Rate of Clearance of Vibrio fetus var. venerealis in the Rabbit.

abstract：:Treponema hyodysenteriae was shown to attach to mouse peritoneal cells in the absence of serum opsonins in vitro. If serotype-specific antiserum from pigs was added to the media and treponemes of that corresponding serotype were employed in the assay, the amount of attachment increased an average of 3.7 times that of ...

journal_title：Infection and immunity

authors： Nuessen ME,Joens LA

更新日期：1982-12-01 00:00:00

abstract：:The need for agents designed to modify immune response in the treatment of patients with viral infection, immunodeficiency, or cancer prompted the present study on the mechanisms of action of isoprinosine, a compound developed for antiviral use and whose therapeutic activity may involve the immune system. The effect o...

journal_title：Infection and immunity

authors： Hadden JW,Hadden EM,Coffey RG

更新日期：1976-02-01 00:00:00

abstract：:Live or heat-killed cells of Streptococcus mutans specifically adhere to dextran previously synthesized on glass surfaces by the action of extracellular dextransucrase. ...

journal_title：Infection and immunity

authors： Kuramitsu HK

更新日期：1974-04-01 00:00:00

abstract：:Trehalose 6,6'-dimycolate (TDM) plays important roles in the development of granulomatous inflammation during infection with Mycobacterium spp., Rhodococcus spp., etc. To reveal the augmenting effect of TDM on vascular endothelial growth factor (VEGF) production and neovascularization, we investigated murine granuloma...

journal_title：Infection and immunity

authors： Sakaguchi I,Ikeda N,Nakayama M,Kato Y,Yano I,Kaneda K

更新日期：2000-04-01 00:00:00

abstract：:Clostridium perfringens enterotoxin (CPE), a single polypeptide of 319 amino acids, has a unique multistep mechanism of action. In the first step, CPE binds to claudin proteins and/or a 50-kDa eukaryotic membrane protein receptor, forming a small ( approximately 90-kDa) complex. This small complex apparently then asso...

journal_title：Infection and immunity

authors： Kokai-Kun JF,Benton K,Wieckowski EU,McClane BA

更新日期：1999-11-01 00:00:00

abstract：:A Gram-negative, filamentous, rod-shaped bacillus which failed to grow in cell-free media was isolated in apparently pure culture from the bronchial scraping and washing of a laboratory rat suffering from chronic respiratory disease by inoculating embryonated chicken eggs via the allantoic route. None of the embryos d...

journal_title：Infection and immunity

authors： Ganaway JR,Spencer TH,Moore TD,Allen AM

更新日期：1985-02-01 00:00:00

abstract：:Cells of Yersinia pestis strain EV76 are known to cease growth after a shift from 26 to 37 degrees C in neutral Ca2+-deficient medium; this effect is potentiated by Mg2+. With 2.5 mM Mg2+ and no added Ca2+, restriction was relaxed at elevated pH at which maximum cell yields occurred in the presence of 20 mM exogenous ...

journal_title：Infection and immunity

authors： Zahorchak RJ,Brubaker RR

更新日期：1982-12-01 00:00:00

abstract：:Suitability of the rhesus monkey (Macaca mulatta) as an experimental host for evaluation of vaccines against airborne infection with Mycobacterium tuberculosis strain H37Rv was investigated. Nonvaccinated monkeys were exposed to estimated doses of 12, 25, or 49 units of H37Rv in a modified Henderson apparatus, and the...

journal_title：Infection and immunity

authors： Barclay WR,Anacker RL,Brehmer W,Leif W,Ribi E

更新日期：1970-11-01 00:00:00

abstract：:The ability of a pathogen to evade neutrophil phagocytic killing mechanisms is critically important for dissemination and establishment of a systemic infection. Understanding how pathogens overcome these innate defenses is essential for the development of optimal therapeutic strategies for invasive infections. CpsY is...

journal_title：Infection and immunity

authors： Allen JP,Neely MN

更新日期：2012-05-01 00:00:00

abstract：:We attempted to induce experimental arthritis in rats by systematically testing the effect of Yersinia infections in five strains of rats, using the intragastric, intraperitoneal, and intravenous routes of inoculation. We observed that Lewis rats which were given 10(4) to 10(5) Yersinia enterocolitica WA organisms via...

journal_title：Infection and immunity

authors： Hill JL,Yu DT

更新日期：1987-03-01 00:00:00

abstract：:We found that oral immunization with flagellum-defective mutant strains of Salmonella enterica serovar Typhimurium with the ClpXP-deficient background protected mice against oral challenge with the virulent strain. These data indicate that Salmonella flagellin is not a dominant protective antigen in oral immunization ...

journal_title：Infection and immunity

authors： Kodama C,Matsui H

更新日期：2004-04-01 00:00:00

abstract：:Salmonella enterica serovar Typhimurium employs two different type III secretion systems (TTSS) encoded within Salmonella pathogenicity islands 1 and 2 (SPI1 and SPI2) for targeting of effector proteins into the cytosol of eukaryotic cells during different stages of the infection cycle. The SPI1 TTSS translocates viru...

journal_title：Infection and immunity

authors： Panthel K,Meinel KM,Domènech VE,Retzbach H,Igwe EI,Hardt WD,Rüssmann H

更新日期：2005-01-01 00:00:00

abstract：:The mechanism by which hamsters acquire resistance to yaws or frambesia is poorly understood. This investigation has shown that immune lymphoid cells (spleen and lymph node) could confer on hamsters resistance to infection with Treponema pertenue. Treatment of these immune cells with a specific antithymocyte serum (AT...

journal_title：Infection and immunity

authors： Chan JK,Schell RF,LeFrock JL

更新日期：1979-07-01 00:00:00

abstract：:Nine goats were injected transthoracically with Pasteurella haemolytica A1 to determine if an extracellular bacterial enzyme, neuraminidase, was produced in vivo during infection with this organism. The principal group of goats (n = 9) each received 1 ml of 7.25 x 10(5) live P. haemolytica A1 cells in polyacrylate bea...

journal_title：Infection and immunity

authors： Straus DC,Purdy CW

更新日期：1994-10-01 00:00:00

abstract：:BCG vaccines are a family of closely related daughter strains of an attenuated isolate of Mycobacterium bovis derived by in vitro passage from 1908 to 1921. During subsequent laboratory propagation of the vaccine strain until its lyophilization in 1961, BCG Pasteur underwent at least seven further genomic mutations. T...

journal_title：Infection and immunity

authors： Belley A,Alexander D,Di Pietrantonio T,Girard M,Jones J,Schurr E,Liu J,Sherman DR,Behr MA

更新日期：2004-05-01 00:00:00

abstract：:Haemophilus ducreyi is resistant to killing by normal serum antibody and complement. We discovered an H. ducreyi outer membrane protein required for expression of serum resistance and termed it DsrA (for "ducreyi serum resistance A"). The dsrA locus was cloned, sequenced, and mutagenized. An isogenic mutant (FX517) of...

journal_title：Infection and immunity

authors： Elkins C,Morrow KJ Jr,Olsen B

更新日期：2000-03-01 00:00:00

abstract：:High-density oligonucleotide microarrays are widely used to study gene expression in cells exposed to a variety of pathogens. This study addressed the global genome-wide transcriptional activation of genes in hosts infected in vivo, which result in radically different clinical outcomes. We present an analysis of the g...

journal_title：Infection and immunity

authors： Schaecher K,Kumar S,Yadava A,Vahey M,Ockenhouse CF

更新日期：2005-09-01 00:00:00

abstract：:We investigated the ability of two overlapping fragments of staphylococcal enterotoxin B (SEB), which encompass the whole toxin, to induce protection and also examined if passive transfer of chicken anti-SEB antibodies raised against the holotoxin could protect rhesus monkeys against aerosolized SEB. Although both fra...

journal_title：Infection and immunity

authors： LeClaire RD,Hunt RE,Bavari S

更新日期：2002-05-01 00:00:00

abstract：:It is well established that activating-type Fc receptors for immunoglobulin G (FcgammaR), such as FcgammaRI and FcgammaRIII, are essential for inducing inflammatory responses. On the other hand, a unique inhibitory FcgammaR, FcgammaRIIB, inhibits intracellular signaling upon engagement of immunoglobulin G-immune compl...

journal_title：Infection and immunity

authors： Henriques-Pons A,Olivieri BP,Oliveira GM,Daëron M,de Araújo-Jorge TC

更新日期：2005-08-01 00:00:00

abstract：:(DBA/N[female] X CBA/2[male])F1 males have been reported to be deficient in producing antibodies against a number of antigens, including carbohydrates (I. Scher, Adv. Immunol. 35:1-71, 1982). We show that F1 male mice, in contrast to females, made less lipopolysaccharide (LPS)-specific antibodies after immunization wi...

journal_title：Infection and immunity

authors： Zweerink HJ,Gammon MC,Hutchison CF,Jackson JJ,Pier GB,Puckett JM,Sewell TJ,Sigal NH

更新日期：1988-05-01 00:00:00

abstract：:Protozoan parasites of the genus Leishmania exist as obligatory intracellular amastigotes and invade macrophages and Langerhans cells, the dendritic cells of the skin. Langerhans cells are much more efficient in presenting Leishmania major antigen to T cells than macrophages are and have the unique ability to retain p...

journal_title：Infection and immunity

authors： Flohé S,Lang T,Moll H

更新日期：1997-08-01 00:00:00

abstract：:In experimental Leishmania donovani infection in BALB/c mice, initial susceptibility gives way to T-cell-dependent acquired resistance and eventual control over visceral infection. Since various cytokines appear to underlie the host response to Leishmania infection, we examined infected liver tissue for gene expressio...

journal_title：Infection and immunity

authors： Miralles GD,Stoeckle MY,McDermott DF,Finkelman FD,Murray HW

更新日期：1994-03-01 00:00:00

abstract：:Interactions between bacteria and salivary components are thought to be important in the establishment and ecology of the oral microflora. alpha-Amylase, the predominant salivary enzyme in humans, binds to Streptococcus gordonii, a primary colonizer of the tooth. Previous studies have implicated this interaction in ad...

journal_title：Infection and immunity

authors： Rogers JD,Palmer RJ Jr,Kolenbrander PE,Scannapieco FA

更新日期：2001-11-01 00:00:00

abstract：:Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, ...

journal_title：Infection and immunity

authors： Rivas AJ,Balado M,Lemos ML,Osorio CR

更新日期：2013-09-01 00:00:00

abstract：:The fungus Cryptococcus neoformans has emerged as a major cause of meningoencephalitis worldwide. Host response to the fungus involves both innate and adaptive immunity, but fungal genes that modulate these processes are poorly understood. Previous studies demonstrated attenuated virulence of a mutant of a virulence-a...

journal_title：Infection and immunity

authors： Qiu J,Olszewski MA,Williamson PR

更新日期：2013-03-01 00:00:00

abstract：:Chlamydia trachomatis serovar L2 is an obligate intracellular bacterium which is internalized in target epithelial cells by endocytosis and resides within a membrane-bound vesicle. Over the next several hours following entry, individual serovar L2-containing vesicles fuse with one another to form a single membrane-bou...

journal_title：Infection and immunity

authors： Schramm N,Bagnell CR,Wyrick PB

更新日期：1996-04-01 00:00:00

abstract：:Infection with gram-negative monocytotropic Ehrlichia strains results in a fatal toxic shock-like syndrome characterized by a decreased number of Ehrlichia-specific CD4(+) Th1 cells, the expansion of tumor necrosis factor alpha (TNF-alpha)-producing CD8(+) T cells, and the systemic overproduction of interleukin-10 (IL...

journal_title：Infection and immunity

authors： Ismail N,Crossley EC,Stevenson HL,Walker DH

更新日期：2007-09-01 00:00:00

abstract：:Legionnaires' disease is clinically manifested as severe pneumonia caused by Legionella pneumophila. However, the dendritic cell (DC)-centered immunological framework of the host defense against L. pneumophila has not been fully delineated. For this study, we focused on a potent chemoattractant for lymphocytes, fracta...

journal_title：Infection and immunity

authors： Kikuchi T,Andarini S,Xin H,Gomi K,Tokue Y,Saijo Y,Honjo T,Watanabe A,Nukiwa T

更新日期：2005-09-01 00:00:00

abstract：:Recent evidence suggests that immune-mediated gastric epithelial cell apoptosis through Fas-Fas ligand interactions participates in Helicobacter pylori disease pathogenesis. To define the role of Fas signaling in vivo, H. pylori strain SS1 infection in C57BL/6 mice was compared to that in mice deficient in the Fas lig...

journal_title：Infection and immunity

authors： Jones NL,Day AS,Jennings H,Shannon PT,Galindo-Mata E,Sherman PM

更新日期：2002-05-01 00:00:00

abstract：:The generation of leukotrienes (LTC4, LTD4, LTE4, and LTB4; 12-epi-LTB4 isomer) from human granulocytes by thiol-activated toxins (streptolysin O, alveolysin from Bacillus alvei, and theta toxin from Clostridium perfringens) is described. The release occurs under noncytolytic conditions. Although LTB4 is the major com...

journal_title：Infection and immunity

authors： Bremm KD,König W,Pfeiffer P,Rauschen I,Theobald K,Thelestam M,Alouf JE

更新日期：1985-12-01 00:00:00