Iron acquisition by Haemophilus influenzae.

abstract：:Purified group A streptococcal peptidoglycan-polysaccharide (PG-PS) fragments were either de-O-acylated, or acetylated and then de-O-acylated to yield N-acetylated PG-PS. Native PG-PS was poorly degraded, N-acetylated PG-PS was extensively degraded, and de-O-acylated PG-PS was only slightly degraded by hen egg white l...

journal_title：Infection and immunity

authors： Stimpson SA,Lerch RA,Cleland DR,Yarnall DP,Clark RL,Cromartie WJ,Schwab JH

更新日期：1987-01-01 00:00:00

abstract：:Isolated outer membranes of Borrelia burgdorferi 297 were utilized to obtain partial amino acid sequence information for a low-molecular-weight, outer membrane-associated polypeptide. Degenerate oligonucleotide primers based upon this information were used to amplify a 100-bp probe for detection of the corresponding f...

journal_title：Infection and immunity

authors： Lahdenne P,Porcella SF,Hagman KE,Akins DR,Popova TG,Cox DL,Katona LI,Radolf JD,Norgard MV

更新日期：1997-02-01 00:00:00

abstract：:A Mycobacterium tuberculosis strain disrupted in the AraC homologue Rv1931c was isolated. The mutant strain exhibited reduced survival both in macrophages and in a mouse infection model, with survival being restored on complementation with the Rv1931c gene. These results suggest that Rv1931c regulates genes important ...

journal_title：Infection and immunity

authors： Frota CC,Papavinasasundaram KG,Davis EO,Colston MJ

更新日期：2004-09-01 00:00:00

abstract：:K99 prepared by acid precipitation hemagglutinated guinea pig erythrocytes, whereas K99 prepared by chromatography on diethylaminoethyl-Sephadex did not. K99 purified by either procedure hemagglutinated horse erythrocytes. K99 prepared by acid precipitation contained a second antigen not presnet in the K99 prepared by...

journal_title：Infection and immunity

authors： Isaacson RE

更新日期：1978-11-01 00:00:00

abstract：:The pattern of meningococcal surface structure expression in different microenvironments following bloodstream invasion in vivo is not known. We used immunohistochemistry to determine the expression of capsule, type IV pili, and PorA by meningococci residing in the skin lesions of children with purpura fulminans. All ...

journal_title：Infection and immunity

authors： Harrison OB,Robertson BD,Faust SN,Jepson MA,Goldin RD,Levin M,Heyderman RS

更新日期：2002-09-01 00:00:00

abstract：:Detoxified mutants of the Escherichia coli heat-labile toxin (LT) act as mucosal adjuvants to intranasally presented coadministered antigens. Here, we compare the adjuvant activity of a panel of detoxified derivatives of LT, using both intranasal (i.n.) and oral (p.o.) routes of administration. The mutants used as adj...

journal_title：Infection and immunity

authors： Douce G,Giannelli V,Pizza M,Lewis D,Everest P,Rappuoli R,Dougan G

更新日期：1999-09-01 00:00:00

abstract：:The short-term kinetics of fluoride uptake by cells from 20- to 22-h cultures of Streptococcus mutans strain 6715 were studied using rapid filtration and centrifugation techniques. Saline-suspended organisms were diluted with fluoride-containing solutions buffered at four different pH values (2.0, 4.0, 5.5, and 8.2). ...

journal_title：Infection and immunity

authors： Whitford GM,Schuster GS,Pashley DH,Venkateswarlu P

更新日期：1977-12-01 00:00:00

abstract：:The mechanism by which bacterial heat-stable enterotoxins (ST I STA) cause diarrhea in humans and animals has been linked to the activation of an intestinal membrane-bound guanylate cyclase. Guanylin, a recently discovered rat intestinal peptide, is homologous in structure to ST I and can activate guanylate cyclase pr...

journal_title：Infection and immunity

authors： Carpick BW,Gariépy J

更新日期：1993-11-01 00:00:00

abstract：:Vibrio cholerae V86 El Tor Inaba caused experimental cholera in germfree ICR suckling mice. Sucklings born of gnotobiotic mothers monoassociated with the same strain were completely protected against live oral homologous challenge. ...

journal_title：Infection and immunity

authors： Shimamura T,Tazume S,Hashimoto K,Sasaki S

更新日期：1981-10-01 00:00:00

abstract：:Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) by host cells and th...

journal_title：Infection and immunity

authors： Fang R,Hara H,Sakai S,Hernandez-Cuellar E,Mitsuyama M,Kawamura I,Tsuchiya K

更新日期：2014-06-01 00:00:00

abstract：:Toll-like receptor (TLR) signal transduction is a central component of the innate immune response to pathogenic challenge. Although recent studies have begun to elucidate differences in acquired immunity in tissues of the human female reproductive tract, there is a relative paucity of work regarding innate defense mec...

journal_title：Infection and immunity

authors： Pioli PA,Amiel E,Schaefer TM,Connolly JE,Wira CR,Guyre PM

更新日期：2004-10-01 00:00:00

abstract：:Potential vaccine components for protection against atrophic rhinitis in pigs were developed. This was achieved by deletion mutagenesis of the gene encoding the Pasteurella multocida toxin. Four purified toxin derivatives lacking different and widely separated regions in the amino acid sequence were characterized by a...

journal_title：Infection and immunity

authors： Petersen SK,Foged NT,Bording A,Nielsen JP,Riemann HK,Frandsen PL

更新日期：1991-04-01 00:00:00

abstract：:The mechanism by which capsular polysaccharides inhibit phagocytosis is not clearly understood. We investigated the association between a negative surface charge and inhibition of phagocytosis by the capsular polysaccharide of Cryptococcus neoformans. A two-polymer aqueous-phase system containing phosphate ions was us...

journal_title：Infection and immunity

authors： Kozel TR,Reiss E,Cherniak R

更新日期：1980-08-01 00:00:00

abstract：:Groups of mice were immunized either subcutaneously or intranasally with purified Brucella melitensis lipopolysaccharide (LPS) or with LPS as a noncovalent complex with Neisseria meningitidis group B outer membrane protein (LPS-GBOMP). Control mice were inoculated with sterile saline. Two doses of vaccine were given 4...

journal_title：Infection and immunity

authors： Bhattacharjee AK,Izadjoo MJ,Zollinger WD,Nikolich MP,Hoover DL

更新日期：2006-10-01 00:00:00

abstract：:Cell surface proteins SspA and SspB in Streptococcus gordonii and SpaP in Streptococcus mutans are members of the antigen I/II family of polypeptides produced by oral streptococci. These proteins are adhesins and mediate species-specific binding of cells to a variety of host and bacterial receptors. Here we show that ...

journal_title：Infection and immunity

authors： Love RM,McMillan MD,Jenkinson HF

更新日期：1997-12-01 00:00:00

abstract：:An array of pro- and anti-inflammatory mediators of the innate immune system was analyzed in stool, urine, and rectal mucosa samples from adults and children with shigellosis to better understand their role in recovery from and in the immunopathogenesis of the disease. Increased concentrations of lactoferrin (Lf), mye...

journal_title：Infection and immunity

authors： Raqib R,Mia SM,Qadri F,Alam TI,Alam NH,Chowdhury AK,Mathan MM,Andersson J

更新日期：2000-06-01 00:00:00

abstract：:Gamma interferon (IFN-γ) drives antiparasite responses and immunopathology during infection with Plasmodium species. Immunity-related GTPases (IRGs) are a class of IFN-γ-dependent proteins that are essential for cell autonomous immunity to numerous intracellular pathogens. However, it is currently unknown whether IRGs...

journal_title：Infection and immunity

authors： Guo J,McQuillan JA,Yau B,Tullo GS,Long CA,Bertolino P,Roediger B,Weninger W,Taylor GA,Hunt NH,Ball HJ,Mitchell AJ

更新日期：2015-04-01 00:00:00

abstract：:Enteropathogenic Escherichia coli (EPEC) interacts with intestinal epithelial cells, activating host signaling pathways leading to cytoskeletal rearrangements and ultimately diarrhea. In this study, we demonstrate that EPEC interacts with the macrophage-like cell line J774A.1 to inhibit phagocytosis by these cells. An...

journal_title：Infection and immunity

authors： Goosney DL,Celli J,Kenny B,Finlay BB

更新日期：1999-02-01 00:00:00

abstract：:A synthetic medium capable of supporting growth of Vibrio parahaemolyticus is described. Growth yields and generation times were comparable to growth in a complex medium, although Kanagawa hemolysin was undetectable in the synthetic medium. Upon the addition of single amino acids to this synthetic medium, only D-trypt...

journal_title：Infection and immunity

authors： Cherwonogrodzky JW,Clark AG

更新日期：1982-07-01 00:00:00

abstract：:Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the "noncultivable" bacteria responsi...

journal_title：Infection and immunity

authors： Etemadi AH,Convit J

更新日期：1974-07-01 00:00:00

abstract：:Pneumocystis carinii is an ascomycete phylogenetically related to Schizosaccharomyces pombe. Little is known about gene regulation in P. carinii. The removal of introns from pre-mRNA requires spliceosomal recognition of the intron-exon boundary. In S. pombe and higher eukaryotes, this boundary and a branch site within...

journal_title：Infection and immunity

authors： Thomas CF Jr,Leof EB,Limper AH

更新日期：1999-11-01 00:00:00

abstract：:Analysis of the specificity of bactericidal antibodies in normal, convalescent, and postvaccination human sera is important in understanding human immunity to meningococcal infections and can aid in the design of an effective group B vaccine. A collection of human sera, including group C and group B convalescent-phase...

journal_title：Infection and immunity

authors： Schmiel DH,Moran EE,Keiser PB,Brandt BL,Zollinger WD

更新日期：2011-10-01 00:00:00

abstract：:A nasal vaccine, consisting of outer membrane vesicles (OMVs) from group B Neisseria meningitidis, was given to 12 volunteers in the form of nose drops or nasal spray four times at weekly intervals, with a fifth dose 5 months later. Each nasal dose consisted of 250 microg of protein, equivalent to 10 times the intramu...

journal_title：Infection and immunity

authors： Haneberg B,Dalseg R,Wedege E,Høiby EA,Haugen IL,Oftung F,Andersen SR,Naess LM,Aase A,Michaelsen TE,Holst J

更新日期：1998-04-01 00:00:00

abstract：:Genomic DNA fingerprint analysis was performed on 39 Staphylococcus aureus and 28 Enterococcus faecalis endophthalmitis isolates collected from multiple clinical centers. Among 21 S. aureus genomic DNA fingerprint patterns identified, five clonotypes were recovered from multiple unrelated patients and accounted for 58...

journal_title：Infection and immunity

authors： Booth MC,Hatter KL,Miller D,Davis J,Kowalski R,Parke DW,Chodosh J,Jett BD,Callegan MC,Penland R,Gilmore MS

更新日期：1998-01-01 00:00:00

abstract：:Female C57BL/6J mice were infected with Trypanosoma cruzi and subsequently given macrophages or lymphocytes from syngeneic donors which had recovered from the acute infection. Mice which received immune peritoneal macrophages, splenic lymphocytes, or lymph node lymphocytes developed lower mean parasitemias and cumulat...

journal_title：Infection and immunity

authors： Burgess DE,Hanson WL

更新日期：1979-09-01 00:00:00

abstract：:Ultrastructural changes in cells of the mouse footpad are described which occurred during the log phase of multiplication, the plateau, and the stationary phase of growth of Mycobacterium leprae.BALB/c mice were inoculated in the right hind footpad with 5 x 10(3) organisms and sacrificed in pairs at 86 to 173 days aft...

journal_title：Infection and immunity

authors： Evans MJ,Levy L

更新日期：1972-02-01 00:00:00

abstract：:Helicobacter pylori infection of the stomach causes an active immune response that includes stimulation of inducible nitric oxide (NO) synthase (iNOS) expression. Although NO can kill H. pylori, the bacterium persists indefinitely, suggesting that NO production is inadequate. We determined if the NO derived from iNOS ...

journal_title：Infection and immunity

authors： Chaturvedi R,Asim M,Lewis ND,Algood HM,Cover TL,Kim PY,Wilson KT

更新日期：2007-09-01 00:00:00

abstract：:Porphyromonas gingivalis, a periodontopathic bacterium, is known to invade oral epithelial cells in periodontal lesions, although the mechanism is unclear. In the present study, goat polyclonal anti-intercellular adhesion molecule 1 (anti-ICAM-1) antibody inhibited the invasion of P. gingivalis into KB cells (human or...

journal_title：Infection and immunity

authors： Tamai R,Asai Y,Ogawa T

更新日期：2005-10-01 00:00:00

abstract：:Thirty two anaerobic bacterial strains were screened for their in vitro inhibitory activity toward 21 Neisseria gonorrhoeae strains, including two penicillin-resistant strains. From this screening, six anaerobic bacteria belonging to the genera Bacteroides, Peptostreptococcus, and Eubacterium were selected for their l...

journal_title：Infection and immunity

authors： Morin A,Saheb SA,Bisaillon JG,Beaudet R,Sylvestre M

更新日期：1980-06-01 00:00:00

abstract：:We examined the way the major outer membrane protein OmpA of Salmonella enterica serovar Typhimurium is recognized by the mouse immune system, by raising a panel of 12 monoclonal antibodies (MAbs) against this protein. Interaction between OmpA and these MAbs is competitively inhibited with several-hundredfold dilution...

journal_title：Infection and immunity

authors： Singh SP,Williams YU,Miller S,Nikaido H

更新日期：2003-07-01 00:00:00