Identification of a Fusobacterium nucleatum PK1594 galactose-binding adhesin which mediates coaggregation with periopathogenic bacteria and hemagglutination.

abstract：:A key function of monocytes/macrophages (Mphi) is to present antigens to T cells. However, upon interaction with bacteria, Mphi lose their ability to effectively present soluble antigens. This functional loss was associated with alterations in the expression of adhesion molecules and CD14 and a reduction in the uptake...

journal_title：Infection and immunity

authors： Wyant TL,Tanner MK,Sztein MB

更新日期：1999-03-01 00:00:00

abstract：:The antigenically conserved proteins of Treponema pallidum subsp. pallidum and four nonpathogenic cultivatable treponemes were investigated by phase partitioning with the nonionic detergent Triton X-114 and immunoblot analysis. None of the T. pallidum integral membrane proteins identified by phase partitioning (deterg...

journal_title：Infection and immunity

authors： Radolf JD,Norgard MV

更新日期：1988-07-01 00:00:00

abstract：:The phenotypic and functional changes of glycolipid presented by CD1d(glycolipid/CD1d) specific Valpha14+ T cells in the liver of mice at early stages of bacterial infection were investigated. After Listeria monocytogenes infection or interleukin-12 (IL-12) treatment, alpha-galactosylceramide/CD1d tetramer-reactive (a...

journal_title：Infection and immunity

authors： Emoto M,Yoshizawa I,Emoto Y,Miamoto M,Hurwitz R,Kaufmann SH

更新日期：2006-10-01 00:00:00

abstract：:The Leishmania pifanoi amastigote antigen P-8 has been previously shown to induce protective immunity in a murine model of cutaneous leishmaniasis (L. Soong, S. M. Duboise, P. Kima, and D. McMahon-Pratt, Infect. Immun. 63:3559-3566, 1995). As this antigen is of interest for further vaccine studies, the biochemical cha...

journal_title：Infection and immunity

authors： Colmenares M,Tiemeyer M,Kima P,McMahon-Pratt D

更新日期：2001-11-01 00:00:00

abstract：:Kinetoplastid membrane protein 11 (KMP-11) from Leishmania donovani is an abundant 11-kDa surface membrane glycoprotein. Lymph node cells from mice of six different H-2 haplotypes immunized with KMP-11 or with L. donovani promastigotes were stimulated to proliferate in vitro KMP-11. Primed purified T cells required an...

journal_title：Infection and immunity

authors： Tolson DL,Jardim A,Schnur LF,Stebeck C,Tuckey C,Beecroft RP,Teh HS,Olafson RW,Pearson TW

更新日期：1994-11-01 00:00:00

abstract：:Pneumonia due to Gram-negative bacteria is associated with high mortality. Acinetobacter baumannii is a Gram-negative bacterium that is associated with hospital-acquired and ventilator-associated pneumonia. Bacteria have been described to release outer membrane vesicles (OMVs) that are capable of mediating systemic in...

journal_title：Infection and immunity

authors： Marion CR,Lee J,Sharma L,Park KS,Lee C,Liu W,Liu P,Feng J,Gho YS,Dela Cruz CS

更新日期：2019-08-21 00:00:00

abstract：:The extracellular cysteine protease from Streptococcus pyogenes is a virulence factor that plays a significant role in host-pathogen interaction. Streptococcal protease is expressed as an inactive 40-kDa precursor that is autocatalytically converted into a 28-kDa mature (active) enzyme. Replacement of the single cyste...

journal_title：Infection and immunity

authors： Matsuka YV,Pillai S,Gubba S,Musser JM,Olmsted SB

更新日期：1999-09-01 00:00:00

abstract：:The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) through pattern recognition receptors (PRR) and transduces downstream signaling to activate the host defense. Here we report that in addition to direct PAMP-PRR interactions, live Candida albicans cells can release soluble factors to ac...

journal_title：Infection and immunity

authors： Cheng SC,Chai LY,Joosten LA,Vecchiarelli A,Hube B,Van Der Meer JW,Kullberg BJ,Netea MG

更新日期：2010-01-01 00:00:00

abstract：:Antigen 2 (Ag2), a major immunoreactive component of Coccidioides immitis mycelium- and spherule-phase cell walls, was recently cloned in our laboratory and was shown to elicit T-cell responses in Coccidioides-immune mice. In this investigation, we evaluated recombinant Ag2 (rAg2) and PCR-generated Ag2 truncations for...

journal_title：Infection and immunity

authors： Zhu Y,Tryon V,Magee DM,Cox RA

更新日期：1997-08-01 00:00:00

abstract：:Randomly bred guinea pigs were infected with Listeria monocytogenes using the intracardial, intravenous and intraperitoneal routes of infection. Doses of Listeria ranged from 5 to 1,000 x the 50% lethal dose based on the 50% lethal dose for intracardially injected Listeria. A complete necropsy was performed on all ani...

journal_title：Infection and immunity

authors： Dustoor M,Croft W,Fulton A,Blazkovec A

更新日期：1977-03-01 00:00:00

abstract：:A ruthenium red-staining capsule was observed on two pathogenic strains, but not on one nonpathogenic strain of Mycoplasma gallisepticum. The capsule appeared to mediate cytadsorption of mycoplasmas to the chicken tracheal epithelium without evidence of membrane fusion. No relationship was seen between the presence of...

journal_title：Infection and immunity

authors： Tajima M,Yagihashi T,Miki Y

更新日期：1982-05-01 00:00:00

abstract：:Dialyzable Lawrence-type transfer factor was prepared from the spleen cells of CF1 mice inoculated with Coccidioides immitis- and Candida albicans-killed vaccines and with live Mycobacterium tuberculosis vaccine (BCG). These preparations were shown to transfer antigen-specific cell-mediated immunity to naive mice, as ...

journal_title：Infection and immunity

authors： Rifkind D,Frey JA,Petersen EA,Dinowitz M

更新日期：1977-04-01 00:00:00

abstract：:Chromosomes from Cryptococcus neoformans, an encapsulated yeast pathogen, were separated by contour-clamped homogeneous field gel electrophoresis. Seven strains representing all four serotypes were studied. It was found that each strain had a unique, reproducible pattern of chromosome bands which could potentially be ...

journal_title：Infection and immunity

authors： Perfect JR,Magee BB,Magee PT

更新日期：1989-09-01 00:00:00

abstract：:In this study, a novel recombinant attenuated Yersinia pseudotuberculosis PB1+ strain (χ10069) engineered with ΔyopK ΔyopJ Δasd triple mutations was used to deliver a Y. pestis fusion protein, YopE amino acid 1 to 138-LcrV (YopENt138-LcrV), to Swiss Webster mice as a protective antigen against infections by yersiniae....

journal_title：Infection and immunity

authors： Singh AK,Curtiss R 3rd,Sun W

更新日期：2019-09-19 00:00:00

abstract：:The salmonid macrophage-like cell line RTS-11 and purified trout pronephros phagocytes were used to analyze in vitro entry and survival of two Streptococcus iniae serotypes. Efficient invasion by S. iniae occurred in both cells, but only the type II strain persisted in pronephros phagocytes for at least 48 h. Ex vivo ...

journal_title：Infection and immunity

authors： Zlotkin A,Chilmonczyk S,Eyngor M,Hurvitz A,Ghittino C,Eldar A

更新日期：2003-05-01 00:00:00

abstract：:Resistance against acute and chronic infection with Taxoplasma gondii in BALB/c and CBA/Ca mice was compared. Intraperitoneal inoculation of either 20, 40, or 80 cysts of the ME49 strain resulted in mortality rates in BALB/c mice of 12% (2 of 17), 50% (6 of 12), and 75% (9 of 12), respectively, within 3 weeks after in...

journal_title：Infection and immunity

authors： Suzuki Y,Orellana MA,Wong SY,Conley FK,Remington JS

更新日期：1993-06-01 00:00:00

abstract：:Actinlike material was obtained from disrupted Pseudomonas aeruginosa cells by a modification of the method of Hancock and Nikaido (J. Bacteriol. 136:381-390) for isolating outer membrane vesicles. Pelleted membranes were dissolved in Laemmli sample buffer and electrophoresed in parallel lanes with purified rabbit ske...

journal_title：Infection and immunity

authors： Berk RS,Moon M,Higbee R,Cramer C,Roher A,Weis M,Hazlett L

更新日期：1985-11-01 00:00:00

abstract：:Eight chlamydial isolates of ovine origin were tested in a plaque reduction system using homologous and heterologous rooster antisera. The eight isolates could be separated into two separate immunotypes. Type 1 included isolates associated with ovine abortion and one agent recovered from the feces of an apparently nor...

journal_title：Infection and immunity

authors： Schachter J,Banks J,Sugg N,Sung M,Storz J,Meyer KF

更新日期：1974-01-01 00:00:00

abstract：:Ambient pH signaling involves a cascade of conserved Rim or Pal products in ascomycetous yeasts or filamentous fungi, respectively. Recent evidences in the fungi Aspergillus nidulans, Saccharomyces cerevisiae, Yarrowia lipolytica, and Candida albicans suggested that components of endosomal sorting complexes required f...

journal_title：Infection and immunity

authors： Cornet M,Bidard F,Schwarz P,Da Costa G,Blanchin-Roland S,Dromer F,Gaillardin C

更新日期：2005-12-01 00:00:00

abstract：:Streptococcal pyrogenic exotoxin B (SpeB), a conserved cysteine protease expressed by virtually all Streptococcus pyogenes strains, has recently been shown to be an important virulence factor (S. Lukomski, S. Sreevatsan, C. Amberg, W. Reichardt, M. Woischnik, A. Podbielski, and J. M. Musser, J. Clin. Invest. 99:2574-2...

journal_title：Infection and immunity

authors： Lukomski S,Burns EH Jr,Wyde PR,Podbielski A,Rurangirwa J,Moore-Poveda DK,Musser JM

更新日期：1998-02-01 00:00:00

abstract：:Neutrophils are the first cells to infiltrate to the site of Leishmania promastigote infection, and these cells help to reduce parasite burden shortly after infection is initiated. Several clinical reports indicate that neutrophil recruitment is sustained over the course of leishmaniasis, and amastigote-laden neutroph...

journal_title：Infection and immunity

authors： Carlsen ED,Hay C,Henard CA,Popov V,Garg NJ,Soong L

更新日期：2013-11-01 00:00:00

abstract：:Mice immunized with infections of 500, 5,000, or 20,000 oocysts of E. falciformis var. pragensis were reinfected with 20,000 and 100,000 oocysts at 20 and 38 days, respectively, after the initial infection. After the first challenge infection, none of the immunized mice showed clinical signs of coccidiosis; a few mice...

journal_title：Infection and immunity

authors： Mesfin GM,Bellamy JE

更新日期：1979-01-01 00:00:00

abstract：:Fusobacterium nucleatum is closely associated with human periodontal diseases and may also be a causative agent in other infections, such as pericarditis, septic arthritis, and abscesses of tonsils and liver. Initiation and outcome of infective diseases depend critically on the host cell signaling system altered by th...

journal_title：Infection and immunity

authors： Uitto VJ,Baillie D,Wu Q,Gendron R,Grenier D,Putnins EE,Kanervo A,Firth JD

更新日期：2005-02-01 00:00:00

abstract：:Staphylococcal enterotoxins A through D (SEA through SED) and toxic shock syndrome toxin-1 display superantigen properties, i.e., they stimulate a great fraction of T cells expressing certain T-cell receptor V beta sequences. Using a newly established rat model of septic Staphylococcus aureus arthritis, we have recent...

journal_title：Infection and immunity

authors： Bremell T,Tarkowski A

更新日期：1995-10-01 00:00:00

abstract：:The kinetics of cytotoxic T lymphocyte antigen 4 (CTLA-4) expression on T cells responding to Cryptococcus neoformans and its role in regulating the T-cell response were examined. Using peripheral blood mononuclear cells stimulated with encapsulated or acapsular C. neoformans we showed that (i) the encapsulated strain...

journal_title：Infection and immunity

authors： Pietrella D,Perito S,Bistoni F,Vecchiarelli A

更新日期：2001-03-01 00:00:00

abstract：:Microbial heat shock proteins (HSP) are dominant antigens for the host immune response. Because of the high sequence homology between mammalian and microbial HSP, their value as component of a subunit vaccine has been the subject of controversy. Previous work from this laboratory, however, demonstrated for the first t...

journal_title：Infection and immunity

authors： Noll A,AutenriethIB

更新日期：1996-08-01 00:00:00

abstract：:Cell surface protein SSP-5 in the oral bacterium Streptococcus gordonii M5 binds human salivary agglutinin in a Ca(2+)-dependent reaction (D.R. Demuth, E.E. Golub, and D. Malamud, J. Biol. Chem. 265:7120-7126, 1990). The region of the gene encoding an N-terminal segment of a related polypeptide (SspA) in S. gordonii D...

journal_title：Infection and immunity

authors： Jenkinson HF,Terry SD,McNab R,Tannock GW

更新日期：1993-08-01 00:00:00

abstract：:The immune response to the mycobacterial 65-kDa heat shock protein (hsp65) is considered an important event in the induction of adjuvant arthritis (AA) in rats; this induction probably occurs through a molecular mimicry mechanism involving cross-reactivity against the rat homolog hsp60. To analyze the role of mammalia...

journal_title：Infection and immunity

authors： López-Guerrero JA,López-Bote JP,Ortiz MA,Gupta RS,Páez E,Bernabeu C

更新日期：1993-10-01 00:00:00

abstract：:Peritoneal exudate cells from chickens immunized with two species of coccidia, Eimeria tenella or Eimeria maxima, were examined for their capacity to phagocytose stages of the parasite in vitro. True phagocytosis of the sporozoite stage is difficult to estimate because of its ability to invade cells, but may be evalua...

journal_title：Infection and immunity

authors： Rose ME

更新日期：1974-10-01 00:00:00

abstract：:Mice (BALB/cJ, C3H/HeN, and C3H/HeJ) primed with actinomycin D became highly susceptible to lethal intoxication with staphylococcal enterotoxin B (SEB). The mice underwent toxicosis and toxic shock and died. Actinomycin D-primed C3H/HeN and C3H/HeJ mice showed equal sensitivity to SEB, suggesting that bacterial lipopo...

journal_title：Infection and immunity

authors： Chen JY,Qiao Y,Komisar JL,Baze WB,Hsu IC,Tseng J

更新日期：1994-10-01 00:00:00