Activation of alveolar macrophages exposed to lavage-procured immunoglobulin G obtained from normal rabbit lungs.

abstract：:Four monoclonal antibodies (MAbs) were produced by immunizing mice with a disrupted yeast cell homogenate of Histoplasma capsulatum. MAbs 1 and 2 reacted only with the yeast cell antigens of H. capsulatum and Blastomyces dermatitidis, whereas MAbs 3 and 4 showed broader cross-reactivity. MAb 3 cross-reacted with B. de...

journal_title：Infection and immunity

authors： Kamel SM,Wheat LJ,Garten ML,Bartlett MS,Tansey MR,Tewari RP

更新日期：1989-03-01 00:00:00

abstract：:Rabbit lymphoid cells from spleen, peripheral blood, and peritoneal cavity lacked killer (K)-cell activity against cell lines of rabbit and human origin, including virus-infected human tumor cells. This lack of activity was not affected by antibody concentration, source of antibodies, effector/target cell ratio, or le...

journal_title：Infection and immunity

authors： Karavodin LM,Sidell N,Woan MC,Tompkins WA

更新日期：1982-02-01 00:00:00

abstract：:Vibrio parahaemolyticus is a gram-negative marine bacterium. A limited population of the organisms causes acute gastroenteritis in humans. Almost all of the clinical V. parahaemolyticus isolates exhibit beta-type hemolysis on Wagatsuma agar, known as the Kanagawa phenomenon (KP). KP is induced by the thermostable dire...

journal_title：Infection and immunity

authors： Izutsu K,Kurokawa K,Tashiro K,Kuhara S,Hayashi T,Honda T,Iida T

更新日期：2008-03-01 00:00:00

abstract：:C4BP (C4b-binding protein) is a high-molecular-weight plasma protein that inhibits the classical pathway of complement activation. Recent experiments have demonstrated that C4BP binds to many strains of the gram-positive bacterium Streptococcus pyogenes, a major respiratory tract pathogen. Binding to S. pyogenes was s...

journal_title：Infection and immunity

authors： Berggård K,Johnsson E,Mooi FR,Lindahl G

更新日期：1997-09-01 00:00:00

abstract：:The effect of respiratory syncytial virus (RSV) or mixtures of RSV and its specific antibody on the oxidative metabolic activity of human polymorphonuclear leukocytes was studied by the technique of luminol-dependent chemiluminescence. Peripheral blood neutrophils obtained from normal healthy donors were used. RSV alo...

journal_title：Infection and immunity

authors： Kaul TN,Faden H,Ogra PL

更新日期：1981-05-01 00:00:00

abstract：:The antiphagocytic effect of the Staphylococcus aureus capsule is known to be related to its ability to interfere with opsonization by normal human serum. In this study, evidence is presented with isolated cell surface components which indicates that the capsule hinders opsonization by masking cell wall peptidoglycan....

journal_title：Infection and immunity

authors： Wilkinson BJ,Peterson PK,Quie PG

更新日期：1979-02-01 00:00:00

abstract：:Bordetella pertussis is the causative agent of whooping cough, a potentially lethal respiratory disease in children. In immunocompetent individuals, B. pertussis infection elicits an effective adaptive immune response driven by activated CD4(+) T cells. However, live B. pertussis persists in the host for 3 to 4 weeks ...

journal_title：Infection and immunity

authors： Shumilla JA,Lacaille V,Hornell TM,Huang J,Narasimhan S,Relman DA,Mellins ED

更新日期：2004-03-01 00:00:00

abstract：:Recent preclinical and epidemiologic studies have suggested that certain Mycobacterium tuberculosis genotypes (in particular, Beijing lineage strains) may be resistant to Mycobacterium bovis BCG vaccine-induced antituberculosis protective immunity. To investigate the strain specificity of BCG-induced protective respon...

journal_title：Infection and immunity

authors： Jeon BY,Derrick SC,Lim J,Kolibab K,Dheenadhayalan V,Yang AL,Kreiswirth B,Morris SL

更新日期：2008-11-01 00:00:00

abstract：:Heat shock protein (HSP) expression was examined in murine bone marrow-derived macrophages infected with stationary-phase promastigotes of Leishmania donovani. Immunoblotting performed with a rabbit polyclonal antiserum raised against HSP60 from Heliothis virescens (moth) revealed the de novo appearance of 65- and 67-...

journal_title：Infection and immunity

authors： Rey-Ladino JA,Reiner NE

更新日期：1993-08-01 00:00:00

abstract：:The role of glycosylinositol phospholipid 1 (GIPL-1) of Leishmania (Leishmania) major in the interaction of promastigotes and amastigotes with macrophages was analyzed. Monoclonal antibody MEST-1, which recognizes glycolipids containing terminal galactofuranose (Galf) residues (E. Suzuki, M. S. Toledo, H. K. Takahashi...

journal_title：Infection and immunity

authors： Suzuki E,Tanaka AK,Toledo MS,Takahashi HK,Straus AH

更新日期：2002-12-01 00:00:00

abstract：:We found that oral immunization with flagellum-defective mutant strains of Salmonella enterica serovar Typhimurium with the ClpXP-deficient background protected mice against oral challenge with the virulent strain. These data indicate that Salmonella flagellin is not a dominant protective antigen in oral immunization ...

journal_title：Infection and immunity

authors： Kodama C,Matsui H

更新日期：2004-04-01 00:00:00

abstract：:A major problem in the study of chlamydial genital infections in animal models has been the use of varied doses of chlamydiae for infection in different laboratories. It is clearly desirable to use a dose which approximates that of natural sexual infection, but that dose to date has not been determined because of the ...

journal_title：Infection and immunity

authors： Rank RG,Bowlin AK,Reed RL,Darville T

更新日期：2003-11-01 00:00:00

abstract：:Lactoferrin (LF) is a multifunctional immunoregulatory protein that has been associated with host defense at mucosal surfaces through its antibacterial properties. The antibacterial and anti-inflammatory properties of LF were further explored with an animal model of experimental urinary tract infection. Bovine LF (bLF...

journal_title：Infection and immunity

authors： Håversen LA,Engberg I,Baltzer L,Dolphin G,Hanson LA,Mattsby-Baltzer I

更新日期：2000-10-01 00:00:00

abstract：:The interaction of purified human fibrinogen with Aspergillus fumigatus conidia was investigated by immunofluorescence and electron microscopy and binding assays with radiolabeled proteins. We described the localization of the binding sites on the A. fumigatus conidia and on the fibrinogen molecule and determined the ...

journal_title：Infection and immunity

authors： Annaix V,Bouchara JP,Larcher G,Chabasse D,Tronchin G

更新日期：1992-05-01 00:00:00

abstract：:Vibrio cholerae, the pathogen that causes cholera, also survives in aqueous reservoirs, probably in the form of biofilms. Quorum sensing negatively regulates V. cholerae biofilm formation through HapR, whose expression is induced at a high cell density. In this study, we show that the concentration of the quorum-sensi...

journal_title：Infection and immunity

authors： Liu Z,Stirling FR,Zhu J

更新日期：2007-01-01 00:00:00

abstract：:Cryptococcus neoformans is surrounded by a capsular polysaccharide. There are at least four known serotypes of the polysaccharide. The objective of this study was to produce monoclonal antibodies (MAbs) that could be used to study the distribution of epitopes among the serotypes of C. neoformans. BALB/c mice were immu...

journal_title：Infection and immunity

authors： Eckert TF,Kozel TR

更新日期：1987-08-01 00:00:00

abstract：:Hepatitis, proliferative typhlitis, and colitis were characterized in young adult and older SCID/NCr mice naturally infected with Helicobacter hepaticus. Liver lesions consisted of Kupffer, Ito, and oval cell hyperplasia along with multifocal to coalescing coagulative hepatocyte necrosis. Numerous Warthin-Starry-posit...

journal_title：Infection and immunity

authors： Li X,Fox JG,Whary MT,Yan L,Shames B,Zhao Z

更新日期：1998-11-01 00:00:00

abstract：:Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL), SylvioX10/4 (SYL), and a cultured clone (TCC) exhibited differe...

journal_title：Infection and immunity

authors： Zago MP,Hosakote YM,Koo SJ,Dhiman M,Piñeyro MD,Parodi-Talice A,Basombrio MA,Robello C,Garg NJ

更新日期：2016-05-24 00:00:00

abstract：:In a cross-sectional survey of 187 Gambian children and adults, we have analyzed prevalence, fine specificity, and 19-kilodalton merozoite surface protein 1 (MSP-1(19))-specific erythrocyte invasion inhibitory activity of antibodies to MSP-1(19) but find no significant association between any of these parameters and p...

journal_title：Infection and immunity

authors： Corran PH,O'Donnell RA,Todd J,Uthaipibull C,Holder AA,Crabb BS,Riley EM

更新日期：2004-10-01 00:00:00

abstract：:Histophilus somni is capable of intracellular survival within professional phagocytic cells, but the mechanism of survival is not understood. The Fic motif within the direct repeat (DR1)/DR2 domains of the IbpA fibrillary network protein of H. somni is cytotoxic to epithelial and phagocytic cells, which may interfere ...

journal_title：Infection and immunity

authors： Pan Y,Tagawa Y,Champion A,Sandal I,Inzana TJ

更新日期：2018-11-20 00:00:00

abstract：:The major outer membrane protein (P2) of Haemophilus influenzae type b (Hib) with an apparent molecular weight of 37,000 to 40,000 has been previously shown to function as a porin and also as a target for antibodies protective against experimental Hib disease. The gene encoding the Hib P2 protein was cloned by using a...

journal_title：Infection and immunity

authors： Hansen EJ,Gonzales FR,Chamberlain NR,Norgard MV,Miller EE,Cope LD,Pelzel SE,Gaddy B,Clausell A

更新日期：1988-10-01 00:00:00

abstract：:Toll-like receptors (TLRs) are a major component of the pattern recognition receptor repertoire that detect invading microorganisms and direct the vertebrate immune system to eliminate infection. In chickens, the differential biology of Salmonella serovars (systemic versus gut-restricted localization) correlates with ...

journal_title：Infection and immunity

authors： Iqbal M,Philbin VJ,Withanage GS,Wigley P,Beal RK,Goodchild MJ,Barrow P,McConnell I,Maskell DJ,Young J,Bumstead N,Boyd Y,Smith AL

更新日期：2005-04-01 00:00:00

abstract：:Genetically based natural resistance to brucellosis in cattle provides for novel strategies to control zoonotic diseases. Bovine NRAMP1, the homologue of a murine gene (Bcg), has been identified as a major candidate for controlling the in vivo resistant phenotype. We developed an in vitro model for expression of resis...

journal_title：Infection and immunity

authors： Barthel R,Feng J,Piedrahita JA,McMurray DN,Templeton JW,Adams LG

更新日期：2001-05-01 00:00:00

abstract：:Evidence is presented that the chronicity of infection in CBA mice after injection of Brucella abortus 19 is related to a number of factors: (i) the relative resistance of B. abortus to macrophage killing, which allowed some bacteria to survive the peak of macrophage activity occurring at 14 days; (ii) the decline in ...

journal_title：Infection and immunity

authors： Cheers C,Pagram F

更新日期：1979-02-01 00:00:00

abstract：:Sepsis is both a common and, despite present-day therapy, a serious disease. The pathophysiology of the septic response is a complex, multifactorial phenomenon which in part involves the activation of complement by bacterial endotoxin. A monoclonal antibody to human complement factor B, code-named 1H5, which was capab...

journal_title：Infection and immunity

authors： Clardy CW

更新日期：1994-10-01 00:00:00

abstract：:Cross-reactive humoral immune responses between antigens of different developmental stages of the worm Schistosoma mansoni have previously been demonstrated. In contrast, information on antigenic cross-reactivity at the T-cell level is still very sparse. The present study examined the cross-reactive T-cell responses t...

journal_title：Infection and immunity

authors： Lukacs NW,Boros DL

更新日期：1991-09-01 00:00:00

abstract：:Expression of the Vwa+ phenotype of Yersinia pestis in vitro is known to reflect maximum induction of virulence (or V and W antigens) at 37 degrees C with concomitant restriction of cell division. Both phenomena are potentiated by 20 mM Mg2+ and prevented by cultivation at 26 or 37 degrees C with 2.5 mM Ca2+. We have ...

journal_title：Infection and immunity

authors： Perry RD,Brubaker RR

更新日期：1983-04-01 00:00:00

abstract：:Previous experimentation has highlighted a number of difficulties in the development of carrier-based bivalent vaccines (J.-F. Viret and D. Favre, Biologicals 22:361-372, 1994) In an attempt to obviate these carrier strains. Toward this aim, a series of defined rfbInaba deletion (delta rfbInaba) mutants of the cholera...

journal_title：Infection and immunity

authors： Favre D,Cryz SJ Jr,Viret JF

更新日期：1996-02-01 00:00:00

abstract：:Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, ...

journal_title：Infection and immunity

authors： Rivas AJ,Balado M,Lemos ML,Osorio CR

更新日期：2013-09-01 00:00:00

abstract：:Aerobic microorganisms were isolated and identified from 9 of 10 malignant tissues aseptically obtained from surgical patients. The organisms isolated are species commonly associated with the flora of the human body. When these cancer-associated organisms were grown in Trypticase soy broth (BBL Microbiology Systems), ...

journal_title：Infection and immunity

authors： Backus BT,Affronti LF

更新日期：1981-06-01 00:00:00