Abstract:
:Eight chlamydial isolates of ovine origin were tested in a plaque reduction system using homologous and heterologous rooster antisera. The eight isolates could be separated into two separate immunotypes. Type 1 included isolates associated with ovine abortion and one agent recovered from the feces of an apparently normal sheep. Type 2 isolates were associated with polyarthritis and conjunctivitis. These two serotypes were not cross-reactive with several chlamydiae of avian origin. Further application of the plaque reduction test may provide a useful means of typing chlamydiae.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Schachter J,Banks J,Sugg N,Sung M,Storz J,Meyer KFdoi
10.1128/IAI.9.1.92-94.1974subject
Has Abstractpub_date
1974-01-01 00:00:00pages
92-4issue
1eissn
0019-9567issn
1098-5522journal_volume
9pub_type
杂志文章abstract::γ9δ2 T cells provide a natural bridge between innate and adaptive immunity, rapidly and potently respond to pathogen infection in mucosal tissues, and are prominently induced by both tuberculosis (TB) infection and bacillus Calmette Guérin (BCG) vaccination. Mycobacterium-expanded γ9δ2 T cells represent only a subset ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01322-15
更新日期:2016-08-19 00:00:00
abstract::Strains of indigenous Escherichia coli, Bacteroides, and Lactobacillus were isolated from the gastrointestinal tracts of specific pathogen-free (SPF) mice. Nonvaccinated SPF mice exhibited in their spleens low numbers of plaque-forming cells (PFC) and rosette-forming cells reacting with antigens of these andigenous ba...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.11.2.320-329.1975
更新日期:1975-02-01 00:00:00
abstract::To ascertain the effects of selective impairment of the fixed macrophage compartment on host defense, rabbit anti-rat Kupffer cell serum was raised and tested for its ability to depress phagocytosis and to serve as an immunosuppressant. The ability of the anti-Kupffer cell serum (AKS) to depress intravascular clearanc...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.2.4.448-452.1970
更新日期:1970-10-01 00:00:00
abstract::Streptococcal protective antigen (Spa) is a newly described surface protein of group A streptococci that was recently shown to evoke protective antibodies (J. B. Dale, E. Y. Chiang, S. Liu, H. S. Courtney, and D. L. Hasty, J. Clin. Investig. 103:1261--1268, 1999). In this study, we have determined the complete sequenc...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.69.5.2943-2949.2001
更新日期:2001-05-01 00:00:00
abstract::Serologic parameters of kala-azar were evaluated by Western blot analysis. Sera from kala-azar patients with confirmed diagnoses were screened for immunoglobulin G (IgG) and IgG subclass-specific reactivity against Leishmania donovani membrane antigen (LAg). Heterogeneous LAg-specific IgG reactivity with numerous prot...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.72.2.863-870.2004
更新日期:2004-02-01 00:00:00
abstract::The antigenically conserved proteins of Treponema pallidum subsp. pallidum and four nonpathogenic cultivatable treponemes were investigated by phase partitioning with the nonionic detergent Triton X-114 and immunoblot analysis. None of the T. pallidum integral membrane proteins identified by phase partitioning (deterg...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.56.7.1825-1828.1988
更新日期:1988-07-01 00:00:00
abstract::Cells of Candida albicans strain WO-1 and related strains switch frequently and reversibly between a white-colony-forming unit (white phase) and a gray-colony-forming unit (opaque phase). Cells in the budding white phase exhibit the usual smooth round phenotype observed in other C. albicans strains, but cells in the b...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.57.2.458-467.1989
更新日期:1989-02-01 00:00:00
abstract::We have studied the ability of outer membrane vesicle (OMV) vaccines from Neisseria meningitidis serogroup B to induce vaccine-specific antibody and spleen cell proliferative responses in mice after being administered intranasally (i.n.) and/or subcutaneously (s.c.). A series of four weekly i.n. doses (25 microg) with...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.69.8.5010-5015.2001
更新日期:2001-08-01 00:00:00
abstract::The relative immunogenicities of three forms of the Escherichia coli heatlabile enterotoxin (LT), the holotoxin, its B subunit, and the polymyxin-release form (PM LT) were compared by immunizing rats with various dosages of each given exclusively by the parenteral (IP/IP) or peroral (PO/PO) routes or by a combination ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.31.1.144-150.1981
更新日期:1981-01-01 00:00:00
abstract::Malaria infection caused by Plasmodium parasites continues to cause enormous morbidity and mortality in areas where it is endemic, and there is no licensed vaccine capable of inducing sterile protection. Hyperimmunization with attenuated whole sporozoites can induce sterile protective immune responses targeting preery...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01439-15
更新日期:2016-07-21 00:00:00
abstract::Pulmonary washings from rabbits were freed of cells and added to the monolayers of homologous alveolar macrophages (AM). At 1 h after incubation with the pulmonary washings, many more cells adhered to glass, spread out, and showed enhanced Nitro Blue Tetrazolium reduction. The maximal effect of the pulmonary washings ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.20.2.476-484.1978
更新日期:1978-05-01 00:00:00
abstract::Ehrlichia chaffeensis and Anaplasma phagocytophilum are agents of human monocytic and granulocytic ehrlichioses, respectively. They are extremely sensitive to mechanical stress and are pleomorphic gram-negative bacteria. Membrane incorporation of cholesterol from the eukaryotic host is known to be essential for other ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.9.5324-5331.2003
更新日期:2003-09-01 00:00:00
abstract::Pneumocystis pneumonia (PcP) is a life-threatening infection that affects immunocompromised individuals. Nearly half of all PcP cases occur in those prescribed effective chemoprophylaxis, suggesting that additional preventive methods are needed. To this end, we have identified a unique mouse Pneumocystis surface prote...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00850-16
更新日期:2017-03-23 00:00:00
abstract::The urease gene cluster from the virulent Actinobacillus pleuropneumoniae serotype 1 strain CM5 was cloned and sequenced. The urease activity was associated with a 6.3-kbp region which contains eight long open reading frames (ORFs). The structural genes, ureABC, are separated from the accessory genes, ureEFGD, by a 61...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.65.11.4389-4394.1997
更新日期:1997-11-01 00:00:00
abstract::Cell surface proteins SspA and SspB in Streptococcus gordonii and SpaP in Streptococcus mutans are members of the antigen I/II family of polypeptides produced by oral streptococci. These proteins are adhesins and mediate species-specific binding of cells to a variety of host and bacterial receptors. Here we show that ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.65.12.5157-5164.1997
更新日期:1997-12-01 00:00:00
abstract::To elucidate the mechanism of the high incidence of lower respiratory tract infections in patients with diabetes mellitus, we investigated the kinetics of production of macrophage inflammatory protein 2 (MIP-2), an important mediator of lung neutrophil recruitment, using mice with streptozotocin-induced diabetes. Intr...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.68.5.2925-2929.2000
更新日期:2000-05-01 00:00:00
abstract::Since secondary Streptococcus pneumoniae infections greatly increase the mortality of influenza infections, we determined the relative roles of neutrophil-dependent and -independent mechanisms in increased susceptibility to S. pneumoniae during influenza infection. Mice infected with influenza for 6 days, but not 3 da...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00789-06
更新日期:2006-12-01 00:00:00
abstract::Tuberculosis continues to ravage humanity, killing 2 million people yearly. Most cases occur in areas of the world to which the disease is endemic, where almost everyone is vaccinated early in life with Mycobacterium bovis BCG, the currently available vaccine against tuberculosis. Thus, while more-potent vaccines are ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.8.4676-4683.2005
更新日期:2005-08-01 00:00:00
abstract::Streptococcus mutans, a major pathogen of dental caries, is considered one of the causative agents of infective endocarditis (IE). Recently, bacterial DNA encoding 120-kDa cell surface collagen-binding proteins (CBPs) has frequently been detected from S. mutans-positive IE patients. In addition, some of the CBP-positi...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00401-17
更新日期:2017-11-17 00:00:00
abstract::Chromatin modification triggered by bacteria is a newly described mechanism by which pathogens impact host transcription. Listeria monocytogenes dephosphorylates histone H3 through the action of listeriolysin O (LLO); however, the underlying mechanism is unknown. Here we show that an unrelated pore-forming toxin, Aero...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01243-10
更新日期:2011-07-01 00:00:00
abstract::The ability of a pathogen to evade neutrophil phagocytic killing mechanisms is critically important for dissemination and establishment of a systemic infection. Understanding how pathogens overcome these innate defenses is essential for the development of optimal therapeutic strategies for invasive infections. CpsY is...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00027-12
更新日期:2012-05-01 00:00:00
abstract::Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity. We provide here the first description o...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.02141-14
更新日期:2014-09-01 00:00:00
abstract::Extracts of specific granules and azurophil granules from human neutrophils were tested for their bactericidal activity against various lipopolysaccharide mutants of Salmonella typhimurium LT-2. Three purified granule populations, one specific and two azurophil, were obtained by isopycnic centrifugation of homogenized...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.19.1.131-137.1978
更新日期:1978-01-01 00:00:00
abstract::Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In th...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.72.12.7322-7325.2004
更新日期:2004-12-01 00:00:00
abstract::Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.16.2.715-716.1977
更新日期:1977-05-01 00:00:00
abstract::Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver lobules during the early phase, and LPS in the late phase caused death in association with pathological changes mimicking he...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.63.12.4812-4817.1995
更新日期:1995-12-01 00:00:00
abstract::Previous studies have demonstrated that animals exposed to Streptococcus pneumoniae while recovering from influenza A virus infection exhibit exacerbated disease symptoms. However, many of the current animal models exploring dual viral and bacterial synergistic exacerbations of respiratory disease have utilized mouse-...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01943-06
更新日期:2007-06-01 00:00:00
abstract::Contributions of the alternative sigma factor sigmaB to Listeria monocytogenes infection were investigated using strains bearing null mutations in sigB, prfA, or inlA or in selected inlA or prfA promoter regions. The DeltaP4inlA strain, which has a deletion in the sigmaB-dependent P4inlA promoter, and the DeltasigB st...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.74.2.876-886.2006
更新日期:2006-02-01 00:00:00
abstract::Secretion of immunoglobulin A1 (IgA1) proteases is a characteristic of Haemophilus influenzae and several other bacterial pathogens causing infectious diseases, including meningitis. Indirect evidence suggests that the proteases are important virulence factors. In this study, we cloned the iga gene encoding immunoglob...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.57.10.3097-3105.1989
更新日期:1989-10-01 00:00:00
abstract::One of the chromosomal segments associated with the virulence of Shigella flexneri and transferred to Escherichia coli K-12 by conjugation has been shown to code for the production of aerobactin and for the synthesis of an iron-regulated 76,000-dalton (76K) outer membrane protein. Analysis of various E. coli K-12-S. f...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.49.1.67-71.1985
更新日期:1985-07-01 00:00:00