Trehalose 6,6'-dimycolate (Cord factor) enhances neovascularization through vascular endothelial growth factor production by neutrophils and macrophages.

abstract：:The ultrastructural appearance of the "halozone" formed at the interface between the spotted fever agent Rickettsia rickettsii and the cytoplasm of persistently infected cultured vole cells (Microtus pennsylvanicus) was studied by transmission electron microscopy. In sections of epoxy-embedded specimens stained with u...

journal_title：Infection and immunity

authors： Todd WJ,Burgdorfer W,Wray GP

更新日期：1983-09-01 00:00:00

abstract：:In order to approximate and adhere to mucosal epithelial cells, Candida must traverse the overlying mucus layer. Interactions of Candida species with mucin and human buccal epithelial cells (BECs) were thus investigated in vitro. Binding of the Candida species to purified small intestinal mucin showed a close correlat...

journal_title：Infection and immunity

authors： de Repentigny L,Aumont F,Bernard K,Belhumeur P

更新日期：2000-06-01 00:00:00

abstract：:Anti-NMDA receptor (NMDAR) autoantibodies have been postulated to play a role in the pathogenesis of NMDAR hypofunction, which contributes to the etiology of psychotic symptoms. Toxoplasma gondii is a pathogen implicated in psychiatric disorders and associated with elevation of NMDAR autoantibodies. However, it remain...

journal_title：Infection and immunity

authors： Li Y,Viscidi RP,Kannan G,McFarland R,Pletnikov MV,Severance EG,Yolken RH,Xiao J

更新日期：2018-09-21 00:00:00

abstract：:In vivo expression of pili by Escherichia coli in the urine of 41 adults with lower urinary tract infections was analyzed by immunostaining with polyclonal antiserum to type 1 and P pili. Type 1 pili were detected in 31 of 41 urine specimens, while P pili were detected in 6 of 18 specimens. The piliation status of bac...

journal_title：Infection and immunity

authors： Kisielius PV,Schwan WR,Amundsen SK,Duncan JL,Schaeffer AJ

更新日期：1989-06-01 00:00:00

abstract：:Tox-+ staphylococcal strains, as opposed to Tox-minus strains, produce epidermal exfoliation within 18 h after direct subcutaneous or intraperitoneal injection into newborn mice. The extracellular product responsible for exfoliation is termed exfoliative toxin (ET). When culture supernatant fluid from the plasmid-cure...

journal_title：Infection and immunity

authors： Keyhani M,Rogolsky M,Wiley BB,Glasgow LA

更新日期：1975-07-01 00:00:00

abstract：:Strategies to limit complement deposition on Streptococcus pneumoniae are established as virulence features for invasive disease, but their role in respiratory tract infection requires further analysis. We evaluated complement C3 protein deposition on discordant S. pneumoniae isolates of the same serotype (6A) and the...

journal_title：Infection and immunity

authors： Sabharwal V,Ram S,Figueira M,Park IH,Pelton SI

更新日期：2009-03-01 00:00:00

abstract：:Phagocytosis of unopsonized Salmonella typhimurium 395, MR-10, opsonized Salmonella typhimurium 395 MS, and Staphylococcus epidermidis by rabbit polymorphonuclear leukocytes was inhibited by heparin at concentrations as low as 0.5 U/ml. Inhibition was dose dependent and nearly complete at 20 U/ml. Provided that hepari...

journal_title：Infection and immunity

authors： Victor M,Weiss J,Elsbach P

更新日期：1981-04-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:The goal of this study is to evaluate the contribution of mast cells to Helicobacter pylori immunity in a model of vaccine-induced protection. Mast cell-deficient Kitl(Sl)/Kitl(Sl-d) and control mice were immunized with H. pylori sonicate plus cholera toxin and challenged with H. pylori, and the bacterial loads, infla...

journal_title：Infection and immunity

authors： Ding H,Nedrud JG,Wershil B,Redline RW,Blanchard TG,Czinn SJ

更新日期：2009-12-01 00:00:00

abstract：:The polysaccharide antigen preparations from serotype a and serotype d strains of Streptococcus mutans contained both a serotype-specific antigenic determinant and a common a-d antigenic determinant, as demonstrated by agar gel diffusion studies and a quantitative cross-precipitin assay. The chromatographically purifi...

journal_title：Infection and immunity

authors： Linzer R,Mukasa H,Slade HD

更新日期：1975-10-01 00:00:00

abstract：:The amino acid sequence of heat-stable enterotoxin produced by enterotoxigenic Escherichia coli 18D has been revised. Amino acids originally assigned to positions 11 and 18, i.e., Tyr and Asn, respectively, were found to occupy positions 18 and 11, respectively. Thus all heat-stable enterotoxins composed of 18 amino a...

journal_title：Infection and immunity

authors： Thompson MR,Giannella RA

更新日期：1985-03-01 00:00:00

abstract：:The role of the hypothalamus-pituitary-adrenal (HPA) axis in regulating the growth of Mycobacterium avium in Mycobacterium bovis BCG-resistant and -susceptible congenic mice was evaluated. Restraint was used to activate the HPA axis, which resulted in an increase in the level of corticosterone in the plasma. Activatio...

journal_title：Infection and immunity

authors： Brown DH,Sheridan J,Pearl D,Zwilling BS

更新日期：1993-11-01 00:00:00

abstract：:Immunity to pneumococcal colonization in mice by exposure to live or killed pneumococci has been shown to be antibody independent but dependent on CD4+ T cells. Here we show that intranasal immunization with pneumococcal proteins (pneumococcal surface protein C, adhesin A, and a pneumolysoid) can elicit a similar mech...

journal_title：Infection and immunity

authors： Basset A,Thompson CM,Hollingshead SK,Briles DE,Ades EW,Lipsitch M,Malley R

更新日期：2007-11-01 00:00:00

abstract：:Acid hydrolysates of the type-specific main (TM) antigen isolated from Leptospira kremastos strain Kyoto showed a considerable inhibition of complement fixation reaction between TM antigen and anti-strain Kyoto serum. A fraction of 2 N HCl hydrolysate containing exclusively a large amount of neutral sugars showed no i...

journal_title：Infection and immunity

authors： Adachi Y,Yanagawa R

更新日期：1975-06-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae serotype 7 strains are shown to spontaneously lose cytolytic activity with a frequency of approximately 10(-4). The phenotypic change is associated with the loss of approximately 8.5 kbp of chromosomal DNA. A genomic fragment encoding the cytolysin and its flanking sequences was cloned ...

journal_title：Infection and immunity

authors： Anderson C,Potter AA,Gerlach GF

更新日期：1991-11-01 00:00:00

abstract：:Black melanin-like pigments are produced by several neurotropic fungi, including Cryptococcus neoformans. Pigment production is associated with virulence. In media containing phenolic substrates such as L-dopa, C. neoformans cells become black as a result of pigment accumulation. Pigmented and nonpigmented C. neoforma...

journal_title：Infection and immunity

authors： Wang Y,Aisen P,Casadevall A

更新日期：1995-08-01 00:00:00

abstract：:Considerable evidence supports the concept that CD4(+) T cells are important in sarcoidosis pathogenesis, but the antigens responsible for the observed Th1 immunophenotype remain elusive. The epidemiologic association with bioaerosols and the presence of granulomatous inflammation support consideration of mycobacteria...

journal_title：Infection and immunity

authors： Oswald-Richter KA,Culver DA,Hawkins C,Hajizadeh R,Abraham S,Shepherd BE,Jenkins CA,Judson MA,Drake WP

更新日期：2009-09-01 00:00:00

abstract：:Splenic lymphocytes from cytomegalovirus-infected mice lost their in vitro proliferative responses to cytomegalovirus antigen within 3 h after in vivo treatment with antilymphocyte globulin and prednisolone. The response was inhibited when the agents were administered separately or together, and inhibition persisted t...

journal_title：Infection and immunity

authors： Mattsson DM,Howard RJ,Balfour HH Jr

更新日期：1980-12-01 00:00:00

abstract：:In studies of immunity to malaria, the absence of febrile malaria is commonly considered evidence of "protection." However, apparent "protection" may be due to a lack of exposure to infective mosquito bites or due to immunity. We studied a cohort that was given curative antimalarials before monitoring began and docume...

journal_title：Infection and immunity

authors： Bejon P,Warimwe G,Mackintosh CL,Mackinnon MJ,Kinyanjui SM,Musyoki JN,Bull PC,Marsh K

更新日期：2009-05-01 00:00:00

abstract：:Archival gastric tissues from 10 of 39 gnotobiotic piglets colonized with Helicobacter pylori 26695 contained stromal leukocytic inflammation along with ulcers and erosions. In contrast, gastric tissues from 54 archival control piglets were devoid of both inflammation and ulcers. These data confirm the hypothesis that...

journal_title：Infection and immunity

authors： Krakowka S,Eaton KA,Rings DM

更新日期：1995-06-01 00:00:00

abstract：:We found that serum samples from patients with different clinical forms of American cutaneous leishmaniasis (ACL) contained immunoglobulin G and immunoglobulin M antibodies which reacted with laminin but not with various other purified connective tissue components, such as collagen types I, III, IV, and V and fibronec...

journal_title：Infection and immunity

authors： Avila JL,Rojas M,Rieber M

更新日期：1984-01-01 00:00:00

abstract：:The serum opacity factor (SOF) of Streptococcus pyogenes is a serotyping tool and pathogenesis factor. Using SOF-coated latex beads in cell adherence assays and antiserum directed against SOF in S. pyogenes-HEp-2 cell adherence inhibition experiments, we demonstrate SOF involvement in the fibronectin-mediated adherenc...

journal_title：Infection and immunity

authors： Oehmcke S,Podbielski A,Kreikemeyer B

更新日期：2004-07-01 00:00:00

abstract：:Toxoplasma gondii infects both hematopoietic and nonhematopoietic cells and can cause cerebral and ocular toxoplasmosis, as a result of either congenital or postnatally acquired infections. Host protection likely acts at both cellular levels to control the parasite. CD40 is a key factor for protection against cerebral...

journal_title：Infection and immunity

authors： Van Grol J,Muniz-Feliciano L,Portillo JA,Bonilha VL,Subauste CS

更新日期：2013-06-01 00:00:00

abstract：:Mucin glycoproteins are secreted in large amounts by the intestinal epithelium and constitute an efficient component of innate immune defenses to promote homeostasis and protect against enteric pathogens. In this study, our objective was to investigate how the bacterial enteropathogen Shigella flexneri, which causes b...

journal_title：Infection and immunity

authors： Sperandio B,Fischer N,Joncquel Chevalier-Curt M,Rossez Y,Roux P,Robbe Masselot C,Sansonetti PJ

更新日期：2013-10-01 00:00:00

abstract：:When tested for their activity in suppressing the acquisition of immunity during acute Besnoitia infection of hamsters, antilymphocyte serum (ALS), aminopterin, cyclophosphamide, cortisol, and whole-body irradiation were the most active agents and effectively blocked the development of immunity during 4 to 12 days of ...

journal_title：Infection and immunity

authors： Wilson HR,Frenkel JK

更新日期：1971-06-01 00:00:00

abstract：:Saccharomyces boulardii is a nonpathogenic yeast that protects against antibiotic-associated diarrhea and recurrent Clostridium difficile colitis. The administration of C. difficile toxoid A by gavage to S. boulardii-fed BALB/c mice caused a 1.8-fold increase in total small intestinal immunoglobulin A levels (P = 0.00...

journal_title：Infection and immunity

authors： Qamar A,Aboudola S,Warny M,Michetti P,Pothoulakis C,LaMont JT,Kelly CP

更新日期：2001-04-01 00:00:00

abstract：:Two virulence factors of Listeria monocytogenes, listeriolysin O (LLO) and phosphatidylinositol-specific phospholipase C (PI-PLC), mediate escape of this pathogen from the phagocytic vacuole of macrophages, thereby allowing the bacterium access to the host cell cytosol for growth and spread to neighboring cells. We ch...

journal_title：Infection and immunity

authors： Wei Z,Schnupf P,Poussin MA,Zenewicz LA,Shen H,Goldfine H

更新日期：2005-10-01 00:00:00

abstract：:To evaluate the roles of the infectious agent and the host in the pathogensis of Salmonella-associated arthritis (SAA), 1O(3) to 10(6) heat-killed Salmonella enteritidis were injected directly into involved carpal joints in normal and actively immunized rats and in hosts adoptively immunized by the intravenous transfe...

journal_title：Infection and immunity

authors： Volkman A,Collins FM

更新日期：1976-04-01 00:00:00

abstract：:Chemokines (CK) are potent leukocyte activators and chemoattractants and aid in granuloma formation, functions critical for the immune response to Mycobacterium tuberculosis. We hypothesized that infection of alveolar macrophages (AM) with different strains of M. tuberculosis elicits distinct profiles of CK, which cou...

journal_title：Infection and immunity

authors： Saukkonen JJ,Bazydlo B,Thomas M,Strieter RM,Keane J,Kornfeld H

更新日期：2002-04-01 00:00:00

abstract：:Wild-type Bordetella bronchiseptica and a bvg mutant strain were used for invasion and survival experiments in human Caco-2 and A549 epithelial cells. Both bacterial strains were able to enter and persist within the host cells for at least a week. A significant proportion of the bacteria from both B. bronchiseptica st...

journal_title：Infection and immunity

authors： Schipper H,Krohne GF,Gross R

更新日期：1994-07-01 00:00:00