Growth within macrophages increases the efficiency of Mycobacterium avium in invading other macrophages by a complement receptor-independent pathway.

abstract：:Escherichia coli C25 maintained population levels of 10(9) to 10(10) per g of cecum and translocated to 100% of the middle mesenteric lymph nodes in gnotobiotic mice monoassociated with E. coli C25. Intragastric inoculation of these mice with the cecal contents from specific-pathogen-free mice reduced the population l...

journal_title：Infection and immunity

authors： Berg RD

更新日期：1980-09-01 00:00:00

abstract：:The rate of clearance of Vibrio fetus var. venerealis was measured by using in vivo and in vitro methods. The rate of clearance from the circulating blood increased in immune rabbits and reached a plateau 4 days after immunization. Thereafter in vivo clearance did not increase further despite rising agglutinin titers....

journal_title：Infection and immunity

authors： Carrier SP,Kramer TT

更新日期：1971-06-01 00:00:00

abstract：:Collectins play important roles in host defense against infectious microorganisms. We now demonstrate that the serum collectins mannose-binding lectin (MBL) and conglutinin have less ability to bind to, aggregate, and enhance neutrophil uptake of several strains of gram-negative and gram-positive bacteria than pulmona...

journal_title：Infection and immunity

authors： Hartshorn KL,White MR,Crouch EC

更新日期：2002-11-01 00:00:00

abstract：:Since 1984, it has been known that spotted fever group rickettsiosis exists in Japan. We isolated three strains of the causative rickettsiae, designated Katayama, Misaka, and Abe, from patients with the disease and studied the characteristics of the isolates. Nude mice and cyclophosphamide-treated mice died after infe...

journal_title：Infection and immunity

authors： Okada T,Tange Y,Kobayashi Y

更新日期：1990-04-01 00:00:00

abstract：:Pasteurella (Mannheimia) haemolytica leukotoxin (Lkt) causes cell type- and species-specific effects in ruminant leukocytes. Recent studies indicate that P. haemolytica Lkt binds to bovine CD18, the common subunit of all beta2 integrins. We designed experiments with the following objectives: to identify which member o...

journal_title：Infection and immunity

authors： Jeyaseelan S,Hsuan SL,Kannan MS,Walcheck B,Wang JF,Kehrli ME,Lally ET,Sieck GC,Maheswaran SK

更新日期：2000-01-01 00:00:00

abstract：:The appearance of lymphotoxin in the culture fluid of phytohemagglutinin (PHA)-stimulated mouse spleen cells required two cell fractions that were separated by adherence to plastic. Upon stimulation with PHA, neither cell fraction alone produced significant amounts of lymphotoxin; however, when the cell fractions were...

journal_title：Infection and immunity

authors： Aksamit RR,Leonard EJ

更新日期：1982-06-01 00:00:00

abstract：:Natural bactericidal resistance to Mycobacterium bovis BCG is under the control of a single gene, designated Bcg. Lung granuloma formation in susceptible (Bcgs) and resistant (Bcgr) mice was studied in two sets of Bcg-congenic systems, namely, the BALB/c (Bcgs)-C.D2 (BALB/c.Bcgr) pair and the B10.A (Bcgs)-B10.Ar (Bcgr...

journal_title：Infection and immunity

authors： Sato IY,Kobayashi K,Kasama T,Kaga S,Kasahara K,Kanemitsu H,Nakatani K,Takahashi T,Nakamura RM,Skamene E

更新日期：1990-05-01 00:00:00

abstract：:Five monoclonal antibodies (MAbs) were partially characterized and tested for their ability to inhibit penetration of Madin-Darby bovine kidney (MDBK) cells by sporozoites of Eimeria bovis. By indirect fluorescent-antibody assays, all MAbs reacted with acetone-fixed sporozoites, but only two MAbs, EbS9 (immunoglobulin...

journal_title：Infection and immunity

authors： Whitmire WM,Kyle JE,Speer CA,Burgess DE

更新日期：1988-10-01 00:00:00

abstract：:The complement-fixing (CF) activity of antigens from cultured Burkitt lymphoma cells was determined by using normal American sera as the source of antibody. Approximately 75% of the sera fixed complement with the positive cell lines. These lines contained the herpes-like virus detectable by electron microscopy. The co...

journal_title：Infection and immunity

authors： McCormick KJ,Stenback WA,Mumford DM,Trentin JJ

更新日期：1971-07-01 00:00:00

abstract：:Experiments outlined here investigate the role of nitric oxide (NO) in the pathogenesis of Plasmodium falciparum-induced malarial anemia (MA). The results show that ex vivo and in vitro NO synthase (NOS) activity in peripheral blood mononuclear cells (PBMCs) is significantly elevated in children with MA and inversely ...

journal_title：Infection and immunity

authors： Keller CC,Kremsner PG,Hittner JB,Misukonis MA,Weinberg JB,Perkins DJ

更新日期：2004-08-01 00:00:00

abstract：:The short-term kinetics of fluoride uptake by cells from 20- to 22-h cultures of Streptococcus mutans strain 6715 were studied using rapid filtration and centrifugation techniques. Saline-suspended organisms were diluted with fluoride-containing solutions buffered at four different pH values (2.0, 4.0, 5.5, and 8.2). ...

journal_title：Infection and immunity

authors： Whitford GM,Schuster GS,Pashley DH,Venkateswarlu P

更新日期：1977-12-01 00:00:00

abstract：:Serotype b-specific polysaccharide antigen (SPA) was extracted from whole cells of Actinobacillus actinomycetemcomitans Y4 by autoclaving and purified by chromatography on DEAE-Sephadex A-25 and Sephacryl S-300. SPA induced the release of monocyte and leukocyte chemotactic factors by human monocytes. Polymyxin B had a...

journal_title：Infection and immunity

authors： Yamaguchi N,Yamashita Y,Ikeda D,Koga T

更新日期：1996-07-01 00:00:00

abstract：:Heart and muscle tissues appear to be specific target organs for the in vivo inhibition of protein synthesis by diphtheria toxin. ...

journal_title：Infection and immunity

authors： Bowman CG,Imhoff JG,Bonventre PF

更新日期：1970-11-01 00:00:00

abstract：:Vibrio parahaemolyticus, a gram-negative marine bacterium, is an important pathogen causing food-borne gastroenteritis or septicemia. Recent genome sequencing of the RIMD2210633 strain (a Kanagawa phenomenon-positive clinical isolate of serotype O3:K6) revealed that the strain has two sets of gene clusters that encode...

journal_title：Infection and immunity

authors： Ono T,Park KS,Ueta M,Iida T,Honda T

更新日期：2006-02-01 00:00:00

abstract：:Four classes of mutants of type III group B streptococcus were isolated by serial subculture of the wild-type strain in the presence of type III-specific rabbit antiserum. Class I mutants no longer synthesized sialic acid but still elaborated the core antigen. Class II mutants maintained the ability to synthesize sial...

journal_title：Infection and immunity

authors： Yeung MK,Mattingly SJ

更新日期：1983-10-01 00:00:00

abstract：:Both rat alveolar macrophages and a human macrophages cell line with characteristics of human tissue (e.g., alveolar) macrophages (THP-1) were found to inhibit the germination of Rhizopus spores. However, the conditions under which fungistatic activity occurs are different for these two cell types. The inhibition of R...

journal_title：Infection and immunity

authors： Jorens PG,Boelaert JR,Halloy V,Zamora R,Schneider YJ,Herman AG

更新日期：1995-11-01 00:00:00

abstract：:The stimulation of mononuclear phagocytes by lipopolysaccharide (LPS) is facilitated by the binding of complexes of LPS and LPS-binding protein to CD14. Although it is clear that CD14 is involved in LPS-induced signaling, other investigators have hypothesized the existence of additional signaling pathways in macrophag...

journal_title：Infection and immunity

authors： Lynn WA,Liu Y,Golenbock DT

更新日期：1993-10-01 00:00:00

abstract：:Intra-abdominal polymicrobial infections cause significant morbidity and mortality. An experimental mouse model of Candida albicans-Staphylococcus aureus intra-abdominal infection (IAI) results in 100% mortality by 48 to 72 h postinoculation, while monomicrobial infections are avirulent. Mortality is associated with r...

journal_title：Infection and immunity

authors： Nash EE,Peters BM,Fidel PL,Noverr MC

更新日期：2015-10-19 00:00:00

abstract：:Cimetidine is a powerful H2 receptor antagonist that eliminates histamine's effects on chemotaxis, phagocytosis, and superoxide anion production by phagocytes. The purpose of this study was to analyze the clinical and histopathological changes associated with experimental periodontitis in rabbits in response to topica...

journal_title：Infection and immunity

authors： Hasturk H,Kantarci A,Ebrahimi N,Andry C,Holick M,Jones VL,Van Dyke TE

更新日期：2006-04-01 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis is the causative agent of Johne's disease in cattle. The complex, multifaceted interaction of M. avium subsp. paratuberculosis with its host includes dampening the ability of infected cells to respond to stimuli that promote M. avium subsp. paratuberculosis clearance. By dis...

journal_title：Infection and immunity

authors： Arsenault RJ,Li Y,Maattanen P,Scruten E,Doig K,Potter A,Griebel P,Kusalik A,Napper S

更新日期：2013-01-01 00:00:00

abstract：:Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a strong Th1 response that leads to skin lesion development. In areas where L. braziliensis transmission is endemic, up to 15% of healthy subjects have tested positive for delayed-type hypersensitivity to soluble leishmania antigen (SLA...

journal_title：Infection and immunity

authors： Cardoso TM,Machado Á,Costa DL,Carvalho LP,Queiroz A,Machado P,Scott P,Carvalho EM,Bacellar O

更新日期：2015-03-01 00:00:00

abstract：:Previous studies have shown that a mutant (designated C4) of Streptococcus mutans 6715 wild type (WT) is defective in glucosyltransferase (GTF)-synthesized insoluble glucan and is avirulent in gnotobiotic rats. This study investigated the factors which would render this mutant virulent in gnotobiotic rats. Microbial a...

journal_title：Infection and immunity

authors： Hirasawa M,Kiyono H,Shiota T,Hull RA,Curtiss R 3rd,Michalek SM,McGhee JR

更新日期：1980-03-01 00:00:00

abstract：:Highly purified protein antigens are usually poor immunogens; in practice, adjuvants are needed to obtain satisfactory immune responses. Plasmodium yoelii 19-kDa merozoite surface protein 1 (MSP1(19)) is a weak antigen, but mice vaccinated with this antigen in strong adjuvants can survive an otherwise lethal parasite ...

journal_title：Infection and immunity

authors： Ogun SA,Dumon-Seignovert L,Marchand JB,Holder AA,Hill F

更新日期：2008-08-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae serotype 7 strains are shown to spontaneously lose cytolytic activity with a frequency of approximately 10(-4). The phenotypic change is associated with the loss of approximately 8.5 kbp of chromosomal DNA. A genomic fragment encoding the cytolysin and its flanking sequences was cloned ...

journal_title：Infection and immunity

authors： Anderson C,Potter AA,Gerlach GF

更新日期：1991-11-01 00:00:00

abstract：:We studied seven strains of group G streptococci isolated from clinically severe bacteremic infections in six intravenous drug abusers. These group G strains multiplied luxuriantly in fresh human blood. On electron microscopy, they exhibited surface fibrillae similar to those observed in M-protein-rich group A strepto...

journal_title：Infection and immunity

authors： Bisno AL,Craven DE,McCabe WR

更新日期：1987-03-01 00:00:00

abstract：:Because combined administration of intramuscular and intravenous interferon has been partially successful in the incubationary treatment of rabies, the effect of direct interferon administration into the cerebrospinal fluid space was tested. After injecting 1,800 U of interferon into the cisterna magna or the lateral ...

journal_title：Infection and immunity

authors： Ho M,Nash C,Morgan CW,Armstrong JA,Carroll RG,Postic B

更新日期：1974-02-01 00:00:00

abstract：:Antisera against isolated cell surface preparations (PCSP-As) of Leishmania donovani promastigotes were used to detect extracellular antigens produced during the growth of these organisms in four different growth media. The PCSP-As precipitated two major antigenically identical but electrophoretically distinct compone...

journal_title：Infection and immunity

authors： Kaneshiro ES,Gottlieb M,Dwyer DM

更新日期：1982-08-01 00:00:00

abstract：:The obligate intracellular parasite Toxoplasma gondii can actively infect any nucleated cell type, including cells from the immune system. The rapid transfer of T. gondii from infected dendritic cells to effector natural killer (NK) cells may contribute to the parasite's sequestration and shielding from immune recogni...

journal_title：Infection and immunity

authors： Sultana MA,Du A,Carow B,Angbjär CM,Weidner JM,Kanatani S,Fuks JM,Muliaditan T,James J,Mansfield IO,Campbell TM,Liu L,Kadri N,Lambert H,Barragan A,Chambers BJ

更新日期：2017-09-20 00:00:00

abstract：:Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from S. pneumoniae TIGR4...

journal_title：Infection and immunity

authors： Chan WY,Entwisle C,Ercoli G,Ramos-Sevillano E,McIlgorm A,Cecchini P,Bailey C,Lam O,Whiting G,Green N,Goldblatt D,Wheeler JX,Brown JS

更新日期：2019-02-21 00:00:00

abstract：:The production of type 1 fimbriae in Salmonella enterica serovar Typhimurium is controlled, in part, by three proteins, FimZ, FimY, and FimW. Amino acid sequence analysis indicates that FimZ belongs to the family of bacterial response regulators of two-component systems. In these studies, we have demonstrated that int...

journal_title：Infection and immunity

authors： Zeiner SA,Dwyer BE,Clegg S

更新日期：2013-12-01 00:00:00