Critical role of cRel subunit of NF-κB in sepsis survival.

abstract：:A panel of monoclonal antibodies (MAbs) specific for the heat-stable enterotoxin (STh) of enterotoxigenic Escherichia coli was produced. All four MAbs (8G7, 53-4, 11C, and SH1) bound to native STh in an enzyme-linked immunosorbent assay to various degrees, with clone SH1 showing the best affinity. The MAbs were screen...

journal_title：Infection and immunity

authors： Takeda T,Nair GB,Suzuki K,Zhe HX,Yokoo Y,De Mol P,Hemelhof W,Butzler JP,Takeda Y,Shimonishi Y

更新日期：1993-01-01 00:00:00

abstract：:Phagocytosis, H2O2 production, Mac-1 expression, and in vivo elimination of Listeria monocytogenes were enhanced in granulocyte colony-stimulating factor (G-CSF)-treated mice. Transfer of polymorphonuclear leukocytes prolonged survival of mice infected with a lethal dose of L. monocytogenes. G-CSF augments the functio...

journal_title：Infection and immunity

authors： Shinomiya N,Tsuru S,Katsura Y,Kayashima S,Nomoto K

更新日期：1991-12-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) is a commensal microorganism of the human nasopharynx, and yet is also an opportunistic pathogen of the upper and lower respiratory tracts. Host microenvironments influence gene expression patterns, likely critical for NTHi persistence. The host sequesters iron as a mechanism ...

journal_title：Infection and immunity

authors： Harrison A,Santana EA,Szelestey BR,Newsom DE,White P,Mason KM

更新日期：2013-04-01 00:00:00

abstract：:We developed an efficient electrotransformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effects of features of the transforming DNA on transformation efficiency and fate of the transforming DNA and to demonstrate fungal expression of two recombinant Escherichia coli genes, hp...

journal_title：Infection and immunity

authors： Woods JP,Heinecke EL,Goldman WE

更新日期：1998-04-01 00:00:00

abstract：:This study was undertaken to ascertain the relationship between complement-derived chemotactic factors and complement component 1 inactivator (C1INA) enhancement of neutrophil chemotaxis. Studies were also designed to determine whether the C1s- reactive or binding site on C1INA was functional in altering chemotactic r...

journal_title：Infection and immunity

authors： Patrick RA,Hollers JC,Liu DY,Giese BH,Smith CW

更新日期：1980-06-01 00:00:00

abstract：:Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known. H...

journal_title：Infection and immunity

authors： Porter PC,Roberts L,Fields A,Knight M,Qian Y,Delclos GL,Han S,Kheradmand F,Corry DB

更新日期：2011-11-01 00:00:00

abstract：:Using fluorescent antibody techniques (FA) and light microscopy (LM) and electron microscopy (EM), this paper describes the morphological features of the ileum in the DK1 mouse orally challenged with adenovirus K87. At the peak of infection, virus is easily identified by FA in the epithelium of the villi and crypts of...

journal_title：Infection and immunity

authors： Takeuchi A,Hashimoto K

更新日期：1976-02-01 00:00:00

abstract：:Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

journal_title：Infection and immunity

authors： Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

更新日期：2012-03-01 00:00:00

abstract：:We previously showed the requirement of both T cells and gamma interferon (IFN-gamma)-producing non-T cells for the genetic resistance of BALB/c mice to the development of toxoplasmic encephalitis (TE). In order to define the role of IFN-gamma production and the perforin-mediated cytotoxicity of T cells in this resist...

journal_title：Infection and immunity

authors： Wang X,Kang H,Kikuchi T,Suzuki Y

更新日期：2004-08-01 00:00:00

abstract：:In the present study, the roles of interleukin 12 (IL-12) and IL-18 and their possible interaction during superantigen-induced responses were studied by injection of staphylococcal enterotoxin B (SEB) into mice. These data suggest that the role of IL-12 in SEB-induced responses is limited to sustaining gamma interfero...

journal_title：Infection and immunity

authors： Lauw FN,Florquin S,Speelman P,van Deventer SJ,van der Poll T

更新日期：2001-09-01 00:00:00

abstract：:Streptococcus agalactiae (group B streptococcus [GBS]) is the leading cause of neonatal pneumonia, sepsis, and meningitis. An in silico genome analysis indicated that GBS strain NEM316 encodes 35 proteins containing an LPXTG motif which are thought to be covalently linked to the peptidoglycan by an enzyme called sorta...

journal_title：Infection and immunity

authors： Lalioui L,Pellegrini E,Dramsi S,Baptista M,Bourgeois N,Doucet-Populaire F,Rusniok C,Zouine M,Glaser P,Kunst F,Poyart C,Trieu-Cuot P

更新日期：2005-06-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for large numbers of postsurgical nosocomial infections across the United States and worldwide. Propofol anesthesia is widely used in surgery and in intensive care units, and recent evidence indicates that even brief exposure to propofol can substantial...

journal_title：Infection and immunity

authors： Visvabharathy L,Freitag NE

更新日期：2017-06-20 00:00:00

abstract：:Lipopolysaccharide (LPS) structure impacts the bactericidal action of cationic peptides, such as polymyxin B (PMB), and sensitivity to killing by normal human serum (NHS). Cultivation of different subspecies strains of Yersinia pestis isolated from unrelated geographic origins at various temperatures (mammals, 37 degr...

journal_title：Infection and immunity

authors： Anisimov AP,Dentovskaya SV,Titareva GM,Bakhteeva IV,Shaikhutdinova RZ,Balakhonov SV,Lindner B,Kocharova NA,Senchenkova SN,Holst O,Pier GB,Knirel YA

更新日期：2005-11-01 00:00:00

abstract：:Serotypes A and B of the relapsing fever spirochete Borrelia turicatae produce different disease manifestations in infected mice. Whereas serotype B causes more severe arthritis and reaches higher densities in the blood of mice than serotype A, serotype A invades the central nervous system earlier than serotype B duri...

journal_title：Infection and immunity

authors： Pennington PM,Cadavid D,Barbour AG

更新日期：1999-09-01 00:00:00

abstract：:The adsorption of (3)H-labeled Streptococcus mutans 6715 cells to disks of hydroxyapatite (HA) was studied. The number of streptococci that adsorbed was logarithmically related to the concentration of cells available up to at least 2 x 10(8) per ml; equilibrium occurred within 45 min. Assay reliability was verified by...

journal_title：Infection and immunity

authors： Clark WB,Gibbons RJ

更新日期：1977-11-01 00:00:00

abstract：:Infections caused by organisms of the Mycobacterium avium complex occur in approximately 50 to 60% of patients with AIDS. M. avium is an intracellular pathogen that survives and multiplies within mononuclear phagocytes. In this study, we investigated the uptake of M. avium grown within macrophages (intracellular growt...

journal_title：Infection and immunity

authors： Bermudez LE,Parker A,Goodman JR

更新日期：1997-05-01 00:00:00

abstract：:A total of 32 patients with Plasmodium falciparum malaria were studied. Of these, 23 had benign infections, and 9 had typical cerebral malaria. Cryoglobulins, circulating immune complexes detected by a C1q-binding assay, and hypocomplementemia were found in eight of nine patients with cerebral malaria. Raised levels o...

journal_title：Infection and immunity

authors： Adam C,Géniteau M,Gougerot-Pocidalo M,Verroust P,Lebras J,Gibert C,Morel-Maroger L

更新日期：1981-02-01 00:00:00

abstract：:Gamma interferon (IFN-γ) drives antiparasite responses and immunopathology during infection with Plasmodium species. Immunity-related GTPases (IRGs) are a class of IFN-γ-dependent proteins that are essential for cell autonomous immunity to numerous intracellular pathogens. However, it is currently unknown whether IRGs...

journal_title：Infection and immunity

authors： Guo J,McQuillan JA,Yau B,Tullo GS,Long CA,Bertolino P,Roediger B,Weninger W,Taylor GA,Hunt NH,Ball HJ,Mitchell AJ

更新日期：2015-04-01 00:00:00

abstract：:Acinetobacter baumannii is a pathogen of increasing medical importance with a propensity to be multidrug resistant, thereby making treatment challenging. Little is known of virulence traits in A. baumannii. To identify virulence factors and potential drug targets, random transposon (Tn) mutants derived from the A. bau...

journal_title：Infection and immunity

authors： Russo TA,Luke NR,Beanan JM,Olson R,Sauberan SL,MacDonald U,Schultz LW,Umland TC,Campagnari AA

更新日期：2010-09-01 00:00:00

abstract：:Ecto-5'-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effects during inflamma...

journal_title：Infection and immunity

authors： Kao DJ,Saeedi BJ,Kitzenberg D,Burney KM,Dobrinskikh E,Battista KD,Vázquez-Torres A,Colgan SP,Kominsky DJ

更新日期：2017-09-20 00:00:00

abstract：:Attempts were made to isolate an antigen(s) from Candida albicans suitable for detecting hypersensitivity in a murine model of candidiasis. Using footpad reactivity in cutaneously infected animals as the assay, comparisons were made of two commercial extracts and cell wall and cytoplasmic preparations made in the labo...

journal_title：Infection and immunity

authors： Domer JE,Moser SA

更新日期：1978-04-01 00:00:00

abstract：:Influenza A/Scotland/74 (H3N2) and A/Victoria/75 (H3N2) cold-adapted (ca) recombinant viruses, prepared by mating the A/Ann Arbor/6/60 (H2N2) ca donor virus and influenza A wild-type virus, were evaluated in adult seronegative volunteers (serum hemagglutination-inhibiting antibody titer,

journal_title：Infection and immunity

authors： Murphy BR,Holley HP Jr,Berquist EJ,Levine MM,Spring SB,Maassab HF,Kendal AP,Chanock RM

更新日期：1979-02-01 00:00:00

abstract：:We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate ...

journal_title：Infection and immunity

authors： Delogu G,Sanguinetti M,Posteraro B,Rocca S,Zanetti S,Fadda G

更新日期：2006-05-01 00:00:00

abstract：:Ehrlichia risticii incubated with mouse peritoneal macrophages elicited with thioglycolate broth survived and replicated, thereby allowing examination of the effects of several immunopotentiating agents. Treatment of the macrophages with recombinant murine gamma interferon (rMuIFN-gamma) in vitro at 1 day before or 3 ...

journal_title：Infection and immunity

authors： Park J,Rikihisa Y

更新日期：1991-10-01 00:00:00

abstract：:Parasite antigens which bind to host cell molecules of approximately 32 and 34 kilodaltons (kDa) were identified in supernatant fluids obtained from axenic cultures of Trypanosoma cruzi. These parasite components were first detected in culture supernatants obtained after 2 weeks in culture. Immunoblot analysis of cult...

journal_title：Infection and immunity

authors： Davis CD,Kuhn RE

更新日期：1990-06-01 00:00:00

abstract：:The protection and immune response to infection caused by the parasite Schistosoma mansoni were studied by comparison of two murine irradiated-vaccine models. Mice were exposed from 1 to 4 times to infective-stage cercariae attenuated with either a moderate dose (15 kilorads) or a high dose (50 kilorads) of radiation....

journal_title：Infection and immunity

authors： Reynolds SR,Harn DA

更新日期：1992-01-01 00:00:00

abstract：:Mice infected with various strains of Salmonella enteritidis and S. typhimurium were found to be more sensitive to the cell wall lipopolysaccharide (LPS) extracted from certain strains of Salmonella than noninfected mice. This hypersensitivity was induced by those smooth or rough strains which possessed a polysacchari...

journal_title：Infection and immunity

authors： Kawakami M,Hara Y,Osawa N

更新日期：1971-11-01 00:00:00

abstract：:A radioimmunoprecipitation method has been devised which permits the direct identification of those proteins which are both exposed on the cell surface of Haemophilus influenzae type b and accessible to antibody. Both extrinsically and intrinsically radiolabeled cells of this organism were employed as the sources of a...

journal_title：Infection and immunity

authors： Hansen EJ,Frisch CF,Johnston KH

更新日期：1981-09-01 00:00:00

abstract：:Most Campylobacter jejuni strains are sensitive and most Campylobacter fetus strains are resistant to the bactericidal activity in normal human serum. We purified lipopolysaccharides from Campylobacter strains to determine whether their composition and structure relate to serum susceptibility. The lipopolysaccharide o...

journal_title：Infection and immunity

authors： Perez Perez GI,Blaser MJ

更新日期：1985-02-01 00:00:00

abstract：:The C-terminal 19-kDa domain of merozoite surface protein 1 (MSP1₁₉) is the target of protective antibodies but alone is poorly immunogenic. Previously, using the Plasmodium yoelii murine model, we fused P. yoelii MSP1₁₉ (PyMSP1₁₉) with full-length P. yoelii merozoite surface protein 8 (MSP8). Upon immunization, the M...

journal_title：Infection and immunity

authors： Alaro JR,Angov E,Lopez AM,Zhou H,Long CA,Burns JM Jr

更新日期：2012-07-01 00:00:00