberg A

更新日期：2006-03-01 00:00:00

abstract：:Immunization with ribosomal preparations from Haemophilus influenzae type b elicited protective immunity in mice. Ribosomes from disrupted cells where isolated by differential centrifugation using sodium dodecyl sulfate. The washed ribosomes contained 25% protein and 75% ribonucleic acid and sedimented as a single pea...

journal_title：Infection and immunity

authors： Lynn M,Tewari RP,Solotorovsky M

更新日期：1977-02-01 00:00:00

abstract：:The coaggregation-defective (COG-) mutant Actinomyces viscosus T14V(PK455), which is unable to participate in lactose-sensitive adherence, and its COG+ parent were compared to structurally define the mutational loss of cell-associated lectin activity. Immunoelectrophoretic comparisons of crude extracts or isolated fim...

journal_title：Infection and immunity

authors： Cisar JO,Curl SH,Kolenbrander PE,Vatter AE

更新日期：1983-05-01 00:00:00

abstract：:Group A streptococci (GAS) are highly prevalent human pathogens whose primary ecological niche is the superficial epithelial layers of the throat and/or skin. Many GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus, genetic differences between them may c...

journal_title：Infection and immunity

authors： Rouchon CN,Ly AT,Noto JP,Luo F,Lizano S,Bessen DE

更新日期：2017-10-18 00:00:00

abstract：:A set of strain- and size-variant highly immunogenic membrane surface protein antigens of Mycoplasma bovis, which has been identified by a monoclonal antibody, is shown in this report to make up a family of antigenically and structurally related lipid-modified proteins, designated Vsps (variable surface proteins). By ...

journal_title：Infection and immunity

authors： Behrens A,Heller M,Kirchhoff H,Yogev D,Rosengarten R

更新日期：1994-11-01 00:00:00

abstract：:Humoral immunity does not play a prominent role during experimental cryptococcosis. However, previous studies have shown that immunoglobulin G (IgG) anti-Cryptococcus neoformans antibodies can mediate cell-dependent yeast killing in vitro. Therefore, the protective effect of a previously described monoclonal IgG1 anti...

journal_title：Infection and immunity

authors： Dromer F,Charreire J,Contrepois A,Carbon C,Yeni P

更新日期：1987-03-01 00:00:00

abstract：:The role of CD8 T cells in controlling Mycobacterium tuberculosis infections in mice was confirmed by comparing the levels of growth of the organism in control, major histocompatibility complex class II knockout, and athymic mice and by transferring T-cell populations into athymic mice. By using donor mice which were ...

journal_title：Infection and immunity

authors： Tascon RE,Stavropoulos E,Lukacs KV,Colston MJ

更新日期：1998-02-01 00:00:00

abstract：:Schistosomiasis affects nearly 40 million women of reproductive age. Many of these women are infected while pregnant and lactating. Several studies have demonstrated transplacental trafficking of schistosome antigens; however, little is known regarding how these antigens affect the developing fetus and placenta. To ev...

journal_title：Infection and immunity

authors： McDonald EA,Kurtis JD,Acosta L,Gundogan F,Sharma S,Pond-Tor S,Wu HW,Friedman JF

更新日期：2013-03-01 00:00:00

abstract：:The Staphylococcus aureus repeat (STAR) element is a sequence identified in two intergenic regions in S. aureus. The element is found in 13 to 21 copies in individual S. aureus strains, and elements in the homologous intergenic location are variable in length. The element sequence consists of several small and unusual...

journal_title：Infection and immunity

authors： Cramton SE,Schnell NF,Götz F,Brückner R

更新日期：2000-04-01 00:00:00

abstract：:Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9 (PfClag9) is a component of the PfClag9-R...

journal_title：Infection and immunity

authors： Chourasia BK,Deshmukh A,Kaur I,Paul G,Panda A,Rathore S,Singh SK,Theisen M,Mohmmed A,Malhotra P

更新日期：2020-01-22 00:00:00

abstract：:In order to approximate and adhere to mucosal epithelial cells, Candida must traverse the overlying mucus layer. Interactions of Candida species with mucin and human buccal epithelial cells (BECs) were thus investigated in vitro. Binding of the Candida species to purified small intestinal mucin showed a close correlat...

journal_title：Infection and immunity

authors： de Repentigny L,Aumont F,Bernard K,Belhumeur P

更新日期：2000-06-01 00:00:00

abstract：:Cells of Yersinia pestis strain EV76 are known to cease growth after a shift from 26 to 37 degrees C in neutral Ca2+-deficient medium; this effect is potentiated by Mg2+. With 2.5 mM Mg2+ and no added Ca2+, restriction was relaxed at elevated pH at which maximum cell yields occurred in the presence of 20 mM exogenous ...

journal_title：Infection and immunity

authors： Zahorchak RJ,Brubaker RR

更新日期：1982-12-01 00:00:00

abstract：:The chromosomal iroBCDEN gene cluster first described for Salmonella enterica is involved in the uptake of catecholate-type siderophore compounds. An orthologous gene cluster has recently been detected in Escherichia coli strains which cause extraintestinal disease. This E. coli iroBCDEN gene cluster has an impact on ...

journal_title：Infection and immunity

authors： Sorsa LJ,Dufke S,Heesemann J,Schubert S

更新日期：2003-06-01 00:00:00

abstract：:No studies to date clearly define the interactions between Porphyromonas gingivalis and human peripheral blood polymorphonuclear leukocytes (PMN), nor has a protective role for antibody to P. gingivalis been defined. Using a fluorochrome phagocytosis microassay, we investigated PMN phagocytosis and killing of P. gingi...

journal_title：Infection and immunity

authors： Cutler CW,Kalmar JR,Arnold RR

更新日期：1991-06-01 00:00:00