Enteropathogenic Escherichia coli inhibits phagocytosis.

abstract：:Botulinum C2 toxin has histopathological activity in the mouse intestine and induces fluid accumulation in intestinal loops. The toxin caused degenerative and necrotic changes in the intestinal mucosa: intracellular vacuolization of epithelial cells, desquamation and necrosis of the villous epithelium, intercellular e...

journal_title：Infection and immunity

authors： Ohishi I,Odagiri Y

更新日期：1984-01-01 00:00:00

abstract：:Clostridium perfringens type A food poisoning is the second most commonly identified bacterial food-borne illness. Sporulation contributes to this disease in two ways: (i) most food-poisoning strains form exceptionally resistant spores to facilitate their survival of food-associated stresses, and (ii) the enterotoxin ...

journal_title：Infection and immunity

authors： Li J,McClane BA

更新日期：2010-10-01 00:00:00

abstract：:The role of a plasmid in the virulence activity of an enteropathogenic Escherichia coli (EPEC) strain belonging to serotype 0111:NM was examined. EPEC strain B171, which is resistant to chloramphenicol, streptomycin, sulfathiazole, and tetracycline, harbors a 54-megadalton plasmid, pYR111, and exhibits localized adher...

journal_title：Infection and immunity

authors： Riley LW,Junio LN,Libaek LB,Schoolnik GK

更新日期：1987-09-01 00:00:00

abstract：:Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-derived vacuole. A determinant necessary for C. burnetii virulence is the Dot/Icm type IVB secretion system (T4SS). The Dot/Icm system delivers more than 100 proteins, called type IV effectors (T4Es), across the vacuolar membrane into the hos...

journal_title：Infection and immunity

authors： Crabill E,Schofield WB,Newton HJ,Goodman AL,Roy CR

更新日期：2018-03-22 00:00:00

abstract：:Despite the high prevalence of cutaneous infections, little is known about the role of host immune responsiveness during Staphylococcus aureus dermatitis. We have recently described a murine model of infectious dermatitis induced by superantigen-producing S. aureus. To assess the role of neutrophils in staphylococcal ...

journal_title：Infection and immunity

authors： Mölne L,Verdrengh M,Tarkowski A

更新日期：2000-11-01 00:00:00

abstract：:We studied apoptosis in a human ileocecal adenocarcinoma tumor cell line (HCT-8) infected with Cryptosporidium parvum, from 2 to 72 h postinfection (h.p.i.). At 2 h.p.i., the percentage of annexin V-positive cells in the cell culture had increased to 10% compared to 2.5% in noninfected control culture; sorted infected...

journal_title：Infection and immunity

authors： Mele R,Gomez Morales MA,Tosini F,Pozio E

更新日期：2004-10-01 00:00:00

abstract：:The predominant gram-positive bacteria in 47 fecal specimens from 10 healthy men were studied by microscopic and cultural counts, by the characterization and tentative identification of isolates, and by the use of fluorescein isothiocyanate (FITC)-conjugated globulins prepared using some of the isolates. Gram-positive...

journal_title：Infection and immunity

authors： Gossling J,Slack JM

更新日期：1974-04-01 00:00:00

abstract：:Previous studies indicated that inorganic pyrophosphatase of Ascaris suum (AsPPase) plays an important role in larval survival in the host. Here we describe a precise role for AsPPase in larval molting and development and also describe the potential role of recombinant AsPPase (rAsPPase) in protective immunity to A. s...

journal_title：Infection and immunity

authors： Islam MK,Miyoshi T,Yamada M,Tsuji N

更新日期：2005-04-01 00:00:00

abstract：:The role of cysteine proteinases in adherence of Trichomonas vaginalis NYH 286 to HeLa and human vaginal epithelial cells was evaluated. Only pretreatment of trichomonads, but not epithelial cells, with N-alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK), an inhibitor of trichomonad cysteine proteinases, greatly dimin...

journal_title：Infection and immunity

authors： Arroyo R,Alderete JF

更新日期：1989-10-01 00:00:00

abstract：:The Toll-like receptor 2 (TLR2)/TLR1 receptor complex responds to amyloid fibrils, a common component of biofilm material produced by members of the phyla Firmicutes, Bacteroidetes, and Proteobacteria. To determine whether this TLR2/TLR1 ligand stimulates inflammatory responses when bacteria enter intestinal tissue, w...

journal_title：Infection and immunity

authors： Nishimori JH,Newman TN,Oppong GO,Rapsinski GJ,Yen JH,Biesecker SG,Wilson RP,Butler BP,Winter MG,Tsolis RM,Ganea D,Tükel Ç

更新日期：2012-12-01 00:00:00

abstract：:The role of antibody in protection against infection with Cryptococcus neoformans is undefined. In this paper we describe the development of opsonic activity in the cerebrospinal fluid (CSF) of rabbits in response to cryptococcal meningitis. The opsonin appeared to be immunoglobulin G (IgG); the activity was heat stab...

journal_title：Infection and immunity

authors： Hobbs MM,Perfect JR,Granger DL,Durack DT

更新日期：1990-07-01 00:00:00

abstract：:CD8(+) T lymphocytes often play a primary role in adaptive immunity to cytosolic microbial pathogens. Surprisingly, CD8(+) T cells are not required for protective immunity to the enteric pathogen Shigella flexneri, despite the ability of Shigella to actively secrete proteins into the host cytoplasm, a location from wh...

journal_title：Infection and immunity

authors： Jehl SP,Doling AM,Giddings KS,Phalipon A,Sansonetti PJ,Goldberg MB,Starnbach MN

更新日期：2011-05-01 00:00:00

abstract：:Vitamin E protects nonimmunized and immunized mice against fatal Diplococcus pneumoniae type I (DpI) infection. A dietary supplementation of 180 mg of dl-alpha-tocopheryl acetate per kg of diet increased survival of nonimmunized mice from 20 to 80% when challenged with 20 organisms, and of mice immunized with 0.5 ng o...

journal_title：Infection and immunity

authors： Heinzerling RH,Tengerdy RP,Wick LL,Lueker DC

更新日期：1974-12-01 00:00:00

abstract：:A strain of a nutritionally deficient streptococcus was shown to undergo morphological aberrations according to pyridoxal concentrations in the growth medium. Filamentous rod-shaped cells, observed by electron microscopy, predominated in the presence of decreasing concentrations. Multiple invaginations in the outer ce...

journal_title：Infection and immunity

authors： Clark RB,Gordon RE,Bottone EJ,Reitano M

更新日期：1983-10-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) causes repeated respiratory infections in patients with chronic lung diseases. These infections are characterized by a brisk inflammatory response which results in the accumulation of polymorphonucleated cells in the lungs and is dependent on the expression and secretion of pr...

journal_title：Infection and immunity

authors： Clemans DL,Bauer RJ,Hanson JA,Hobbs MV,St Geme JW 3rd,Marrs CF,Gilsdorf JR

更新日期：2000-08-01 00:00:00

abstract：:Gamma interferon (IFN-γ) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) in human epithelial cells, the permissive cells for the obligate intracellular bacterium Chlamydia trachomatis. IDO1 depletes tryptophan by catabolizing it to kynurenine with consequences for C. trachom...

journal_title：Infection and immunity

authors： Ibana JA,Belland RJ,Zea AH,Schust DJ,Nagamatsu T,AbdelRahman YM,Tate DJ,Beatty WL,Aiyar AA,Quayle AJ

更新日期：2011-11-01 00:00:00

abstract：:In mammalian hosts, Leishmania sp. parasites are obligatory intracellular organisms that invade macrophages and dendritic cells (DC), where they reside in endocytic organelles termed parasitophorous vacuoles (PV). Most of the present knowledge of the characteristics of PV harboring Leishmania sp. is derived from studi...

journal_title：Infection and immunity

authors： Körner U,Fuss V,Steigerwald J,Moll H

更新日期：2006-02-01 00:00:00

abstract：:The polysaccharide antigen preparations from serotype a and serotype d strains of Streptococcus mutans contained both a serotype-specific antigenic determinant and a common a-d antigenic determinant, as demonstrated by agar gel diffusion studies and a quantitative cross-precipitin assay. The chromatographically purifi...

journal_title：Infection and immunity

authors： Linzer R,Mukasa H,Slade HD

更新日期：1975-10-01 00:00:00

abstract：:Scrub typhus is a potentially lethal infection that is caused by the obligate intracellular bacterium Orientia tsutsugamushi The roles of Toll-like receptor 2 (TLR2) and TLR4 in innate recognition of O. tsutsugamushi have not been elucidated. By overexpression of TLR2 or TLR4 in HEK293 cells, we demonstrated that TLR2...

journal_title：Infection and immunity

authors： Gharaibeh M,Hagedorn M,Lilla S,Hauptmann M,Heine H,Fleischer B,Keller C

更新日期：2016-11-18 00:00:00

abstract：:Natural killer (NK) cells are critically involved in the early immune response against various intracellular pathogens, including Coxiella burnetii and Chlamydia psittaciChlamydia-infected NK cells functionally mature, induce cellular immunity, and protect themselves by killing the bacteria in secreted granules. Here,...

journal_title：Infection and immunity

authors： Matthiesen S,Zaeck L,Franzke K,Jahnke R,Fricke C,Mauermeir M,Finke S,Lührmann A,Knittler MR

更新日期：2020-10-19 00:00:00

abstract：:Immunoglobulin A (IgA) was prepared from samples of parotid saliva collected from two individuals over a 150-day period. Standardized solutions of the IgA were tested for agglutinating antibody activity against strains of streptococcus salivarius, S. sanguis, S. mitis, and S. mutans that had been isolated from a homol...

journal_title：Infection and immunity

authors： Bratthall D,Gibbons RJ

更新日期：1975-03-01 00:00:00

abstract：:Murine cerebral malaria (CM) induced by Plasmodium berghei ANKA kills susceptible mice within 24 to 48 h of onset of symptoms and is characterized by the production of inflammatory cytokines in the brain. C57BL/6J mice are sensitive to lethal CM, while A/J mice are resistant. These strains of mice were immunized with ...

journal_title：Infection and immunity

authors： Jennings VM,Lal AA,Hunter RL

更新日期：1998-12-01 00:00:00

abstract：:In Vibrio cholerae, the transmembrane DNA binding proteins, ToxR and TcpP, activate expression of the regulatory gene toxT in response to specific environmental signals. The resulting enhanced level of ToxT leads to a coordinated increase in the production of a subset of virulence factors, including cholera toxin (CT)...

journal_title：Infection and immunity

authors： Krishnan HH,Ghosh A,Paul K,Chowdhury R

更新日期：2004-07-01 00:00:00

abstract：:Increased protection against a virulent challenge with Mycobacterium tuberculosis is induced mainly by a previous immunization with living avirulent mycobacteria, usually Mycobacterium bovis BCG. Only a transient and marginal protection is obtained after immunization with bacterial extracts or dead bacteria. Both livi...

journal_title：Infection and immunity

authors： Romain F,Laqueyrerie A,Militzer P,Pescher P,Chavarot P,Lagranderie M,Auregan G,Gheorghiu M,Marchal G

更新日期：1993-02-01 00:00:00

abstract：:The Corynebacterium diphtheriae hmuO gene encodes a heme oxygenase that is involved in the utilization of heme as an iron source. Transcription of hmuO is activated by heme or hemoglobin and repressed by iron and DtxR. Previous studies with Escherichia coli showed that heme-dependent transcriptional activation of an h...

journal_title：Infection and immunity

authors： Bibb LA,King ND,Kunkle CA,Schmitt MP

更新日期：2005-11-01 00:00:00

abstract：:Acute pyelonephritis, a complication of Escherichia coli bacteriuria, must represent a bacterial invasion through the kidney epithelium. To study this process, we overlaid bacterial suspensions onto monolayers of cultured human kidney proximal tubular epithelial cells and measured cytotoxicity by release of lactate de...

journal_title：Infection and immunity

authors： Mobley HL,Green DM,Trifillis AL,Johnson DE,Chippendale GR,Lockatell CV,Jones BD,Warren JW

更新日期：1990-05-01 00:00:00

abstract：:Shiga toxin-producing Escherchia coli (STEC) comprises a group of attaching and effacing (A/E) enteric pathogens of animals and humans. Natural and experimental infection of calves with STEC may result in acute enteritis or subclinical infection, depending on serotype- and host-specific factors. To quantify intestinal...

journal_title：Infection and immunity

authors： Stevens MP,Marchès O,Campbell J,Huter V,Frankel G,Phillips AD,Oswald E,Wallis TS

更新日期：2002-02-01 00:00:00

abstract：:Pseudomonas aeruginosa, an important opportunistic pathogen of humans, exploits epithelial damage to establish infection. We have rigorously explored the role of N-glycoproteins and heparan sulfate proteoglycans (HSPGs) in P. aeruginosa-mediated attachment and subsequent downstream events at the apical (AP) and basola...

journal_title：Infection and immunity

authors： Bucior I,Mostov K,Engel JN

更新日期：2010-03-01 00:00:00

abstract：:Fractionation of the culture medium showed that Streptococcus salivarius ATCC 25975 secreted a glucosyltransferase (Gtf) that was primer independent. On the basis of this observation, a gene library of S. salivarius chromosomal DNA cloned into lambda L47.1 was screened for a gene(s) coding for such an activity. As a r...

journal_title：Infection and immunity

authors： Simpson CL,Giffard PM,Jacques NA

更新日期：1995-02-01 00:00:00

abstract：:One of the chromosomal segments associated with the virulence of Shigella flexneri and transferred to Escherichia coli K-12 by conjugation has been shown to code for the production of aerobactin and for the synthesis of an iron-regulated 76,000-dalton (76K) outer membrane protein. Analysis of various E. coli K-12-S. f...

journal_title：Infection and immunity

authors： Griffiths E,Stevenson P,Hale TL,Formal SB

更新日期：1985-07-01 00:00:00