Abstract:
:Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In the absence of lysogenization, 158 was more virulent than expected. The virulence of 158 and 158-1 did not increase upon lysogenization. A major antigenic difference between 158 and 158-1 was identified that is unrelated to MAV1 and could account for the difference in virulence.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Clapper B,Tu AH,Simmons WL,Dybvig Kdoi
10.1128/IAI.72.12.7322-7325.2004keywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
7322-5issue
12eissn
0019-9567issn
1098-5522pii
72/12/7322journal_volume
72pub_type
杂志文章abstract::Fusobacterium nucleatum is a common oral anaerobe involved in periodontitis that is known to translocate and cause intrauterine infections. In the oral environment, F. nucleatum adheres to a large diversity of species, facilitating their colonization and creating biological bridges that stabilize the multispecies dent...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.02838-14
更新日期:2015-03-01 00:00:00
abstract::Monoclonal antibody MASC1-MR9 of isotype immunoglobulin M was generated in LOU/C rats by immunization with heat-killed Salmonella thompson (serogroup C1, O-antigen 6,7 lipopolysaccharide) bacteria which had been further enriched for O-antigen by coating with homologous lipopolysaccharide. Eight monoclonal antibodies w...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.59.1.229-233.1991
更新日期:1991-01-01 00:00:00
abstract::Organisms of the Mycobacterium avium complex are associated with disseminated infection in patients with AIDS. The mechanisms that account for the survival of the intracellular bacteria are unknown. We document here that infection of C57BL/6 black mice with M. avium 101 triggered interleukin-10 (IL-10) production. The...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.61.7.3093-3097.1993
更新日期:1993-07-01 00:00:00
abstract::Ingestion of 14C-amino acid-labeled Chlamydia psittaci (6BC) by mouse fibroblasts (L cells) was inhibited when the host cells were incubated for 30 min at 37 degrees C in Earle salts containing 10 mug of crystalline trypsin per ml. Tryptic digestion also inhibited the ingestion of 1-mum polystrene latex beads. Trypsin...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.14.3.645-651.1976
更新日期:1976-09-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.55.3.686-691.1987
更新日期:1987-03-01 00:00:00
abstract::Normal bacteria can translocate (migrate) across an intact intestinal mucosa, but the anatomical site of bacterial translocation has not been defined. Gastrointestinal (GI) cross-sections were obtained from mice monoassociated with high cecal concentrations of Escherichia coli, Proteus mirabilis, or Enterococcus faeca...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.59.12.4693-4697.1991
更新日期:1991-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.25.3.820-827.1979
更新日期:1979-09-01 00:00:00
abstract::Although Salmonella enterica serovar Typhimurium can undergo phase variation to alternately express two different types of flagellin subunit proteins, FljB or FliC, no biological function for this phenomenon has been described. In this investigation, we constructed phase-locked derivatives of S. enterica serovar Typhi...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.69.5.3021-3030.2001
更新日期:2001-05-01 00:00:00
abstract::Staphylococcus aureus experimental endocarditis relies on sequential fibrinogen binding (for valve colonization) and fibronectin binding (for endothelial invasion) conferred by peptidoglycan-attached adhesins. Fibronectin-binding protein A (FnBPA) reconciles these two properties--as well as elastin binding--and promot...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00405-08
更新日期:2008-08-01 00:00:00
abstract::Suitability of the rhesus monkey (Macaca mulatta) as an experimental host for evaluation of vaccines against airborne infection with Mycobacterium tuberculosis strain H37Rv was investigated. Nonvaccinated monkeys were exposed to estimated doses of 12, 25, or 49 units of H37Rv in a modified Henderson apparatus, and the...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.2.5.574-582.1970
更新日期:1970-11-01 00:00:00
abstract::Helicobacter pylori colonizes the gastric epithelium of at least 50% of the world's human population, playing a causative role in the development of chronic gastritis, peptic ulcers, and gastric adenocarcinoma. Current evidence indicates that H. pylori can invade epithelial cells in the gastric mucosa. However, relati...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01085-06
更新日期:2006-12-01 00:00:00
abstract::Helicobacter pylori infection is thought to be involved in the development of several gastric diseases. Two H. pylori virulence factors (vacuolating cytotoxin A and cytotoxin-associated gene A) reportedly interact with lipid rafts in gastric epithelial cells. The role of Toll-like receptor (TLR)-mediated signaling in ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.05856-11
更新日期:2012-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.41.2.858-860.1983
更新日期:1983-08-01 00:00:00
abstract::NF-κB is a critical regulator of gene expression during severe infections. NF-κB comprises homo- and heterodimers of proteins from the Rel family. Among them, p50 and p65 have been clearly implicated in the pathophysiology of sepsis. In contrast, the role of cRel in sepsis is still controversial and has been poorly st...
journal_title:Infection and immunity
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doi:10.1128/IAI.00021-11
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abstract::The mechanisms for acquisition of iron by Haemophilus influenzae and their role in pathogenesis are not known. Heme and nonheme sources of iron were evaluated for their effect on growth of type b and nontypable strains of H. influenzae in an iron-restricted, defined medium. All 13 strains acquired iron from heme, hemo...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.56.4.721-725.1988
更新日期:1988-04-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.6.2195-2201.1994
更新日期:1994-06-01 00:00:00
abstract::Escherichia coli 536 (O6:K15:H31), which was isolated from a case of urinary tract infection, determines high nephropathogenicity in a rat pyelonephritis system as measured by renal bacterial counts 7 days after infection. The loss of S fimbrial adhesin formation (Sfa-) (mannose-resistant hemagglutination [Mrh-] and f...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.54.3.761-767.1986
更新日期:1986-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.20.2.476-484.1978
更新日期:1978-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.02101-14
更新日期:2014-10-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00991-07
更新日期:2007-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.57.8.2586-2587.1989
更新日期:1989-08-01 00:00:00
abstract::Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.57.6.1647-1655.1989
更新日期:1989-06-01 00:00:00
abstract::An established cell line (Vero) defective in interferon production was used to evaluate the role of interferon in chronic rubella virus infections of cell cultures. Inoculation of Vero cells with a low multiplicity of virus resulted in the development of carrier cultures which had the characteristics of a regulated in...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.2.2.132-138.1970
更新日期:1970-08-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.50.3.745-752.1985
更新日期:1985-12-01 00:00:00
abstract::Clostridium perfringens type B causes enteritis and enterotoxemia in domestic animals. By definition, these bacteria must produce alpha toxin (CPA), beta toxin (CPB) and epsilon toxin (ETX) although most type B strains also produce perfringolysin O (PFO) and beta2 toxin (CPB2). A recently identified Agr-like quorum-se...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00438-12
更新日期:2012-09-01 00:00:00
abstract::In attempts to reactivate latent herpes simplex virus, we instilled Diplococcus pneumoniae intratracheally into mice harboring latent infections in sacrosciatic spinal ganglia. All mice developed a severe pneumonia within 24 h and were given penicillin therapy. Representative mice that survived the penumonia were sacr...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.11.4.635-639.1975
更新日期:1975-04-01 00:00:00
abstract::Escherichia coli D2 (serotype 07:H-) that was isolated from a child with diarrhea hybridized with an F1845 DNA probe used to detect diffuse adherence. Strain D2 adhered to tissue culture cells (HeLa and HEp-2 cells) in a clustered pattern but did not autoagglutinate on the cell surface and induced the elongation of mi...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.7.2917-2929.1994
更新日期:1994-07-01 00:00:00
abstract::A family of high-molecular-weight (HMW) surface-exposed proteins important in the attachment of nontypeable Haemophilus influenzae (NTHi) to human epithelial cells was previously identified (J. W. St. Geme III, S. Falkow, and S. J. Barenkamp, Proc. Natl. Acad. Sci. USA 90:2875-2879, 1993). In the present investigation...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.10.4460-4468.1994
更新日期:1994-10-01 00:00:00
abstract::Allergic-type immune responses, particularly immunoglobulin E (IgE), correlate with protective immunity in human schistosomiasis. To better understand the mechanisms of parasite elimination we examined the immune correlates of protection in baboons (Papio cynocephalus anubis), which are natural hosts for Schistosoma m...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.67.2.636-642.1999
更新日期:1999-02-01 00:00:00